Richard C Wang, Agata Smogorzewska, Titia de Lange. Cell 2004
Times Cited: 396
Times Cited: 396
Times Cited
Times Co-cited
Similarity
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Agnel Sfeir, Settapong T Kosiyatrakul, Dirk Hockemeyer, Sheila L MacRae, Jan Karlseder, Carl L Schildkraut, Titia de Lange. Cell 2009
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Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
Ylli Doksani, John Y Wu, Titia de Lange, Xiaowei Zhuang. Cell 2013
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Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
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Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops.
Anthony J Cesare, Jack D Griffith. Mol Cell Biol 2004
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RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.
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Control of telomere length by a trimming mechanism that involves generation of t-circles.
Hilda A Pickett, Anthony J Cesare, Rebecca L Johnston, Axel A Neumann, Roger R Reddel. EMBO J 2009
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DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
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DNA damage foci at dysfunctional telomeres.
Hiroyuki Takai, Agata Smogorzewska, Titia de Lange. Curr Biol 2003
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Alternative lengthening of telomeres: models, mechanisms and implications.
Anthony J Cesare, Roger R Reddel. Nat Rev Genet 2010
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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
Eros Lazzerini Denchi, Titia de Lange. Nature 2007
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TRF2 protects human telomeres from end-to-end fusions.
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
B van Steensel, A Smogorzewska, T de Lange. Cell 1998
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Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
Peng Wu, Hiroyuki Takai, Titia de Lange. Cell 2012
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Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.
T R Yeager, A A Neumann, A Englezou, L I Huschtscha, J R Noble, R R Reddel. Cancer Res 1999
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Telomere maintenance by recombination in human cells.
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Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
Roderick J O'Sullivan, Nausica Arnoult, Daniel H Lackner, Liana Oganesian, Candy Haggblom, Armelle Corpet, Genevieve Almouzni, Jan Karlseder. Nat Struct Mol Biol 2014
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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
Giulia B Celli, Titia de Lange. Nat Cell Biol 2005
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Telomeres shorten during ageing of human fibroblasts.
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T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang.
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Removal of shelterin reveals the telomere end-protection problem.
Agnel Sfeir, Titia de Lange. Science 2012
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Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Courtney A Lovejoy, Wendi Li, Steven Reisenweber, Supawat Thongthip, Joanne Bruno, Titia de Lange, Saurav De, John H J Petrini, Patricia A Sung, Maria Jasin,[...]. PLoS Genet 2012
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Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
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Pot1, the putative telomere end-binding protein in fission yeast and humans.
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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
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Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends.
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Telomere elongation in immortal human cells without detectable telomerase activity.
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Telomere protection by TPP1/POT1 requires tethering to TIN2.
Kaori K Takai, Tatsuya Kibe, Jill R Donigian, David Frescas, Titia de Lange. Mol Cell 2011
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TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
Grzegorz Sarek, Jean-Baptiste Vannier, Stephanie Panier, John H J Petrini, Simon J Boulton. Mol Cell 2015
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Apollo contributes to G overhang maintenance and protects leading-end telomeres.
Peng Wu, Megan van Overbeek, Sean Rooney, Titia de Lange. Mol Cell 2010
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Identification of human Rap1: implications for telomere evolution.
B Li, S Oestreich, T de Lange. Cell 2000
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The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats.
Nicole Fouché, Anthony J Cesare, Smaranda Willcox, Sezgin Ozgür, Sarah A Compton, Jack D Griffith. J Biol Chem 2006
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Altered telomeres in tumors with ATRX and DAXX mutations.
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An alternative pathway for yeast telomere maintenance rescues est1- senescence.
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A DNA damage checkpoint response in telomere-initiated senescence.
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14
A topological mechanism for TRF2-enhanced strand invasion.
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TRF2 promotes, remodels and protects telomeric Holliday junctions.
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TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres.
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Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.
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The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres.
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A two-step mechanism for TRF2-mediated chromosome-end protection.
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Keiji Okamoto, Cristina Bartocci, Iliana Ouzounov, Jolene K Diedrich, John R Yates, Eros Lazzerini Denchi. Nature 2013
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TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
Michal Zimmermann, Tatsuya Kibe, Shaheen Kabir, Titia de Lange. Genes Dev 2014
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Specific association of human telomerase activity with immortal cells and cancer.
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POT1 as a terminal transducer of TRF1 telomere length control.
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The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres.
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A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
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Telomeric localization of TRF2, a novel human telobox protein.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.