Structural insights into the regulation and the activation mechanism of mammalian guanylyl cyclases.
Pius S Padayatti, Priyaranjan Pattanaik, Xiaolei Ma, Focco van den Akker. Pharmacol Ther 2004
Times Cited: 41
Times Cited: 41
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Structure, regulation, and function of mammalian membrane guanylyl cyclase receptors, with a focus on guanylyl cyclase-A.
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Expression and characterization of the catalytic domains of soluble guanylate cyclase: interaction with the heme domain.
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Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction.
Haruo Ogawa, Yue Qiu, Craig M Ogata, Kunio S Misono. J Biol Chem 2004
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The protein kinase domain of the ANP receptor is required for signaling.
M Chinkers, D L Garbers. Science 1989
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Guanylyl cyclases and signaling by cyclic GMP.
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
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Soluble guanylyl cyclase: more secrets revealed.
Anastasia Pyriochou, Andreas Papapetropoulos. Cell Signal 2005
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Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS.
J J Tesmer, R K Sunahara, A G Gilman, S R Sprang. Science 1997
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Natriuretic peptides, their receptors, and cyclic guanosine monophosphate-dependent signaling functions.
Lincoln R Potter, Sarah Abbey-Hosch, Deborah M Dickey. Endocr Rev 2006
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Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases.
R K Sunahara, A Beuve, J J Tesmer, S R Sprang, D L Garbers, A G Gilman. J Biol Chem 1998
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Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase.
Fu-Jung Chang, Scott Lemme, Qian Sun, Roger K Sunahara, Annie Beuve. J Biol Chem 2005
Fu-Jung Chang, Scott Lemme, Qian Sun, Roger K Sunahara, Annie Beuve. J Biol Chem 2005
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Atrial natriuretic peptide-dependent photolabeling of a regulatory ATP-binding site on the natriuretic peptide receptor-A.
Simon Joubert, Christian Jossart, Normand McNicoll, André De Léan. FEBS J 2005
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Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins.
Lakshminarayan M Iyer, Vivek Anantharaman, L Aravind. BMC Genomics 2003
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Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases.
Patricia Pellicena, David S Karow, Elizabeth M Boon, Michael A Marletta, John Kuriyan. Proc Natl Acad Sci U S A 2004
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A disulfide-bridged mutant of natriuretic peptide receptor-A displays constitutive activity. Role of receptor dimerization in signal transduction.
J Labrecque, N Mc Nicoll, M Marquis, A De Léan. J Biol Chem 1999
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A receptor guanylyl cyclase expressed specifically in olfactory sensory neurons.
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High and low gain switches for regulation of cAMP efflux concentration: distinct roles for particulate GC- and soluble GC-cGMP-PDE3 signaling in rabbit atria.
Jin Fu Wen, Xun Cui, Jing Yu Jin, Soo Mi Kim, Sung Zoo Kim, Suhn Hee Kim, Ho Sub Lee, Kyung Woo Cho. Circ Res 2004
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Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy.
Eiki Takimoto, Hunter C Champion, Manxiang Li, Diego Belardi, Shuxun Ren, E Rene Rodriguez, Djahida Bedja, Kathleen L Gabrielson, Yibin Wang, David A Kass. Nat Med 2005
Eiki Takimoto, Hunter C Champion, Manxiang Li, Diego Belardi, Shuxun Ren, E Rene Rodriguez, Djahida Bedja, Kathleen L Gabrielson, Yibin Wang, David A Kass. Nat Med 2005
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Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes.
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Catalytic mechanism of the adenylyl and guanylyl cyclases: modeling and mutational analysis.
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Paul Emsley, Kevin Cowtan. Acta Crystallogr D Biol Crystallogr 2004
Paul Emsley, Kevin Cowtan. Acta Crystallogr D Biol Crystallogr 2004
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The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme.
Ivo Tews, Felix Findeisen, Irmgard Sinning, Anita Schultz, Joachim E Schultz, Jürgen U Linder. Science 2005
Ivo Tews, Felix Findeisen, Irmgard Sinning, Anita Schultz, Joachim E Schultz, Jürgen U Linder. Science 2005
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Structure of the adenylyl cyclase catalytic core.
G Zhang, Y Liu, A E Ruoho, J H Hurley. Nature 1997
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Femtomolar sensitivity of a NO sensor from Clostridium botulinum.
Pierre Nioche, Vladimir Berka, Julia Vipond, Nigel Minton, Ah-Lim Tsai, C S Raman. Science 2004
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Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor.
L R Potter, T Hunter. Mol Cell Biol 1998
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12
NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism.
Xiaolei Ma, Nazish Sayed, Annie Beuve, Focco van den Akker. EMBO J 2007
Xiaolei Ma, Nazish Sayed, Annie Beuve, Focco van den Akker. EMBO J 2007
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Structural and functional characterization of the dimerization region of soluble guanylyl cyclase.
