Kim Tieu, Celine Perier, Casper Caspersen, Peter Teismann, Du-Chu Wu, Shi-Du Yan, Ali Naini, Miquel Vila, Vernice Jackson-Lewis, Ravichandran Ramasamy, Serge Przedborski. J Clin Invest 2003
Times Cited: 296
Times Cited: 296
Times Cited
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Similarity
Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens,[...]. Science 2013
38
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
Yun-Hee Youm, Kim Y Nguyen, Ryan W Grant, Emily L Goldberg, Monica Bodogai, Dongin Kim, Dominic D'Agostino, Noah Planavsky, Christopher Lupfer, Thirumala D Kanneganti,[...]. Nat Med 2015
33
D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease.
Y Kashiwaya, T Takeshima, N Mori, K Nakashima, K Clarke, R L Veech. Proc Natl Acad Sci U S A 2000
Y Kashiwaya, T Takeshima, N Mori, K Nakashima, K Clarke, R L Veech. Proc Natl Acad Sci U S A 2000
31
Treatment of Parkinson disease with diet-induced hyperketonemia: a feasibility study.
T B Vanitallie, C Nonas, A Di Rocco, K Boyar, K Hyams, S B Heymsfield. Neurology 2005
T B Vanitallie, C Nonas, A Di Rocco, K Boyar, K Hyams, S B Heymsfield. Neurology 2005
30
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial.
Samuel T Henderson, Janet L Vogel, Linda J Barr, Fiona Garvin, Julie J Jones, Lauren C Costantini. Nutr Metab (Lond) 2009
Samuel T Henderson, Janet L Vogel, Linda J Barr, Fiona Garvin, Julie J Jones, Lauren C Costantini. Nutr Metab (Lond) 2009
23
22
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis.
Zhong Zhao, Dale J Lange, Andrei Voustianiouk, Donal MacGrogan, Lap Ho, Jason Suh, Nelson Humala, Meenakshisundaram Thiyagarajan, Jun Wang, Giulio M Pasinetti. BMC Neurosci 2006
Zhong Zhao, Dale J Lange, Andrei Voustianiouk, Donal MacGrogan, Lap Ho, Jason Suh, Nelson Humala, Meenakshisundaram Thiyagarajan, Jun Wang, Giulio M Pasinetti. BMC Neurosci 2006
21
Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics.
Patrycja Puchalska, Peter A Crawford. Cell Metab 2017
Patrycja Puchalska, Peter A Crawford. Cell Metab 2017
21
3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons.
Krisztina Marosi, Sang Woo Kim, Keelin Moehl, Morten Scheibye-Knudsen, Aiwu Cheng, Roy Cutler, Simonetta Camandola, Mark P Mattson. J Neurochem 2016
Krisztina Marosi, Sang Woo Kim, Keelin Moehl, Morten Scheibye-Knudsen, Aiwu Cheng, Roy Cutler, Simonetta Camandola, Mark P Mattson. J Neurochem 2016
20
β-Hydroxybutyrate in the Brain: One Molecule, Multiple Mechanisms.
Lavanya B Achanta, Caroline D Rae. Neurochem Res 2017
Lavanya B Achanta, Caroline D Rae. Neurochem Res 2017
20
Effects of beta-hydroxybutyrate on cognition in memory-impaired adults.
Mark A Reger, Samuel T Henderson, Cathy Hale, Brenna Cholerton, Laura D Baker, G S Watson, Karen Hyde, Darla Chapman, Suzanne Craft. Neurobiol Aging 2004
Mark A Reger, Samuel T Henderson, Cathy Hale, Brenna Cholerton, Laura D Baker, G S Watson, Karen Hyde, Darla Chapman, Suzanne Craft. Neurobiol Aging 2004
19
A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease.
Yoshihiro Kashiwaya, Christian Bergman, Jong-Hwan Lee, Ruiqian Wan, M Todd King, Mohamed R Mughal, Eitan Okun, Kieran Clarke, Mark P Mattson, Richard L Veech. Neurobiol Aging 2013
Yoshihiro Kashiwaya, Christian Bergman, Jong-Hwan Lee, Ruiqian Wan, M Todd King, Mohamed R Mughal, Eitan Okun, Kieran Clarke, Mark P Mattson, Richard L Veech. Neurobiol Aging 2013
19
Low-fat versus ketogenic diet in Parkinson's disease: A pilot randomized controlled trial.
Matthew C L Phillips, Deborah K J Murtagh, Linda J Gilbertson, Fredrik J S Asztely, Christopher D P Lynch. Mov Disord 2018
Matthew C L Phillips, Deborah K J Murtagh, Linda J Gilbertson, Fredrik J S Asztely, Christopher D P Lynch. Mov Disord 2018
19
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation.
