P Thomas, Y Pang, E J Filardo, J Dong. Endocrinology 2005
Times Cited: 1060
Times Cited: 1060
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A transmembrane intracellular estrogen receptor mediates rapid cell signaling.
Chetana M Revankar, Daniel F Cimino, Larry A Sklar, Jeffrey B Arterburn, Eric R Prossnitz. Science 2005
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64
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF.
E J Filardo, J A Quinn, K I Bland, A R Frackelton. Mol Endocrinol 2000
E J Filardo, J A Quinn, K I Bland, A R Frackelton. Mol Endocrinol 2000
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Virtual and biomolecular screening converge on a selective agonist for GPR30.
Cristian G Bologa, Chetana M Revankar, Susan M Young, Bruce S Edwards, Jeffrey B Arterburn, Alexander S Kiselyov, Matthew A Parker, Sergey E Tkachenko, Nikolay P Savchuck, Larry A Sklar,[...]. Nat Chem Biol 2006
Cristian G Bologa, Chetana M Revankar, Susan M Young, Bruce S Edwards, Jeffrey B Arterburn, Alexander S Kiselyov, Matthew A Parker, Sergey E Tkachenko, Nikolay P Savchuck, Larry A Sklar,[...]. Nat Chem Biol 2006
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Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer.
C Carmeci, D A Thompson, H Z Ring, U Francke, R J Weigel. Genomics 1997
C Carmeci, D A Thompson, H Z Ring, U Francke, R J Weigel. Genomics 1997
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The G-protein-coupled estrogen receptor GPER in health and disease.
Eric R Prossnitz, Matthias Barton. Nat Rev Endocrinol 2011
Eric R Prossnitz, Matthias Barton. Nat Rev Endocrinol 2011
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Regulatory role of G protein-coupled estrogen receptor for vascular function and obesity.
Elvira Haas, Indranil Bhattacharya, Eugen Brailoiu, Marlen Damjanović, G Cristina Brailoiu, Xin Gao, Laurence Mueller-Guerre, Nicole A Marjon, André Gut, Roberta Minotti,[...]. Circ Res 2009
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In vivo effects of a GPR30 antagonist.
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18
Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity.
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16
Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis.
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16
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Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.
Ulrika E A Mårtensson, S Albert Salehi, Sara Windahl, Maria F Gomez, Karl Swärd, Joanna Daszkiewicz-Nilsson, Anna Wendt, Niklas Andersson, Per Hellstrand, Per-Olof Grände,[...]. Endocrinology 2009
Ulrika E A Mårtensson, S Albert Salehi, Sara Windahl, Maria F Gomez, Karl Swärd, Joanna Daszkiewicz-Nilsson, Anna Wendt, Niklas Andersson, Per Hellstrand, Per-Olof Grände,[...]. Endocrinology 2009
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Cloning of a novel receptor expressed in rat prostate and ovary.
G G Kuiper, E Enmark, M Pelto-Huikko, S Nilsson, J A Gustafsson. Proc Natl Acad Sci U S A 1996
G G Kuiper, E Enmark, M Pelto-Huikko, S Nilsson, J A Gustafsson. Proc Natl Acad Sci U S A 1996
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G protein-coupled estrogen receptor-selective ligands modulate endometrial tumor growth.
Whitney K Petrie, Megan K Dennis, Chelin Hu, Donghai Dai, Jeffrey B Arterburn, Harriet O Smith, Helen J Hathaway, Eric R Prossnitz. Obstet Gynecol Int 2013
Whitney K Petrie, Megan K Dennis, Chelin Hu, Donghai Dai, Jeffrey B Arterburn, Harriet O Smith, Helen J Hathaway, Eric R Prossnitz. Obstet Gynecol Int 2013
13
International Union of Basic and Clinical Pharmacology. XCVII. G Protein-Coupled Estrogen Receptor and Its Pharmacologic Modulators.
Eric R Prossnitz, Jeffrey B Arterburn. Pharmacol Rev 2015
Eric R Prossnitz, Jeffrey B Arterburn. Pharmacol Rev 2015
13
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.
