Richard C Wang, Agata Smogorzewska, Titia de Lange. Cell 2004
Times Cited: 401
Times Cited: 401
Times Cited
Times Co-cited
Similarity
Mammalian telomeres end in a large duplex loop.
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
J D Griffith, L Comeau, S Rosenfield, R M Stansel, A Bianchi, H Moss, T de Lange. Cell 1999
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Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
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Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation.
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Shelterin: the protein complex that shapes and safeguards human telomeres.
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Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops.
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DNA damage foci at dysfunctional telomeres.
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TRF2 protects human telomeres from end-to-end fusions.
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Control of telomere length by a trimming mechanism that involves generation of t-circles.
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DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
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Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
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Telomere maintenance by recombination in human cells.
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DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
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Telomeric 3' overhangs derive from resection by Exo1 and Apollo and fill-in by POT1b-associated CST.
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Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines.
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Pot1, the putative telomere end-binding protein in fission yeast and humans.
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Telomeres shorten during ageing of human fibroblasts.
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Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1.
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Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal.
Agnel Sfeir, Shaheen Kabir, Megan van Overbeek, Giulia B Celli, Titia de Lange. Science 2010
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Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
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Removal of shelterin reveals the telomere end-protection problem.
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T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang.
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Identification of human Rap1: implications for telomere evolution.
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Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2.
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TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.
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Telomere protection by TPP1/POT1 requires tethering to TIN2.
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TRF2 promotes, remodels and protects telomeric Holliday junctions.
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A DNA damage checkpoint response in telomere-initiated senescence.
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A topological mechanism for TRF2-enhanced strand invasion.
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TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres.
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Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice.
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The basic domain of TRF2 directs binding to DNA junctions irrespective of the presence of TTAGGG repeats.
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A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins.
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The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeres.
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A two-step mechanism for TRF2-mediated chromosome-end protection.
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Altered telomeres in tumors with ATRX and DAXX mutations.
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Specific association of human telomerase activity with immortal cells and cancer.
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TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage.
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POT1 as a terminal transducer of TRF1 telomere length control.
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Apollo contributes to G overhang maintenance and protects leading-end telomeres.
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Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.
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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2.
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Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.