Zongmin Zhou, Steffen Gross, Charis Roussos, Sabine Meurer, Werner Müller-Esterl, Andreas Papapetropoulos. J Biol Chem 2004
Zongmin Zhou, Steffen Gross, Charis Roussos, Sabine Meurer, Werner Müller-Esterl, Andreas Papapetropoulos. J Biol Chem 2004
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Crystal structure of the guanylyl cyclase Cya2.
Annika Rauch, Martina Leipelt, Michael Russwurm, Clemens Steegborn. Proc Natl Acad Sci U S A 2008
Annika Rauch, Martina Leipelt, Michael Russwurm, Clemens Steegborn. Proc Natl Acad Sci U S A 2008
12
Mechanisms of ligand discrimination by heme proteins.
Rinku Jain, Michael K Chan. J Biol Inorg Chem 2003
Rinku Jain, Michael K Chan. J Biol Inorg Chem 2003
9
Agonistic induction of a covalent dimer in a mutant of natriuretic peptide receptor-A documents a juxtamembrane interaction that accompanies receptor activation.
J Labrecque, J Deschênes, N McNicoll, A De Léan. J Biol Chem 2001
J Labrecque, J Deschênes, N McNicoll, A De Léan. J Biol Chem 2001
13
Dual regulation of atrial natriuretic factor-dependent guanylate cyclase activity by ATP.
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9
Evolution of the membrane guanylate cyclase transduction system.
Rameshwar K Sharma. Mol Cell Biochem 2002
Rameshwar K Sharma. Mol Cell Biochem 2002
9
Ligand binding-dependent limited proteolysis of the atrial natriuretic peptide receptor: juxtamembrane hinge structure essential for transmembrane signal transduction.
X Huo, T Abe, K S Misono. Biochemistry 1999
X Huo, T Abe, K S Misono. Biochemistry 1999
9
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Characterization of particulate and soluble guanylate cyclases from rat lung.
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9
Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases.
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9
Nitric oxide regulates cardiac Ca2+ current. Involvement of cGMP-inhibited and cGMP-stimulated phosphodiesterases through guanylyl cyclase activation.
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mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module.
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Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes.
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Jeremy Wechsler, Young-Hun Choi, Judith Krall, Faiyaz Ahmad, Vincent C Manganiello, Matthew A Movsesian. J Biol Chem 2002
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Differential relaxing responses to particulate or soluble guanylyl cyclase activation on endothelial cells: a mechanism dependent on PKG-I alpha activation by NO/cGMP.
F J Rivero-Vilches, S de Frutos, M Saura, D Rodriguez-Puyol, M Rodriguez-Puyol. Am J Physiol Cell Physiol 2003
F J Rivero-Vilches, S de Frutos, M Saura, D Rodriguez-Puyol, M Rodriguez-Puyol. Am J Physiol Cell Physiol 2003
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In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.
T C Rich, T E Tse, J G Rohan, J Schaack, J W Karpen. J Gen Physiol 2001
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Cyclic GMP phosphodiesterases and regulation of smooth muscle function.
Sergei D Rybalkin, Chen Yan, Karin E Bornfeldt, Joseph A Beavo. Circ Res 2003
Sergei D Rybalkin, Chen Yan, Karin E Bornfeldt, Joseph A Beavo. Circ Res 2003
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cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists.
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Tissue distribution of phosphodiesterase families and the effects of sildenafil on tissue cyclic nucleotides, platelet function, and the contractile responses of trabeculae carneae and aortic rings in vitro.
R M Wallis, J D Corbin, S H Francis, P Ellis. Am J Cardiol 1999
R M Wallis, J D Corbin, S H Francis, P Ellis. Am J Cardiol 1999
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Cardiac phosphodiesterase 5 (cGMP-specific) modulates beta-adrenergic signaling in vivo and is down-regulated in heart failure.
H Senzaki, C J Smith, G J Juang, T Isoda, S P Mayer, A Ohler, N Paolocci, G F Tomaselli, J M Hare, D A Kass. FASEB J 2001
H Senzaki, C J Smith, G J Juang, T Isoda, S P Mayer, A Ohler, N Paolocci, G F Tomaselli, J M Hare, D A Kass. FASEB J 2001
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Functional characterization of nitric oxide and YC-1 activation of soluble guanylyl cyclase: structural implication for the YC-1 binding site?
Maria Lamothe, Fu-Jung Chang, Nataliya Balashova, Roman Shirokov, Annie Beuve. Biochemistry 2004
Maria Lamothe, Fu-Jung Chang, Nataliya Balashova, Roman Shirokov, Annie Beuve. Biochemistry 2004
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Kinetic characterization of atrial natriuretic factor-sensitive particulate guanylate cyclase.
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Synergistic activation of soluble guanylate cyclase by YC-1 and carbon monoxide: implications for the role of cleavage of the iron-histidine bond during activation by nitric oxide.
J R Stone, M A Marletta. Chem Biol 1998
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Refinement of macromolecular structures by the maximum-likelihood method.
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9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.