Sven-Eric Jordt, Diana M Bautista, Huai-Hu Chuang, David D McKemy, Peter M Zygmunt, Edward D Högestätt, Ian D Meng, David Julius. Nature 2004
Times Cited: 1349
Times Cited: 1349
Times Cited
Times Co-cited
Similarity
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin.
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
Michael Bandell, Gina M Story, Sun Wook Hwang, Veena Viswanath, Samer R Eid, Matt J Petrus, Taryn J Earley, Ardem Patapoutian. Neuron 2004
56
ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
Gina M Story, Andrea M Peier, Alison J Reeve, Samer R Eid, Johannes Mosbacher, Todd R Hricik, Taryn J Earley, Anne C Hergarden, David A Andersson, Sun Wook Hwang,[...]. Cell 2003
52
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents.
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
Diana M Bautista, Sven-Eric Jordt, Tetsuro Nikai, Pamela R Tsuruda, Andrew J Read, Jeannie Poblete, Ebenezer N Yamoah, Allan I Basbaum, David Julius. Cell 2006
38
The capsaicin receptor: a heat-activated ion channel in the pain pathway.
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
M J Caterina, M A Schumacher, M Tominaga, T A Rosen, J D Levine, D Julius. Nature 1997
35
TRP channel activation by reversible covalent modification.
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
Andrew Hinman, Huai-Hu Chuang, Diana M Bautista, David Julius. Proc Natl Acad Sci U S A 2006
26
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress.
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
David A Andersson, Clive Gentry, Sian Moss, Stuart Bevan. J Neurosci 2008
23
Pungent products from garlic activate the sensory ion channel TRPA1.
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
Diana M Bautista, Pouya Movahed, Andrew Hinman, Helena E Axelsson, Olov Sterner, Edward D Högestätt, David Julius, Sven-Eric Jordt, Peter M Zygmunt. Proc Natl Acad Sci U S A 2005
21
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
Lindsey J Macpherson, Adrienne E Dubin, Michael J Evans, Felix Marr, Peter G Schultz, Benjamin F Cravatt, Ardem Patapoutian. Nature 2007
20
TRPA1 mediates formalin-induced pain.
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
Colleen R McNamara, Josh Mandel-Brehm, Diana M Bautista, Jan Siemens, Kari L Deranian, Michael Zhao, Neil J Hayward, Jayhong A Chong, David Julius, Magdalene M Moran,[...]. Proc Natl Acad Sci U S A 2007
20
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease.
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
Karel Talavera, Justyna B Startek, Julio Alvarez-Collazo, Brett Boonen, Yeranddy A Alpizar, Alicia Sanchez, Robbe Naert, Bernd Nilius. Physiol Rev 2020
21
Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
David D McKemy, Werner M Neuhausser, David Julius. Nature 2002
19
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction.
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
Kelvin Y Kwan, Andrew J Allchorne, Melissa A Vollrath, Adam P Christensen, Duan-Sun Zhang, Clifford J Woolf, David P Corey. Neuron 2006
19
Impaired nociception and pain sensation in mice lacking the capsaicin receptor.
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
M J Caterina, A Leffler, A B Malmberg, W J Martin, J Trafton, K R Petersen-Zeitz, M Koltzenburg, A I Basbaum, D Julius. Science 2000
17
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1.
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
Marcello Trevisani, Jan Siemens, Serena Materazzi, Diana M Bautista, Romina Nassini, Barbara Campi, Noritaka Imamachi, Eunice Andrè, Riccardo Patacchini, Graeme S Cottrell,[...]. Proc Natl Acad Sci U S A 2007
17
TRPA1 acts as a cold sensor in vitro and in vivo.
Yuji Karashima, Karel Talavera, Wouter Everaerts, Annelies Janssens, Kelvin Y Kwan, Rudi Vennekens, Bernd Nilius, Thomas Voets. Proc Natl Acad Sci U S A 2009
Yuji Karashima, Karel Talavera, Wouter Everaerts, Annelies Janssens, Kelvin Y Kwan, Rudi Vennekens, Bernd Nilius, Thomas Voets. Proc Natl Acad Sci U S A 2009
17
The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin.
