Mats I Ekstrand, Maria Falkenberg, Anja Rantanen, Chan Bae Park, Martina Gaspari, Kjell Hultenby, Pierre Rustin, Claes M Gustafsson, Nils-Göran Larsson. Hum Mol Genet 2004
Times Cited: 582
Times Cited: 582
Times Cited
Times Co-cited
Similarity
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
31
The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.
Brett A Kaufman, Nela Durisic, Jeffrey M Mativetsky, Santiago Costantino, Mark A Hancock, Peter Grutter, Eric A Shoubridge. Mol Biol Cell 2007
Brett A Kaufman, Nela Durisic, Jeffrey M Mativetsky, Santiago Costantino, Mark A Hancock, Peter Grutter, Eric A Shoubridge. Mol Biol Cell 2007
19
Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
Christian Kukat, Karen M Davies, Christian A Wurm, Henrik Spåhr, Nina A Bonekamp, Inge Kühl, Friederike Joos, Paola Loguercio Polosa, Chan Bae Park, Viktor Posse,[...]. Proc Natl Acad Sci U S A 2015
Christian Kukat, Karen M Davies, Christian A Wurm, Henrik Spåhr, Nina A Bonekamp, Inge Kühl, Friederike Joos, Paola Loguercio Polosa, Chan Bae Park, Viktor Posse,[...]. Proc Natl Acad Sci U S A 2015
16
Human mitochondrial DNA is packaged with TFAM.
Tanfis Istiaq Alam, Tomotake Kanki, Tsuyoshi Muta, Koutarou Ukaji, Yoshito Abe, Hiroshi Nakayama, Koji Takio, Naotaka Hamasaki, Dongchon Kang. Nucleic Acids Res 2003
Tanfis Istiaq Alam, Tomotake Kanki, Tsuyoshi Muta, Koutarou Ukaji, Yoshito Abe, Hiroshi Nakayama, Koji Takio, Naotaka Hamasaki, Dongchon Kang. Nucleic Acids Res 2003
16
Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
Christian Kukat, Christian A Wurm, Henrik Spåhr, Maria Falkenberg, Nils-Göran Larsson, Stefan Jakobs. Proc Natl Acad Sci U S A 2011
16
Maintenance and Expression of Mammalian Mitochondrial DNA.
Claes M Gustafsson, Maria Falkenberg, Nils-Göran Larsson. Annu Rev Biochem 2016
Claes M Gustafsson, Maria Falkenberg, Nils-Göran Larsson. Annu Rev Biochem 2016
16
The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA.
Huu B Ngo, Jens T Kaiser, David C Chan. Nat Struct Mol Biol 2011
Huu B Ngo, Jens T Kaiser, David C Chan. Nat Struct Mol Biol 2011
13
Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM).
Yuichi Matsushima, Yu-ichi Goto, Laurie S Kaguni. Proc Natl Acad Sci U S A 2010
Yuichi Matsushima, Yu-ichi Goto, Laurie S Kaguni. Proc Natl Acad Sci U S A 2010
12
Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.
Bin Lu, Jae Lee, Xiaobo Nie, Min Li, Yaroslav I Morozov, Sundararajan Venkatesh, Daniel F Bogenhagen, Dmitry Temiakov, Carolyn K Suzuki. Mol Cell 2013
Bin Lu, Jae Lee, Xiaobo Nie, Min Li, Yaroslav I Morozov, Sundararajan Venkatesh, Daniel F Bogenhagen, Dmitry Temiakov, Carolyn K Suzuki. Mol Cell 2013
12
Sequence and organization of the human mitochondrial genome.
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
S Anderson, A T Bankier, B G Barrell, M H de Bruijn, A R Coulson, J Drouin, I C Eperon, D P Nierlich, B A Roe, F Sanger,[...]. Nature 1981
12
Mitochondrial DNA stress primes the antiviral innate immune response.
