Wolfgang J Streit, Nicole W Sammons, Amanda J Kuhns, D Larry Sparks. Glia 2004
Times Cited: 412
Times Cited: 412
Times Cited
Times Co-cited
Similarity
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo.
Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen. Science 2005
Axel Nimmerjahn, Frank Kirchhoff, Fritjof Helmchen. Science 2005
36
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.
Wolfgang J Streit, Heiko Braak, Qing-Shan Xue, Ingo Bechmann. Acta Neuropathol 2009
Wolfgang J Streit, Heiko Braak, Qing-Shan Xue, Ingo Bechmann. Acta Neuropathol 2009
32
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
27
Microglia derived from aging mice exhibit an altered inflammatory profile.
Amanda Sierra, Andres C Gottfried-Blackmore, Bruce S McEwen, Karen Bulloch. Glia 2007
Amanda Sierra, Andres C Gottfried-Blackmore, Bruce S McEwen, Karen Bulloch. Glia 2007
27
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Kathleen Grabert, Tom Michoel, Michail H Karavolos, Sara Clohisey, J Kenneth Baillie, Mark P Stevens, Tom C Freeman, Kim M Summers, Barry W McColl. Nat Neurosci 2016
Kathleen Grabert, Tom Michoel, Michail H Karavolos, Sara Clohisey, J Kenneth Baillie, Mark P Stevens, Tom C Freeman, Kim M Summers, Barry W McColl. Nat Neurosci 2016
24
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.
Timothy R Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J Walker, Frederick Gergits, Michael Segel, James Nemesh,[...]. Immunity 2019
Timothy R Hammond, Connor Dufort, Lasse Dissing-Olesen, Stefanie Giera, Adam Young, Alec Wysoker, Alec J Walker, Frederick Gergits, Michael Segel, James Nemesh,[...]. Immunity 2019
24
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes.
Thais F Galatro, Inge R Holtman, Antonio M Lerario, Ilia D Vainchtein, Nieske Brouwer, Paula R Sola, Mariana M Veras, Tulio F Pereira, Renata E P Leite, Thomas Möller,[...]. Nat Neurosci 2017
Thais F Galatro, Inge R Holtman, Antonio M Lerario, Ilia D Vainchtein, Nieske Brouwer, Paula R Sola, Mariana M Veras, Tulio F Pereira, Renata E P Leite, Thomas Möller,[...]. Nat Neurosci 2017
23
Review: microglia of the aged brain: primed to be activated and resistant to regulation.
D M Norden, J P Godbout. Neuropathol Appl Neurobiol 2013
D M Norden, J P Godbout. Neuropathol Appl Neurobiol 2013
22
The microglial sensome revealed by direct RNA sequencing.
Suzanne E Hickman, Nathan D Kingery, Toshiro K Ohsumi, Mark L Borowsky, Li-chong Wang, Terry K Means, Joseph El Khoury. Nat Neurosci 2013
Suzanne E Hickman, Nathan D Kingery, Toshiro K Ohsumi, Mark L Borowsky, Li-chong Wang, Terry K Means, Joseph El Khoury. Nat Neurosci 2013
21
Fate mapping analysis reveals that adult microglia derive from primitive macrophages.
Florent Ginhoux, Melanie Greter, Marylene Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, Mark F Mehler, Simon J Conway, Lai Guan Ng, E Richard Stanley,[...]. Science 2010
Florent Ginhoux, Melanie Greter, Marylene Leboeuf, Sayan Nandi, Peter See, Solen Gokhan, Mark F Mehler, Simon J Conway, Lai Guan Ng, E Richard Stanley,[...]. Science 2010
21
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno, Rachid El Fatimy, Lien Beckers, Elaine O'Loughlin, Yang Xu, Zain Fanek,[...]. Immunity 2017
21
Age-related myelin degradation burdens the clearance function of microglia during aging.
Shima Safaiyan, Nirmal Kannaiyan, Nicolas Snaidero, Simone Brioschi, Knut Biber, Simon Yona, Aimee L Edinger, Steffen Jung, Moritz J Rossner, Mikael Simons. Nat Neurosci 2016
Shima Safaiyan, Nirmal Kannaiyan, Nicolas Snaidero, Simone Brioschi, Knut Biber, Simon Yona, Aimee L Edinger, Steffen Jung, Moritz J Rossner, Mikael Simons. Nat Neurosci 2016
21
Age-related alterations in the dynamic behavior of microglia.
