A citation-based method for searching scientific literature

Eicke Latz, Annett Schoenemeyer, Alberto Visintin, Katherine A Fitzgerald, Brian G Monks, Cathrine F Knetter, Egil Lien, Nadra J Nilsen, Terje Espevik, Douglas T Golenbock. Nat Immunol 2004
Times Cited: 986







List of co-cited articles
877 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


A Toll-like receptor recognizes bacterial DNA.
H Hemmi, O Takeuchi, T Kawai, T Kaisho, S Sato, H Sanjo, M Matsumoto, K Hoshino, H Wagner, K Takeda,[...]. Nature 2000
30


Circulating mitochondrial DAMPs cause inflammatory responses to injury.
Qin Zhang, Mustafa Raoof, Yu Chen, Yuka Sumi, Tolga Sursal, Wolfgang Junger, Karim Brohi, Kiyoshi Itagaki, Carl J Hauser. Nature 2010
16

TLR9 is localized in the endoplasmic reticulum prior to stimulation.
Cynthia A Leifer, Margaret N Kennedy, Alessandra Mazzoni, ChangWoo Lee, Michael J Kruhlak, David M Segal. J Immunol 2004
248
16

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.
Sarah E Ewald, Bettina L Lee, Laura Lau, Katherine E Wickliffe, Guo-Ping Shi, Harold A Chapman, Gregory M Barton. Nature 2008
412
15

CpG motifs in bacterial DNA and their immune effects.
Arthur M Krieg. Annu Rev Immunol 2002
14

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.
You-Me Kim, Melanie M Brinkmann, Marie-Eve Paquet, Hidde L Ploegh. Nature 2008
466
14

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9.
Boyoun Park, Melanie M Brinkmann, Eric Spooner, Clarissa C Lee, You-Me Kim, Hidde L Ploegh. Nat Immunol 2008
345
13

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.
Lijun Sun, Jiaxi Wu, Fenghe Du, Xiang Chen, Zhijian J Chen. Science 2013
12

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9.
Koichi Tabeta, Kasper Hoebe, Edith M Janssen, Xin Du, Philippe Georgel, Karine Crozat, Suzanne Mudd, Navjiwan Mann, Sosathya Sovath, Jason Goode,[...]. Nat Immunol 2006
489
11

Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells.
F Takeshita, C A Leifer, I Gursel, K J Ishii, S Takeshita, M Gursel, D M Klinman. J Immunol 2001
452
10

Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3.
Miwa Sasai, Melissa M Linehan, Akiko Iwasaki. Science 2010
239
10


Pattern recognition receptors and inflammation.
Osamu Takeuchi, Shizuo Akira. Cell 2010
10

CpG motifs in bacterial DNA trigger direct B-cell activation.
A M Krieg, A K Yi, S Matson, T J Waldschmidt, G A Bishop, R Teasdale, G A Koretzky, D M Klinman. Nature 1995
10

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure.
Takafumi Oka, Shungo Hikoso, Osamu Yamaguchi, Manabu Taneike, Toshihiro Takeda, Takahito Tamai, Jota Oyabu, Tomokazu Murakawa, Hiroyuki Nakayama, Kazuhiko Nishida,[...]. Nature 2012
645
9

Intracellular toll-like receptors.
Amanda L Blasius, Bruce Beutler. Immunity 2010
730
9

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3.
L Alexopoulou, A C Holt, R Medzhitov, R A Flavell. Nature 2001
9

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.
Sarah E Ewald, Alex Engel, Jiyoun Lee, Miqi Wang, Matthew Bogyo, Gregory M Barton. J Exp Med 2011
196
9

Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells.
Fernando E Sepulveda, Sophia Maschalidi, Renaud Colisson, Lea Heslop, Cristina Ghirelli, Emna Sakka, Ana-Maria Lennon-Duménil, Sebastian Amigorena, Lucien Cabanie, Bénédicte Manoury. Immunity 2009
202
9

Pathogen recognition and innate immunity.
Shizuo Akira, Satoshi Uematsu, Osamu Takeuchi. Cell 2006
9

The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Karin Pelka, Damien Bertheloot, Elisa Reimer, Kshiti Phulphagar, Susanne V Schmidt, Anette Christ, Rainer Stahl, Nicki Watson, Kensuke Miyake, Nir Hacohen,[...]. Immunity 2018
46
19

Ligand-induced conformational changes allosterically activate Toll-like receptor 9.
Eicke Latz, Anjali Verma, Alberto Visintin, Mei Gong, Cherilyn M Sirois, Dionne C G Klein, Brian G Monks, C James McKnight, Marc S Lamphier, W Paul Duprex,[...]. Nat Immunol 2007
315
8

Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.
Kenya Honda, Yusuke Ohba, Hideyuki Yanai, Hideo Negishi, Tatsuaki Mizutani, Akinori Takaoka, Choji Taya, Tadatsugu Taniguchi. Nature 2005
658
8