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
A Phillip West, William Khoury-Hanold, Matthew Staron, Michal C Tal, Cristiana M Pineda, Sabine M Lang, Megan Bestwick, Brett A Duguay, Nuno Raimundo, Donna A MacDuff,[...]. Nature 2015
11
Superresolution fluorescence imaging of mitochondrial nucleoids reveals their spatial range, limits, and membrane interaction.
Timothy A Brown, Ariana N Tkachuk, Gleb Shtengel, Benjamin G Kopek, Daniel F Bogenhagen, Harald F Hess, David A Clayton. Mol Cell Biol 2011
Timothy A Brown, Ariana N Tkachuk, Gleb Shtengel, Benjamin G Kopek, Daniel F Bogenhagen, Harald F Hess, David A Clayton. Mol Cell Biol 2011
11
In vitro-reconstituted nucleoids can block mitochondrial DNA replication and transcription.
Géraldine Farge, Majda Mehmedovic, Marian Baclayon, Siet M J L van den Wildenberg, Wouter H Roos, Claes M Gustafsson, Gijs J L Wuite, Maria Falkenberg. Cell Rep 2014
Géraldine Farge, Majda Mehmedovic, Marian Baclayon, Siet M J L van den Wildenberg, Wouter H Roos, Claes M Gustafsson, Gijs J L Wuite, Maria Falkenberg. Cell Rep 2014
18
Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions.
Dongchon Kang, Sang Ho Kim, Naotaka Hamasaki. Mitochondrion 2007
Dongchon Kang, Sang Ho Kim, Naotaka Hamasaki. Mitochondrion 2007
11
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Huu B Ngo, Geoffrey A Lovely, Rob Phillips, David C Chan. Nat Commun 2014
Huu B Ngo, Geoffrey A Lovely, Rob Phillips, David C Chan. Nat Commun 2014
11
Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA.
Tomotake Kanki, Kippei Ohgaki, Martina Gaspari, Claes M Gustafsson, Atsushi Fukuoh, Narie Sasaki, Naotaka Hamasaki, Dongchon Kang. Mol Cell Biol 2004
Tomotake Kanki, Kippei Ohgaki, Martina Gaspari, Claes M Gustafsson, Atsushi Fukuoh, Narie Sasaki, Naotaka Hamasaki, Dongchon Kang. Mol Cell Biol 2004
10
Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter.
Anna Rubio-Cosials, Jasmin F Sidow, Nereida Jiménez-Menéndez, Pablo Fernández-Millán, Julio Montoya, Howard T Jacobs, Miquel Coll, Pau Bernadó, Maria Solà. Nat Struct Mol Biol 2011
Anna Rubio-Cosials, Jasmin F Sidow, Nereida Jiménez-Menéndez, Pablo Fernández-Millán, Julio Montoya, Howard T Jacobs, Miquel Coll, Pau Bernadó, Maria Solà. Nat Struct Mol Biol 2011
10
Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress.
Masataka Ikeda, Tomomi Ide, Takeo Fujino, Shinobu Arai, Keita Saku, Takamori Kakino, Henna Tyynismaa, Toshihide Yamasaki, Ken-Ichi Yamada, Dongchon Kang,[...]. PLoS One 2015
Masataka Ikeda, Tomomi Ide, Takeo Fujino, Shinobu Arai, Keita Saku, Takamori Kakino, Henna Tyynismaa, Toshihide Yamasaki, Ken-Ichi Yamada, Dongchon Kang,[...]. PLoS One 2015
13
Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells.
Jaakko L O Pohjoismäki, Sjoerd Wanrooij, Anne K Hyvärinen, Steffi Goffart, Ian J Holt, Johannes N Spelbrink, Howard T Jacobs. Nucleic Acids Res 2006
Jaakko L O Pohjoismäki, Sjoerd Wanrooij, Anne K Hyvärinen, Steffi Goffart, Ian J Holt, Johannes N Spelbrink, Howard T Jacobs. Nucleic Acids Res 2006
9
Composition and dynamics of human mitochondrial nucleoids.
