A citation-based method for searching scientific literature

Tom Stiff, Mark O'Driscoll, Nicole Rief, Kuniyoshi Iwabuchi, Markus Löbrich, Penny A Jeggo. Cancer Res 2004
Times Cited: 757







List of co-cited articles
1067 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
37

ATM phosphorylates histone H2AX in response to DNA double-strand breaks.
S Burma, B P Chen, M Murphy, A Kurimasa, D J Chen. J Biol Chem 2001
32


The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
19

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
764
19


Megabase chromatin domains involved in DNA double-strand breaks in vivo.
E P Rogakou, C Boon, C Redon, W M Bonner. J Cell Biol 1999
15

The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
14

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, E Robert McDonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal,[...]. Science 2007
13

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks.
Arkady Celeste, Oscar Fernandez-Capetillo, Michael J Kruhlak, Duane R Pilch, David W Staudt, Alicia Lee, Robert F Bonner, William M Bonner, André Nussenzweig. Nat Cell Biol 2003
757
12

Genomic instability in mice lacking histone H2AX.
Arkady Celeste, Simone Petersen, Peter J Romanienko, Oscar Fernandez-Capetillo, Hua Tang Chen, Olga A Sedelnikova, Bernardo Reina-San-Martin, Vincenzo Coppola, Eric Meffre, Michael J Difilippantonio,[...]. Science 2002
11

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
Manuel Stucki, Julie A Clapperton, Duaa Mohammad, Michael B Yaffe, Stephen J Smerdon, Stephen P Jackson. Cell 2005
759
11

Requirement of the MRN complex for ATM activation by DNA damage.
Tamar Uziel, Yaniv Lerenthal, Lilach Moyal, Yair Andegeko, Leonid Mittelman, Yosef Shiloh. EMBO J 2003
781
11

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.
Amélie Fradet-Turcotte, Marella D Canny, Cristina Escribano-Díaz, Alexandre Orthwein, Charles C Y Leung, Hao Huang, Marie-Claude Landry, Julianne Kitevski-LeBlanc, Sylvie M Noordermeer, Frank Sicheri,[...]. Nature 2013
439
10

RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling.
Francesca Mattiroli, Joseph H A Vissers, Willem J van Dijk, Pauline Ikpa, Elisabetta Citterio, Wim Vermeulen, Jurgen A Marteijn, Titia K Sixma. Cell 2012
404
10



Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
10

The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
Grant S Stewart, Stephanie Panier, Kelly Townsend, Abdallah K Al-Hakim, Nadine K Kolas, Edward S Miller, Shinichiro Nakada, Jarkko Ylanko, Signe Olivarius, Megan Mendez,[...]. Cell 2009
549
9

RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.
Niels Mailand, Simon Bekker-Jensen, Helene Faustrup, Fredrik Melander, Jiri Bartek, Claudia Lukas, Jiri Lukas. Cell 2007
854
9

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Jacob Falck, Julia Coates, Stephen P Jackson. Nature 2005
921
9

Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
662
9

DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
382
9

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
Tina Thorslund, Anita Ripplinger, Saskia Hoffmann, Thomas Wild, Michael Uckelmann, Bine Villumsen, Takeo Narita, Titia K Sixma, Chunaram Choudhary, Simon Bekker-Jensen,[...]. Nature 2015
232
8

RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
Michael S Y Huen, Robert Grant, Isaac Manke, Kay Minn, Xiaochun Yu, Michael B Yaffe, Junjie Chen. Cell 2007
780
8



Double-strand break repair: 53BP1 comes into focus.
Stephanie Panier, Simon J Boulton. Nat Rev Mol Cell Biol 2014
622
8

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
Enriqueta Riballo, Martin Kühne, Nicole Rief, Aidan Doherty, Graeme C M Smith, María-José Recio, Caroline Reis, Kirsten Dahm, Andreas Fricke, Andrea Krempler,[...]. Mol Cell 2004
662
8

