Shanta M Messerli, Shilpa Prabhakar, Yi Tang, Khalid Shah, Maria L Cortes, Vidya Murthy, Ralph Weissleder, Xandra O Breakefield, Ching-Hsuan Tung. Neoplasia 2004
Times Cited: 75
Times Cited: 75
Times Cited
Times Co-cited
Similarity
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes.
R Weissleder, C H Tung, U Mahmood, A Bogdanov. Nat Biotechnol 1999
R Weissleder, C H Tung, U Mahmood, A Bogdanov. Nat Biotechnol 1999
44
In vivo molecular target assessment of matrix metalloproteinase inhibition.
C Bremer, C H Tung, R Weissleder. Nat Med 2001
C Bremer, C H Tung, R Weissleder. Nat Med 2001
40
In vivo imaging of proteolytic enzyme activity using a novel molecular reporter.
C H Tung, U Mahmood, S Bredow, R Weissleder. Cancer Res 2000
C H Tung, U Mahmood, S Bredow, R Weissleder. Cancer Res 2000
34
Tumor imaging by means of proteolytic activation of cell-penetrating peptides.
Tao Jiang, Emilia S Olson, Quyen T Nguyen, Melinda Roy, Patricia A Jennings, Roger Y Tsien. Proc Natl Acad Sci U S A 2004
Tao Jiang, Emilia S Olson, Quyen T Nguyen, Melinda Roy, Patricia A Jennings, Roger Y Tsien. Proc Natl Acad Sci U S A 2004
24
Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging.
C H Tung, S Bredow, U Mahmood, R Weissleder. Bioconjug Chem 1999
C H Tung, S Bredow, U Mahmood, R Weissleder. Bioconjug Chem 1999
22
Near-infrared fluorescent imaging of tumor apoptosis.
Alexander Petrovsky, Eyk Schellenberger, Lee Josephson, Ralph Weissleder, Alexei Bogdanov. Cancer Res 2003
Alexander Petrovsky, Eyk Schellenberger, Lee Josephson, Ralph Weissleder, Alexei Bogdanov. Cancer Res 2003
22
Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter.
Benedict Law, Alejandro Curino, Thomas H Bugge, Ralph Weissleder, Ching-Hsuan Tung. Chem Biol 2004
Benedict Law, Alejandro Curino, Thomas H Bugge, Ralph Weissleder, Ching-Hsuan Tung. Chem Biol 2004
22
Developing a peptide-based near-infrared molecular probe for protease sensing.
Wellington Pham, Yongdoo Choi, Ralph Weissleder, Ching-Hsuan Tung. Bioconjug Chem 2004
Wellington Pham, Yongdoo Choi, Ralph Weissleder, Ching-Hsuan Tung. Bioconjug Chem 2004
20
Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor.
Farouc A Jaffer, Dong-Eog Kim, Luisa Quinti, Ching-Hsuan Tung, Elena Aikawa, Ashvin N Pande, Rainer H Kohler, Guo-Ping Shi, Peter Libby, Ralph Weissleder. Circulation 2007
Farouc A Jaffer, Dong-Eog Kim, Luisa Quinti, Ching-Hsuan Tung, Elena Aikawa, Ashvin N Pande, Rainer H Kohler, Guo-Ping Shi, Peter Libby, Ralph Weissleder. Circulation 2007
20
In vivo imaging of proteolytic activity in atherosclerosis.
Jiqiu Chen, Ching-Hsuan Tung, Umar Mahmood, Vasilis Ntziachristos, Robert Gyurko, Mark C Fishman, Paul L Huang, Ralph Weissleder. Circulation 2002
Jiqiu Chen, Ching-Hsuan Tung, Umar Mahmood, Vasilis Ntziachristos, Robert Gyurko, Mark C Fishman, Paul L Huang, Ralph Weissleder. Circulation 2002
18
Noninvasive real-time imaging of apoptosis.
Bharathi Laxman, Daniel E Hall, Mahaveer Swaroop Bhojani, Daniel A Hamstra, Thomas L Chenevert, Brian D Ross, Alnawaz Rehemtulla. Proc Natl Acad Sci U S A 2002
Bharathi Laxman, Daniel E Hall, Mahaveer Swaroop Bhojani, Daniel A Hamstra, Thomas L Chenevert, Brian D Ross, Alnawaz Rehemtulla. Proc Natl Acad Sci U S A 2002
18
In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas.
