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Times Cited: 551
Times Cited: 551
Times Cited
Times Co-cited
Similarity
Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice.
N G Larsson, J Wang, H Wilhelmsson, A Oldfors, P Rustin, M Lewandoski, G S Barsh, D A Clayton. Nat Genet 1998
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The mitochondrial transcription factor TFAM coordinates the assembly of multiple DNA molecules into nucleoid-like structures.
Brett A Kaufman, Nela Durisic, Jeffrey M Mativetsky, Santiago Costantino, Mark A Hancock, Peter Grutter, Eric A Shoubridge. Mol Biol Cell 2007
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Human mitochondrial DNA is packaged with TFAM.
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Cross-strand binding of TFAM to a single mtDNA molecule forms the mitochondrial nucleoid.
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Claes M Gustafsson, Maria Falkenberg, Nils-Göran Larsson. Annu Rev Biochem 2016
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Purification and characterization of human mitochondrial transcription factor 1.
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Super-resolution microscopy reveals that mammalian mitochondrial nucleoids have a uniform size and frequently contain a single copy of mtDNA.
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Overexpression of TFAM or twinkle increases mtDNA copy number and facilitates cardioprotection associated with limited mitochondrial oxidative stress.
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Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.
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Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA.
Tomotake Kanki, Kippei Ohgaki, Martina Gaspari, Claes M Gustafsson, Atsushi Fukuoh, Narie Sasaki, Naotaka Hamasaki, Dongchon Kang. Mol Cell Biol 2004
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The mitochondrial transcription and packaging factor Tfam imposes a U-turn on mitochondrial DNA.
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Mitochondrial Lon protease regulates mitochondrial DNA copy number and transcription by selective degradation of mitochondrial transcription factor A (TFAM).
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Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter.
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Mitochondrial transcription factor A (TFAM): roles in maintenance of mtDNA and cellular functions.
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Organization and dynamics of human mitochondrial DNA.
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Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Huu B Ngo, Geoffrey A Lovely, Rob Phillips, David C Chan. Nat Commun 2014
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Alterations to the expression level of mitochondrial transcription factor A, TFAM, modify the mode of mitochondrial DNA replication in cultured human cells.
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Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.
Maria Falkenberg, Martina Gaspari, Anja Rantanen, Aleksandra Trifunovic, Nils-Göran Larsson, Claes M Gustafsson. Nat Genet 2002
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Premature ageing in mice expressing defective mitochondrial DNA polymerase.
Aleksandra Trifunovic, Anna Wredenberg, Maria Falkenberg, Johannes N Spelbrink, Anja T Rovio, Carl E Bruder, Mohammad Bohlooly-Y, Sebastian Gidlöf, Anders Oldfors, Rolf Wibom,[...]. Nature 2004
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Composition and dynamics of human mitochondrial nucleoids.
Nuria Garrido, Lorena Griparic, Eija Jokitalo, Jorma Wartiovaara, Alexander M van der Bliek, Johannes N Spelbrink. Mol Biol Cell 2003
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Mammalian transcription factor A is a core component of the mitochondrial transcription machinery.
Yonghong Shi, Anke Dierckx, Paulina H Wanrooij, Sjoerd Wanrooij, Nils-Göran Larsson, L Marcus Wilhelmsson, Maria Falkenberg, Claes M Gustafsson. Proc Natl Acad Sci U S A 2012
Yonghong Shi, Anke Dierckx, Paulina H Wanrooij, Sjoerd Wanrooij, Nils-Göran Larsson, L Marcus Wilhelmsson, Maria Falkenberg, Claes M Gustafsson. Proc Natl Acad Sci U S A 2012
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Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number.
Christopher T Campbell, Jill E Kolesar, Brett A Kaufman. Biochim Biophys Acta 2012
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Similarity of human mitochondrial transcription factor 1 to high mobility group proteins.
M A Parisi, D A Clayton. Science 1991
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In vitro-reconstituted nucleoids can block mitochondrial DNA replication and transcription.
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Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.
Sandra R Bacman, Siôn L Williams, Milena Pinto, Susana Peralta, Carlos T Moraes. Nat Med 2013
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Number matters: control of mammalian mitochondrial DNA copy number.
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Superresolution fluorescence imaging of mitochondrial nucleoids reveals their spatial range, limits, and membrane interaction.
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The mitochondrial nucleoid: integrating mitochondrial DNA into cellular homeostasis.
Robert Gilkerson, Liliana Bravo, Iraselia Garcia, Norma Gaytan, Alan Herrera, Alicia Maldonado, Brandi Quintanilla. Cold Spring Harb Perspect Biol 2013
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Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number.
Henna Tyynismaa, Hiroshi Sembongi, Monika Bokori-Brown, Caroline Granycome, Neil Ashley, Joanna Poulton, Anu Jalanko, Johannes N Spelbrink, Ian J Holt, Anu Suomalainen. Hum Mol Genet 2004
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Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.
