A citation-based method for searching scientific literature

J D Rothstein, L J Martin, R W Kuncl. N Engl J Med 1992
Times Cited: 999







List of co-cited articles
1655 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
J D Rothstein, M Van Kammen, A I Levey, L J Martin, R W Kuncl. Ann Neurol 1995
34

Glutamate uptake.
N C Danbolt. Prog Neurobiol 2001
22

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1.
K Tanaka, K Watase, T Manabe, K Yamada, M Watanabe, K Takahashi, H Iwama, T Nishikawa, N Ichihara, T Kikuchi,[...]. Science 1997
20

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Manuela Neumann, Deepak M Sampathu, Linda K Kwong, Adam C Truax, Matthew C Micsenyi, Thomas T Chou, Jennifer Bruce, Theresa Schuck, Murray Grossman, Christopher M Clark,[...]. Science 2006
19

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis.
D R Rosen, T Siddique, D Patterson, D A Figlewicz, P Sapp, A Hentati, D Donaldson, J Goto, J P O'Regan, H X Deng. Nature 1993
18

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS.
Mariely DeJesus-Hernandez, Ian R Mackenzie, Bradley F Boeve, Adam L Boxer, Matt Baker, Nicola J Rutherford, Alexandra M Nicholson, NiCole A Finch, Heather Flynn, Jennifer Adamson,[...]. Neuron 2011
16

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).
David S Howland, Jian Liu, Yijin She, Beth Goad, Nicholas J Maragakis, Benjamin Kim, Jamie Erickson, John Kulik, Lisa DeVito, George Psaltis,[...]. Proc Natl Acad Sci U S A 2002
632
16

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis.
J D Rothstein, G Tsai, R W Kuncl, L Clawson, D R Cornblath, D B Drachman, A Pestronk, B L Stauch, J T Coyle. Ann Neurol 1990
533
15

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons.
Makiko Nagai, Diane B Re, Tetsuya Nagata, Alcmène Chalazonitis, Thomas M Jessell, Hynek Wichterle, Serge Przedborski. Nat Neurosci 2007
870
14

Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
13


Cloning and expression of a rat brain L-glutamate transporter.
G Pines, N C Danbolt, M Bjørås, Y Zhang, A Bendahan, L Eide, H Koepsell, J Storm-Mathisen, E Seeberg, B I Kanner. Nature 1992
13

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons.
Amanda M Haidet-Phillips, Mark E Hester, Carlos J Miranda, Kathrin Meyer, Lyndsey Braun, Ashley Frakes, SungWon Song, Shibi Likhite, Matthew J Murtha, Kevin D Foust,[...]. Nat Biotechnol 2011
541
12

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD.
Alan E Renton, Elisa Majounie, Adrian Waite, Javier Simón-Sánchez, Sara Rollinson, J Raphael Gibbs, Jennifer C Schymick, Hannu Laaksovirta, John C van Swieten, Liisa Myllykangas,[...]. Neuron 2011
12

Decoding ALS: from genes to mechanism.
J Paul Taylor, Robert H Brown, Don W Cleveland. Nature 2016
12

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.
Jeffrey D Rothstein, Sarjubhai Patel, Melissa R Regan, Christine Haenggeli, Yanhua H Huang, Dwight E Bergles, Lin Jin, Margaret Dykes Hoberg, Svetlana Vidensky, Dorothy S Chung,[...]. Nature 2005
12

The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.
L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht. Biochim Biophys Acta 2006
331
12


TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Tetsuaki Arai, Masato Hasegawa, Haruhiko Akiyama, Kenji Ikeda, Takashi Nonaka, Hiroshi Mori, David Mann, Kuniaki Tsuchiya, Mari Yoshida, Yoshio Hashizume,[...]. Biochem Biophys Res Commun 2006
10

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
M E Gurney, H Pu, A Y Chiu, M C Dal Canto, C Y Polchow, D D Alexander, J Caliendo, A Hentati, Y W Kwon, H X Deng. Science 1994
10

Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients.
Odile Spreux-Varoquaux, Gilbert Bensimon, Lucette Lacomblez, François Salachas, Pierre François Pradat, Nadine Le Forestier, Abdellatif Marouan, Michel Dib, Vincent Meininger. J Neurol Sci 2002
193
10

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
Brian J Wainger, Evangelos Kiskinis, Cassidy Mellin, Ole Wiskow, Steve S W Han, Jackson Sandoe, Numa P Perez, Luis A Williams, Seungkyu Lee, Gabriella Boulting,[...]. Cell Rep 2014
401
10

Alterations in expression of glutamatergic transporters and receptors in sporadic Alzheimer's disease.
C P Jacob, E Koutsilieri, J Bartl, E Neuen-Jacob, T Arzberger, N Zander, R Ravid, W Roggendorf, P Riederer, E Grünblatt. J Alzheimers Dis 2007
207
10