Mausam R Damani, Lian Zhao, Aurora M Fontainhas, Juan Amaral, Robert N Fariss, Wai T Wong. Aging Cell 2011
Mausam R Damani, Lian Zhao, Aurora M Fontainhas, Juan Amaral, Robert N Fariss, Wai T Wong. Aging Cell 2011
21
Homeostatic and injury-induced microglia behavior in the aging brain.
Jasmin K Hefendehl, Jonas J Neher, Rafael B Sühs, Shinichi Kohsaka, Angelos Skodras, Mathias Jucker. Aging Cell 2014
Jasmin K Hefendehl, Jonas J Neher, Rafael B Sühs, Shinichi Kohsaka, Angelos Skodras, Mathias Jucker. Aging Cell 2014
21
ATP mediates rapid microglial response to local brain injury in vivo.
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V Kim, Yi Zuo, Steffen Jung, Dan R Littman, Michael L Dustin, Wen-Biao Gan. Nat Neurosci 2005
Dimitrios Davalos, Jaime Grutzendler, Guang Yang, Jiyun V Kim, Yi Zuo, Steffen Jung, Dan R Littman, Michael L Dustin, Wen-Biao Gan. Nat Neurosci 2005
20
Synaptic pruning by microglia is necessary for normal brain development.
Rosa C Paolicelli, Giulia Bolasco, Francesca Pagani, Laura Maggi, Maria Scianni, Patrizia Panzanelli, Maurizio Giustetto, Tiago Alves Ferreira, Eva Guiducci, Laura Dumas,[...]. Science 2011
Rosa C Paolicelli, Giulia Bolasco, Francesca Pagani, Laura Maggi, Maria Scianni, Patrizia Panzanelli, Maurizio Giustetto, Tiago Alves Ferreira, Eva Guiducci, Laura Dumas,[...]. Science 2011
18
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner.
Dorothy P Schafer, Emily K Lehrman, Amanda G Kautzman, Ryuta Koyama, Alan R Mardinly, Ryo Yamasaki, Richard M Ransohoff, Michael E Greenberg, Ben A Barres, Beth Stevens. Neuron 2012
Dorothy P Schafer, Emily K Lehrman, Amanda G Kautzman, Ryuta Koyama, Alan R Mardinly, Ryo Yamasaki, Richard M Ransohoff, Michael E Greenberg, Ben A Barres, Beth Stevens. Neuron 2012
18
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.
Julia Marschallinger, Tal Iram, Macy Zardeneta, Song E Lee, Benoit Lehallier, Michael S Haney, John V Pluvinage, Vidhu Mathur, Oliver Hahn, David W Morgens,[...]. Nat Neurosci 2020
Julia Marschallinger, Tal Iram, Macy Zardeneta, Song E Lee, Benoit Lehallier, Michael S Haney, John V Pluvinage, Vidhu Mathur, Oliver Hahn, David W Morgens,[...]. Nat Neurosci 2020
18
Identification of a unique TGF-β-dependent molecular and functional signature in microglia.
Oleg Butovsky, Mark P Jedrychowski, Craig S Moore, Ron Cialic, Amanda J Lanser, Galina Gabriely, Thomas Koeglsperger, Ben Dake, Pauline M Wu, Camille E Doykan,[...]. Nat Neurosci 2014
Oleg Butovsky, Mark P Jedrychowski, Craig S Moore, Ron Cialic, Amanda J Lanser, Galina Gabriely, Thomas Koeglsperger, Ben Dake, Pauline M Wu, Camille E Doykan,[...]. Nat Neurosci 2014
17
Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease.
Danielle S Davies, Jolande Ma, Thuvarahan Jegathees, Claire Goldsbury. Brain Pathol 2017
Danielle S Davies, Jolande Ma, Thuvarahan Jegathees, Claire Goldsbury. Brain Pathol 2017
17
Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines.
Christopher J Henry, Yan Huang, Angela M Wynne, Jonathan P Godbout. Brain Behav Immun 2009
Christopher J Henry, Yan Huang, Angela M Wynne, Jonathan P Godbout. Brain Behav Immun 2009
17
A transcriptomic atlas of aged human microglia.
Marta Olah, Ellis Patrick, Alexandra-Chloe Villani, Jishu Xu, Charles C White, Katie J Ryan, Paul Piehowski, Alifiya Kapasi, Parham Nejad, Maria Cimpean,[...]. Nat Commun 2018
Marta Olah, Ellis Patrick, Alexandra-Chloe Villani, Jishu Xu, Charles C White, Katie J Ryan, Paul Piehowski, Alifiya Kapasi, Parham Nejad, Maria Cimpean,[...]. Nat Commun 2018
17
Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.