Lidia Albanito, Antonio Madeo, Rosamaria Lappano, Adele Vivacqua, Vittoria Rago, Amalia Carpino, Tudor I Oprea, Eric R Prossnitz, Anna Maria Musti, Sebastiano Andò,[...]. Cancer Res 2007
Lidia Albanito, Antonio Madeo, Rosamaria Lappano, Adele Vivacqua, Vittoria Rago, Amalia Carpino, Tudor I Oprea, Eric R Prossnitz, Anna Maria Musti, Sebastiano Andò,[...]. Cancer Res 2007
13
Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives.
Matthias Barton, Edward J Filardo, Stephen J Lolait, Peter Thomas, Marcello Maggiolini, Eric R Prossnitz. J Steroid Biochem Mol Biol 2018
Matthias Barton, Edward J Filardo, Stephen J Lolait, Peter Thomas, Marcello Maggiolini, Eric R Prossnitz. J Steroid Biochem Mol Biol 2018
13
Estrogen signaling through the transmembrane G protein-coupled receptor GPR30.
Eric R Prossnitz, Jeffrey B Arterburn, Harriet O Smith, Tudor I Oprea, Larry A Sklar, Helen J Hathaway. Annu Rev Physiol 2008
Eric R Prossnitz, Jeffrey B Arterburn, Harriet O Smith, Tudor I Oprea, Larry A Sklar, Helen J Hathaway. Annu Rev Physiol 2008
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Does GPER Really Function as a G Protein-Coupled Estrogen Receptor in vivo?
Jing Luo, Dongmin Liu. Front Endocrinol (Lausanne) 2020
Jing Luo, Dongmin Liu. Front Endocrinol (Lausanne) 2020
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GPR30/GPER1: searching for a role in estrogen physiology.
Björn Olde, L M Fredrik Leeb-Lundberg. Trends Endocrinol Metab 2009
Björn Olde, L M Fredrik Leeb-Lundberg. Trends Endocrinol Metab 2009
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Mechanisms of estrogen action.
S Nilsson, S Mäkelä, E Treuter, M Tujague, J Thomsen, G Andersson, E Enmark, K Pettersson, M Warner, J A Gustafsson. Physiol Rev 2001
S Nilsson, S Mäkelä, E Treuter, M Tujague, J Thomsen, G Andersson, E Enmark, K Pettersson, M Warner, J A Gustafsson. Physiol Rev 2001
10
G protein-coupled receptor 30 localizes to the endoplasmic reticulum and is not activated by estradiol.
Christiane Otto, Beate Rohde-Schulz, Gilda Schwarz, Iris Fuchs, Mario Klewer, Dominic Brittain, Gernot Langer, Benjamin Bader, Katja Prelle, Reinhard Nubbemeyer,[...]. Endocrinology 2008
Christiane Otto, Beate Rohde-Schulz, Gilda Schwarz, Iris Fuchs, Mario Klewer, Dominic Brittain, Gernot Langer, Benjamin Bader, Katja Prelle, Reinhard Nubbemeyer,[...]. Endocrinology 2008
10
Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats.
Anne M Deschamps, Elizabeth Murphy. Am J Physiol Heart Circ Physiol 2009
Anne M Deschamps, Elizabeth Murphy. Am J Physiol Heart Circ Physiol 2009
10
Estrogen biology: new insights into GPER function and clinical opportunities.
Eric R Prossnitz, Matthias Barton. Mol Cell Endocrinol 2014
Eric R Prossnitz, Matthias Barton. Mol Cell Endocrinol 2014
10
Discovery of three novel G-protein-coupled receptor genes.
B F O'Dowd, T Nguyen, A Marchese, R Cheng, K R Lynch, H H Heng, L F Kolakowski, S R George. Genomics 1998
B F O'Dowd, T Nguyen, A Marchese, R Cheng, K R Lynch, H H Heng, L F Kolakowski, S R George. Genomics 1998
10
GPER mediates activation of HIF1α/VEGF signaling by estrogens.
Ernestina Marianna De Francesco, Michele Pellegrino, Maria Francesca Santolla, Rosamaria Lappano, Emilia Ricchio, Sergio Abonante, Marcello Maggiolini. Cancer Res 2014
Ernestina Marianna De Francesco, Michele Pellegrino, Maria Francesca Santolla, Rosamaria Lappano, Emilia Ricchio, Sergio Abonante, Marcello Maggiolini. Cancer Res 2014
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Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane.