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate.
J D Rothstein, M Dykes-Hoberg, C A Pardo, L A Bristol, L Jin, R W Kuncl, Y Kanai, M A Hediger, Y Wang, J P Schielke,[...]. Neuron 1996
10

Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes.
Geraldine T Petr, Yan Sun, Natalie M Frederick, Yun Zhou, Sameer C Dhamne, Mustafa Q Hameed, Clive Miranda, Edward A Bedoya, Kathryn D Fischer, Wencke Armsen,[...]. J Neurosci 2015
191
10

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis.
Koji Yamanaka, Seung Joo Chun, Severine Boillee, Noriko Fujimori-Tonou, Hirofumi Yamashita, David H Gutmann, Ryosuke Takahashi, Hidemi Misawa, Don W Cleveland. Nat Neurosci 2008
803
9

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis.
Laura Ferraiuolo, Janine Kirby, Andrew J Grierson, Michael Sendtner, Pamela J Shaw. Nat Rev Neurol 2011
406
9


Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice.
Hong Guo, Liching Lai, Matthew E R Butchbach, Michael P Stockinger, Xiu Shan, Georgia A Bishop, Chien-liang Glenn Lin. Hum Mol Genet 2003
184
9

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.
L I Bruijn, M W Becher, M K Lee, K L Anderson, N A Jenkins, N G Copeland, S S Sisodia, J D Rothstein, D R Borchelt, D L Price,[...]. Neuron 1997
9

Loss of the astrocyte glutamate transporter GLT1 modifies disease in SOD1(G93A) mice.
Andrea C Pardo, Victor Wong, Leah M Benson, Margaret Dykes, Kohichi Tanaka, Jeffrey D Rothstein, Nicholas J Maragakis. Exp Neurol 2006
81
11

Structure of a glutamate transporter homologue from Pyrococcus horikoshii.
Dinesh Yernool, Olga Boudker, Yan Jin, Eric Gouaux. Nature 2004
611
9

Flux coupling in a neuronal glutamate transporter.
N Zerangue, M P Kavanaugh. Nature 1996
658
9

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man.
Lindsey R Fischer, Deborah G Culver, Philip Tennant, Albert A Davis, Minsheng Wang, Amilcar Castellano-Sanchez, Jaffar Khan, Meraida A Polak, Jonathan D Glass. Exp Neurol 2004
945
9

Localization of neuronal and glial glutamate transporters.
J D Rothstein, L Martin, A I Levey, M Dykes-Hoberg, L Jin, D Wu, N Nash, R W Kuncl. Neuron 1994
9


Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease.
Matthew R Hynd, Heather L Scott, Peter R Dodd. Neurochem Int 2004
594
9

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.
Bhuvaneish T Selvaraj, Matthew R Livesey, Chen Zhao, Jenna M Gregory, Owain T James, Elaine M Cleary, Amit K Chouhan, Angus B Gane, Emma M Perkins, Owen Dando,[...]. Nat Commun 2018
104
9


Exome sequencing reveals VCP mutations as a cause of familial ALS.
Janel O Johnson, Jessica Mandrioli, Michael Benatar, Yevgeniya Abramzon, Vivianna M Van Deerlin, John Q Trojanowski, J Raphael Gibbs, Maura Brunetti, Susan Gronka, Joanne Wuu,[...]. Neuron 2010
889
8

Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
A M Clement, M D Nguyen, E A Roberts, M L Garcia, S Boillée, M Rule, A P McMahon, W Doucette, D Siwek, R J Ferrante,[...]. Science 2003
811
8

Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion.
Dhruv Sareen, Jacqueline G O'Rourke, Pratap Meera, A K M G Muhammad, Sharday Grant, Megan Simpkinson, Shaughn Bell, Sharon Carmona, Loren Ornelas, Anais Sahabian,[...]. Sci Transl Med 2013
473
8

Amyotrophic lateral sclerosis.
Matthew C Kiernan, Steve Vucic, Benjamin C Cheah, Martin R Turner, Andrew Eisen, Orla Hardiman, James R Burrell, Margaret C Zoing. Lancet 2011
8



Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease.
E Masliah, M Alford, R DeTeresa, M Mallory, L Hansen. Ann Neurol 1996
340
8

Glutamate transporter alterations in Alzheimer disease are possibly associated with abnormal APP expression.
S Li, M Mallory, M Alford, S Tanaka, E Masliah. J Neuropathol Exp Neurol 1997
263
8



Positive and negative regulation of EAAT2 by NF-kappaB: a role for N-myc in TNFalpha-controlled repression.
Raquel Sitcheran, Pankaj Gupta, Paul B Fisher, Albert S Baldwin. EMBO J 2005
171
8


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.