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
Lindsey J Macpherson, Bernhard H Geierstanger, Veena Viswanath, Michael Bandell, Samer R Eid, SunWook Hwang, Ardem Patapoutian. Curr Biol 2005
16
TRPA1 channels: molecular sentinels of cellular stress and tissue damage.
Félix Viana. J Physiol 2016
Félix Viana. J Physiol 2016
16
A TRP channel that senses cold stimuli and menthol.
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
Andrea M Peier, Aziz Moqrich, Anne C Hergarden, Alison J Reeve, David A Andersson, Gina M Story, Taryn J Earley, Ilaria Dragoni, Peter McIntyre, Stuart Bevan,[...]. Cell 2002
15
Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation.
Romina Nassini, Pamela Pedretti, Nadia Moretto, Camilla Fusi, Chiara Carnini, Fabrizio Facchinetti, Arturo Roberto Viscomi, Anna Rita Pisano, Susan Stokesberry, Charlott Brunmark,[...]. PLoS One 2012
Romina Nassini, Pamela Pedretti, Nadia Moretto, Camilla Fusi, Chiara Carnini, Fabrizio Facchinetti, Arturo Roberto Viscomi, Anna Rita Pisano, Susan Stokesberry, Charlott Brunmark,[...]. PLoS One 2012
15
TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.
Victor Meseguer, Yeranddy A Alpizar, Enoch Luis, Sendoa Tajada, Bristol Denlinger, Otto Fajardo, Jan-Albert Manenschijn, Carlos Fernández-Peña, Arturo Talavera, Tatiana Kichko,[...]. Nat Commun 2014
Victor Meseguer, Yeranddy A Alpizar, Enoch Luis, Sendoa Tajada, Bristol Denlinger, Otto Fajardo, Jan-Albert Manenschijn, Carlos Fernández-Peña, Arturo Talavera, Tatiana Kichko,[...]. Nat Commun 2014
15
Direct activation of the ion channel TRPA1 by Ca2+.
Sandra Zurborg, Brian Yurgionas, Julia A Jira, Ombretta Caspani, Paul A Heppenstall. Nat Neurosci 2007
Sandra Zurborg, Brian Yurgionas, Julia A Jira, Ombretta Caspani, Paul A Heppenstall. Nat Neurosci 2007
14
Bimodal action of menthol on the transient receptor potential channel TRPA1.
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
Yuji Karashima, Nils Damann, Jean Prenen, Karel Talavera, Andrei Segal, Thomas Voets, Bernd Nilius. J Neurosci 2007
14
Cigarette smoke-induced neurogenic inflammation is mediated by alpha,beta-unsaturated aldehydes and the TRPA1 receptor in rodents.
Eunice Andrè, Barbara Campi, Serena Materazzi, Marcello Trevisani, Silvia Amadesi, Daniela Massi, Christophe Creminon, Natalya Vaksman, Romina Nassini, Maurizio Civelli,[...]. J Clin Invest 2008
Eunice Andrè, Barbara Campi, Serena Materazzi, Marcello Trevisani, Silvia Amadesi, Daniela Massi, Christophe Creminon, Natalya Vaksman, Romina Nassini, Maurizio Civelli,[...]. J Clin Invest 2008
14
TRPA1: A gatekeeper for inflammation.
Diana M Bautista, Maurizio Pellegrino, Makoto Tsunozaki. Annu Rev Physiol 2013
Diana M Bautista, Maurizio Pellegrino, Makoto Tsunozaki. Annu Rev Physiol 2013
14
The cloned capsaicin receptor integrates multiple pain-producing stimuli.
M Tominaga, M J Caterina, A B Malmberg, T A Rosen, H Gilbert, K Skinner, B E Raumann, A I Basbaum, D Julius. Neuron 1998
M Tominaga, M J Caterina, A B Malmberg, T A Rosen, H Gilbert, K Skinner, B E Raumann, A I Basbaum, D Julius. Neuron 1998
13
Structural Insights into Electrophile Irritant Sensing by the Human TRPA1 Channel.
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
Yang Suo, Zilong Wang, Lejla Zubcevic, Allen L Hsu, Qianru He, Mario J Borgnia, Ru-Rong Ji, Seok-Yong Lee. Neuron 2020
33
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma.
