Luika A Timmerman, Joaquín Grego-Bessa, Angel Raya, Esther Bertrán, José María Pérez-Pomares, Juan Díez, Sergi Aranda, Sergio Palomo, Frank McCormick, Juan Carlos Izpisúa-Belmonte, José Luis de la Pompa. Genes Dev 2004
Times Cited: 671
Times Cited: 671
Times Cited
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Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.
Luis Luna-Zurita, Belén Prados, Joaquim Grego-Bessa, Guillermo Luxán, Gonzalo del Monte, Alberto Benguría, Ralf H Adams, José María Pérez-Pomares, José Luis de la Pompa. J Clin Invest 2010
Luis Luna-Zurita, Belén Prados, Joaquim Grego-Bessa, Guillermo Luxán, Gonzalo del Monte, Alberto Benguría, Ralf H Adams, José María Pérez-Pomares, José Luis de la Pompa. J Clin Invest 2010
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Epithelial-mesenchymal transitions in development and disease.
Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto. Cell 2009
Jean Paul Thiery, Hervé Acloque, Ruby Y J Huang, M Angela Nieto. Cell 2009
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Molecular mechanisms of epithelial-mesenchymal transition.
Samy Lamouille, Jian Xu, Rik Derynck. Nat Rev Mol Cell Biol 2014
Samy Lamouille, Jian Xu, Rik Derynck. Nat Rev Mol Cell Biol 2014
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13
Mutations in NOTCH1 cause aortic valve disease.
Vidu Garg, Alecia N Muth, Joshua F Ransom, Marie K Schluterman, Robert Barnes, Isabelle N King, Paul D Grossfeld, Deepak Srivastava. Nature 2005
Vidu Garg, Alecia N Muth, Joshua F Ransom, Marie K Schluterman, Robert Barnes, Isabelle N King, Paul D Grossfeld, Deepak Srivastava. Nature 2005
13
Slug is a direct Notch target required for initiation of cardiac cushion cellularization.
Kyle Niessen, YangXin Fu, Linda Chang, Pamela A Hoodless, Deborah McFadden, Aly Karsan. J Cell Biol 2008
Kyle Niessen, YangXin Fu, Linda Chang, Pamela A Hoodless, Deborah McFadden, Aly Karsan. J Cell Biol 2008
13
The Wnt/beta-catenin pathway regulates cardiac valve formation.
Adam F L Hurlstone, Anna-Pavlina G Haramis, Erno Wienholds, Harry Begthel, Jeroen Korving, Fredericus Van Eeden, Edwin Cuppen, Danica Zivkovic, Ronald H A Plasterk, Hans Clevers. Nature 2003
Adam F L Hurlstone, Anna-Pavlina G Haramis, Erno Wienholds, Harry Begthel, Jeroen Korving, Fredericus Van Eeden, Edwin Cuppen, Danica Zivkovic, Ronald H A Plasterk, Hans Clevers. Nature 2003
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Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition.
Jiri Zavadil, Lukas Cermak, Noemi Soto-Nieves, Erwin P Böttinger. EMBO J 2004
Jiri Zavadil, Lukas Cermak, Noemi Soto-Nieves, Erwin P Böttinger. EMBO J 2004
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Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.
Bingruo Wu, Yidong Wang, Wendy Lui, Melissa Langworthy, Kevin L Tompkins, Antonis K Hatzopoulos, H Scott Baldwin, Bin Zhou. Circ Res 2011
Bingruo Wu, Yidong Wang, Wendy Lui, Melissa Langworthy, Kevin L Tompkins, Antonis K Hatzopoulos, H Scott Baldwin, Bin Zhou. Circ Res 2011
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Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development.
Dimitris Beis, Thomas Bartman, Suk-Won Jin, Ian C Scott, Leonard A D'Amico, Elke A Ober, Heather Verkade, Julie Frantsve, Holly A Field, Ann Wehman,[...]. Development 2005
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Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning.
Lijiang Ma, Mei-Fang Lu, Robert J Schwartz, James F Martin. Development 2005
Lijiang Ma, Mei-Fang Lu, Robert J Schwartz, James F Martin. Development 2005
11
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Sendurai A Mani, Wenjun Guo, Mai-Jing Liao, Elinor Ng Eaton, Ayyakkannu Ayyanan, Alicia Y Zhou, Mary Brooks, Ferenc Reinhard, Cheng Cheng Zhang, Michail Shipitsin,[...]. Cell 2008
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Endocardial to myocardial notch-wnt-bmp axis regulates early heart valve development.
