Yuval Dor, Juliana Brown, Olga I Martinez, Douglas A Melton. Nature 2004
Times Cited: 1698
Times Cited: 1698
Times Cited
Times Co-cited
Similarity
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss.
Fabrizio Thorel, Virginie Népote, Isabelle Avril, Kenji Kohno, Renaud Desgraz, Simona Chera, Pedro L Herrera. Nature 2010
Fabrizio Thorel, Virginie Népote, Isabelle Avril, Kenji Kohno, Renaud Desgraz, Simona Chera, Pedro L Herrera. Nature 2010
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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas.
Xiaobo Xu, Joke D'Hoker, Geert Stangé, Stefan Bonné, Nico De Leu, Xiangwei Xiao, Mark Van de Casteele, Georg Mellitzer, Zhidong Ling, Danny Pipeleers,[...]. Cell 2008
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Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.
Simona Chera, Delphine Baronnier, Luiza Ghila, Valentina Cigliola, Jan N Jensen, Guoqiang Gu, Kenichiro Furuyama, Fabrizio Thorel, Fiona M Gribble, Frank Reimann,[...]. Nature 2014
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Generation of functional human pancreatic β cells in vitro.
Felicia W Pagliuca, Jeffrey R Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer Hyoje Ryu, Quinn P Peterson, Dale Greiner, Douglas A Melton. Cell 2014
Felicia W Pagliuca, Jeffrey R Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer Hyoje Ryu, Quinn P Peterson, Dale Greiner, Douglas A Melton. Cell 2014
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Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.
Chutima Talchai, Shouhong Xuan, Hua V Lin, Lori Sussel, Domenico Accili. Cell 2012
Chutima Talchai, Shouhong Xuan, Hua V Lin, Lori Sussel, Domenico Accili. Cell 2012
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Growth and regeneration of adult beta cells does not involve specialized progenitors.
Monica Teta, Matthew M Rankin, Simon Y Long, Geneva M Stein, Jake A Kushner. Dev Cell 2007
Monica Teta, Matthew M Rankin, Simon Y Long, Geneva M Stein, Jake A Kushner. Dev Cell 2007
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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells.
Qiao Zhou, Juliana Brown, Andrew Kanarek, Jayaraj Rajagopal, Douglas A Melton. Nature 2008
Qiao Zhou, Juliana Brown, Andrew Kanarek, Jayaraj Rajagopal, Douglas A Melton. Nature 2008
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Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.
Janel L Kopp, Claire L Dubois, Ashleigh E Schaffer, Ergeng Hao, Hung Ping Shih, Philip A Seymour, Jenny Ma, Maike Sander. Development 2011
Janel L Kopp, Claire L Dubois, Ashleigh E Schaffer, Ergeng Hao, Hung Ping Shih, Philip A Seymour, Jenny Ma, Maike Sander. Development 2011
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Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth.
Akari Inada, Cameron Nienaber, Hitoshi Katsuta, Yoshio Fujitani, Jared Levine, Rina Morita, Arun Sharma, Susan Bonner-Weir. Proc Natl Acad Sci U S A 2008
Akari Inada, Cameron Nienaber, Hitoshi Katsuta, Yoshio Fujitani, Jared Levine, Rina Morita, Arun Sharma, Susan Bonner-Weir. Proc Natl Acad Sci U S A 2008
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Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans.
Juris J Meier, Alexandra E Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A Rizza, Peter C Butler. Diabetes 2008
Juris J Meier, Alexandra E Butler, Yoshifumi Saisho, Travis Monchamp, Ryan Galasso, Anil Bhushan, Robert A Rizza, Peter C Butler. Diabetes 2008
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Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells.
Alireza Rezania, Jennifer E Bruin, Payal Arora, Allison Rubin, Irina Batushansky, Ali Asadi, Shannon O'Dwyer, Nina Quiskamp, Majid Mojibian, Tobias Albrecht,[...]. Nat Biotechnol 2014
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Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
Talitha van der Meulen, Alex M Mawla, Michael R DiGruccio, Michael W Adams, Vera Nies, Sophie Dólleman, Siming Liu, Amanda M Ackermann, Elena Cáceres, Anna E Hunter,[...]. Cell Metab 2017
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Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes.
