Dwight Cordero, Ralph Marcucio, Diane Hu, William Gaffield, Minal Tapadia, Jill A Helms. J Clin Invest 2004
Times Cited: 138
Times Cited: 138
Times Cited
Times Co-cited
Similarity
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
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Molecular interactions coordinating the development of the forebrain and face.
Ralph S Marcucio, Dwight R Cordero, Diane Hu, Jill A Helms. Dev Biol 2005
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Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia.
Juhee Jeong, Junhao Mao, Toyoaki Tenzen, Andreas H Kottmann, Andrew P McMahon. Genes Dev 2004
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D Hu, J A Helms. Development 1999
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A zone of frontonasal ectoderm regulates patterning and growth in the face.
Diane Hu, Ralph S Marcucio, Jill A Helms. Development 2003
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A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm.
Diane Hu, Ralph S Marcucio. Development 2009
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Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
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Early Hedgehog signaling from neural to oral epithelium organizes anterior craniofacial development.
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Cdo functions at multiple points in the Sonic Hedgehog pathway, and Cdo-deficient mice accurately model human holoprosencephaly.
Wei Zhang, Jong-Sun Kang, Francesca Cole, Min-Jeong Yi, Robert S Krauss. Dev Cell 2006
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Haploinsufficiency of Six3 fails to activate Sonic hedgehog expression in the ventral forebrain and causes holoprosencephaly.
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Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.
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Inhibition of sonic hedgehog signaling in vivo results in craniofacial neural crest cell death.
S C Ahlgren, M Bronner-Fraser. Curr Biol 1999
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Multiple hits during early embryonic development: digenic diseases and holoprosencephaly.
Jeffrey E Ming, Maximilian Muenke. Am J Hum Genet 2002
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Hedgehog signaling is required for cranial neural crest morphogenesis and chondrogenesis at the midline in the zebrafish skull.
Naoyuki Wada, Yashar Javidan, Sarah Nelson, Thomas J Carney, Robert N Kelsh, Thomas F Schilling. Development 2005
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Genetics of ventral forebrain development and holoprosencephaly.
M Muenke, P A Beachy. Curr Opin Genet Dev 2000
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Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened.
James K Chen, Jussi Taipale, Michael K Cooper, Philip A Beachy. Genes Dev 2002
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The molecular genetics of holoprosencephaly.
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
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Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape.
Nathan M Young, H Jonathan Chong, Diane Hu, Benedikt Hallgrímsson, Ralph S Marcucio. Development 2010
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A series of normal stages in the development of the chick embryo.
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The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development.
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Fetal ethanol exposure activates protein kinase A and impairs Shh expression in prechordal mesendoderm cells in the pathogenesis of holoprosencephaly.
Kazushi Aoto, Yayoi Shikata, Daisuke Higashiyama, Kohei Shiota, Jun Motoyama. Birth Defects Res A Clin Mol Teratol 2008
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Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly.
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Hedgehog signaling in animal development: paradigms and principles.
P W Ingham, A P McMahon. Genes Dev 2001
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The cell surface membrane proteins Cdo and Boc are components and targets of the Hedgehog signaling pathway and feedback network in mice.
Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
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Mouse Shh is required for prechordal plate maintenance during brain and craniofacial morphogenesis.
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Unique organization of the frontonasal ectodermal zone in birds and mammals.
Diane Hu, Ralph S Marcucio. Dev Biol 2009
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A primary cilia-dependent etiology for midline facial disorders.
Samantha A Brugmann, Nancy C Allen, Aaron W James, Zesemayat Mekonnen, Elena Madan, Jill A Helms. Hum Mol Genet 2010
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The mutational spectrum of the sonic hedgehog gene in holoprosencephaly: SHH mutations cause a significant proportion of autosomal dominant holoprosencephaly.
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Holoprosencephaly: clinical, anatomic, and molecular dimensions.
M Michael Cohen. Birth Defects Res A Clin Mol Teratol 2006
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Microform holoprosencephaly in mice that lack the Ig superfamily member Cdon.
Francesca Cole, Robert S Krauss. Curr Biol 2003
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Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
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Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Maisa Seppala, Michael J Depew, David C Martinelli, Chen-Ming Fan, Paul T Sharpe, Martyn T Cobourne. J Clin Invest 2007
Maisa Seppala, Michael J Depew, David C Martinelli, Chen-Ming Fan, Paul T Sharpe, Martyn T Cobourne. J Clin Invest 2007
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An early role for sonic hedgehog from foregut endoderm in jaw development: ensuring neural crest cell survival.
José M Brito, Marie-Aimée Teillet, Nicole M Le Douarin. Proc Natl Acad Sci U S A 2006
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MicroRNA Mirn140 modulates Pdgf signaling during palatogenesis.
Johann K Eberhart, Xinjun He, Mary E Swartz, Yi-Lin Yan, Hao Song, Taylor C Boling, Allison K Kunerth, Macie B Walker, Charles B Kimmel, John H Postlethwait. Nat Genet 2008
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Holoprosencephaly.
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Wnt signaling mediates regional specification in the vertebrate face.
Samantha A Brugmann, L Henry Goodnough, Alex Gregorieff, Philipp Leucht, Derk ten Berge, Christophe Fuerer, Hans Clevers, Roel Nusse, Jill A Helms. Development 2007
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Cdon mutation and fetal ethanol exposure synergize to produce midline signaling defects and holoprosencephaly spectrum disorders in mice.
Mingi Hong, Robert S Krauss. PLoS Genet 2012
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The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.
Henry W Kietzman, Joshua L Everson, Kathleen K Sulik, Robert J Lipinski. PLoS One 2014
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Sonic hedgehog rescues cranial neural crest from cell death induced by ethanol exposure.
Sara C Ahlgren, Vijaya Thakur, Marianne Bronner-Fraser. Proc Natl Acad Sci U S A 2002
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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
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THE FACE PREDICTS THE BRAIN: DIAGNOSTIC SIGNIFICANCE OF MEDIAN FACIAL ANOMALIES FOR HOLOPROSENCEPHALY (ARHINENCEPHALY).
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Signaling by bone morphogenetic proteins directs formation of an ectodermal signaling center that regulates craniofacial development.
Silvia Foppiano, Diane Hu, Ralph S Marcucio. Dev Biol 2007
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Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
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Cilia and Hedgehog responsiveness in the mouse.
Danwei Huangfu, Kathryn V Anderson. Proc Natl Acad Sci U S A 2005
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Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein.
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10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.