Khalid Shah, Ching-Hsuan Tung, Chung-Hsun Chang, Eric Slootweg, Terence O'Loughlin, Xandra O Breakefield, Ralph Weissleder. Cancer Res 2004
Khalid Shah, Ching-Hsuan Tung, Chung-Hsun Chang, Eric Slootweg, Terence O'Loughlin, Xandra O Breakefield, Ralph Weissleder. Cancer Res 2004
35
Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes.
Christoph Bremer, Ching-Hsuan Tung, Alex Bogdanov, Ralph Weissleder. Radiology 2002
Christoph Bremer, Ching-Hsuan Tung, Alex Bogdanov, Ralph Weissleder. Radiology 2002
16
Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy.
Eyk A Schellenberger, Alexei Bogdanov, Alexander Petrovsky, Vasilis Ntziachristos, Ralph Weissleder, Lee Josephson. Neoplasia 2003
Eyk A Schellenberger, Alexei Bogdanov, Alexander Petrovsky, Vasilis Ntziachristos, Ralph Weissleder, Lee Josephson. Neoplasia 2003
16
Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging.
Kwangmeyung Kim, Misu Lee, Hyungkyu Park, Jong-Ho Kim, Sungwon Kim, Hesson Chung, Kuiwon Choi, In-San Kim, Baik L Seong, Ick Chan Kwon. J Am Chem Soc 2006
Kwangmeyung Kim, Misu Lee, Hyungkyu Park, Jong-Ho Kim, Sungwon Kim, Hesson Chung, Kuiwon Choi, In-San Kim, Baik L Seong, Ick Chan Kwon. J Am Chem Soc 2006
16
Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice.
Katharina Marten, Christoph Bremer, Khashayarsha Khazaie, Mansoureh Sameni, Bonnie Sloane, Ching-Hsuan Tung, Ralph Weissleder. Gastroenterology 2002
Katharina Marten, Christoph Bremer, Khashayarsha Khazaie, Mansoureh Sameni, Bonnie Sloane, Ching-Hsuan Tung, Ralph Weissleder. Gastroenterology 2002
14
In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response.
Andreas Wunder, Ching-Hsuan Tung, Ulf Müller-Ladner, Ralph Weissleder, Umar Mahmood. Arthritis Rheum 2004
Andreas Wunder, Ching-Hsuan Tung, Ulf Müller-Ladner, Ralph Weissleder, Umar Mahmood. Arthritis Rheum 2004
14
Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.
C Bremer, S Bredow, U Mahmood, R Weissleder, C H Tung. Radiology 2001
C Bremer, S Bredow, U Mahmood, R Weissleder, C H Tung. Radiology 2001
14
In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe.
Farouc A Jaffer, Ching-Hsuan Tung, Robert E Gerszten, Ralph Weissleder. Arterioscler Thromb Vasc Biol 2002
Farouc A Jaffer, Ching-Hsuan Tung, Robert E Gerszten, Ralph Weissleder. Arterioscler Thromb Vasc Biol 2002
13
Near-infrared optical imaging of epidermal growth factor receptor in breast cancer xenografts.
Shi Ke, Xiaoxia Wen, Michael Gurfinkel, Chusilp Charnsangavej, Sidney Wallace, Eva M Sevick-Muraca, Chun Li. Cancer Res 2003
Shi Ke, Xiaoxia Wen, Michael Gurfinkel, Chusilp Charnsangavej, Sidney Wallace, Eva M Sevick-Muraca, Chun Li. Cancer Res 2003
13
Near-infrared optical imaging of protease activity for tumor detection.
U Mahmood, C H Tung, A Bogdanov, R Weissleder. Radiology 1999
U Mahmood, C H Tung, A Bogdanov, R Weissleder. Radiology 1999
13
Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis.
Kristin Bullok, David Piwnica-Worms. J Med Chem 2005
Kristin Bullok, David Piwnica-Worms. J Med Chem 2005
13
Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate.
Vasilis Ntziachristos, Eyk A Schellenberger, Jorge Ripoll, Doreen Yessayan, Edward Graves, Alexei Bogdanov, Lee Josephson, Ralph Weissleder. Proc Natl Acad Sci U S A 2004
Vasilis Ntziachristos, Eyk A Schellenberger, Jorge Ripoll, Doreen Yessayan, Edward Graves, Alexei Bogdanov, Lee Josephson, Ralph Weissleder. Proc Natl Acad Sci U S A 2004
12
Non-invasive detection of apoptosis using magnetic resonance imaging and a targeted contrast agent.
