A citation-based method for searching scientific literature

Markus Welcker, Amir Orian, Jianping Jin, Jonathan E Grim, J Wade Harper, Robert N Eisenman, Bruce E Clurman. Proc Natl Acad Sci U S A 2004
Times Cited: 651







List of co-cited articles
1101 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
Masayoshi Yada, Shigetsugu Hatakeyama, Takumi Kamura, Masaaki Nishiyama, Ryosuke Tsunematsu, Hiroyuki Imaki, Noriko Ishida, Fumihiko Okumura, Keiko Nakayama, Keiichi I Nakayama. EMBO J 2004
575
39

MYC on the path to cancer.
Chi V Dang. Cell 2012
26


Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.
R Sears, F Nuckolls, E Haura, Y Taya, K Tamai, J R Nevins. Genes Dev 2000
918
19

MYC degradation.
Amy S Farrell, Rosalie C Sears. Cold Spring Harb Perspect Med 2014
230
19

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells.
Zuqin Nie, Gangqing Hu, Gang Wei, Kairong Cui, Arito Yamane, Wolfgang Resch, Ruoning Wang, Douglas R Green, Lino Tessarollo, Rafael Casellas,[...]. Cell 2012
704
15

Reflecting on 25 years with MYC.
Natalie Meyer, Linda Z Penn. Nat Rev Cancer 2008
15

Skp2 regulates Myc protein stability and activity.
So Young Kim, Andreas Herbst, Kathryn A Tworkowski, Simone E Salghetti, William P Tansey. Mol Cell 2003
403
15

The ubiquitin-specific protease USP28 is required for MYC stability.
Nikita Popov, Michael Wanzel, Mandy Madiredjo, Dong Zhang, Roderick Beijersbergen, Rene Bernards, Roland Moll, Stephen J Elledge, Martin Eilers. Nat Cell Biol 2007
310
15

FBXW7: a critical tumor suppressor of human cancers.
Chien-Hung Yeh, Marcia Bellon, Christophe Nicot. Mol Cancer 2018
199
15

The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
Abdolrahman S Nateri, Lluís Riera-Sans, Clive Da Costa, Axel Behrens. Science 2004
300
14

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
D M Koepp, L K Schaefer, X Ye, K Keyomarsi, C Chu, J W Harper, S J Elledge. Science 2001
628
14

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells.
Elizabeth Yeh, Melissa Cunningham, Hugh Arnold, Dawn Chasse, Teresa Monteith, Giovanni Ivaldi, William C Hahn, P Todd Stukenberg, Shirish Shenolikar, Takafumi Uchida,[...]. Nat Cell Biol 2004
603
14

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription.
Natalie von der Lehr, Sara Johansson, Siqin Wu, Fuad Bahram, Alina Castell, Cihan Cetinkaya, Per Hydbring, Ingrid Weidung, Keiko Nakayama, Keiichi I Nakayama,[...]. Mol Cell 2003
385
13

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.
H Strohmaier, C H Spruck, P Kaiser, K A Won, O Sangfelt, S I Reed. Nature 2001
489
13

BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Jake E Delmore, Ghayas C Issa, Madeleine E Lemieux, Peter B Rahl, Junwei Shi, Hannah M Jacobs, Efstathios Kastritis, Timothy Gilpatrick, Ronald M Paranal, Jun Qi,[...]. Cell 2011
13

The nucleolar ubiquitin-specific protease USP36 deubiquitinates and stabilizes c-Myc.
Xiao-Xin Sun, Xia He, Li Yin, Masayuki Komada, Rosalie C Sears, Mu-Shui Dai. Proc Natl Acad Sci U S A 2015
109
13

FBXW7/hCDC4 is a general tumor suppressor in human cancer.
Shahab Akhoondi, Dahui Sun, Natalie von der Lehr, Sophia Apostolidou, Kathleen Klotz, Alena Maljukova, Diana Cepeda, Heidi Fiegl, Dimitra Dafou, Christian Marth,[...]. Cancer Res 2007
369
12


Targeting oncogenic Myc as a strategy for cancer treatment.
Hui Chen, Hudan Liu, Guoliang Qing. Signal Transduct Target Ther 2018
313
12

Target gene-independent functions of MYC oncoproteins.
Apoorva Baluapuri, Elmar Wolf, Martin Eilers. Nat Rev Mol Cell Biol 2020
76
15

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.
Markus Welcker, Amir Orian, Jonathan E Grim, Robert N Eisenman, Bruce E Clurman. Curr Biol 2004
235
11

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.
Ryan J Davis, Markus Welcker, Bruce E Clurman. Cancer Cell 2014
235
11

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma.
Tobias Otto, Sebastian Horn, Markus Brockmann, Ursula Eilers, Lars Schüttrumpf, Nikita Popov, Anna Marie Kenney, Johannes H Schulte, Roderick Beijersbergen, Holger Christiansen,[...]. Cancer Cell 2009
365
11

