A citation-based method for searching scientific literature

M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
Times Cited: 497







List of co-cited articles
1028 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
296
65

Guanylyl cyclase is a heat-stable enterotoxin receptor.
S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
527
46

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, Scott A Waldman. J Clin Invest 2011
99
30


Familial diarrhea syndrome caused by an activating GUCY2C mutation.
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
121
23

Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
170
22


Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion.
E A Mann, M L Jump, J Wu, E Yee, R A Giannella. Biochem Biophys Res Commun 1997
106
21

Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
126
20

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Shalina Mahajan-Miklos, Christine M Pierce, Robert M Solinga, Li Jing Sun,[...]. Eur J Pharmacol 2010
144
20

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
Peng Li, Jieru E Lin, Inna Chervoneva, Stephanie Schulz, Scott A Waldman, Giovanni M Pitari. Am J Pathol 2007
86
22

Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C.
Hila Romi, Idan Cohen, Daniella Landau, Suliman Alkrinawi, Baruch Yerushalmi, Reli Hershkovitz, Nitza Newman-Heiman, Garry R Cutting, Rivka Ofir, Sara Sivan,[...]. Am J Hum Genet 2012
58
32

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman. Gastroenterology 2010
80
22

Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.
Kris A Steinbrecher, Steve A Wowk, Jeffrey A Rudolph, David P Witte, Mitchell B Cohen. Am J Pathol 2002
84
21

Characterization of human uroguanylin: a member of the guanylin peptide family.
T Kita, C E Smith, K F Fok, K L Duffin, W M Moore, P J Karabatsos, J F Kachur, F K Hamra, N V Pidhorodeckyj, L R Forte. Am J Physiol 1994
118
18

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Peng Li, Stephanie Schulz, Alessandro Bombonati, Juan P Palazzo, Terry M Hyslop, Yihuan Xu, Amy A Baran, Linda D Siracusa, Giovanni M Pitari, Scott A Waldman. Gastroenterology 2007
101
16

Guanylyl cyclases and signaling by cyclic GMP.
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
907
16

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Christine M Pierce, Robert M Solinga, Jenny V Tobin, Shalina Mahajan-Miklos,[...]. Life Sci 2010
120
16

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity.
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
95
16

Two randomized trials of linaclotide for chronic constipation.
Anthony J Lembo, Harvey A Schneier, Steven J Shiff, Caroline B Kurtz, James E MacDougall, Xinwei D Jia, James Z Shao, Bernard J Lavins, Mark G Currie, Donald A Fitch,[...]. N Engl J Med 2011
218
16

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
William D Chey, Anthony J Lembo, Bernard J Lavins, Steven J Shiff, Caroline B Kurtz, Mark G Currie, James E MacDougall, Xinwei D Jia, James Z Shao, Donald A Fitch,[...]. Am J Gastroenterol 2012
268
16

Expression of guanylin is downregulated in mouse and human intestinal adenomas.
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
66
22

Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor.
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
71
21

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.
John N Lorenz, Michelle Nieman, Jenine Sabo, L Philip Sanford, Jennifer A Hawkins, Noeet Elitsur, Lara R Gawenis, Lane L Clarke, Mitchell B Cohen. J Clin Invest 2003
74
20

Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.
Xiaonan Han, Elizabeth Mann, Shila Gilbert, Yanfang Guan, Kris A Steinbrecher, Marshall H Montrose, Mitchell B Cohen. PLoS One 2011
61
24

Precursor structure, expression, and tissue distribution of human guanylin.
F J de Sauvage, S Keshav, W J Kuang, N Gillett, W Henzel, D V Goeddel. Proc Natl Acad Sci U S A 1992
140
14

Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
A C Chao, F J de Sauvage, Y J Dong, J A Wagner, D V Goeddel, P Gardner. EMBO J 1994
213
14


A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.
Satish Rao, Anthony J Lembo, Steven J Shiff, Bernard J Lavins, Mark G Currie, Xinwei D Jia, Kelvin Shi, James E MacDougall, James Z Shao, Paul Eng,[...]. Am J Gastroenterol 2012
243
14

Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Jieru E Lin, Francheska Colon-Gonzalez, Erik Blomain, Gilbert W Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E Snook, Tingting Zhan, Terry M Hyslop,[...]. Cancer Res 2016
38
36

Bacterial enterotoxins are associated with resistance to colon cancer.
G M Pitari, L V Zingman, D M Hodgson, A E Alekseev, S Kazerounian, M Bienengraeber, G Hajnóczky, A Terzic, S A Waldman. Proc Natl Acad Sci U S A 2003
116
13

Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
349
13

Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation.
Jeffrey M Johnston, Caroline B Kurtz, James E Macdougall, Bernard J Lavins, Mark G Currie, Donald A Fitch, Chris O'Dea, Mollie Baird, Anthony J Lembo. Gastroenterology 2010
159
13


Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.
Rong Gong, Cheng Ding, Ji Hu, Yao Lu, Fei Liu, Elizabeth Mann, Fuqiang Xu, Mitchell B Cohen, Minmin Luo. Science 2011
72
18

Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues.
S L Carrithers, M T Barber, S Biswas, S J Parkinson, P K Park, S D Goldstein, S A Waldman. Proc Natl Acad Sci U S A 1996
178
12

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.
H Eutamene, S Bradesi, M Larauche, V Theodorou, C Beaufrand, G Ohning, J Fioramonti, M Cohen, A P Bryant, C Kurtz,[...]. Neurogastroenterol Motil 2010
133
12

Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
73
16


GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz,[...]. PLoS One 2012
59
20

Cellular effects of guanylin and uroguanylin.
Aleksandra Sindić, Eberhard Schlatter. J Am Soc Nephrol 2006
53
20

Receptor guanylyl cyclase C (GC-C): regulation and signal transduction.
Nirmalya Basu, Najla Arshad, Sandhya S Visweswariah. Mol Cell Biochem 2010
44
25

Circulating prouroguanylin is processed to its active natriuretic form exclusively within the renal tubules.
Xun Qian, Nicholas G Moss, Robert C Fellner, Michael F Goy. Endocrinology 2008
28
39


Prouroguanylin and proguanylin: purification from colon, structure, and modulation of bioactivity by proteases.
F K Hamra, X Fan, W J Krause, R H Freeman, D T Chin, C E Smith, M G Currie, L R Forte. Endocrinology 1996
72
15




Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Joel Castro, Andrea M Harrington, Patrick A Hughes, Christopher M Martin, Pei Ge, Courtney M Shea, Hong Jin, Sarah Jacobson, Gerhard Hannig, Elizabeth Mann,[...]. Gastroenterology 2013
163
11

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer.
Chantell Wilson, Jieru E Lin, Peng Li, Adam E Snook, Jianping Gong, Takahiro Sato, Chengbao Liu, Melanie A Girondo, Hallgeir Rui, Terry Hyslop,[...]. Cancer Epidemiol Biomarkers Prev 2014
34
32


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.