E Filardo, J Quinn, Y Pang, C Graeber, S Shaw, J Dong, P Thomas. Endocrinology 2007
E Filardo, J Quinn, Y Pang, C Graeber, S Shaw, J Dong, P Thomas. Endocrinology 2007
10
17β-Estradiol and Agonism of G-protein-Coupled Estrogen Receptor Enhance Hippocampal Memory via Different Cell-Signaling Mechanisms.
Jaekyoon Kim, Julia S Szinte, Marissa I Boulware, Karyn M Frick. J Neurosci 2016
Jaekyoon Kim, Julia S Szinte, Marissa I Boulware, Karyn M Frick. J Neurosci 2016
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Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER.
Eric R Prossnitz, Matthias Barton. Prostaglandins Other Lipid Mediat 2009
Eric R Prossnitz, Matthias Barton. Prostaglandins Other Lipid Mediat 2009
9
Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest.
Q K Y Chan, H-M Lam, C-F Ng, A Y Y Lee, E S Y Chan, H-K Ng, S-M Ho, K-M Lau. Cell Death Differ 2010
Q K Y Chan, H-M Lam, C-F Ng, A Y Y Lee, E S Y Chan, H-K Ng, S-M Ho, K-M Lau. Cell Death Differ 2010
9
Chronic treatment with the G protein-coupled receptor 30 agonist G-1 decreases blood pressure in ovariectomized mRen2.Lewis rats.
Sarah Hoffmann Lindsey, Jonathan A Cohen, K Bridget Brosnihan, Patricia E Gallagher, Mark C Chappell. Endocrinology 2009
Sarah Hoffmann Lindsey, Jonathan A Cohen, K Bridget Brosnihan, Patricia E Gallagher, Mark C Chappell. Endocrinology 2009
9
9
GPR30 contributes to estrogen-induced thymic atrophy.
Chunhe Wang, Babak Dehghani, I Jack Magrisso, Elizabeth A Rick, Edna Bonhomme, David B Cody, Laura A Elenich, Sandhya Subramanian, Stephanie J Murphy, Martin J Kelly,[...]. Mol Endocrinol 2008
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9
Down-modulation of the G-protein-coupled estrogen receptor, GPER, from the cell surface occurs via a trans-Golgi-proteasome pathway.
Shi-Bin Cheng, Jeffrey A Quinn, Carl T Graeber, Edward J Filardo. J Biol Chem 2011
Shi-Bin Cheng, Jeffrey A Quinn, Carl T Graeber, Edward J Filardo. J Biol Chem 2011
9
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta.
G G Kuiper, B Carlsson, K Grandien, E Enmark, J Häggblad, S Nilsson, J A Gustafsson. Endocrinology 1997
G G Kuiper, B Carlsson, K Grandien, E Enmark, J Häggblad, S Nilsson, J A Gustafsson. Endocrinology 1997
9
Estrogen receptors: how do they signal and what are their targets.
Nina Heldring, Ashley Pike, Sandra Andersson, Jason Matthews, Guojun Cheng, Johan Hartman, Michel Tujague, Anders Ström, Eckardt Treuter, Margaret Warner,[...]. Physiol Rev 2007
Nina Heldring, Ashley Pike, Sandra Andersson, Jason Matthews, Guojun Cheng, Johan Hartman, Michel Tujague, Anders Ström, Eckardt Treuter, Margaret Warner,[...]. Physiol Rev 2007
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Nature of functional estrogen receptors at the plasma membrane.
Ali Pedram, Mahnaz Razandi, Ellis R Levin. Mol Endocrinol 2006
Ali Pedram, Mahnaz Razandi, Ellis R Levin. Mol Endocrinol 2006
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Involvement of estrogen receptor variant ER-alpha36, not GPR30, in nongenomic estrogen signaling.
Lianguo Kang, Xintian Zhang, Yan Xie, Yaping Tu, Dong Wang, Zhenming Liu, Zhao-Yi Wang. Mol Endocrinol 2010
Lianguo Kang, Xintian Zhang, Yan Xie, Yaping Tu, Dong Wang, Zhenming Liu, Zhao-Yi Wang. Mol Endocrinol 2010
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Identification, cloning, and expression of human estrogen receptor-alpha36, a novel variant of human estrogen receptor-alpha66.