M Maalouf, P G Sullivan, L Davis, D Y Kim, J M Rho. Neuroscience 2007
M Maalouf, P G Sullivan, L Davis, D Y Kim, J M Rho. Neuroscience 2007
18
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet.
Kristopher J Bough, Jonathon Wetherington, Bjørnar Hassel, Jean Francois Pare, Jeremy W Gawryluk, James G Greene, Renee Shaw, Yoland Smith, Jonathan D Geiger, Raymond J Dingledine. Ann Neurol 2006
Kristopher J Bough, Jonathon Wetherington, Bjørnar Hassel, Jean Francois Pare, Jeremy W Gawryluk, James G Greene, Renee Shaw, Yoland Smith, Jonathan D Geiger, Raymond J Dingledine. Ann Neurol 2006
17
The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.
Mahbubur Rahman, Sajjad Muhammad, Mahtab A Khan, Hui Chen, Dirk A Ridder, Helge Müller-Fielitz, Barbora Pokorná, Tillman Vollbrandt, Ines Stölting, Roger Nadrowitz,[...]. Nat Commun 2014
Mahbubur Rahman, Sajjad Muhammad, Mahtab A Khan, Hui Chen, Dirk A Ridder, Helge Müller-Fielitz, Barbora Pokorná, Tillman Vollbrandt, Ines Stölting, Roger Nadrowitz,[...]. Nat Commun 2014
17
The ketogenic diet as a treatment paradigm for diverse neurological disorders.
Carl E Stafstrom, Jong M Rho. Front Pharmacol 2012
Carl E Stafstrom, Jong M Rho. Front Pharmacol 2012
17
Neuroprotective and anti-inflammatory activities of ketogenic diet on MPTP-induced neurotoxicity.
Xinxin Yang, Baohua Cheng. J Mol Neurosci 2010
Xinxin Yang, Baohua Cheng. J Mol Neurosci 2010
17
Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects.
Kieran Clarke, Kirill Tchabanenko, Robert Pawlosky, Emma Carter, M Todd King, Kathy Musa-Veloso, Manki Ho, Ashley Roberts, Jeremy Robertson, Theodore B Vanitallie,[...]. Regul Toxicol Pharmacol 2012
Kieran Clarke, Kirill Tchabanenko, Robert Pawlosky, Emma Carter, M Todd King, Kathy Musa-Veloso, Manki Ho, Ashley Roberts, Jeremy Robertson, Theodore B Vanitallie,[...]. Regul Toxicol Pharmacol 2012
16
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies.
Marwan Maalouf, Jong M Rho, Mark P Mattson. Brain Res Rev 2009
Marwan Maalouf, Jong M Rho, Mark P Mattson. Brain Res Rev 2009
16
(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.
Andrew K P Taggart, Jukka Kero, Xiaodong Gan, Tian-Quan Cai, Kang Cheng, Marc Ippolito, Ning Ren, Rebecca Kaplan, Kenneth Wu, Tsuei-Ju Wu,[...]. J Biol Chem 2005
Andrew K P Taggart, Jukka Kero, Xiaodong Gan, Tian-Quan Cai, Kang Cheng, Marc Ippolito, Ning Ren, Rebecca Kaplan, Kenneth Wu, Tsuei-Ju Wu,[...]. J Biol Chem 2005
16
The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism.
Richard L Veech. Prostaglandins Leukot Essent Fatty Acids 2004
Richard L Veech. Prostaglandins Leukot Essent Fatty Acids 2004
16
Insulin, ketone bodies, and mitochondrial energy transduction.
K Sato, Y Kashiwaya, C A Keon, N Tsuchiya, M T King, G K Radda, B Chance, K Clarke, R L Veech. FASEB J 1995
K Sato, Y Kashiwaya, C A Keon, N Tsuchiya, M T King, G K Radda, B Chance, K Clarke, R L Veech. FASEB J 1995
15
A ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.
Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven, Samuel T Henderson. Nutr Metab (Lond) 2005
Ingrid Van der Auwera, Stefaan Wera, Fred Van Leuven, Samuel T Henderson. Nutr Metab (Lond) 2005
15
Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate.
Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan,[...]. Elife 2016
Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan,[...]. Elife 2016
14
Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets.
A Paoli, A Rubini, J S Volek, K A Grimaldi. Eur J Clin Nutr 2013
A Paoli, A Rubini, J S Volek, K A Grimaldi. Eur J Clin Nutr 2013
14
Dietary ketosis enhances memory in mild cognitive impairment.