Takahiro Masuda, Roman Sankowski, Ori Staszewski, Chotima Böttcher, Lukas Amann, Sagar, Christian Scheiwe, Stefan Nessler, Patrik Kunz, Geert van Loo,[...]. Nature 2019
Takahiro Masuda, Roman Sankowski, Ori Staszewski, Chotima Böttcher, Lukas Amann, Sagar, Christian Scheiwe, Stefan Nessler, Patrik Kunz, Geert van Loo,[...]. Nature 2019
16
Complement and microglia mediate early synapse loss in Alzheimer mouse models.
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
Soyon Hong, Victoria F Beja-Glasser, Bianca M Nfonoyim, Arnaud Frouin, Shaomin Li, Saranya Ramakrishnan, Katherine M Merry, Qiaoqiao Shi, Arnon Rosenthal, Ben A Barres,[...]. Science 2016
16
Microglia and the aging brain: are senescent microglia the key to neurodegeneration?
Dafina M Angelova, David R Brown. J Neurochem 2019
Dafina M Angelova, David R Brown. J Neurochem 2019
25
15
Neurotoxic reactive astrocytes are induced by activated microglia.
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
Shane A Liddelow, Kevin A Guttenplan, Laura E Clarke, Frederick C Bennett, Christopher J Bohlen, Lucas Schirmer, Mariko L Bennett, Alexandra E Münch, Won-Suk Chung, Todd C Peterson,[...]. Nature 2017
15
Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain.
Katharine Askew, Kaizhen Li, Adrian Olmos-Alonso, Fernando Garcia-Moreno, Yajie Liang, Philippa Richardson, Tom Tipton, Mark A Chapman, Kristoffer Riecken, Sol Beccari,[...]. Cell Rep 2017
Katharine Askew, Kaizhen Li, Adrian Olmos-Alonso, Fernando Garcia-Moreno, Yajie Liang, Philippa Richardson, Tom Tipton, Mark A Chapman, Kristoffer Riecken, Sol Beccari,[...]. Cell Rep 2017
15
Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function.
Emalick G Njie, Ellen Boelen, Frank R Stassen, Harry W M Steinbusch, David R Borchelt, Wolfgang J Streit. Neurobiol Aging 2012
Emalick G Njie, Ellen Boelen, Frank R Stassen, Harry W M Steinbusch, David R Borchelt, Wolfgang J Streit. Neurobiol Aging 2012
15
Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices.
Marie-Ève Tremblay, Martha L Zettel, James R Ison, Paul D Allen, Ania K Majewska. Glia 2012
Marie-Ève Tremblay, Martha L Zettel, James R Ison, Paul D Allen, Ania K Majewska. Glia 2012
15
Physiology of microglia.
Helmut Kettenmann, Uwe-Karsten Hanisch, Mami Noda, Alexei Verkhratsky. Physiol Rev 2011
Helmut Kettenmann, Uwe-Karsten Hanisch, Mami Noda, Alexei Verkhratsky. Physiol Rev 2011
15
14
Microglial pathology.
Wolfgang J Streit, Qing-Shan Xue, Jasmin Tischer, Ingo Bechmann. Acta Neuropathol Commun 2014
Wolfgang J Streit, Qing-Shan Xue, Jasmin Tischer, Ingo Bechmann. Acta Neuropathol Commun 2014
14
Inhomogeneous distribution of Iba-1 characterizes microglial pathology in Alzheimer's disease.
Jasmin Tischer, Martin Krueger, Wolf Mueller, Ori Staszewski, Marco Prinz, Wolfgang J Streit, Ingo Bechmann. Glia 2016
Jasmin Tischer, Martin Krueger, Wolf Mueller, Ori Staszewski, Marco Prinz, Wolfgang J Streit, Ingo Bechmann. Glia 2016
21
Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
14
Exaggerated neuroinflammation and sickness behavior in aged mice following activation of the peripheral innate immune system.
J P Godbout, J Chen, J Abraham, A F Richwine, B M Berg, K W Kelley, R W Johnson. FASEB J 2005
J P Godbout, J Chen, J Abraham, A F Richwine, B M Berg, K W Kelley, R W Johnson. FASEB J 2005
14
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline.