Zhaoyi Wang, Xintian Zhang, Peng Shen, Brian W Loggie, Yunchao Chang, Thomas F Deuel. Biochem Biophys Res Commun 2005
Zhaoyi Wang, Xintian Zhang, Peng Shen, Brian W Loggie, Yunchao Chang, Thomas F Deuel. Biochem Biophys Res Commun 2005
9
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption.
Peter Thomas, Jing Dong. J Steroid Biochem Mol Biol 2006
Peter Thomas, Jing Dong. J Steroid Biochem Mol Biol 2006
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Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology.
Edward J Filardo, Peter Thomas. Endocrinology 2012
Edward J Filardo, Peter Thomas. Endocrinology 2012
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Cloning of human cDNA encoding a novel heptahelix receptor expressed in Burkitt's lymphoma and widely distributed in brain and peripheral tissues.
C Owman, P Blay, C Nilsson, S J Lolait. Biochem Biophys Res Commun 1996
C Owman, P Blay, C Nilsson, S J Lolait. Biochem Biophys Res Commun 1996
9
What have we learned about GPER function in physiology and disease from knockout mice?
Eric R Prossnitz, Helen J Hathaway. J Steroid Biochem Mol Biol 2015
Eric R Prossnitz, Helen J Hathaway. J Steroid Biochem Mol Biol 2015
9
Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells.
Lei Li, M Page Haynes, Jeffrey R Bender. Proc Natl Acad Sci U S A 2003
Lei Li, M Page Haynes, Jeffrey R Bender. Proc Natl Acad Sci U S A 2003
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G-Protein Coupled Estrogen Receptor in Breast Cancer.
Li-Han Hsu, Nei-Min Chu, Yung-Feng Lin, Shu-Huei Kao. Int J Mol Sci 2019
Li-Han Hsu, Nei-Min Chu, Yung-Feng Lin, Shu-Huei Kao. Int J Mol Sci 2019
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G Protein-Coupled Estrogen Receptor: A Potential Therapeutic Target in Cancer.
Shen Xu, Shan Yu, Daming Dong, Leo Tsz On Lee. Front Endocrinol (Lausanne) 2019
Shen Xu, Shan Yu, Daming Dong, Leo Tsz On Lee. Front Endocrinol (Lausanne) 2019
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Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues.
Georgina G J Hazell, Song T Yao, James A Roper, Eric R Prossnitz, Anne-Marie O'Carroll, Stephen J Lolait. J Endocrinol 2009
Georgina G J Hazell, Song T Yao, James A Roper, Eric R Prossnitz, Anne-Marie O'Carroll, Stephen J Lolait. J Endocrinol 2009
8
Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system.
Eugen Brailoiu, Siok L Dun, G Cristina Brailoiu, Keisuke Mizuo, Larry A Sklar, Tudor I Oprea, Eric R Prossnitz, Nae J Dun. J Endocrinol 2007
Eugen Brailoiu, Siok L Dun, G Cristina Brailoiu, Keisuke Mizuo, Larry A Sklar, Tudor I Oprea, Eric R Prossnitz, Nae J Dun. J Endocrinol 2007
8
G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane.
Takeshi Funakoshi, Akie Yanai, Koh Shinoda, Michio M Kawano, Yoichi Mizukami. Biochem Biophys Res Commun 2006
Takeshi Funakoshi, Akie Yanai, Koh Shinoda, Michio M Kawano, Yoichi Mizukami. Biochem Biophys Res Commun 2006
8
Role of GPER in estrogen-dependent nitric oxide formation and vasodilation.
Natalie C Fredette, Matthias R Meyer, Eric R Prossnitz. J Steroid Biochem Mol Biol 2018
Natalie C Fredette, Matthias R Meyer, Eric R Prossnitz. J Steroid Biochem Mol Biol 2018
11
A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogen- and antiestrogen-dependent membrane-initiated mitogenic signaling.
Zhaoyi Wang, Xintian Zhang, Peng Shen, Brian W Loggie, Yunchao Chang, Thomas F Deuel. Proc Natl Acad Sci U S A 2006
Zhaoyi Wang, Xintian Zhang, Peng Shen, Brian W Loggie, Yunchao Chang, Thomas F Deuel. Proc Natl Acad Sci U S A 2006
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.