Cristina Aguayo-Mazzucato, Susan Bonner-Weir. Cell Metab 2018
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A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.
Peng Wang, Juan-Carlos Alvarez-Perez, Dan P Felsenfeld, Hongtao Liu, Sharmila Sivendran, Aaron Bender, Anil Kumar, Roberto Sanchez, Donald K Scott, Adolfo Garcia-Ocaña,[...]. Nat Med 2015
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Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes.
Alexandra E Butler, Juliette Janson, Susan Bonner-Weir, Robert Ritzel, Robert A Rizza, Peter C Butler. Diabetes 2003
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Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells.
Kenichiro Furuyama, Simona Chera, Léon van Gurp, Daniel Oropeza, Luiza Ghila, Nicolas Damond, Heidrun Vethe, Joao A Paulo, Antoinette M Joosten, Thierry Berney,[...]. Nature 2019
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Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors.
Daisong Wang, Jingqiang Wang, Lanyue Bai, Hong Pan, Hua Feng, Hans Clevers, Yi Arial Zeng. Cell 2020
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Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth.
Myriam Solar, Carina Cardalda, Isabelle Houbracken, Mercè Martín, Miguel Angel Maestro, Nele De Medts, Xiaobo Xu, Vanessa Grau, Harry Heimberg, Luc Bouwens,[...]. Dev Cell 2009
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Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo.
Evert Kroon, Laura A Martinson, Kuniko Kadoya, Anne G Bang, Olivia G Kelly, Susan Eliazer, Holly Young, Mike Richardson, Nora G Smart, Justine Cunningham,[...]. Nat Biotechnol 2008
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Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes.
Francesca Cinti, Ryotaro Bouchi, Ja Young Kim-Muller, Yoshiaki Ohmura, P R Sandoval, Matilde Masini, Lorella Marselli, Mara Suleiman, Lloyd E Ratner, Piero Marchetti,[...]. J Clin Endocrinol Metab 2016
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Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy.
A E Butler, L Cao-Minh, R Galasso, R A Rizza, A Corradin, C Cobelli, P C Butler. Diabetologia 2010
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Charting cellular identity during human in vitro β-cell differentiation.
Adrian Veres, Aubrey L Faust, Henry L Bushnell, Elise N Engquist, Jennifer Hyoje-Ryu Kenty, George Harb, Yeh-Chuin Poh, Elad Sintov, Mads Gürtler, Felicia W Pagliuca,[...]. Nature 2019
Adrian Veres, Aubrey L Faust, Henry L Bushnell, Elise N Engquist, Jennifer Hyoje-Ryu Kenty, George Harb, Yeh-Chuin Poh, Elad Sintov, Mads Gürtler, Felicia W Pagliuca,[...]. Nature 2019
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Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells.
Kevin A D'Amour, Anne G Bang, Susan Eliazer, Olivia G Kelly, Alan D Agulnick, Nora G Smart, Mark A Moorman, Evert Kroon, Melissa K Carpenter, Emmanuel E Baetge. Nat Biotechnol 2006
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Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro.
Holger A Russ, Audrey V Parent, Jennifer J Ringler, Thomas G Hennings, Gopika G Nair, Mayya Shveygert, Tingxia Guo, Sapna Puri, Leena Haataja, Vincenzo Cirulli,[...]. EMBO J 2015
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No evidence for β cell neogenesis in murine adult pancreas.
Xiangwei Xiao, Zean Chen, Chiyo Shiota, Krishna Prasadan, Ping Guo, Yousef El-Gohary, Jose Paredes, Carey Welsh, John Wiersch, George K Gittes. J Clin Invest 2013
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Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Åsa Segerstolpe, Athanasia Palasantza, Pernilla Eliasson, Eva-Marie Andersson, Anne-Christine Andréasson, Xiaoyan Sun, Simone Picelli, Alan Sabirsh, Maryam Clausen, Magnus K Bjursell,[...]. Cell Metab 2016
Åsa Segerstolpe, Athanasia Palasantza, Pernilla Eliasson, Eva-Marie Andersson, Anne-Christine Andréasson, Xiaoyan Sun, Simone Picelli, Alan Sabirsh, Maryam Clausen, Magnus K Bjursell,[...]. Cell Metab 2016
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Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.
