A citation-based method for searching scientific literature

Diego Loayza, Titia De Lange. Nature 2003
Times Cited: 477







List of co-cited articles
1125 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity




How shelterin protects mammalian telomeres.
Wilhelm Palm, Titia de Lange. Annu Rev Genet 2008
36


Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
30

PTOP interacts with POT1 and regulates its localization to telomeres.
Dan Liu, Amin Safari, Matthew S O'Connor, Doug W Chan, Andrew Laegeler, Jun Qin, Zhou Songyang. Nat Cell Biol 2004
307
30

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex.
Jeffrey Zheng-Sheng Ye, Dirk Hockemeyer, Andrew N Krutchinsky, Diego Loayza, Sarah M Hooper, Brian T Chait, Titia de Lange. Genes Dev 2004
310
30

The POT1-TPP1 telomere complex is a telomerase processivity factor.
Feng Wang, Elaine R Podell, Arthur J Zaug, Yuting Yang, Paul Baciu, Thomas R Cech, Ming Lei. Nature 2007
452
29


DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
953
27

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
627
26

The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.
Jayakrishnan Nandakumar, Caitlin F Bell, Ina Weidenfeld, Arthur J Zaug, Leslie A Leinwand, Thomas R Cech. Nature 2012
197
26

TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
Huawei Xin, Dan Liu, Ma Wan, Amin Safari, Hyeung Kim, Wen Sun, Matthew S O'Connor, Zhou Songyang. Nature 2007
350
26

Recent expansion of the telomeric complex in rodents: Two distinct POT1 proteins protect mouse telomeres.
Dirk Hockemeyer, Jan-Peter Daniels, Hiroyuki Takai, Titia de Lange. Cell 2006
276
26

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
255
24

Control of human telomere length by TRF1 and TRF2.
A Smogorzewska, B van Steensel, A Bianchi, S Oelmann, M R Schaefer, G Schnapp, T de Lange. Mol Cell Biol 2000
561
24

Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
23


TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Franklin L Zhong, Luis F Z Batista, Adam Freund, Matthew F Pech, Andrew S Venteicher, Steven E Artandi. Cell 2012
183
22

Telomere protection by TPP1/POT1 requires tethering to TIN2.
Kaori K Takai, Tatsuya Kibe, Jill R Donigian, David Frescas, Titia de Lange. Mol Cell 2011
135
21

POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia.
Andrew J Ramsay, Víctor Quesada, Miguel Foronda, Laura Conde, Alejandra Martínez-Trillos, Neus Villamor, David Rodríguez, Agnieszka Kwarciak, Cecilia Garabaya, Mercedes Gallardo,[...]. Nat Genet 2013
176
20

POT1 loss-of-function variants predispose to familial melanoma.
Carla Daniela Robles-Espinoza, Mark Harland, Andrew J Ramsay, Lauren G Aoude, Víctor Quesada, Zhihao Ding, Karen A Pooley, Antonia L Pritchard, Jessamy C Tiffen, Mia Petljak,[...]. Nat Genet 2014
203
20


A DNA damage checkpoint response in telomere-initiated senescence.
Fabrizio d'Adda di Fagagna, Philip M Reaper, Lorena Clay-Farrace, Heike Fiegler, Philippa Carr, Thomas Von Zglinicki, Gabriele Saretzki, Nigel P Carter, Stephen P Jackson. Nature 2003
19

TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
19

Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma.
Jianxin Shi, Xiaohong R Yang, Bari Ballew, Melissa Rotunno, Donato Calista, Maria Concetta Fargnoli, Paola Ghiorzo, Brigitte Bressac-de Paillerets, Eduardo Nagore, Marie Francoise Avril,[...]. Nat Genet 2014
183
19

Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres.
Ling Wu, Asha S Multani, Hua He, Wilfredo Cosme-Blanco, Yu Deng, Jian Min Deng, Olga Bachilo, Sen Pathak, Hedioshi Tahara, Susan M Bailey,[...]. Cell 2006
293
19

