P Hemachandra Reddy, Shannon McWeeney, Byung S Park, Maria Manczak, Ramana V Gutala, Dara Partovi, Youngsin Jung, Vincent Yau, Robert Searles, Motomi Mori, Joseph Quinn. Hum Mol Genet 2004
Times Cited: 242
Times Cited: 242
Times Cited
Times Co-cited
Similarity
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
Maria Manczak, Thimmappa S Anekonda, Edward Henson, Byung S Park, Joseph Quinn, P Hemachandra Reddy. Hum Mol Genet 2006
41
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease.
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
Xinglong Wang, Bo Su, Hyoung-gon Lee, Xinyi Li, George Perry, Mark A Smith, Xiongwei Zhu. J Neurosci 2009
33
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
Maria Manczak, Marcus J Calkins, P Hemachandra Reddy. Hum Mol Genet 2011
33
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins.
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
Xinglong Wang, Bo Su, Sandra L Siedlak, Paula I Moreira, Hisashi Fujioka, Yang Wang, Gemma Casadesus, Xiongwei Zhu. Proc Natl Acad Sci U S A 2008
28
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease.
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
P Hemachandra Reddy, M Flint Beal. Trends Mol Med 2008
28
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
Casper Caspersen, Ning Wang, Jun Yao, Alexander Sosunov, Xi Chen, Joyce W Lustbader, Hong Wei Xu, David Stern, Guy McKhann, Shi Du Yan. FASEB J 2005
27
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
Latha Devi, Badanavalu M Prabhu, Domenico F Galati, Narayan G Avadhani, Hindupur K Anandatheerthavarada. J Neurosci 2006
27
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
26
Mitochondrial abnormalities in Alzheimer's disease.
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
K Hirai, G Aliev, A Nunomura, H Fujioka, R L Russell, C S Atwood, A B Johnson, Y Kress, H V Vinters, M Tabaton,[...]. J Neurosci 2001
24
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics.
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
P Hemachandra Reddy, Raghav Tripathi, Quang Troung, Karuna Tirumala, Tejaswini P Reddy, Vishwanath Anekonda, Ulziibat P Shirendeb, Marcus J Calkins, Arubala P Reddy, Peizhong Mao,[...]. Biochim Biophys Acta 2012
24
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease.
Jia Yao, Ronald W Irwin, Liqin Zhao, Jon Nilsen, Ryan T Hamilton, Roberta Diaz Brinton. Proc Natl Acad Sci U S A 2009
Jia Yao, Ronald W Irwin, Liqin Zhao, Jon Nilsen, Ryan T Hamilton, Roberta Diaz Brinton. Proc Natl Acad Sci U S A 2009
24
Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.
Maria Manczak, Byung S Park, Youngsin Jung, P Hemachandra Reddy. Neuromolecular Med 2004
Maria Manczak, Byung S Park, Youngsin Jung, P Hemachandra Reddy. Neuromolecular Med 2004
24
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
Marcus J Calkins, Maria Manczak, Peizhong Mao, Ulziibat Shirendeb, P Hemachandra Reddy. Hum Mol Genet 2011
22
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
Joyce W Lustbader, Maurizio Cirilli, Chang Lin, Hong Wei Xu, Kazuhiro Takuma, Ning Wang, Casper Caspersen, Xi Chen, Susan Pollak, Michael Chaney,[...]. Science 2004
22
Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons.
Maria Manczak, Peizhong Mao, Marcus J Calkins, Anda Cornea, Arubala P Reddy, Michael P Murphy, Hazel H Szeto, Byung Park, P Hemachandra Reddy. J Alzheimers Dis 2010
Maria Manczak, Peizhong Mao, Marcus J Calkins, Anda Cornea, Arubala P Reddy, Michael P Murphy, Hazel H Szeto, Byung Park, P Hemachandra Reddy. J Alzheimers Dis 2010
21
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease.
Heng Du, Lan Guo, Fang Fang, Doris Chen, Alexander A Sosunov, Guy M McKhann, Yilin Yan, Chunyu Wang, Hong Zhang, Jeffery D Molkentin,[...]. Nat Med 2008
Heng Du, Lan Guo, Fang Fang, Doris Chen, Alexander A Sosunov, Guy M McKhann, Yilin Yan, Chunyu Wang, Hong Zhang, Jeffery D Molkentin,[...]. Nat Med 2008
20
A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.