Tyler J Bussian, Asef Aziz, Charlton F Meyer, Barbara L Swenson, Jan M van Deursen, Darren J Baker. Nature 2018
Tyler J Bussian, Asef Aziz, Charlton F Meyer, Barbara L Swenson, Jan M van Deursen, Darren J Baker. Nature 2018
14
Dystrophic microglia in late-onset Alzheimer's disease.
Wolfgang J Streit, Habibeh Khoshbouei, Ingo Bechmann. Glia 2020
Wolfgang J Streit, Habibeh Khoshbouei, Ingo Bechmann. Glia 2020
29
Microglia Priming with Aging and Stress.
Anzela Niraula, John F Sheridan, Jonathan P Godbout. Neuropsychopharmacology 2017
Anzela Niraula, John F Sheridan, Jonathan P Godbout. Neuropsychopharmacology 2017
14
Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice.
Suzanne E Hickman, Elizabeth K Allison, Joseph El Khoury. J Neurosci 2008
Suzanne E Hickman, Elizabeth K Allison, Joseph El Khoury. J Neurosci 2008
13
Microglial dystrophy in the aged and Alzheimer's disease brain is associated with ferritin immunoreactivity.
Kryslaine O Lopes, D Larry Sparks, Wolfgang J Streit. Glia 2008
Kryslaine O Lopes, D Larry Sparks, Wolfgang J Streit. Glia 2008
13
Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging.
Adam D Bachstetter, Linda J Van Eldik, Frederick A Schmitt, Janna H Neltner, Eseosa T Ighodaro, Scott J Webster, Ela Patel, Erin L Abner, Richard J Kryscio, Peter T Nelson. Acta Neuropathol Commun 2015
Adam D Bachstetter, Linda J Van Eldik, Frederick A Schmitt, Janna H Neltner, Eseosa T Ighodaro, Scott J Webster, Ela Patel, Erin L Abner, Richard J Kryscio, Peter T Nelson. Acta Neuropathol Commun 2015
13
Microglial senescence: does the brain's immune system have an expiration date?
Wolfgang J Streit. Trends Neurosci 2006
Wolfgang J Streit. Trends Neurosci 2006
13
High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease.
Dunja Mrdjen, Anto Pavlovic, Felix J Hartmann, Bettina Schreiner, Sebastian G Utz, Brian P Leung, Iva Lelios, Frank L Heppner, Jonathan Kipnis, Doron Merkler,[...]. Immunity 2018
Dunja Mrdjen, Anto Pavlovic, Felix J Hartmann, Bettina Schreiner, Sebastian G Utz, Brian P Leung, Iva Lelios, Frank L Heppner, Jonathan Kipnis, Doron Merkler,[...]. Immunity 2018
12
Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
12
Microglial dysfunction in brain aging and Alzheimer's disease.
Kira Irving Mosher, Tony Wyss-Coray. Biochem Pharmacol 2014
Kira Irving Mosher, Tony Wyss-Coray. Biochem Pharmacol 2014
12
TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
12
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.
Bahareh Ajami, Jami L Bennett, Charles Krieger, Wolfram Tetzlaff, Fabio M V Rossi. Nat Neurosci 2007
Bahareh Ajami, Jami L Bennett, Charles Krieger, Wolfram Tetzlaff, Fabio M V Rossi. Nat Neurosci 2007
12
Dark microglia: A new phenotype predominantly associated with pathological states.
Kanchan Bisht, Kaushik P Sharma, Cynthia Lecours, Maria Gabriela Sánchez, Hassan El Hajj, Giampaolo Milior, Adrián Olmos-Alonso, Diego Gómez-Nicola, Giamal Luheshi, Luc Vallières,[...]. Glia 2016
Kanchan Bisht, Kaushik P Sharma, Cynthia Lecours, Maria Gabriela Sánchez, Hassan El Hajj, Giampaolo Milior, Adrián Olmos-Alonso, Diego Gómez-Nicola, Giamal Luheshi, Luc Vallières,[...]. Glia 2016
12
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis.
Inge R Holtman, Divya D Raj, Jeremy A Miller, Wandert Schaafsma, Zhuoran Yin, Nieske Brouwer, Paul D Wes, Thomas Möller, Marie Orre, Willem Kamphuis,[...]. Acta Neuropathol Commun 2015
Inge R Holtman, Divya D Raj, Jeremy A Miller, Wandert Schaafsma, Zhuoran Yin, Nieske Brouwer, Paul D Wes, Thomas Möller, Marie Orre, Willem Kamphuis,[...]. Acta Neuropathol Commun 2015
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.