Yidong Wang, Bingruo Wu, Alyssa A Chamberlain, Wendy Lui, Pratistha Koirala, Katalin Susztak, Diana Klein, Verdon Taylor, Bin Zhou. PLoS One 2013
Yidong Wang, Bingruo Wu, Alyssa A Chamberlain, Wendy Lui, Pratistha Koirala, Katalin Susztak, Diana Klein, Verdon Taylor, Bin Zhou. PLoS One 2013
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The basics of epithelial-mesenchymal transition.
Raghu Kalluri, Robert A Weinberg. J Clin Invest 2009
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Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis.
Donal MacGrogan, Gaetano D'Amato, Stanislao Travisano, Beatriz Martinez-Poveda, Guillermo Luxán, Gonzalo Del Monte-Nieto, Tania Papoutsi, Mauro Sbroggio, Vanesa Bou, Pablo Gomez-Del Arco,[...]. Circ Res 2016
Donal MacGrogan, Gaetano D'Amato, Stanislao Travisano, Beatriz Martinez-Poveda, Guillermo Luxán, Gonzalo Del Monte-Nieto, Tania Papoutsi, Mauro Sbroggio, Vanesa Bou, Pablo Gomez-Del Arco,[...]. Circ Res 2016
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Notch signaling is essential for ventricular chamber development.
Joaquín Grego-Bessa, Luis Luna-Zurita, Gonzalo del Monte, Victoria Bolós, Pedro Melgar, Alejandro Arandilla, Alistair N Garratt, Heesuk Zang, Yoh-Suke Mukouyama, Hanying Chen,[...]. Dev Cell 2007
Joaquín Grego-Bessa, Luis Luna-Zurita, Gonzalo del Monte, Victoria Bolós, Pedro Melgar, Alejandro Arandilla, Alistair N Garratt, Heesuk Zang, Yoh-Suke Mukouyama, Hanying Chen,[...]. Dev Cell 2007
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Notch signaling mediates hypoxia-induced tumor cell migration and invasion.
Cecilia Sahlgren, Maria V Gustafsson, Shaobo Jin, Lorenz Poellinger, Urban Lendahl. Proc Natl Acad Sci U S A 2008
Cecilia Sahlgren, Maria V Gustafsson, Shaobo Jin, Lorenz Poellinger, Urban Lendahl. Proc Natl Acad Sci U S A 2008
10
Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse.
Stefan Liebner, Anna Cattelino, Radiosa Gallini, Noemi Rudini, Monica Iurlaro, Stefano Piccolo, Elisabetta Dejana. J Cell Biol 2004
Stefan Liebner, Anna Cattelino, Radiosa Gallini, Noemi Rudini, Monica Iurlaro, Stefano Piccolo, Elisabetta Dejana. J Cell Biol 2004
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New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer.
Anushka Dongre, Robert A Weinberg. Nat Rev Mol Cell Biol 2019
Anushka Dongre, Robert A Weinberg. Nat Rev Mol Cell Biol 2019
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Notch Signaling in Development, Tissue Homeostasis, and Disease.
Chris Siebel, Urban Lendahl. Physiol Rev 2017
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10
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.
Kevin G Leong, Kyle Niessen, Iva Kulic, Afshin Raouf, Connie Eaves, Ingrid Pollet, Aly Karsan. J Exp Med 2007
Kevin G Leong, Kyle Niessen, Iva Kulic, Afshin Raouf, Connie Eaves, Ingrid Pollet, Aly Karsan. J Exp Med 2007
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The canonical Notch signaling pathway: unfolding the activation mechanism.
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
9
An essential role of Bmp4 in the atrioventricular septation of the mouse heart.
Kai Jiao, Holger Kulessa, Kevin Tompkins, Yingna Zhou, Lorene Batts, H Scott Baldwin, Brigid L M Hogan. Genes Dev 2003
Kai Jiao, Holger Kulessa, Kevin Tompkins, Yingna Zhou, Lorene Batts, H Scott Baldwin, Brigid L M Hogan. Genes Dev 2003
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Cell biology of cardiac cushion development.
Anthony D Person, Scott E Klewer, Raymond B Runyan. Int Rev Cytol 2005
Anthony D Person, Scott E Klewer, Raymond B Runyan. Int Rev Cytol 2005
9
Endocardial Notch Signaling in Cardiac Development and Disease.