Shelterin-Mediated Telomere Protection.
Titia de Lange. Annu Rev Genet 2018
181
19


TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.
Eladio Abreu, Elena Aritonovska, Patrick Reichenbach, Gaël Cristofari, Brad Culp, Rebecca M Terns, Joachim Lingner, Michael P Terns. Mol Cell Biol 2010
163
18

Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
18


Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
169
17

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
Paula Martínez, Maria Thanasoula, Purificación Muñoz, Chunyan Liao, Agueda Tejera, Carolyn McNees, Juana M Flores, Oscar Fernández-Capetillo, Madalena Tarsounas, Maria A Blasco. Genes Dev 2009
260
17

Telomere protection by mammalian Pot1 requires interaction with Tpp1.
Dirk Hockemeyer, Wilhelm Palm, Tobias Else, Jan-Peter Daniels, Kaori K Takai, Jeffrey Z-S Ye, Catherine E Keegan, Titia de Lange, Gary D Hammer. Nat Struct Mol Biol 2007
130
17

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
D Broccoli, A Smogorzewska, L Chong, T de Lange. Nat Genet 1997
705
17


TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
Rachel Litman Flynn, Richard C Centore, Roderick J O'Sullivan, Rekha Rai, Alice Tse, Zhou Songyang, Sandy Chang, Jan Karlseder, Lee Zou. Nature 2011
214
16

In vivo stoichiometry of shelterin components.
Kaori K Takai, Sarah Hooper, Stephanie Blackwood, Rita Gandhi, Titia de Lange. J Biol Chem 2010
151
16

POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end.
Dirk Hockemeyer, Agnel J Sfeir, Jerry W Shay, Woodring E Wright, Titia de Lange. EMBO J 2005
213
15


The telomere syndromes.
Mary Armanios, Elizabeth H Blackburn. Nat Rev Genet 2012
536
15

TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.
Jeffrey Zheng-Sheng Ye, Jill R Donigian, Megan van Overbeek, Diego Loayza, Yan Luo, Andrew N Krutchinsky, Brian T Chait, Titia de Lange. J Biol Chem 2004
216
14

The human CST complex is a terminator of telomerase activity.
Liuh-Yow Chen, Sophie Redon, Joachim Lingner. Nature 2012
188
14

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.
Alec N Sexton, Samuel G Regalado, Christine S Lai, Gregory J Cost, Colleen M O'Neil, Fyodor D Urnov, Philip D Gregory, Rudolf Jaenisch, Kathleen Collins, Dirk Hockemeyer. Genes Dev 2014
72
19

Germline mutations in shelterin complex genes are associated with familial glioma.
Matthew N Bainbridge, Georgina N Armstrong, M Monica Gramatges, Alison A Bertuch, Shalini N Jhangiani, Harsha Doddapaneni, Lora Lewis, Joseph Tombrello, Spyros Tsavachidis, Yanhong Liu,[...]. J Natl Cancer Inst 2014
123
14

TIN2, a new regulator of telomere length in human cells.
S H Kim, P Kaminker, J Campisi. Nat Genet 1999
382
14

Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
Claus M Azzalin, Patrick Reichenbach, Lela Khoriauli, Elena Giulotto, Joachim Lingner. Science 2007
799
13

A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li-Fraumeni-like families.
Oriol Calvete, Paula Martinez, Pablo Garcia-Pavia, Carlos Benitez-Buelga, Beatriz Paumard-Hernández, Victoria Fernandez, Fernando Dominguez, Clara Salas, Nuria Romero-Laorden, Jesus Garcia-Donas,[...]. Nat Commun 2015
78
16

Telomere protection by TPP1 is mediated by POT1a and POT1b.
Tatsuya Kibe, Gail A Osawa, Catherine E Keegan, Titia de Lange. Mol Cell Biol 2010
79
15


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.