Robert Krikorian, Marcelle D Shidler, Krista Dangelo, Sarah C Couch, Stephen C Benoit, Deborah J Clegg. Neurobiol Aging 2012
Robert Krikorian, Marcelle D Shidler, Krista Dangelo, Sarah C Couch, Stephen C Benoit, Deborah J Clegg. Neurobiol Aging 2012
14
On the Metabolism of Exogenous Ketones in Humans.
Brianna J Stubbs, Pete J Cox, Rhys D Evans, Peter Santer, Jack J Miller, Olivia K Faull, Snapper Magor-Elliott, Satoshi Hiyama, Matthew Stirling, Kieran Clarke. Front Physiol 2017
Brianna J Stubbs, Pete J Cox, Rhys D Evans, Peter Santer, Jack J Miller, Olivia K Faull, Snapper Magor-Elliott, Satoshi Hiyama, Matthew Stirling, Kieran Clarke. Front Physiol 2017
14
The ketogenic diet increases mitochondrial uncoupling protein levels and activity.
Patrick G Sullivan, Nancy A Rippy, Kristina Dorenbos, Rachele C Concepcion, Aakash K Agarwal, Jong M Rho. Ann Neurol 2004
Patrick G Sullivan, Nancy A Rippy, Kristina Dorenbos, Rachele C Concepcion, Aakash K Agarwal, Jong M Rho. Ann Neurol 2004
13
A new way to produce hyperketonemia: use of ketone ester in a case of Alzheimer's disease.
Mary T Newport, Theodore B VanItallie, Yoshihiro Kashiwaya, Michael Todd King, Richard L Veech. Alzheimers Dement 2015
Mary T Newport, Theodore B VanItallie, Yoshihiro Kashiwaya, Michael Todd King, Richard L Veech. Alzheimers Dement 2015
13
Ketogenic diet protects dopaminergic neurons against 6-OHDA neurotoxicity via up-regulating glutathione in a rat model of Parkinson's disease.
Baohua Cheng, Xinxin Yang, Liangxiang An, Bo Gao, Xia Liu, Shuwei Liu. Brain Res 2009
Baohua Cheng, Xinxin Yang, Liangxiang An, Bo Gao, Xia Liu, Shuwei Liu. Brain Res 2009
18
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.
Zhongyu Xie, Di Zhang, Dongjun Chung, Zhanyun Tang, He Huang, Lunzhi Dai, Shankang Qi, Jingya Li, Gozde Colak, Yue Chen,[...]. Mol Cell 2016
Zhongyu Xie, Di Zhang, Dongjun Chung, Zhanyun Tang, He Huang, Lunzhi Dai, Shankang Qi, Jingya Li, Gozde Colak, Yue Chen,[...]. Mol Cell 2016
13
Neuroprotective and disease-modifying effects of the ketogenic diet.
Maciej Gasior, Michael A Rogawski, Adam L Hartman. Behav Pharmacol 2006
Maciej Gasior, Michael A Rogawski, Adam L Hartman. Behav Pharmacol 2006
13
Ketone body metabolism and cardiovascular disease.
David G Cotter, Rebecca C Schugar, Peter A Crawford. Am J Physiol Heart Circ Physiol 2013
David G Cotter, Rebecca C Schugar, Peter A Crawford. Am J Physiol Heart Circ Physiol 2013
13
Role of Ketogenic Diets in Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).
Dariusz Włodarek. Nutrients 2019
Dariusz Włodarek. Nutrients 2019
13
β-hydroxybutyrate: much more than a metabolite.
John C Newman, Eric Verdin. Diabetes Res Clin Pract 2014
John C Newman, Eric Verdin. Diabetes Res Clin Pract 2014
12
Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease.
Wei Zhao, Merina Varghese, Prashant Vempati, Anastasiya Dzhun, Alice Cheng, Jun Wang, Dale Lange, Amanda Bilski, Irene Faravelli, Giulio Maria Pasinetti. PLoS One 2012
Wei Zhao, Merina Varghese, Prashant Vempati, Anastasiya Dzhun, Alice Cheng, Jun Wang, Dale Lange, Amanda Bilski, Irene Faravelli, Giulio Maria Pasinetti. PLoS One 2012
15
Ketone bodies mimic the life span extending properties of caloric restriction.
Richard L Veech, Patrick C Bradshaw, Kieran Clarke, William Curtis, Robert Pawlosky, M Todd King. IUBMB Life 2017
Richard L Veech, Patrick C Bradshaw, Kieran Clarke, William Curtis, Robert Pawlosky, M Todd King. IUBMB Life 2017
12
Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions.
María L Haces, Karla Hernández-Fonseca, Omar N Medina-Campos, Teresa Montiel, José Pedraza-Chaverri, Lourdes Massieu. Exp Neurol 2008
María L Haces, Karla Hernández-Fonseca, Omar N Medina-Campos, Teresa Montiel, José Pedraza-Chaverri, Lourdes Massieu. Exp Neurol 2008
12
Feasibility and efficacy data from a ketogenic diet intervention in Alzheimer's disease.