Guillermo Luxán, Gaetano D'Amato, Donal MacGrogan, José Luis de la Pompa. Circ Res 2016
Guillermo Luxán, Gaetano D'Amato, Donal MacGrogan, José Luis de la Pompa. Circ Res 2016
9
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum.
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9
Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart.
Andy Wessels, Maurice J B van den Hoff, Richard F Adamo, Aimee L Phelps, Marie M Lockhart, Kimberly Sauls, Laura E Briggs, Russell A Norris, Bram van Wijk, Jose M Perez-Pomares,[...]. Dev Biol 2012
Andy Wessels, Maurice J B van den Hoff, Richard F Adamo, Aimee L Phelps, Marie M Lockhart, Kimberly Sauls, Laura E Briggs, Russell A Norris, Bram van Wijk, Jose M Perez-Pomares,[...]. Dev Biol 2012
9
Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos.
Joy Lincoln, Christina M Alfieri, Katherine E Yutzey. Dev Dyn 2004
Joy Lincoln, Christina M Alfieri, Katherine E Yutzey. Dev Dyn 2004
9
Lineage and morphogenetic analysis of the cardiac valves.
Frederik J de Lange, Antoon F M Moorman, Robert H Anderson, Jörg Männer, Alexandre T Soufan, Corrie de Gier-de Vries, Michael D Schneider, Sandra Webb, Maurice J B van den Hoff, Vincent M Christoffels. Circ Res 2004
Frederik J de Lange, Antoon F M Moorman, Robert H Anderson, Jörg Männer, Alexandre T Soufan, Corrie de Gier-de Vries, Michael D Schneider, Sandra Webb, Maurice J B van den Hoff, Vincent M Christoffels. Circ Res 2004
9
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish.
E C Walsh, D Y Stainier. Science 2001
E C Walsh, D Y Stainier. Science 2001
8
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression.
A Cano, M A Pérez-Moreno, I Rodrigo, A Locascio, M J Blanco, M G del Barrio, F Portillo, M A Nieto. Nat Cell Biol 2000
A Cano, M A Pérez-Moreno, I Rodrigo, A Locascio, M J Blanco, M G del Barrio, F Portillo, M A Nieto. Nat Cell Biol 2000
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Heart valve structure and function in development and disease.
Robert B Hinton, Katherine E Yutzey. Annu Rev Physiol 2011
Robert B Hinton, Katherine E Yutzey. Annu Rev Physiol 2011
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Oscillatory Flow Modulates Mechanosensitive klf2a Expression through trpv4 and trpp2 during Heart Valve Development.
Emilie Heckel, Francesco Boselli, Stéphane Roth, Alice Krudewig, Heinz-Georg Belting, Gilles Charvin, Julien Vermot. Curr Biol 2015
Emilie Heckel, Francesco Boselli, Stéphane Roth, Alice Krudewig, Heinz-Georg Belting, Gilles Charvin, Julien Vermot. Curr Biol 2015
8
Notch and interacting signalling pathways in cardiac development, disease, and regeneration.
Donal MacGrogan, Juliane Münch, José Luis de la Pompa. Nat Rev Cardiol 2018
Donal MacGrogan, Juliane Münch, José Luis de la Pompa. Nat Rev Cardiol 2018
9
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling.
Bingruo Wu, Zheng Zhang, Wendy Lui, Xiangjian Chen, Yidong Wang, Alyssa A Chamberlain, Ricardo A Moreno-Rodriguez, Roger R Markwald, Brian P O'Rourke, David J Sharp,[...]. Cell 2012
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8
Heart valve development: regulatory networks in development and disease.
Michelle D Combs, Katherine E Yutzey. Circ Res 2009
Michelle D Combs, Katherine E Yutzey. Circ Res 2009
8
Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis.
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
Mats Hellström, Li-Kun Phng, Jennifer J Hofmann, Elisabet Wallgard, Leigh Coultas, Per Lindblom, Jackelyn Alva, Ann-Katrin Nilsson, Linda Karlsson, Nicholas Gaiano,[...]. Nature 2007
8
Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis.
