A citation-based method for searching scientific literature

J A Hardy, G A Higgins. Science 1992
Times Cited: 4189







List of co-cited articles
795 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



The amyloid hypothesis of Alzheimer's disease at 25 years.
Dennis J Selkoe, John Hardy. EMBO Mol Med 2016
16

The antibody aducanumab reduces Aβ plaques in Alzheimer's disease.
Jeff Sevigny, Ping Chiao, Thierry Bussière, Paul H Weinreb, Leslie Williams, Marcel Maier, Robert Dunstan, Stephen Salloway, Tianle Chen, Yan Ling,[...]. Nature 2016
16


NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Clifford R Jack, David A Bennett, Kaj Blennow, Maria C Carrillo, Billy Dunn, Samantha Budd Haeberlein, David M Holtzman, William Jagust, Frank Jessen, Jason Karlawish,[...]. Alzheimers Dement 2018
12


Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.
Salvatore Oddo, Antonella Caccamo, Jason D Shepherd, M Paul Murphy, Todd E Golde, Rakez Kayed, Raju Metherate, Mark P Mattson, Yama Akbari, Frank M LaFerla. Neuron 2003
10

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers.
Clifford R Jack, David S Knopman, William J Jagust, Ronald C Petersen, Michael W Weiner, Paul S Aisen, Leslie M Shaw, Prashanthi Vemuri, Heather J Wiste, Stephen D Weigand,[...]. Lancet Neurol 2013
10

Neuroinflammation in Alzheimer's disease.
Michael T Heneka, Monica J Carson, Joseph El Khoury, Gary E Landreth, Frederic Brosseron, Douglas L Feinstein, Andreas H Jacobs, Tony Wyss-Coray, Javier Vitorica, Richard M Ransohoff,[...]. Lancet Neurol 2015
9


Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.
R Sherrington, E I Rogaev, Y Liang, E A Rogaeva, G Levesque, M Ikeda, H Chi, C Lin, G Li, K Holman,[...]. Nature 1995
8

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism.
Samuel I A Cohen, Sara Linse, Leila M Luheshi, Erik Hellstrand, Duncan A White, Luke Rajah, Daniel E Otzen, Michele Vendruscolo, Christopher M Dobson, Tuomas P J Knowles. Proc Natl Acad Sci U S A 2013
777
8

Donanemab in Early Alzheimer's Disease.
Mark A Mintun, Albert C Lo, Cynthia Duggan Evans, Alette M Wessels, Paul A Ardayfio, Scott W Andersen, Sergey Shcherbinin, JonDavid Sparks, John R Sims, Miroslaw Brys,[...]. N Engl J Med 2021
168
8


Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
A Goate, M C Chartier-Harlin, M Mullan, J Brown, F Crawford, L Fidani, L Giuffra, A Haynes, N Irving, L James. Nature 1991
7

TREM2 variants in Alzheimer's disease.
Rita Guerreiro, Aleksandra Wojtas, Jose Bras, Minerva Carrasquillo, Ekaterina Rogaeva, Elisa Majounie, Carlos Cruchaga, Celeste Sassi, John S K Kauwe, Steven Younkin,[...]. N Engl J Med 2013
7

Variant of TREM2 associated with the risk of Alzheimer's disease.
Thorlakur Jonsson, Hreinn Stefansson, Stacy Steinberg, Ingileif Jonsdottir, Palmi V Jonsson, Jon Snaedal, Sigurbjorn Bjornsson, Johanna Huttenlocher, Allan I Levey, James J Lah,[...]. N Engl J Med 2013
7

Phases of A beta-deposition in the human brain and its relevance for the development of AD.
Dietmar R Thal, Udo Rüb, Mario Orantes, Heiko Braak. Neurology 2002
7

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.
J Lewis, D W Dickson, W L Lin, L Chisholm, A Corral, G Jones, S H Yen, N Sahara, L Skipper, D Yager,[...]. Science 2001
7

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
Peter T Nelson, Irina Alafuzoff, Eileen H Bigio, Constantin Bouras, Heiko Braak, Nigel J Cairns, Rudolph J Castellani, Barbara J Crain, Peter Davies, Kelly Del Tredici,[...]. J Neuropathol Exp Neurol 2012
7

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.
I Grundke-Iqbal, K Iqbal, Y C Tung, M Quinlan, H M Wisniewski, L I Binder. Proc Natl Acad Sci U S A 1986
6


Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
Brian W Kunkle, Benjamin Grenier-Boley, Rebecca Sims, Joshua C Bis, Vincent Damotte, Adam C Naj, