Biao Wang, Yang Xiao, Bei Bei Ding, Na Zhang, Xiao bin Yuan, Lü Gui, Kai Xian Qian, Shumin Duan, Zhengjun Chen, Yi Rao, Jian Guo Geng. Cancer Cell 2003
Times Cited: 310
Times Cited: 310
Times Cited
Times Co-cited
Similarity
Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance.
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
K Brose, K S Bland, K H Wang, D Arnott, W Henzel, C S Goodman, M Tessier-Lavigne, T Kidd. Cell 1999
30
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
Christopher A Jones, Nyall R London, Haoyu Chen, Kye Won Park, Dominique Sauvaget, Rebecca A Stockton, Joshua D Wythe, Wonhee Suh, Frederic Larrieu-Lahargue, Yoh-Suke Mukouyama,[...]. Nat Med 2008
27
Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors.
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
T Kidd, K Brose, K J Mitchell, R D Fetter, M Tessier-Lavigne, C S Goodman, G Tear. Cell 1998
23
The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors.
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
J Y Wu, L Feng, H T Park, N Havlioglu, L Wen, H Tang, K B Bacon, Jiang Zh, Zhang Xc, Y Rao. Nature 2001
22
Robo4 is a vascular-specific receptor that inhibits endothelial migration.
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
Kye Won Park, Clayton M Morrison, Lise K Sorensen, Christopher A Jones, Yi Rao, Chi-Bin Chien, Jane Y Wu, Lisa D Urness, Dean Y Li. Dev Biol 2003
22
Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
Nicolas Rama, Alexandre Dubrac, Thomas Mathivet, Róisín-Ana Ní Chárthaigh, Gael Genet, Brunella Cristofaro, Laurence Pibouin-Fragner, Le Ma, Anne Eichmann, Alain Chédotal. Nat Med 2015
22
Slit-Robo signaling mediates lymphangiogenesis and promotes tumor lymphatic metastasis.
Xiao-Mei Yang, Hai-Xiong Han, Fei Sui, Yu-Min Dai, Ming Chen, Jian-Guo Geng. Biochem Biophys Res Commun 2010
Xiao-Mei Yang, Hai-Xiong Han, Fei Sui, Yu-Min Dai, Ming Chen, Jian-Guo Geng. Biochem Biophys Res Commun 2010
36
Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis.
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
Lukasz Huminiecki, Michael Gorn, Steven Suchting, Richard Poulsom, Roy Bicknell. Genomics 2002
19
Targeting Slit-Roundabout signaling inhibits tumor angiogenesis in chemical-induced squamous cell carcinogenesis.
Li-Jing Wang, Yuan Zhao, Bing Han, Yu-Guang Ma, Jie Zhang, Ding-Ming Yang, Jian-Wen Mao, Fu-Tian Tang, Wei-Dong Li, Yang Yang,[...]. Cancer Sci 2008
Li-Jing Wang, Yuan Zhao, Bing Han, Yu-Guang Ma, Jie Zhang, Ding-Ming Yang, Jian-Wen Mao, Fu-Tian Tang, Wei-Dong Li, Yang Yang,[...]. Cancer Sci 2008
28
Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B.
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
Alexander W Koch, Thomas Mathivet, Bruno Larrivée, Raymond K Tong, Joe Kowalski, Laurence Pibouin-Fragner, Karine Bouvrée, Scott Stawicki, Katrina Nicholes, Nisha Rathore,[...]. Dev Cell 2011
18
Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
Christopher A Jones, Naoyuki Nishiya, Nyall R London, Weiquan Zhu, Lise K Sorensen, Aubrey C Chan, Chinten J Lim, Haoyu Chen, Qisheng Zhang, Peter G Schultz,[...]. Nat Cell Biol 2009
18
Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis.
Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding,[...]. Cell Res 2011
Wei-Jie Zhou, Zhen H Geng, Shan Chi, Wenli Zhang, Xiao-Feng Niu, Shu-Jue Lan, Li Ma, Xuesong Yang, Li-Jing Wang, Yan-Qing Ding,[...]. Cell Res 2011
18
Repulsive axon guidance molecule Slit3 is a novel angiogenic factor.
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
Bing Zhang, Ursula M Dietrich, Jian-Guo Geng, Roy Bicknell, Jeffrey D Esko, Lianchun Wang. Blood 2009
17
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors.
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
Helen Sheldon, Maud Andre, John A Legg, Paul Heal, John M Herbert, Richard Sainson, Anshula S Sharma, Jan K Kitajewski, Victoria L Heath, Roy Bicknell. FASEB J 2009
17
Structural insights into the Slit-Robo complex.
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
Cecile Morlot, Nicole M Thielens, Raimond B G Ravelli, Wieger Hemrika, Roland A Romijn, Piet Gros, Stephen Cusack, Andrew A McCarthy. Proc Natl Acad Sci U S A 2007
15
Regulation of commissural axon pathfinding by slit and its Robo receptors.