Nuria Garrido, Lorena Griparic, Eija Jokitalo, Jorma Wartiovaara, Alexander M van der Bliek, Johannes N Spelbrink. Mol Biol Cell 2003
Nuria Garrido, Lorena Griparic, Eija Jokitalo, Jorma Wartiovaara, Alexander M van der Bliek, Johannes N Spelbrink. Mol Biol Cell 2003
9
The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms.
Inhae Kang, Charleen T Chu, Brett A Kaufman. FEBS Lett 2018
Inhae Kang, Charleen T Chu, Brett A Kaufman. FEBS Lett 2018
8
Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
8
The layered structure of human mitochondrial DNA nucleoids.
Daniel F Bogenhagen, Denis Rousseau, Stephanie Burke. J Biol Chem 2008
Daniel F Bogenhagen, Denis Rousseau, Stephanie Burke. J Biol Chem 2008
8
Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.
Sjoerd Wanrooij, Javier Miralles Fusté, Géraldine Farge, Yonghong Shi, Claes M Gustafsson, Maria Falkenberg. Proc Natl Acad Sci U S A 2008
Sjoerd Wanrooij, Javier Miralles Fusté, Géraldine Farge, Yonghong Shi, Claes M Gustafsson, Maria Falkenberg. Proc Natl Acad Sci U S A 2008
7
Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number.
Henna Tyynismaa, Hiroshi Sembongi, Monika Bokori-Brown, Caroline Granycome, Neil Ashley, Joanna Poulton, Anu Jalanko, Johannes N Spelbrink, Ian J Holt, Anu Suomalainen. Hum Mol Genet 2004
Henna Tyynismaa, Hiroshi Sembongi, Monika Bokori-Brown, Caroline Granycome, Neil Ashley, Joanna Poulton, Anu Jalanko, Johannes N Spelbrink, Ian J Holt, Anu Suomalainen. Hum Mol Genet 2004
7
Mammalian transcription factor A is a core component of the mitochondrial transcription machinery.
Yonghong Shi, Anke Dierckx, Paulina H Wanrooij, Sjoerd Wanrooij, Nils-Göran Larsson, L Marcus Wilhelmsson, Maria Falkenberg, Claes M Gustafsson. Proc Natl Acad Sci U S A 2012
Yonghong Shi, Anke Dierckx, Paulina H Wanrooij, Sjoerd Wanrooij, Nils-Göran Larsson, L Marcus Wilhelmsson, Maria Falkenberg, Claes M Gustafsson. Proc Natl Acad Sci U S A 2012
7
7
Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number.
Christopher T Campbell, Jill E Kolesar, Brett A Kaufman. Biochim Biophys Acta 2012
Christopher T Campbell, Jill E Kolesar, Brett A Kaufman. Biochim Biophys Acta 2012
7
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha.
Sibylle Jäger, Christoph Handschin, Julie St-Pierre, Bruce M Spiegelman. Proc Natl Acad Sci U S A 2007
Sibylle Jäger, Christoph Handschin, Julie St-Pierre, Bruce M Spiegelman. Proc Natl Acad Sci U S A 2007
7
Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion.
Ashlee R Stiles, Mariella T Simon, Alexander Stover, Shaya Eftekharian, Negar Khanlou, Hanlin L Wang, Shino Magaki, Hane Lee, Kate Partynski, Nagmeh Dorrani,[...]. Mol Genet Metab 2016
Ashlee R Stiles, Mariella T Simon, Alexander Stover, Shaya Eftekharian, Negar Khanlou, Hanlin L Wang, Shino Magaki, Hane Lee, Kate Partynski, Nagmeh Dorrani,[...]. Mol Genet Metab 2016
11
Mitochondrial DNA in innate immune responses and inflammatory pathology.
A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
A Phillip West, Gerald S Shadel. Nat Rev Immunol 2017
7
ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells.
Samantha C Lewis, Lauren F Uchiyama, Jodi Nunnari. Science 2016
Samantha C Lewis, Lauren F Uchiyama, Jodi Nunnari. Science 2016
7
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
7
Similarity of human mitochondrial transcription factor 1 to high mobility group proteins.
M A Parisi, D A Clayton. Science 1991
M A Parisi, D A Clayton. Science 1991
7
Organization and dynamics of human mitochondrial DNA.