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.
T T Paull, E P Rogakou, V Yamazaki, C U Kirchgessner, M Gellert, W M Bonner. Curr Biol 2000
8

Repair Pathway Choices and Consequences at the Double-Strand Break.
Raphael Ceccaldi, Beatrice Rondinelli, Alan D D'Andrea. Trends Cell Biol 2016
727
8

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks.
François Aymard, Beatrix Bugler, Christine K Schmidt, Emmanuelle Guillou, Pierre Caron, Sébastien Briois, Jason S Iacovoni, Virginie Daburon, Kyle M Miller, Stephen P Jackson,[...]. Nat Struct Mol Biol 2014
371
7

RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.
Carsten Doil, Niels Mailand, Simon Bekker-Jensen, Patrice Menard, Dorthe Helena Larsen, Rainer Pepperkok, Jan Ellenberg, Stephanie Panier, Daniel Durocher, Jiri Bartek,[...]. Cell 2009
655
7

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair.
Maria Victoria Botuyan, Joseph Lee, Irene M Ward, Ja-Eun Kim, James R Thompson, Junjie Chen, Georges Mer. Cell 2006
712
7

Histone H2A.Z controls a critical chromatin remodeling step required for DNA double-strand break repair.
Ye Xu, Marina K Ayrapetov, Chang Xu, Ozge Gursoy-Yuzugullu, Yiduo Hu, Brendan D Price. Mol Cell 2012
204
7

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM.
Ian Hickson, Yan Zhao, Caroline J Richardson, Sharon J Green, Niall M B Martin, Alisdair I Orr, Philip M Reaper, Stephen P Jackson, Nicola J Curtin, Graeme C M Smith. Cancer Res 2004
931
7

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
7


The DNA damage response: ten years after.
J Wade Harper, Stephen J Elledge. Mol Cell 2007
7

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.
Benjamin P C Chen, Naoya Uematsu, Junya Kobayashi, Yaniv Lerenthal, Andrea Krempler, Hirohiko Yajima, Markus Löbrich, Yosef Shiloh, David J Chen. J Biol Chem 2007
225
7

ATR: an essential regulator of genome integrity.
Karlene A Cimprich, David Cortez. Nat Rev Mol Cell Biol 2008
7

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
7

Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.
Kenta Yamamoto, Yunyue Wang, Wenxia Jiang, Xiangyu Liu, Richard L Dubois, Chyuan-Sheng Lin, Thomas Ludwig, Christopher J Bakkenist, Shan Zha. J Cell Biol 2012
87
8

A single ataxia telangiectasia gene with a product similar to PI-3 kinase.
K Savitsky, A Bar-Shira, S Gilad, G Rotman, Y Ziv, L Vanagaite, D A Tagle, S Smith, T Uziel, S Sfez,[...]. Science 1995
7

DNA damage sensing by the ATM and ATR kinases.
Alexandre Maréchal, Lee Zou. Cold Spring Harb Perspect Biol 2013
707
7

PARP inhibitors: Synthetic lethality in the clinic.
Christopher J Lord, Alan Ashworth. Science 2017
7


A macrohistone variant links dynamic chromatin compaction to BRCA1-dependent genome maintenance.
Simran Khurana, Michael J Kruhlak, Jeongkyu Kim, Andy D Tran, Jinping Liu, Katherine Nyswaner, Lei Shi, Parthav Jailwala, Myong-Hee Sung, Ofir Hakim,[...]. Cell Rep 2014
139
6

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.
Andrew Xiao, Haitao Li, David Shechter, Sung Hee Ahn, Laura A Fabrizio, Hediye Erdjument-Bromage, Satoko Ishibe-Murakami, Bin Wang, Paul Tempst, Kay Hofmann,[...]. Nature 2009
288
6

Mechanisms of ATM Activation.
Tanya T Paull. Annu Rev Biochem 2015
268
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.