A citation-based method for searching scientific literature

Keisuke Ito, Atsushi Hirao, Fumio Arai, Sahoko Matsuoka, Keiyo Takubo, Isao Hamaguchi, Kana Nomiyama, Kentaro Hosokawa, Kazuhiro Sakurada, Naomi Nakagata, Yasuo Ikeda, Tak W Mak, Toshio Suda. Nature 2004
Times Cited: 890







List of co-cited articles
1346 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.
Zuzana Tothova, Ramya Kollipara, Brian J Huntly, Benjamin H Lee, Diego H Castrillon, Dana E Cullen, Elizabeth P McDowell, Suzan Lazo-Kallanian, Ifor R Williams, Christopher Sears,[...]. Cell 2007
34

Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.
Keisuke Ito, Atsushi Hirao, Fumio Arai, Keiyo Takubo, Sahoko Matsuoka, Kana Miyamoto, Masako Ohmura, Kazuhito Naka, Kentaro Hosokawa, Yasuo Ikeda,[...]. Nat Med 2006
989
34


The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.
Tugba Simsek, Fatih Kocabas, Junke Zheng, Ralph J Deberardinis, Ahmed I Mahmoud, Eric N Olson, Jay W Schneider, Cheng Cheng Zhang, Hesham A Sadek. Cell Stem Cell 2010
717
25

Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.
Keiyo Takubo, Go Nagamatsu, Chiharu I Kobayashi, Ayako Nakamura-Ishizu, Hiroshi Kobayashi, Eiji Ikeda, Nobuhito Goda, Yasmeen Rahimi, Randall S Johnson, Tomoyoshi Soga,[...]. Cell Stem Cell 2013
492
25

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.
Keiyo Takubo, Nobuhito Goda, Wakako Yamada, Hirono Iriuchishima, Eiji Ikeda, Yoshiaki Kubota, Haruko Shima, Randall S Johnson, Atsushi Hirao, Makoto Suematsu,[...]. Cell Stem Cell 2010
621
23

TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species.
Chong Chen, Yu Liu, Runhua Liu, Tsuneo Ikenoue, Kun-Liang Guan, Yang Liu, Pan Zheng. J Exp Med 2008
518
22

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.
Marisa M Juntilla, Vineet D Patil, Marco Calamito, Rohan P Joshi, Morris J Birnbaum, Gary A Koretzky. Blood 2010
210
20

Foxo3a is essential for maintenance of the hematopoietic stem cell pool.
Kana Miyamoto, Kiyomi Y Araki, Kazuhito Naka, Fumio Arai, Keiyo Takubo, Satoshi Yamazaki, Sahoko Matsuoka, Takeshi Miyamoto, Keisuke Ito, Masako Ohmura,[...]. Cell Stem Cell 2007
645
20

Autophagy maintains the metabolism and function of young and old stem cells.
Theodore T Ho, Matthew R Warr, Emmalee R Adelman, Olivia M Lansinger, Johanna Flach, Evgenia V Verovskaya, Maria E Figueroa, Emmanuelle Passegué. Nature 2017
461
18

Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation.
Wen-Mei Yu, Xia Liu, Jinhua Shen, Olga Jovanovic, Elena E Pohl, Stanton L Gerson, Toren Finkel, Hal E Broxmeyer, Cheng-Kui Qu. Cell Stem Cell 2013
209
17

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
15

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis.
Mary Mohrin, Emer Bourke, David Alexander, Matthew R Warr, Keegan Barry-Holson, Michelle M Le Beau, Ciaran G Morrison, Emmanuelle Passegué. Cell Stem Cell 2010
421
15

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity.
Nicola Vannini, Mukul Girotra, Olaia Naveiras, Gennady Nikitin, Vasco Campos, Sonja Giger, Aline Roch, Johan Auwerx, Matthias P Lutolf. Nat Commun 2016
147
15

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair.
Anne Wilson, Elisa Laurenti, Gabriela Oser, Richard C van der Wath, William Blanco-Bose, Maike Jaworski, Sandra Offner, Cyrille F Dunant, Leonid Eshkind, Ernesto Bockamp,[...]. Cell 2008
14