Senta Georgia, Anil Bhushan. J Clin Invest 2004
Senta Georgia, Anil Bhushan. J Clin Invest 2004
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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Guoqiang Gu, Jolanta Dubauskaite, Douglas A Melton. Development 2002
Guoqiang Gu, Jolanta Dubauskaite, Douglas A Melton. Development 2002
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Duct cells contribute to regeneration of endocrine and acinar cells following pancreatic damage in adult mice.
Angela Criscimanna, Julie A Speicher, Golbahar Houshmand, Chiyo Shiota, Krishna Prasadan, Baoan Ji, Craig D Logsdon, George K Gittes, Farzad Esni. Gastroenterology 2011
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Spatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.
Fong Cheng Pan, Eric D Bankaitis, Daniel Boyer, Xiaobo Xu, Mark Van de Casteele, Mark A Magnuson, Harry Heimberg, Christopher V E Wright. Development 2013
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Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.
Keith Al-Hasani, Anja Pfeifer, Monica Courtney, Nouha Ben-Othman, Elisabet Gjernes, Andhira Vieira, Noémie Druelle, Fabio Avolio, Philippe Ravassard, Gunter Leuckx,[...]. Dev Cell 2013
Keith Al-Hasani, Anja Pfeifer, Monica Courtney, Nouha Ben-Othman, Elisabet Gjernes, Andhira Vieira, Noémie Druelle, Fabio Avolio, Philippe Ravassard, Gunter Leuckx,[...]. Dev Cell 2013
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Recovery from diabetes in mice by beta cell regeneration.
Tomer Nir, Douglas A Melton, Yuval Dor. J Clin Invest 2007
Tomer Nir, Douglas A Melton, Yuval Dor. J Clin Invest 2007
10
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation.
Weijun Shen, Brandon Taylor, Qihui Jin, Van Nguyen-Tran, Shelly Meeusen, You-Qing Zhang, Anwesh Kamireddy, Austin Swafford, Andrew F Powers, John Walker,[...]. Nat Commun 2015
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Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Ercument Dirice, Deepika Walpita, Amedeo Vetere, Bennett C Meier, Sevim Kahraman, Jiang Hu, Vlado Dančík, Sean M Burns, Tamara J Gilbert, David E Olson,[...]. Diabetes 2016
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Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Peng Wang, Esra Karakose, Hongtao Liu, Ethan Swartz, Courtney Ackeifi, Viktor Zlatanic, Jessica Wilson, Bryan J González, Aaron Bender, Karen K Takane,[...]. Cell Metab 2019
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A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.
Maayan Baron, Adrian Veres, Samuel L Wolock, Aubrey L Faust, Renaud Gaujoux, Amedeo Vetere, Jennifer Hyoje Ryu, Bridget K Wagner, Shai S Shen-Orr, Allon M Klein,[...]. Cell Syst 2016
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Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreas.
Meritxell Rovira, Sherri-Gae Scott, Andrew S Liss, Jan Jensen, Sarah P Thayer, Steven D Leach. Proc Natl Acad Sci U S A 2010
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Pancreatic Progenitors: There and Back Again.
Juan Domínguez-Bendala, Mirza Muhammad Fahd Qadir, Ricardo Luis Pastori. Trends Endocrinol Metab 2019
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The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais,[...]. PLoS Genet 2013
Monica Courtney, Elisabet Gjernes, Noémie Druelle, Christophe Ravaud, Andhira Vieira, Nouha Ben-Othman, Anja Pfeifer, Fabio Avolio, Gunter Leuckx, Sandra Lacas-Gervais,[...]. PLoS Genet 2013
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Pancreatic β cell dedifferentiation in diabetes and redifferentiation following insulin therapy.
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Pancreatic β-cell proliferation in obesity.
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PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum.
M F Offield, T L Jetton, P A Labosky, M Ray, R W Stein, M A Magnuson, B L Hogan, C V Wright. Development 1996
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Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells.
Leonardo Velazco-Cruz, Jiwon Song, Kristina G Maxwell, Madeleine M Goedegebuure, Punn Augsornworawat, Nathaniel J Hogrebe, Jeffrey R Millman. Stem Cell Reports 2019
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Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells.
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Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis.
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Very slow turnover of beta-cells in aged adult mice.
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Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis.
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A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.