Frédéric Legros, Florence Malka, Paule Frachon, Anne Lombès, Manuel Rojo. J Cell Sci 2004
Frédéric Legros, Florence Malka, Paule Frachon, Anne Lombès, Manuel Rojo. J Cell Sci 2004
7
ER tubules mark sites of mitochondrial division.
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
Jonathan R Friedman, Laura L Lackner, Matthew West, Jared R DiBenedetto, Jodi Nunnari, Gia K Voeltz. Science 2011
7
Purification and characterization of human mitochondrial transcription factor 1.
R P Fisher, D A Clayton. Mol Cell Biol 1988
R P Fisher, D A Clayton. Mol Cell Biol 1988
7
Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis.
J V Virbasius, R C Scarpulla. Proc Natl Acad Sci U S A 1994
J V Virbasius, R C Scarpulla. Proc Natl Acad Sci U S A 1994
7
Mitochondrial DNA replication in mammalian cells: overview of the pathway.
Maria Falkenberg. Essays Biochem 2018
Maria Falkenberg. Essays Biochem 2018
11
Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.
Maria Falkenberg, Martina Gaspari, Anja Rantanen, Aleksandra Trifunovic, Nils-Göran Larsson, Claes M Gustafsson. Nat Genet 2002
Maria Falkenberg, Martina Gaspari, Anja Rantanen, Aleksandra Trifunovic, Nils-Göran Larsson, Claes M Gustafsson. Nat Genet 2002
7
7
Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication.
Javier Miralles Fusté, Sjoerd Wanrooij, Elisabeth Jemt, Caroline E Granycome, Tricia J Cluett, Yonghong Shi, Neli Atanassova, Ian J Holt, Claes M Gustafsson, Maria Falkenberg. Mol Cell 2010
Javier Miralles Fusté, Sjoerd Wanrooij, Elisabeth Jemt, Caroline E Granycome, Tricia J Cluett, Yonghong Shi, Neli Atanassova, Ian J Holt, Claes M Gustafsson, Maria Falkenberg. Mol Cell 2010
6
Reconstitution of a minimal mtDNA replisome in vitro.
Jenny A Korhonen, Xuan Hoi Pham, Mina Pellegrini, Maria Falkenberg. EMBO J 2004
Jenny A Korhonen, Xuan Hoi Pham, Mina Pellegrini, Maria Falkenberg. EMBO J 2004
6
DNA replication and transcription in mammalian mitochondria.
Maria Falkenberg, Nils-Göran Larsson, Claes M Gustafsson. Annu Rev Biochem 2007
Maria Falkenberg, Nils-Göran Larsson, Claes M Gustafsson. Annu Rev Biochem 2007
6
Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells.
Katsumi Kasashima, Megumi Sumitani, Hitoshi Endo. Exp Cell Res 2011
Katsumi Kasashima, Megumi Sumitani, Hitoshi Endo. Exp Cell Res 2011
18
MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins.
Sarah E Calvo, Karl R Clauser, Vamsi K Mootha. Nucleic Acids Res 2016
Sarah E Calvo, Karl R Clauser, Vamsi K Mootha. Nucleic Acids Res 2016
6
Human mitochondrial DNA replication machinery and disease.
Matthew J Young, William C Copeland. Curr Opin Genet Dev 2016
Matthew J Young, William C Copeland. Curr Opin Genet Dev 2016
6
The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions.
Nadee Nissanka, Sandra R Bacman, Melanie J Plastini, Carlos T Moraes. Nat Commun 2018
Nadee Nissanka, Sandra R Bacman, Melanie J Plastini, Carlos T Moraes. Nat Commun 2018
12
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.
Hsiuchen Chen, Marc Vermulst, Yun E Wang, Anne Chomyn, Tomas A Prolla, J Michael McCaffery, David C Chan. Cell 2010
Hsiuchen Chen, Marc Vermulst, Yun E Wang, Anne Chomyn, Tomas A Prolla, J Michael McCaffery, David C Chan. Cell 2010
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.