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.
Derrick J Rossi, David Bryder, Jun Seita, Andre Nussenzweig, Jan Hoeijmakers, Irving L Weissman. Nature 2007
778
13

Metabolic requirements for the maintenance of self-renewing stem cells.
Keisuke Ito, Toshio Suda. Nat Rev Mol Cell Biol 2014
632
13

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.
Dagmar Walter, Amelie Lier, Anja Geiselhart, Frederic B Thalheimer, Sina Huntscha, Mirko C Sobotta, Bettina Moehrle, David Brocks, Irem Bayindir, Paul Kaschutnig,[...]. Nature 2015
381
13

Metabolic regulation of hematopoietic stem cells in the hypoxic niche.
Toshio Suda, Keiyo Takubo, Gregg L Semenza. Cell Stem Cell 2011
527
13

The bone marrow niche for haematopoietic stem cells.
Sean J Morrison, David T Scadden. Nature 2014
12

Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment.
Aya Ludin, Shiri Gur-Cohen, Karin Golan, Kerstin B Kaufmann, Tomer Itkin, Chiara Medaglia, Xin-Jiang Lu, Guy Ledergor, Orit Kollet, Tsvee Lapidot. Antioxid Redox Signal 2014
183
12

ATM activation by oxidative stress.
Zhi Guo, Sergei Kozlov, Martin F Lavin, Maria D Person, Tanya T Paull. Science 2010
761
12

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells.
Takashi Yahata, Tomomi Takanashi, Yukari Muguruma, Abd Aziz Ibrahim, Hideyuki Matsuzawa, Tomoko Uno, Yin Sheng, Makoto Onizuka, Mamoru Ito, Shunichi Kato,[...]. Blood 2011
208
12

Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.
Gudmundur L Norddahl, Cornelis J Pronk, Martin Wahlestedt, Gerd Sten, Jens M Nygren, Amol Ugale, Mikael Sigvardsson, David Bryder. Cell Stem Cell 2011
177
12

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.
Kyoko Ito, Raphaël Turcotte, Jinhua Cui, Samuel E Zimmerman, Sandra Pinho, Toshihide Mizoguchi, Fumio Arai, Judith M Runnels, Clemens Alt, Julie Teruya-Feldstein,[...]. Science 2016
187
12

A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance.
Keisuke Ito, Arkaitz Carracedo, Dror Weiss, Fumio Arai, Ugo Ala, David E Avigan, Zachary T Schafer, Ronald M Evans, Toshio Suda, Chih-Hao Lee,[...]. Nat Med 2012
474
12

The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells.
Maria Maryanovich, Galia Oberkovitz, Hagit Niv, Lidiya Vorobiyov, Yehudit Zaltsman, Ori Brenner, Tsvee Lapidot, Steffen Jung, Atan Gross. Nat Cell Biol 2012
107
12

The mitochondrial respiratory chain is essential for haematopoietic stem cell function.
Elena Ansó, Samuel E Weinberg, Lauren P Diebold, Benjamin J Thompson, Sébastien Malinge, Paul T Schumacker, Xin Liu, Yuannyu Zhang, Zhen Shao, Mya Steadman,[...]. Nat Cell Biol 2017
166
12

Direct measurement of local oxygen concentration in the bone marrow of live animals.
Joel A Spencer, Francesca Ferraro, Emmanuel Roussakis, Alyssa Klein, Juwell Wu, Judith M Runnels, Walid Zaher, Luke J Mortensen, Clemens Alt, Raphaël Turcotte,[...]. Nature 2014
668
11

Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency.
Raymond Liang, Tasleem Arif, Svetlana Kalmykova, Artem Kasianov, Miao Lin, Vijay Menon, Jiajing Qiu, Jeffrey M Bernitz, Kateri Moore, Fangming Lin,[...]. Cell Stem Cell 2020
86
12

Adult haematopoietic stem cell niches.
Genevieve M Crane, Elise Jeffery, Sean J Morrison. Nat Rev Immunol 2017
383
10

mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Chong Chen, Yu Liu, Yang Liu, Pan Zheng. Sci Signal 2009
441
10