Matthew K Taylor, Debra K Sullivan, Jonathan D Mahnken, Jeffrey M Burns, Russell H Swerdlow. Alzheimers Dement (N Y) 2017
Matthew K Taylor, Debra K Sullivan, Jonathan D Mahnken, Jeffrey M Burns, Russell H Swerdlow. Alzheimers Dement (N Y) 2017
12
Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet.
Julie B Milder, Li-Ping Liang, Manisha Patel. Neurobiol Dis 2010
Julie B Milder, Li-Ping Liang, Manisha Patel. Neurobiol Dis 2010
11
Ketones block amyloid entry and improve cognition in an Alzheimer's model.
Jun Xiang Yin, Marwan Maalouf, Pengcheng Han, Minglei Zhao, Ming Gao, Turner Dharshaun, Christopher Ryan, Julian Whitelegge, Jie Wu, David Eisenberg,[...]. Neurobiol Aging 2016
Jun Xiang Yin, Marwan Maalouf, Pengcheng Han, Minglei Zhao, Ming Gao, Turner Dharshaun, Christopher Ryan, Julian Whitelegge, Jie Wu, David Eisenberg,[...]. Neurobiol Aging 2016
14
Ketone bodies are protective against oxidative stress in neocortical neurons.
Do Young Kim, Laurie M Davis, Patrick G Sullivan, Marwan Maalouf, Timothy A Simeone, Johannes van Brederode, Jong M Rho. J Neurochem 2007
Do Young Kim, Laurie M Davis, Patrick G Sullivan, Marwan Maalouf, Timothy A Simeone, Johannes van Brederode, Jong M Rho. J Neurochem 2007
11
The efficacy of the ketogenic diet on motor functions in Parkinson's disease: A rat model.
Sheida Shaafi, Safa Najmi, Hamed Aliasgharpour, Javad Mahmoudi, Saeed Sadigh-Etemad, Mahdi Farhoudi, Negar Baniasadi. Iran J Neurol 2016
Sheida Shaafi, Safa Najmi, Hamed Aliasgharpour, Javad Mahmoudi, Saeed Sadigh-Etemad, Mahdi Farhoudi, Negar Baniasadi. Iran J Neurol 2016
36
A ketogenic diet improves motor performance but does not affect β-amyloid levels in a mouse model of Alzheimer's disease.
Tina L Beckett, Christa M Studzinski, Jeffrey N Keller, M Paul Murphy, Dana M Niedowicz. Brain Res 2013
Tina L Beckett, Christa M Studzinski, Jeffrey N Keller, M Paul Murphy, Dana M Niedowicz. Brain Res 2013
20
Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats.
Shannon L Kesl, Angela M Poff, Nathan P Ward, Tina N Fiorelli, Csilla Ari, Ashley J Van Putten, Jacob W Sherwood, Patrick Arnold, Dominic P D'Agostino. Nutr Metab (Lond) 2016
Shannon L Kesl, Angela M Poff, Nathan P Ward, Tina N Fiorelli, Csilla Ari, Ashley J Van Putten, Jacob W Sherwood, Patrick Arnold, Dominic P D'Agostino. Nutr Metab (Lond) 2016
12
Anti-inflammatory effects of BHBA in both in vivo and in vitro Parkinson's disease models are mediated by GPR109A-dependent mechanisms.
Shou-Peng Fu, Jian-Fa Wang, Wen-Jing Xue, Hong-Mei Liu, Bing-run Liu, Ya-Long Zeng, Su-Nan Li, Bing-Xu Huang, Qing-Kang Lv, Wei Wang,[...]. J Neuroinflammation 2015
Shou-Peng Fu, Jian-Fa Wang, Wen-Jing Xue, Hong-Mei Liu, Bing-run Liu, Ya-Long Zeng, Su-Nan Li, Bing-Xu Huang, Qing-Kang Lv, Wei Wang,[...]. J Neuroinflammation 2015
11
Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group.
Eric H Kossoff, Beth A Zupec-Kania, Stéphane Auvin, Karen R Ballaban-Gil, A G Christina Bergqvist, Robyn Blackford, Jeffrey R Buchhalter, Roberto H Caraballo, J Helen Cross, Maria G Dahlin,[...]. Epilepsia Open 2018
Eric H Kossoff, Beth A Zupec-Kania, Stéphane Auvin, Karen R Ballaban-Gil, A G Christina Bergqvist, Robyn Blackford, Jeffrey R Buchhalter, Roberto H Caraballo, J Helen Cross, Maria G Dahlin,[...]. Epilepsia Open 2018
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.