UNC93B1 mediates differential trafficking of endosomal TLRs.
Bettina L Lee, Joanne E Moon, Jeffrey H Shu, Lin Yuan, Zachary R Newman, Randy Schekman, Gregory M Barton. Elife 2013
148
8


Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells.
Jennifer Lund, Ayuko Sato, Shizuo Akira, Ruslan Medzhitov, Akiko Iwasaki. J Exp Med 2003
870
8

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.
Irma Garcia-Martinez, Nicola Santoro, Yonglin Chen, Rafaz Hoque, Xinshou Ouyang, Sonia Caprio, Mark J Shlomchik, Robert Lee Coffman, Albert Candia, Wajahat Zafar Mehal. J Clin Invest 2016
218
8

Therapeutic potential of Toll-like receptor 9 activation.
Arthur M Krieg. Nat Rev Drug Discov 2006
880
8

Toll-like receptor signalling.
Shizuo Akira, Kiyoshi Takeda. Nat Rev Immunol 2004
7

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.
Florian Heil, Hiroaki Hemmi, Hubertus Hochrein, Franziska Ampenberger, Carsten Kirschning, Shizuo Akira, Grayson Lipford, Hermann Wagner, Stefan Bauer. Science 2004
7

Immunotherapeutic uses of CpG oligodeoxynucleotides.
Dennis M Klinman. Nat Rev Immunol 2004
623
7

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition.
S Bauer, C J Kirschning, H Häcker, V Redecke, S Hausmann, S Akira, H Wagner, G B Lipford. Proc Natl Acad Sci U S A 2001
7

Below the surface: The inner lives of TLR4 and TLR9.
Laura Marongiu, Laura Gornati, Irene Artuso, Ivan Zanoni, Francesca Granucci. J Leukoc Biol 2019
36
19

IRAP+ endosomes restrict TLR9 activation and signaling.
Joel Babdor, Delphyne Descamps, Aimé Cézaire Adiko, Mira Tohmé, Sophia Maschalidi, Irini Evnouchidou, Luiz Ricardo Vasconcellos, Mariacristina De Luca, Francois-Xavier Mauvais, Meriem Garfa-Traore,[...]. Nat Immunol 2017
22
31

Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.
Jiaxi Wu, Lijun Sun, Xiang Chen, Fenghe Du, Heping Shi, Chuo Chen, Zhijian J Chen. Science 2013
7

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.
Xu Zhang, Heping Shi, Jiaxi Wu, Xuewu Zhang, Lijun Sun, Chuo Chen, Zhijian J Chen. Mol Cell 2013
467
7

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA.
Teresa Fernandes-Alnemri, Je-Wook Yu, Pinaki Datta, Jianghong Wu, Emad S Alnemri. Nature 2009
7

Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Kenichi Shimada, Timothy R Crother, Justin Karlin, Jargalsaikhan Dagvadorj, Norika Chiba, Shuang Chen, V Krishnan Ramanujan, Andrea J Wolf, Laurent Vergnes, David M Ojcius,[...]. Immunity 2012
7

Trafficking of endosomal Toll-like receptors.
Bettina L Lee, Gregory M Barton. Trends Cell Biol 2014
107
7

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5.
F Hayashi, K D Smith, A Ozinsky, T R Hawn, E C Yi, D R Goodlett, J K Eng, S Akira, D M Underhill, A Aderem. Nature 2001
6

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists.
Jörg Vollmer, Arthur M Krieg. Adv Drug Deliv Rev 2009
359
6

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation.
Cristiana Guiducci, Gary Ott, Jean H Chan, Emily Damon, Carlo Calacsan, Tracy Matray, Kyung-Dall Lee, Robert L Coffman, Franck J Barrat. J Exp Med 2006
276
6

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides.
Veit Hornung, Simon Rothenfusser, Stefanie Britsch, Anne Krug, Bernd Jahrsdörfer, Thomas Giese, Stefan Endres, Gunther Hartmann. J Immunol 2002
6


Inflammasomes: mechanism of assembly, regulation and signalling.
Petr Broz, Vishva M Dixit. Nat Rev Immunol 2016
6

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.
Sandra S Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi, Shizuo Akira, Caetano Reis e Sousa. Science 2004
6

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.
Xiao-Dong Li, Jiaxi Wu, Daxing Gao, Hua Wang, Lijun Sun, Zhijian J Chen. Science 2013
563
6

IFI16 is an innate immune sensor for intracellular DNA.
Leonie Unterholzner, Sinead E Keating, Marcin Baran, Kristy A Horan, Søren B Jensen, Shruti Sharma, Cherilyn M Sirois, Tengchuan Jin, Eicke Latz, T Sam Xiao,[...]. Nat Immunol 2010
6

Signaling to NF-kappaB by Toll-like receptors.
Taro Kawai, Shizuo Akira. Trends Mol Med 2007
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.