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance.
Monika Mortensen, Elizabeth J Soilleux, Gordana Djordjevic, Rebecca Tripp, Michael Lutteropp, Elham Sadighi-Akha, Amanda J Stranks, Julie Glanville, Samantha Knight, Sten-Eirik W Jacobsen,[...]. J Exp Med 2011
423
10

FOXO3A directs a protective autophagy program in haematopoietic stem cells.
Matthew R Warr, Mikhail Binnewies, Johanna Flach, Damien Reynaud, Trit Garg, Ritu Malhotra, Jayanta Debnath, Emmanuelle Passegué. Nature 2013
402
10


PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention.
Jiwang Zhang, Justin C Grindley, Tong Yin, Sachintha Jayasinghe, Xi C He, Jason T Ross, Jeffrey S Haug, Dawn Rupp, Kimberly S Porter-Westpfahl, Leanne M Wiedemann,[...]. Nature 2006
631
10

Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging.
Mary Mohrin, Jiyung Shin, Yufei Liu, Katharine Brown, Hanzhi Luo, Yannan Xi, Cole M Haynes, Danica Chen. Science 2015
302
10

Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.
Ying-Hua Wang, William J Israelsen, Dongjun Lee, Vionnie W C Yu, Nathaniel T Jeanson, Clary B Clish, Lewis C Cantley, Matthew G Vander Heiden, David T Scadden. Cell 2014
227
10

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells.
Omer H Yilmaz, Riccardo Valdez, Brian K Theisen, Wei Guo, David O Ferguson, Hong Wu, Sean J Morrison. Nature 2006
10

Haematopoietic stem cell activity and interactions with the niche.
Sandra Pinho, Paul S Frenette. Nat Rev Mol Cell Biol 2019
369
10

Dye-Independent Methods Reveal Elevated Mitochondrial Mass in Hematopoietic Stem Cells.
Mariana Justino de Almeida, Larry L Luchsinger, David J Corrigan, Linda J Williams, Hans-Willem Snoeck. Cell Stem Cell 2017
115
10


Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function.
Els Mansell, Valgardur Sigurdsson, Elitza Deltcheva, John Brown, Chela James, Kenichi Miharada, Shamit Soneji, Jonas Larsson, Tariq Enver. Cell Stem Cell 2021
39
25

SIRT3 reverses aging-associated degeneration.
Katharine Brown, Stephanie Xie, Xiaolei Qiu, Mary Mohrin, Jiyung Shin, Yufei Liu, Dan Zhang, David T Scadden, Danica Chen. Cell Rep 2013
268
9

Bmi1 regulates mitochondrial function and the DNA damage response pathway.
Jie Liu, Liu Cao, Jichun Chen, Shiwei Song, In Hye Lee, Celia Quijano, Hongjun Liu, Keyvan Keyvanfar, Haoqian Chen, Long-Yue Cao,[...]. Nature 2009
359
9


Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.
Johanna Flach, Sietske T Bakker, Mary Mohrin, Pauline C Conroy, Eric M Pietras, Damien Reynaud, Silvia Alvarez, Morgan E Diolaiti, Fernando Ugarte, E Camilla Forsberg,[...]. Nature 2014
382
9

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection.
Megan T Baldridge, Katherine Y King, Nathan C Boles, David C Weksberg, Margaret A Goodell. Nature 2010
574
9

p38α Activates Purine Metabolism to Initiate Hematopoietic Stem/Progenitor Cell Cycling in Response to Stress.
Daiki Karigane, Hiroshi Kobayashi, Takayuki Morikawa, Yukako Ootomo, Mashito Sakai, Go Nagamatsu, Yoshiaki Kubota, Nobuhito Goda, Michihiro Matsumoto, Emi K Nishimura,[...]. Cell Stem Cell 2016
63
14

Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock.
Charlie R Mantel, Heather A O'Leary, Brahmananda R Chitteti, XinXin Huang, Scott Cooper, Giao Hangoc, Nickolay Brustovetsky, Edward F Srour, Man Ryul Lee, Steven Messina-Graham,[...]. Cell 2015
199
9


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.