M Zhao, D A Beauregard, L Loizou, B Davletov, K M Brindle. Nat Med 2001
M Zhao, D A Beauregard, L Loizou, B Davletov, K M Brindle. Nat Med 2001
12
In vivo detection and imaging of phosphatidylserine expression during programmed cell death.
F G Blankenberg, P D Katsikis, J F Tait, R E Davis, L Naumovski, K Ohtsuki, S Kopiwoda, M J Abrams, M Darkes, R C Robbins,[...]. Proc Natl Acad Sci U S A 1998
F G Blankenberg, P D Katsikis, J F Tait, R E Davis, L Naumovski, K Ohtsuki, S Kopiwoda, M J Abrams, M Darkes, R C Robbins,[...]. Proc Natl Acad Sci U S A 1998
12
Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo.
Jun-o Deguchi, Masanori Aikawa, Ching-Hsuan Tung, Elena Aikawa, Dong-Eog Kim, Vasilis Ntziachristos, Ralph Weissleder, Peter Libby. Circulation 2006
Jun-o Deguchi, Masanori Aikawa, Ching-Hsuan Tung, Elena Aikawa, Dong-Eog Kim, Vasilis Ntziachristos, Ralph Weissleder, Peter Libby. Circulation 2006
12
Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction.
Jiqiu Chen, Ching-Hsuan Tung, Jennifer R Allport, Si Chen, Ralph Weissleder, Paul L Huang. Circulation 2005
Jiqiu Chen, Ching-Hsuan Tung, Jennifer R Allport, Si Chen, Ralph Weissleder, Paul L Huang. Circulation 2005
12
Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment.
Alexei A Bogdanov, Charles P Lin, Maria Simonova, Lars Matuszewski, Ralph Weissleder. Neoplasia 2002
Alexei A Bogdanov, Charles P Lin, Maria Simonova, Lars Matuszewski, Ralph Weissleder. Neoplasia 2002
19
Receptor-targeted optical imaging of tumors with near-infrared fluorescent ligands.
A Becker, C Hessenius, K Licha, B Ebert, U Sukowski, W Semmler, B Wiedenmann, C Grötzinger. Nat Biotechnol 2001
A Becker, C Hessenius, K Licha, B Ebert, U Sukowski, W Semmler, B Wiedenmann, C Grötzinger. Nat Biotechnol 2001
10
10
Protease sensors for bioimaging.
Martin Funovics, Ralph Weissleder, Ching-Hsuan Tung. Anal Bioanal Chem 2003
Martin Funovics, Ralph Weissleder, Ching-Hsuan Tung. Anal Bioanal Chem 2003
10
Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis.
Kristin E Bullok, Dustin Maxwell, Aparna H Kesarwala, Seth Gammon, Julie L Prior, Margaret Snow, Sam Stanley, David Piwnica-Worms. Biochemistry 2007
Kristin E Bullok, Dustin Maxwell, Aparna H Kesarwala, Seth Gammon, Julie L Prior, Margaret Snow, Sam Stanley, David Piwnica-Worms. Biochemistry 2007
10
In vivo imaging of beta-galactosidase activity using far red fluorescent switch.
Ching-Hsuan Tung, Qing Zeng, Khalid Shah, Dong-Eog Kim, Dawid Schellingerhout, Ralph Weissleder. Cancer Res 2004
Ching-Hsuan Tung, Qing Zeng, Khalid Shah, Dong-Eog Kim, Dawid Schellingerhout, Ralph Weissleder. Cancer Res 2004
9
9
Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo.
Khalid Shah, Yi Tang, Xandra Breakefield, Ralph Weissleder. Oncogene 2003
Khalid Shah, Yi Tang, Xandra Breakefield, Ralph Weissleder. Oncogene 2003
9
Quantum dots for live cells, in vivo imaging, and diagnostics.
X Michalet, F F Pinaud, L A Bentolila, J M Tsay, S Doose, J J Li, G Sundaresan, A M Wu, S S Gambhir, S Weiss. Science 2005
X Michalet, F F Pinaud, L A Bentolila, J M Tsay, S Doose, J J Li, G Sundaresan, A M Wu, S S Gambhir, S Weiss. Science 2005
9
Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle.
David E Sosnovik, Eyk A Schellenberger, Matthias Nahrendorf, Mikhail S Novikov, Takashi Matsui, George Dai, Fred Reynolds, Luanda Grazette, Anthony Rosenzweig, Ralph Weissleder,[...]. Magn Reson Med 2005
David E Sosnovik, Eyk A Schellenberger, Matthias Nahrendorf, Mikhail S Novikov, Takashi Matsui, George Dai, Fred Reynolds, Luanda Grazette, Anthony Rosenzweig, Ralph Weissleder,[...]. Magn Reson Med 2005
9
A fluorescent nanosensor for apoptotic cells.