I Maurer, S Zierz, H J Möller. Neurobiol Aging 2000
I Maurer, S Zierz, H J Möller. Neurobiol Aging 2000
19
A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease.
Russell H Swerdlow, Shaharyar M Khan. Med Hypotheses 2004
Russell H Swerdlow, Shaharyar M Khan. Med Hypotheses 2004
18
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.
Peter J Crouch, Rachel Blake, James A Duce, Giuseppe D Ciccotosto, Qiao-Xin Li, Kevin J Barnham, Cyril C Curtain, Robert A Cherny, Roberto Cappai, Thomas Dyrks,[...]. J Neurosci 2005
Peter J Crouch, Rachel Blake, James A Duce, Giuseppe D Ciccotosto, Qiao-Xin Li, Kevin J Barnham, Cyril C Curtain, Robert A Cherny, Roberto Cappai, Thomas Dyrks,[...]. J Neurosci 2005
17
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model.
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
Heng Du, Lan Guo, Shiqiang Yan, Alexander A Sosunov, Guy M McKhann, Shirley ShiDu Yan. Proc Natl Acad Sci U S A 2010
17
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.
Michael T Lin, M Flint Beal. Nature 2006
Michael T Lin, M Flint Beal. Nature 2006
17
Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease.
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
Maria Manczak, P Hemachandra Reddy. Hum Mol Genet 2012
15
Abnormalities of mitochondrial enzymes in Alzheimer disease.
G E Gibson, K F Sheu, J P Blass. J Neural Transm (Vienna) 1998
G E Gibson, K F Sheu, J P Blass. J Neural Transm (Vienna) 1998
14
Oxidative damage is the earliest event in Alzheimer disease.
A Nunomura, G Perry, G Aliev, K Hirai, A Takeda, E K Balraj, P K Jones, H Ghanbari, T Wataya, S Shimohama,[...]. J Neuropathol Exp Neurol 2001
A Nunomura, G Perry, G Aliev, K Hirai, A Takeda, E K Balraj, P K Jones, H Ghanbari, T Wataya, S Shimohama,[...]. J Neuropathol Exp Neurol 2001
14
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities.
C S Casley, L Canevari, J M Land, J B Clark, M A Sharpe. J Neurochem 2002
C S Casley, L Canevari, J M Land, J B Clark, M A Sharpe. J Neurochem 2002
14
Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice.
Virginie Rhein, Xiaomin Song, Andreas Wiesner, Lars M Ittner, Ginette Baysang, Fides Meier, Laurence Ozmen, Horst Bluethmann, Stefan Dröse, Ulrich Brandt,[...]. Proc Natl Acad Sci U S A 2009
Virginie Rhein, Xiaomin Song, Andreas Wiesner, Lars M Ittner, Ginette Baysang, Fides Meier, Laurence Ozmen, Horst Bluethmann, Stefan Dröse, Ulrich Brandt,[...]. Proc Natl Acad Sci U S A 2009
14
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
Camilla A Hansson Petersen, Nyosha Alikhani, Homira Behbahani, Birgitta Wiehager, Pavel F Pavlov, Irina Alafuzoff, Ville Leinonen, Akira Ito, Bengt Winblad, Elzbieta Glaser,[...]. Proc Natl Acad Sci U S A 2008
13
Cytochrome oxidase deficiency in Alzheimer's disease.
W D Parker, C M Filley, J K Parks. Neurology 1990
W D Parker, C M Filley, J K Parks. Neurology 1990
13
Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline.
P Hemachandra Reddy, Maria Manczak, Peizhong Mao, Marcus J Calkins, Arubala P Reddy, Ulziibat Shirendeb. J Alzheimers Dis 2010
P Hemachandra Reddy, Maria Manczak, Peizhong Mao, Marcus J Calkins, Arubala P Reddy, Ulziibat Shirendeb. J Alzheimers Dis 2010
13
Oxidative damage in Alzheimer's.
M A Smith, G Perry, P L Richey, L M Sayre, V E Anderson, M F Beal, N Kowall. Nature 1996
M A Smith, G Perry, P L Richey, L M Sayre, V E Anderson, M F Beal, N Kowall. Nature 1996
13
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics.
John Hardy, Dennis J Selkoe. Science 2002
John Hardy, Dennis J Selkoe. Science 2002
13
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.