Ana I Caceres, Marian Brackmann, Maxwell D Elia, Bret F Bessac, Donato del Camino, Marc D'Amours, JoAnn S Witek, Chistopher M Fanger, Jayhong A Chong, Neil J Hayward,[...]. Proc Natl Acad Sci U S A 2009
Ana I Caceres, Marian Brackmann, Maxwell D Elia, Bret F Bessac, Donato del Camino, Marc D'Amours, JoAnn S Witek, Chistopher M Fanger, Jayhong A Chong, Neil J Hayward,[...]. Proc Natl Acad Sci U S A 2009
13
TRPA1 is a major oxidant sensor in murine airway sensory neurons.
Bret F Bessac, Michael Sivula, Christian A von Hehn, Jasmine Escalera, Lauren Cohn, Sven-Eric Jordt. J Clin Invest 2008
Bret F Bessac, Michael Sivula, Christian A von Hehn, Jasmine Escalera, Lauren Cohn, Sven-Eric Jordt. J Clin Invest 2008
13
Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
Candice E Paulsen, Jean-Paul Armache, Yuan Gao, Yifan Cheng, David Julius. Nature 2015
12
A TRP channel trio mediates acute noxious heat sensing.
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
Ine Vandewauw, Katrien De Clercq, Marie Mulier, Katharina Held, Silvia Pinto, Nele Van Ranst, Andrei Segal, Thierry Voet, Rudi Vennekens, Katharina Zimmermann,[...]. Nature 2018
12
The menthol receptor TRPM8 is the principal detector of environmental cold.
Diana M Bautista, Jan Siemens, Joshua M Glazer, Pamela R Tsuruda, Allan I Basbaum, Cheryl L Stucky, Sven-Eric Jordt, David Julius. Nature 2007
Diana M Bautista, Jan Siemens, Joshua M Glazer, Pamela R Tsuruda, Allan I Basbaum, Cheryl L Stucky, Sven-Eric Jordt, David Julius. Nature 2007
12
Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity.
Lavanya Moparthi, Tatjana I Kichko, Mirjam Eberhardt, Edward D Högestätt, Per Kjellbom, Urban Johanson, Peter W Reeh, Andreas Leffler, Milos R Filipovic, Peter M Zygmunt. Sci Rep 2016
Lavanya Moparthi, Tatjana I Kichko, Mirjam Eberhardt, Edward D Högestätt, Per Kjellbom, Urban Johanson, Peter W Reeh, Andreas Leffler, Milos R Filipovic, Peter M Zygmunt. Sci Rep 2016
16
Irritant-evoked activation and calcium modulation of the TRPA1 receptor.
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
Jianhua Zhao, John V Lin King, Candice E Paulsen, Yifan Cheng, David Julius. Nature 2020
30
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.
Yi Dai, Shenglan Wang, Makoto Tominaga, Satoshi Yamamoto, Tetsuo Fukuoka, Tomohiro Higashi, Kimiko Kobayashi, Koichi Obata, Hiroki Yamanaka, Koichi Noguchi. J Clin Invest 2007
Yi Dai, Shenglan Wang, Makoto Tominaga, Satoshi Yamamoto, Tetsuo Fukuoka, Tomohiro Higashi, Kimiko Kobayashi, Koichi Obata, Hiroki Yamanaka, Koichi Noguchi. J Clin Invest 2007
11
A gain-of-function mutation in TRPA1 causes familial episodic pain syndrome.
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
Barbara Kremeyer, Francisco Lopera, James J Cox, Aliakmal Momin, Francois Rugiero, Steve Marsh, C Geoffrey Woods, Nicholas G Jones, Kathryn J Paterson, Florence R Fricker,[...]. Neuron 2010
11
Nicotine activates the chemosensory cation channel TRPA1.