Lauren M Goddard, Anne-Laure Duchemin, Harini Ramalingan, Bingruo Wu, Mei Chen, Sharika Bamezai, Jisheng Yang, Li Li, Michael P Morley, Tao Wang,[...]. Dev Cell 2017
Lauren M Goddard, Anne-Laure Duchemin, Harini Ramalingan, Bingruo Wu, Mei Chen, Sharika Bamezai, Jisheng Yang, Li Li, Michael P Morley, Tao Wang,[...]. Dev Cell 2017
10
7
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer.
Xiaofeng Zheng, Julienne L Carstens, Jiha Kim, Matthew Scheible, Judith Kaye, Hikaru Sugimoto, Chia-Chin Wu, Valerie S LeBleu, Raghu Kalluri. Nature 2015
Xiaofeng Zheng, Julienne L Carstens, Jiha Kim, Matthew Scheible, Judith Kaye, Hikaru Sugimoto, Chia-Chin Wu, Valerie S LeBleu, Raghu Kalluri. Nature 2015
7
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells.
E Batlle, E Sancho, C Francí, D Domínguez, M Monfar, J Baulida, A García De Herreros. Nat Cell Biol 2000
E Batlle, E Sancho, C Francí, D Domínguez, M Monfar, J Baulida, A García De Herreros. Nat Cell Biol 2000
7
Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail.
Stefan Grotegut, Dietrich von Schweinitz, Gerhard Christofori, François Lehembre. EMBO J 2006
Stefan Grotegut, Dietrich von Schweinitz, Gerhard Christofori, François Lehembre. EMBO J 2006
7
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis.
Jing Yang, Sendurai A Mani, Joana Liu Donaher, Sridhar Ramaswamy, Raphael A Itzykson, Christophe Come, Pierre Savagner, Inna Gitelman, Andrea Richardson, Robert A Weinberg. Cell 2004
Jing Yang, Sendurai A Mani, Joana Liu Donaher, Sridhar Ramaswamy, Raphael A Itzykson, Christophe Come, Pierre Savagner, Inna Gitelman, Andrea Richardson, Robert A Weinberg. Cell 2004
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Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasis.
Jeff H Tsai, Joana Liu Donaher, Danielle A Murphy, Sandra Chau, Jing Yang. Cancer Cell 2012
Jeff H Tsai, Joana Liu Donaher, Danielle A Murphy, Sandra Chau, Jing Yang. Cancer Cell 2012
7
Endothelial Notch1 Is Required for Proper Development of the Semilunar Valves and Cardiac Outflow Tract.
Sara N Koenig, Kevin Bosse, Uddalak Majumdar, Elizabeth M Bonachea, Freddy Radtke, Vidu Garg. J Am Heart Assoc 2016
Sara N Koenig, Kevin Bosse, Uddalak Majumdar, Elizabeth M Bonachea, Freddy Radtke, Vidu Garg. J Am Heart Assoc 2016
16
Murine Jagged1/Notch signaling in the second heart field orchestrates Fgf8 expression and tissue-tissue interactions during outflow tract development.
Frances A High, Rajan Jain, Jason Z Stoller, Nicole B Antonucci, Min Min Lu, Kathleen M Loomes, Klaus H Kaestner, Warren S Pear, Jonathan A Epstein. J Clin Invest 2009
Frances A High, Rajan Jain, Jason Z Stoller, Nicole B Antonucci, Min Min Lu, Kathleen M Loomes, Klaus H Kaestner, Warren S Pear, Jonathan A Epstein. J Clin Invest 2009
7
Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart.
Julien Vermot, Arian S Forouhar, Michael Liebling, David Wu, Diane Plummer, Morteza Gharib, Scott E Fraser. PLoS Biol 2009
Julien Vermot, Arian S Forouhar, Michael Liebling, David Wu, Diane Plummer, Morteza Gharib, Scott E Fraser. PLoS Biol 2009
7
Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice.
Yukiko Sugi, Hideshi Yamamura, Hiroto Okagawa, Roger R Markwald. Dev Biol 2004
Yukiko Sugi, Hideshi Yamamura, Hiroto Okagawa, Roger R Markwald. Dev Biol 2004
7
Real-time 3D visualization of cellular rearrangements during cardiac valve formation.
Jenny Pestel, Radhan Ramadass, Sebastien Gauvrit, Christian Helker, Wiebke Herzog, Didier Y R Stainier. Development 2016
Jenny Pestel, Radhan Ramadass, Sebastien Gauvrit, Christian Helker, Wiebke Herzog, Didier Y R Stainier. Development 2016
15
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.