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
Barry J Dickson, Giorgio F Gilestro. Annu Rev Cell Dev Biol 2006
14
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
K Wong, X R Ren, Y Z Huang, Y Xie, G Liu, H Saito, H Tang, L Wen, S M Brady-Kalnay, L Mei,[...]. Cell 2001
13
SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
Ashraf Dallol, Nancy Fernandes Da Silva, Paolo Viacava, John D Minna, Ivan Bieche, Eamonn R Maher, Farida Latif. Cancer Res 2002
12
Slit is the midline repellent for the robo receptor in Drosophila.
T Kidd, K S Bland, C S Goodman. Cell 1999
T Kidd, K S Bland, C S Goodman. Cell 1999
12
Vascular Robo4 restricts proangiogenic VEGF signaling in breast.
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
Rebecca Marlow, Mikhail Binnewies, Lise K Sorensen, Stefanie D Monica, Phyllis Strickland, E Camilla Forsberg, Dean Y Li, Lindsay Hinck. Proc Natl Acad Sci U S A 2010
19
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration.
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
Steven Suchting, Paul Heal, Kiki Tahtis, Lorna M Stewart, Roy Bicknell. FASEB J 2005
12
Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target.
Hirotaka Ito, Shin-ichi Funahashi, Naoko Yamauchi, Junji Shibahara, Yutaka Midorikawa, Shigeto Kawai, Yasuko Kinoshita, Akira Watanabe, Yoshitaka Hippo, Toshihiko Ohtomo,[...]. Clin Cancer Res 2006
Hirotaka Ito, Shin-ichi Funahashi, Naoko Yamauchi, Junji Shibahara, Yutaka Midorikawa, Shigeto Kawai, Yasuko Kinoshita, Akira Watanabe, Yoshitaka Hippo, Toshihiko Ohtomo,[...]. Clin Cancer Res 2006
16
MiR-218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor.
Jun Tie, Yanglin Pan, Lina Zhao, Kaichun Wu, Jie Liu, Shiren Sun, Xuegang Guo, Biaoluo Wang, Yi Gang, Yongguo Zhang,[...]. PLoS Genet 2010
Jun Tie, Yanglin Pan, Lina Zhao, Kaichun Wu, Jie Liu, Shiren Sun, Xuegang Guo, Biaoluo Wang, Yi Gang, Yongguo Zhang,[...]. PLoS Genet 2010
11
Potential anti-angiogenic role of Slit2 in corneal neovascularization.
Xi Han, Ming-Chang Zhang. Exp Eye Res 2010
Xi Han, Ming-Chang Zhang. Exp Eye Res 2010
50
Slits and Roundabouts in cancer, tumour angiogenesis and endothelial cell migration.
John A Legg, John M J Herbert, Patricia Clissold, Roy Bicknell. Angiogenesis 2008
John A Legg, John M J Herbert, Patricia Clissold, Roy Bicknell. Angiogenesis 2008
11
Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers.
R E Dickinson, A Dallol, I Bieche, D Krex, D Morton, E R Maher, F Latif. Br J Cancer 2004
R E Dickinson, A Dallol, I Bieche, D Krex, D Morton, E R Maher, F Latif. Br J Cancer 2004
11
Magic roundabout, a tumor endothelial marker: expression and signaling.
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
Pankaj Seth, Yanfeng Lin, Jun-ichi Hanai, Venkatesha Shivalingappa, Mabel P Duyao, Vikas P Sukhatme. Biochem Biophys Res Commun 2005
11
SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
Ruo-Chia Tseng, Shih-Hua Lee, Han-Shui Hsu, Ben-Han Chen, Wan-Ching Tsai, Ching Tzao, Yi-Ching Wang. Cancer Res 2010
11
Molecular mechanisms and clinical applications of angiogenesis.
Peter Carmeliet, Rakesh K Jain. Nature 2011
Peter Carmeliet, Rakesh K Jain. Nature 2011
10
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish.
Jason E Fish, Joshua D Wythe, Tong Xiao, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava, Stephanie Woo. Development 2011
Jason E Fish, Joshua D Wythe, Tong Xiao, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava, Stephanie Woo. Development 2011
10
MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.
Nehad M Alajez, Michelle Lenarduzzi, Emma Ito, Angela B Y Hui, Wei Shi, Jeff Bruce, Shijun Yue, Shao H Huang, Wei Xu, John Waldron,[...]. Cancer Res 2011
Nehad M Alajez, Michelle Lenarduzzi, Emma Ito, Angela B Y Hui, Wei Shi, Jeff Bruce, Shijun Yue, Shao H Huang, Wei Xu, John Waldron,[...]. Cancer Res 2011
10
The neuronal guidance cue Slit2 induces targeted migration and may play a role in brain metastasis of breast cancer cells.
Bernd C Schmid, Günther A Rezniczek, Gerhild Fabjani, Toshiyuki Yoneda, Sepp Leodolter, Robert Zeillinger. Breast Cancer Res Treat 2007
Bernd C Schmid, Günther A Rezniczek, Gerhild Fabjani, Toshiyuki Yoneda, Sepp Leodolter, Robert Zeillinger. Breast Cancer Res Treat 2007
13
Potential role of the Slit/Robo signal pathway in angiogenesis.