Yun E Wang, Georgi K Marinov, Barbara J Wold, David C Chan. PLoS One 2013
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Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein.
Chihiro Takamatsu, Shuyo Umeda, Takashi Ohsato, Tetsuji Ohno, Yoshito Abe, Atsushi Fukuoh, Hideo Shinagawa, Naotaka Hamasaki, Dongchon Kang. EMBO Rep 2002
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The functional organization of mitochondrial genomes in human cells.
Francisco J Iborra, Hiroshi Kimura, Peter R Cook. BMC Biol 2004
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The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms.
Inhae Kang, Charleen T Chu, Brett A Kaufman. FEBS Lett 2018
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Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo.
Payam A Gammage, Carlo Viscomi, Marie-Lune Simard, Ana S H Costa, Edoardo Gaude, Christopher A Powell, Lindsey Van Haute, Beverly J McCann, Pedro Rebelo-Guiomar, Raffaele Cerutti,[...]. Nat Med 2018
Payam A Gammage, Carlo Viscomi, Marie-Lune Simard, Ana S H Costa, Edoardo Gaude, Christopher A Powell, Lindsey Van Haute, Beverly J McCann, Pedro Rebelo-Guiomar, Raffaele Cerutti,[...]. Nat Med 2018
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Increased Total mtDNA Copy Number Cures Male Infertility Despite Unaltered mtDNA Mutation Load.
Min Jiang, Timo Eino Sakari Kauppila, Elisa Motori, Xinping Li, Ilian Atanassov, Kat Folz-Donahue, Nina Anna Bonekamp, Sara Albarran-Gutierrez, James Bruce Stewart, Nils-Göran Larsson. Cell Metab 2017
Min Jiang, Timo Eino Sakari Kauppila, Elisa Motori, Xinping Li, Ilian Atanassov, Kat Folz-Donahue, Nina Anna Bonekamp, Sara Albarran-Gutierrez, James Bruce Stewart, Nils-Göran Larsson. Cell Metab 2017
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Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Payam A Gammage, Joanna Rorbach, Anna I Vincent, Edward J Rebar, Michal Minczuk. EMBO Mol Med 2014
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MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation.
Sandra R Bacman, Johanna H K Kauppila, Claudia V Pereira, Nadee Nissanka, Maria Miranda, Milena Pinto, Sion L Williams, Nils-Göran Larsson, James B Stewart, Carlos T Moraes. Nat Med 2018
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Selective elimination of mitochondrial mutations in the germline by genome editing.
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Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators.
Natalie Gleyzer, Kristel Vercauteren, Richard C Scarpulla. Mol Cell Biol 2005
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Mutations in TFAM, encoding mitochondrial transcription factor A, cause neonatal liver failure associated with mtDNA depletion.
Ashlee R Stiles, Mariella T Simon, Alexander Stover, Shaya Eftekharian, Negar Khanlou, Hanlin L Wang, Shino Magaki, Hane Lee, Kate Partynski, Nagmeh Dorrani,[...]. Mol Genet Metab 2016
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11
Mitochondrial DNA stress primes the antiviral innate immune response.
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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis.
Kate McArthur, Lachlan W Whitehead, John M Heddleston, Lucy Li, Benjamin S Padman, Viola Oorschot, Niall D Geoghegan, Stephane Chappaz, Sophia Davidson, Hui San Chin,[...]. Science 2018
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The layered structure of human mitochondrial DNA nucleoids.
Daniel F Bogenhagen, Denis Rousseau, Stephanie Burke. J Biol Chem 2008
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Human mitochondrial RNA polymerase primes lagging-strand DNA synthesis in vitro.
Sjoerd Wanrooij, Javier Miralles Fusté, Géraldine Farge, Yonghong Shi, Claes M Gustafsson, Maria Falkenberg. Proc Natl Acad Sci U S A 2008
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Increased mitochondrial mass in mitochondrial myopathy mice.
Anna Wredenberg, Rolf Wibom, Hans Wilhelmsson, Caroline Graff, Heidi H Wiener, Steven J Burden, Anders Oldfors, Håkan Westerblad, Nils-Göran Larsson. Proc Natl Acad Sci U S A 2002
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The Role of Exercise and TFAM in Preventing Skeletal Muscle Atrophy.
Nicholas T Theilen, George H Kunkel, Suresh C Tyagi. J Cell Physiol 2017
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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1.
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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease.
Alicia M Pickrell, Richard J Youle. Neuron 2015
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MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.
Aindrila Chatterjee, Janine Seyfferth, Jacopo Lucci, Ralf Gilsbach, Sebastian Preissl, Lena Böttinger, Christoph U Mårtensson, Amol Panhale, Thomas Stehle, Oliver Kretz,[...]. Cell 2016
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8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.