A citation-based method for searching scientific literature

M Corral-Debrinski, T Horton, M T Lott, J M Shoffner, M F Beal, D C Wallace. Nat Genet 1992
Times Cited: 694







List of co-cited articles
1877 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
35

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging.
G C Kujoth, A Hiona, T D Pugh, S Someya, K Panzer, S E Wohlgemuth, T Hofer, A Y Seo, R Sullivan, W A Jobling,[...]. Science 2005
30

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease.
Andreas Bender, Kim J Krishnan, Christopher M Morris, Geoffrey A Taylor, Amy K Reeve, Robert H Perry, Evelyn Jaros, Joshua S Hersheson, Joanne Betts, Thomas Klopstock,[...]. Nat Genet 2006
28

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons.
Yevgenya Kraytsberg, Elena Kudryavtseva, Ann C McKee, Changiz Geula, Neil W Kowall, Konstantin Khrapko. Nat Genet 2006
637
23

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
21



High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain.
Michael T Lin, David K Simon, Colette H Ahn, Lauren M Kim, M Flint Beal. Hum Mol Genet 2002
250
17

The biologic clock: the mitochondria?
D Harman. J Am Geriatr Soc 1972
16


Marked changes in mitochondrial DNA deletion levels in Alzheimer brains.
M Corral-Debrinski, T Horton, M T Lott, J M Shoffner, A C McKee, M F Beal, B H Graham, D C Wallace. Genomics 1994
234
15

Sequence and organization of the human mitochondrial genome.
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
15



Mitochondrial DNA-deletion mutations accumulate intracellularly to detrimental levels in aged human skeletal muscle fibers.
Entela Bua, Jody Johnson, Allen Herbst, Bridget Delong, Debbie McKenzie, Shahriar Salamat, Judd M Aiken. Am J Hum Genet 2006
288
13

Decline in skeletal muscle mitochondrial function with aging in humans.
Kevin R Short, Maureen L Bigelow, Jane Kahl, Ravinder Singh, Jill Coenen-Schimke, Sreekumar Raghavakaimal, K Sreekumaran Nair. Proc Natl Acad Sci U S A 2005
759
13

What causes mitochondrial DNA deletions in human cells?
Kim J Krishnan, Amy K Reeve, David C Samuels, Patrick F Chinnery, John K Blackwood, Robert W Taylor, Sjoerd Wanrooij, Johannes N Spelbrink, Robert N Lightowlers, Doug M Turnbull. Nat Genet 2008
274
13

Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain.
N W Soong, D R Hinton, G Cortopassi, N Arnheim. Nat Genet 1992
347
13

Mitochondrial point mutations do not limit the natural lifespan of mice.
Marc Vermulst, Jason H Bielas, Gregory C Kujoth, Warren C Ladiges, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2007
282
12

Ageing muscle: clonal expansions of mitochondrial DNA point mutations and deletions cause focal impairment of mitochondrial function.
Guillemette Fayet, Monica Jansson, Damien Sternberg, Ali Reza Moslemi, Patricia Blondy, Anne Lombès, Michel Fardeau, Anders Oldfors. Neuromuscul Disord 2002
134
12

The Mitochondrial Basis of Aging.
Nuo Sun, Richard J Youle, Toren Finkel. Mol Cell 2016
610
12

DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
Marc Vermulst, Jonathan Wanagat, Gregory C Kujoth, Jason H Bielas, Peter S Rabinovitch, Tomas A Prolla, Lawrence A Loeb. Nat Genet 2008
278
11


Extension of murine life span by overexpression of catalase targeted to mitochondria.
Samuel E Schriner, Nancy J Linford, George M Martin, Piper Treuting, Charles E Ogburn, Mary Emond, Pinar E Coskun, Warren Ladiges, Norman Wolf, Holly Van Remmen,[...]. Science 2005
11


Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication.
Y Michikawa, F Mazzucchelli, N Bresolin, G Scarlato, G Attardi. Science 1999
537
10

Targeted enrichment and high-resolution digital profiling of mitochondrial DNA deletions in human brain.
Sean D Taylor, Nolan G Ericson, Joshua N Burton, Tomas A Prolla, John R Silber, Jay Shendure, Jason H Bielas. Aging Cell 2014
47
21