D Praticò, K Uryu, S Leight, J Q Trojanoswki, V M Lee. J Neurosci 2001
D Praticò, K Uryu, S Leight, J Q Trojanoswki, V M Lee. J Neurosci 2001
12
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
Salvatore Oddo, Antonella Caccamo, Jason D Shepherd, M Paul Murphy, Todd E Golde, Rakez Kayed, Raju Metherate, Mark P Mattson, Yama Akbari, Frank M LaFerla. Neuron 2003
Salvatore Oddo, Antonella Caccamo, Jason D Shepherd, M Paul Murphy, Todd E Golde, Rakez Kayed, Raju Metherate, Mark P Mattson, Yama Akbari, Frank M LaFerla. Neuron 2003
12
Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.
Xiongwei Zhu, George Perry, Mark A Smith, Xinglong Wang. J Alzheimers Dis 2013
Xiongwei Zhu, George Perry, Mark A Smith, Xinglong Wang. J Alzheimers Dis 2013
12
Amyloid precursor protein-mediated free radicals and oxidative damage: implications for the development and progression of Alzheimer's disease.
P Hemachandra Reddy. J Neurochem 2006
P Hemachandra Reddy. J Neurochem 2006
12
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
Ulziibat Shirendeb, Arubala P Reddy, Maria Manczak, Marcus J Calkins, Peizhong Mao, Danilo A Tagle, P Hemachandra Reddy. Hum Mol Genet 2011
12
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients.
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
Xinglong Wang, Bo Su, Hisashi Fujioka, Xiongwei Zhu. Am J Pathol 2008
11
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses.
Zheng Li, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng. Cell 2004
Zheng Li, Ken-Ichi Okamoto, Yasunori Hayashi, Morgan Sheng. Cell 2004
11
The Alzheimer's disease mitochondrial cascade hypothesis.
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. J Alzheimers Dis 2010
Russell H Swerdlow, Jeffrey M Burns, Shaharyar M Khan. J Alzheimers Dis 2010
11
Soluble beta-amyloid leads to mitochondrial defects in amyloid precursor protein and tau transgenic mice.
Anne Eckert, Susanne Hauptmann, Isabel Scherping, Virginie Rhein, Franz Müller-Spahn, Jürgen Götz, Walter E Müller. Neurodegener Dis 2008
Anne Eckert, Susanne Hauptmann, Isabel Scherping, Virginie Rhein, Franz Müller-Spahn, Jürgen Götz, Walter E Müller. Neurodegener Dis 2008
11
Intracellular amyloid-beta in Alzheimer's disease.
Frank M LaFerla, Kim N Green, Salvatore Oddo. Nat Rev Neurosci 2007
Frank M LaFerla, Kim N Green, Salvatore Oddo. Nat Rev Neurosci 2007
11
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication.
Pinar E Coskun, M Flint Beal, Douglas C Wallace. Proc Natl Acad Sci U S A 2004
Pinar E Coskun, M Flint Beal, Douglas C Wallace. Proc Natl Acad Sci U S A 2004
11
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease.
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
Xinglong Wang, Wenzhang Wang, Li Li, George Perry, Hyoung-gon Lee, Xiongwei Zhu. Biochim Biophys Acta 2014
11
Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease.
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
Maria Manczak, Ramesh Kandimalla, Xiangling Yin, P Hemachandra Reddy. Hum Mol Genet 2018
11
Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease.
P Hemachandra Reddy. Exp Neurol 2009
P Hemachandra Reddy. Exp Neurol 2009
10
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice.
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
S Hauptmann, I Scherping, S Dröse, U Brandt, K L Schulz, M Jendrach, K Leuner, A Eckert, W E Müller. Neurobiol Aging 2009
10
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease.
Eugenia Trushina, Emirhan Nemutlu, Song Zhang, Trace Christensen, Jon Camp, Janny Mesa, Ammar Siddiqui, Yasushi Tamura, Hiromi Sesaki, Thomas M Wengenack,[...]. PLoS One 2012
Eugenia Trushina, Emirhan Nemutlu, Song Zhang, Trace Christensen, Jon Camp, Janny Mesa, Ammar Siddiqui, Yasushi Tamura, Hiromi Sesaki, Thomas M Wengenack,[...]. PLoS One 2012
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.