Luisa Quinti, Ralph Weissleder, Ching-Hsuan Tung. Nano Lett 2006
Luisa Quinti, Ralph Weissleder, Ching-Hsuan Tung. Nano Lett 2006
10
Selective antitumor effect of novel protease-mediated photodynamic agent.
Yongdoo Choi, Ralph Weissleder, Ching-Hsuan Tung. Cancer Res 2006
Yongdoo Choi, Ralph Weissleder, Ching-Hsuan Tung. Cancer Res 2006
9
Near-infrared optical imaging of proteases in cancer.
Umar Mahmood, Ralph Weissleder. Mol Cancer Ther 2003
Umar Mahmood, Ralph Weissleder. Mol Cancer Ther 2003
9
In-vivo imaging of tumor associated urokinase-type plasminogen activator activity.
Jong-Kai Hsiao, Benedict Law, Ralph Weissleder, Ching-Hsuan Tung. J Biomed Opt 2006
Jong-Kai Hsiao, Benedict Law, Ralph Weissleder, Ching-Hsuan Tung. J Biomed Opt 2006
26
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival.
Quyen T Nguyen, Emilia S Olson, Todd A Aguilera, Tao Jiang, Miriam Scadeng, Lesley G Ellies, Roger Y Tsien. Proc Natl Acad Sci U S A 2010
Quyen T Nguyen, Emilia S Olson, Todd A Aguilera, Tao Jiang, Miriam Scadeng, Lesley G Ellies, Roger Y Tsien. Proc Natl Acad Sci U S A 2010
9
Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy.
Khalid Shah, Ching-Hsuan Tung, Katherine Yang, Ralph Weissleder, Xandra O Breakefield. Cancer Res 2004
Khalid Shah, Ching-Hsuan Tung, Katherine Yang, Ralph Weissleder, Xandra O Breakefield. Cancer Res 2004
8
A novel near-infrared fluorescence sensor for detection of thrombin activation in blood.
Ching-Hsuan Tung, Robert E Gerszten, Farouc A Jaffer, Ralph Weissleder. Chembiochem 2002
Ching-Hsuan Tung, Robert E Gerszten, Farouc A Jaffer, Ralph Weissleder. Chembiochem 2002
10
Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate.
Woo Kyung Moon, Yuhui Lin, Terence O'Loughlin, Yi Tang, Dong-Eog Kim, Ralph Weissleder, Ching-Hsuan Tung. Bioconjug Chem 2003
Woo Kyung Moon, Yuhui Lin, Terence O'Loughlin, Yi Tang, Dong-Eog Kim, Ralph Weissleder, Ching-Hsuan Tung. Bioconjug Chem 2003
8
A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging.
Ching-Hsuan Tung, Yuhui Lin, Woo Kyung Moon, Ralph Weissleder. Chembiochem 2002
Ching-Hsuan Tung, Yuhui Lin, Woo Kyung Moon, Ralph Weissleder. Chembiochem 2002
8
Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi.
Farouc A Jaffer, Ching-Hsuan Tung, Joanna J Wykrzykowska, Nan-Hui Ho, Aiilyan K Houng, Guy L Reed, Ralph Weissleder. Circulation 2004
Farouc A Jaffer, Ching-Hsuan Tung, Joanna J Wykrzykowska, Nan-Hui Ho, Aiilyan K Houng, Guy L Reed, Ralph Weissleder. Circulation 2004
8
Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping.
Sungjee Kim, Yong Taik Lim, Edward G Soltesz, Alec M De Grand, Jaihyoung Lee, Akira Nakayama, J Anthony Parker, Tomislav Mihaljevic, Rita G Laurence, Delphine M Dor,[...]. Nat Biotechnol 2004
Sungjee Kim, Yong Taik Lim, Edward G Soltesz, Alec M De Grand, Jaihyoung Lee, Akira Nakayama, J Anthony Parker, Tomislav Mihaljevic, Rita G Laurence, Delphine M Dor,[...]. Nat Biotechnol 2004
8
Magneto/optical annexin V, a multimodal protein.
Eyk A Schellenberger, David Sosnovik, Ralph Weissleder, Lee Josephson. Bioconjug Chem 2004
Eyk A Schellenberger, David Sosnovik, Ralph Weissleder, Lee Josephson. Bioconjug Chem 2004
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.