Universal heteroplasmy of human mitochondrial DNA.
Brendan A I Payne, Ian J Wilson, Patrick Yu-Wai-Man, Jonathan Coxhead, David Deehan, Rita Horvath, Robert W Taylor, David C Samuels, Mauro Santibanez-Koref, Patrick F Chinnery. Hum Mol Genet 2013
244
10

Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons.
Anne Grünewald, Karolina A Rygiel, Philippa D Hepplewhite, Christopher M Morris, Martin Picard, Doug M Turnbull. Ann Neurol 2016
132
10

Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease.
Christian Dölle, Irene Flønes, Gonzalo S Nido, Hrvoje Miletic, Nelson Osuagwu, Stine Kristoffersen, Peer K Lilleng, Jan Petter Larsen, Ole-Bjørn Tysnes, Kristoffer Haugarvoll,[...]. Nat Commun 2016
128
10


Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production.
Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T Rovio, Eric Dufour, Ivan Khvorostov, Johannes N Spelbrink, Rolf Wibom, Howard T Jacobs, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2005
387
9

Ageing-associated 5 kb deletion in human liver mitochondrial DNA.
T C Yen, J H Su, K L King, Y H Wei. Biochem Biophys Res Commun 1991
217
9

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.
G A Cortopassi, D Shibata, N W Soong, N Arnheim. Proc Natl Acad Sci U S A 1992
519
9

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
975
9


Mammalian Mitochondria and Aging: An Update.
Timo E S Kauppila, Johanna H K Kauppila, Nils-Göran Larsson. Cell Metab 2017
282
9

Hereditary early-onset Parkinson's disease caused by mutations in PINK1.
Enza Maria Valente, Patrick M Abou-Sleiman, Viviana Caputo, Miratul M K Muqit, Kirsten Harvey, Suzana Gispert, Zeeshan Ali, Domenico Del Turco, Anna Rita Bentivoglio, Daniel G Healy,[...]. Science 2004
9

Somatic progenitor cell vulnerability to mitochondrial DNA mutagenesis underlies progeroid phenotypes in Polg mutator mice.
Kati J Ahlqvist, Riikka H Hämäläinen, Shuichi Yatsuga, Marko Uutela, Mügen Terzioglu, Alexandra Götz, Saara Forsström, Petri Salven, Alexandre Angers-Loustau, Outi H Kopra,[...]. Cell Metab 2012
172
8

Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice.
Daniel Edgar, Irina Shabalina, Yolanda Camara, Anna Wredenberg, Maria Antonietta Calvaruso, Leo Nijtmans, Jan Nedergaard, Barbara Cannon, Nils-Göran Larsson, Aleksandra Trifunovic. Cell Metab 2009
152
8


Mitochondrial threshold effects.
Rodrigue Rossignol, Benjamin Faustin, Christophe Rocher, Monique Malgat, Jean-Pierre Mazat, Thierry Letellier. Biochem J 2003
486
8

Germline mitochondrial DNA mutations aggravate ageing and can impair brain development.
Jaime M Ross, James B Stewart, Erik Hagström, Stefan Brené, Arnaud Mourier, Giuseppe Coppotelli, Christoph Freyer, Marie Lagouge, Barry J Hoffer, Lars Olson,[...]. Nature 2013
181
8

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.
P Mecocci, U MacGarvey, A E Kaufman, D Koontz, J M Shoffner, D C Wallace, M F Beal. Ann Neurol 1993
574
8

Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions.
Andreas Bender, Rachel-Maria Schwarzkopf, Anja McMillan, Kim J Krishnan, Gabriele Rieder, Manuela Neumann, Matthias Elstner, Douglas M Turnbull, Thomas Klopstock. J Neurol 2008
66
12


Mitochondrial DNA genetics and the heteroplasmy conundrum in evolution and disease.
Douglas C Wallace, Dimitra Chalkia. Cold Spring Harb Perspect Biol 2013
356
8

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy.
D C Wallace, G Singh, M T Lott, J A Hodge, T G Schurr, A M Lezza, L J Elsas, E K Nikoskelainen. Science 1988
8

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
T Kitada, S Asakawa, N Hattori, H Matsumine, Y Yamamura, S Minoshima, M Yokochi, Y Mizuno, N Shimizu. Nature 1998
8

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Johanna H K Kauppila, Nina A Bonekamp, Arnaud Mourier, Marita A Isokallio, Alexandra Just, Timo E S Kauppila, James B Stewart, Nils-Göran Larsson. Nucleic Acids Res 2018
38
21


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.