Karel Talavera, Maarten Gees, Yuji Karashima, Víctor M Meseguer, Jeroen A J Vanoirbeek, Nils Damann, Wouter Everaerts, Melissa Benoit, Annelies Janssens, Rudi Vennekens,[...]. Nat Neurosci 2009
Karel Talavera, Maarten Gees, Yuji Karashima, Víctor M Meseguer, Jeroen A J Vanoirbeek, Nils Damann, Wouter Everaerts, Melissa Benoit, Annelies Janssens, Rudi Vennekens,[...]. Nat Neurosci 2009
11
Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
Keiichi Nagata, Anne Duggan, Gagan Kumar, Jaime García-Añoveros. J Neurosci 2005
Keiichi Nagata, Anne Duggan, Gagan Kumar, Jaime García-Añoveros. J Neurosci 2005
11
TRPA1 as a drug target--promise and challenges.
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
Jun Chen, David H Hackos. Naunyn Schmiedebergs Arch Pharmacol 2015
10
Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing.
Dmitry Usoskin, Alessandro Furlan, Saiful Islam, Hind Abdo, Peter Lönnerberg, Daohua Lou, Jens Hjerling-Leffler, Jesper Haeggström, Olga Kharchenko, Peter V Kharchenko,[...]. Nat Neurosci 2015
Dmitry Usoskin, Alessandro Furlan, Saiful Islam, Hind Abdo, Peter Lönnerberg, Daohua Lou, Jens Hjerling-Leffler, Jesper Haeggström, Olga Kharchenko, Peter V Kharchenko,[...]. Nat Neurosci 2015
10
Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception.
Kyeongjin Kang, Stefan R Pulver, Vincent C Panzano, Elaine C Chang, Leslie C Griffith, Douglas L Theobald, Paul A Garrity. Nature 2010
Kyeongjin Kang, Stefan R Pulver, Vincent C Panzano, Elaine C Chang, Leslie C Griffith, Douglas L Theobald, Paul A Garrity. Nature 2010
10
Species differences and molecular determinant of TRPA1 cold sensitivity.
Jun Chen, Dawon Kang, Jing Xu, Marc Lake, James O Hogan, Chaohong Sun, Karl Walter, Betty Yao, Donghee Kim. Nat Commun 2013
Jun Chen, Dawon Kang, Jing Xu, Marc Lake, James O Hogan, Chaohong Sun, Karl Walter, Betty Yao, Donghee Kim. Nat Commun 2013
10
Molecular basis of infrared detection by snakes.
Elena O Gracheva, Nicholas T Ingolia, Yvonne M Kelly, Julio F Cordero-Morales, Gunther Hollopeter, Alexander T Chesler, Elda E Sánchez, John C Perez, Jonathan S Weissman, David Julius. Nature 2010
Elena O Gracheva, Nicholas T Ingolia, Yvonne M Kelly, Julio F Cordero-Morales, Gunther Hollopeter, Alexander T Chesler, Elda E Sánchez, John C Perez, Jonathan S Weissman, David Julius. Nature 2010
10
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels.
Haoxing Xu, Markus Delling, Janice C Jun, David E Clapham. Nat Neurosci 2006
Haoxing Xu, Markus Delling, Janice C Jun, David E Clapham. Nat Neurosci 2006
9
The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions.
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
Yuanyuan Y Wang, Rui B Chang, Hang N Waters, David D McKemy, Emily R Liman. J Biol Chem 2008
9
Molecular basis for species-specific sensitivity to "hot" chili peppers.
Sven-Eric Jordt, David Julius. Cell 2002
Sven-Eric Jordt, David Julius. Cell 2002
9
Cellular and molecular mechanisms of pain.
Allan I Basbaum, Diana M Bautista, Grégory Scherrer, David Julius. Cell 2009
Allan I Basbaum, Diana M Bautista, Grégory Scherrer, David Julius. Cell 2009
9
Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.
Ruzanna Atoyan, Doug Shander, Natalia V Botchkareva. J Invest Dermatol 2009
Ruzanna Atoyan, Doug Shander, Natalia V Botchkareva. J Invest Dermatol 2009
9
The transient receptor potential channel TRPA1: from gene to pathophysiology.
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
Bernd Nilius, Giovanni Appendino, Grzegorz Owsianik. Pflugers Arch 2012
9
Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
Bailong Xiao, Adrienne E Dubin, Badry Bursulaya, Veena Viswanath, Timothy J Jegla, Ardem Patapoutian. J Neurosci 2008
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.