Masakazu Fujiwara, Mohammad Ghazizadeh, Oichi Kawanami. Vasc Med 2006
Masakazu Fujiwara, Mohammad Ghazizadeh, Oichi Kawanami. Vasc Med 2006
20
SLIT2 axon guidance molecule is frequently inactivated in colorectal cancer and suppresses growth of colorectal carcinoma cells.
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
Ashraf Dallol, Dion Morton, Eamonn R Maher, Farida Latif. Cancer Res 2003
9
Switching repulsion to attraction: changing responses to slit during transition in mesoderm migration.
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
S G Kramer, T Kidd, J H Simpson, C S Goodman. Science 2001
9
Slit2 involvement in glioma cell migration is mediated by Robo1 receptor.
Sonja Mertsch, Nicole Schmitz, Astrid Jeibmann, Jian-Guo Geng, Werner Paulus, Volker Senner. J Neurooncol 2008
Sonja Mertsch, Nicole Schmitz, Astrid Jeibmann, Jian-Guo Geng, Werner Paulus, Volker Senner. J Neurooncol 2008
9
SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
Uta Grieshammer, Le Ma, Andrew S Plump, Fan Wang, Marc Tessier-Lavigne, Gail R Martin. Dev Cell 2004
9
Slit2 Promotes Angiogenic Activity Via the Robo1-VEGFR2-ERK1/2 Pathway in Both In Vivo and In Vitro Studies.
Shanshan Li, Lvzhen Huang, Yaoyao Sun, Yujing Bai, Fei Yang, Wenzhen Yu, Fangting Li, Qi Zhang, Bin Wang, Jian-Guo Geng,[...]. Invest Ophthalmol Vis Sci 2015
Shanshan Li, Lvzhen Huang, Yaoyao Sun, Yujing Bai, Fei Yang, Wenzhen Yu, Fangting Li, Qi Zhang, Bin Wang, Jian-Guo Geng,[...]. Invest Ophthalmol Vis Sci 2015
33
Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons.
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
H S Li, J H Chen, W Wu, T Fagaly, L Zhou, W Yuan, S Dupuis, Z H Jiang, W Nash, C Gick,[...]. Cell 1999
8
Common mechanisms of nerve and blood vessel wiring.
Peter Carmeliet, Marc Tessier-Lavigne. Nature 2005
Peter Carmeliet, Marc Tessier-Lavigne. Nature 2005
8
Robo1/Robo4: differential expression of angiogenic markers in colorectal cancer.
Jörn Gröne, Oliver Doebler, Christoph Loddenkemper, Birgit Hotz, Heinz-Johannes Buhr, Sarah Bhargava. Oncol Rep 2006
Jörn Gröne, Oliver Doebler, Christoph Loddenkemper, Birgit Hotz, Heinz-Johannes Buhr, Sarah Bhargava. Oncol Rep 2006
13
Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein.
H Hu. Nat Neurosci 2001
H Hu. Nat Neurosci 2001
8
MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling.
Eric M Small, Lillian B Sutherland, Kartik N Rajagopalan, Shusheng Wang, Eric N Olson. Circ Res 2010
Eric M Small, Lillian B Sutherland, Kartik N Rajagopalan, Shusheng Wang, Eric N Olson. Circ Res 2010
8
Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic cancer.
Andreas Göhrig, Katharina M Detjen, Georg Hilfenhaus, Jan L Körner, Martina Welzel, Ruza Arsenic, Rosa Schmuck, Marcus Bahra, Jane Y Wu, Bertram Wiedenmann,[...]. Cancer Res 2014
Andreas Göhrig, Katharina M Detjen, Georg Hilfenhaus, Jan L Körner, Martina Welzel, Ruza Arsenic, Rosa Schmuck, Marcus Bahra, Jane Y Wu, Bertram Wiedenmann,[...]. Cancer Res 2014
12
Directional guidance of neuronal migration in the olfactory system by the protein Slit.
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
W Wu, K Wong, J Chen, Z Jiang, S Dupuis, J Y Wu, Y Rao. Nature 1999
8
Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells.
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
Anil Prasad, Aaron Z Fernandis, Yi Rao, Ramesh K Ganju. J Biol Chem 2004
8
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils.
Soumitra Tole, Ilya M Mukovozov, Yi-Wei Huang, Marco A O Magalhaes, Ming Yan, Min Rui Crow, Guang Ying Liu, Chun Xiang Sun, Yves Durocher, Michael Glogauer,[...]. J Leukoc Biol 2009
Soumitra Tole, Ilya M Mukovozov, Yi-Wei Huang, Marco A O Magalhaes, Ming Yan, Min Rui Crow, Guang Ying Liu, Chun Xiang Sun, Yves Durocher, Michael Glogauer,[...]. J Leukoc Biol 2009
12
Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
Helong Zhao, Appakkudal R Anand, Ramesh K Ganju. J Immunol 2014
13
Slit-2 induces a tumor-suppressive effect by regulating beta-catenin in breast cancer cells.
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
Anil Prasad, Vikram Paruchuri, Anju Preet, Farida Latif, Ramesh K Ganju. J Biol Chem 2008
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.