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.
Sovana Adhikary, Federica Marinoni, Andreas Hock, Esther Hulleman, Nikita Popov, Rudi Beier, Sandra Bernard, Micaela Quarto, Maria Capra, Stephan Goettig,[...]. Cell 2005
287
10

Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors.
Mark W Richards, Selena G Burgess, Evon Poon, Anne Carstensen, Martin Eilers, Louis Chesler, Richard Bayliss. Proc Natl Acad Sci U S A 2016
85
11

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama, Daming Gao, Alan Tseng, Richard S Maser, Bo Zhai, Lixin Wan, Alejandro Gutierrez, Alan W Lau,[...]. Nature 2011
474
10

Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Daibiao Xiao, Ming Yue, Hexiu Su, Ping Ren, Jue Jiang, Feng Li, Yufeng Hu, Haining Du, Hudan Liu, Guoliang Qing. Mol Cell 2016
82
12

FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Jian-Hua Mao, Il-Jin Kim, Di Wu, Joan Climent, Hio Chung Kang, Reyno DelRosario, Allan Balmain. Science 2008
311
10

Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
Bing Hao, Stephanie Oehlmann, Mathew E Sowa, J Wade Harper, Nikola P Pavletich. Mol Cell 2007
331
10

Transcriptional amplification in tumor cells with elevated c-Myc.
Charles Y Lin, Jakob Lovén, Peter B Rahl, Ronald M Paranal, Christopher B Burge, James E Bradner, Tong Ihn Lee, Richard A Young. Cell 2012
956
10

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
10

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.
Wenyi Wei, Jianping Jin, Susanne Schlisio, J Wade Harper, William G Kaelin. Cancer Cell 2005
321
9

Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants.
Michael T Hemann, Anka Bric, Julie Teruya-Feldstein, Andreas Herbst, Jonas A Nilsson, Carlos Cordon-Cardo, John L Cleveland, William P Tansey, Scott W Lowe. Nature 2005
343
9

Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy.
Huiying Han, Atul D Jain, Mihai I Truica, Javier Izquierdo-Ferrer, Jonathan F Anker, Barbara Lysy, Vinay Sagar, Yi Luan, Zachary R Chalmers, Kenji Unno,[...]. Cancer Cell 2019
115
9

Recent insight into the role of FBXW7 as a tumor suppressor.
Kanae Yumimoto, Keiichi I Nakayama. Semin Cancer Biol 2020
41
21

Ras enhances Myc protein stability.
R Sears, G Leone, J DeGregori, J R Nevins. Mol Cell 1999
355
8

USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer.
J Pan, Q Deng, C Jiang, X Wang, T Niu, H Li, T Chen, J Jin, W Pan, X Cai,[...]. Oncogene 2015
83
9

Fbw7 dimerization determines the specificity and robustness of substrate degradation.
Markus Welcker, Elizabeth A Larimore, Jherek Swanger, Maria T Bengoechea-Alonso, Jonathan E Grim, Johan Ericsson, Ning Zheng, Bruce E Clurman. Genes Dev 2013
66
12

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
Jonathan E Grim, Michael P Gustafson, Roli K Hirata, Amanda C Hagar, Jherek Swanger, Markus Welcker, Harry C Hwang, Johan Ericsson, David W Russell, Bruce E Clurman. J Cell Biol 2008
84
9

Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).
Anders Sundqvist, Maria T Bengoechea-Alonso, Xin Ye, Vasyl Lukiyanchuk, Jianping Jin, J Wade Harper, Johan Ericsson. Cell Metab 2005
307
8

Roles of F-box proteins in cancer.
Zhiwei Wang, Pengda Liu, Hiroyuki Inuzuka, Wenyi Wei. Nat Rev Cancer 2014
302
8

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
499
8

The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability.
Bryan King, Thomas Trimarchi, Linsey Reavie, Luyao Xu, Jasper Mullenders, Panagiotis Ntziachristos, Beatriz Aranda-Orgilles, Arianne Perez-Garcia, Junwei Shi, Christopher Vakoc,[...]. Cell 2013
222
8


MYC activation is a hallmark of cancer initiation and maintenance.
Meital Gabay, Yulin Li, Dean W Felsher. Cold Spring Harb Perspect Med 2014
425
8

MYC Deregulation in Primary Human Cancers.
Manpreet Kalkat, Jason De Melo, Katherine Ashley Hickman, Corey Lourenco, Cornelia Redel, Diana Resetca, Aaliya Tamachi, William B Tu, Linda Z Penn. Genes (Basel) 2017
171
8

MYC, metabolism, cell growth, and tumorigenesis.
Chi V Dang. Cold Spring Harb Perspect Med 2013
391
7

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
7

Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination.
Xiaoguang Fang, Wenchao Zhou, Qiulian Wu, Zhi Huang, Yu Shi, Kailin Yang, Cong Chen, Qi Xie, Stephen C Mack, Xiuxing Wang,[...]. J Exp Med 2017
74
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.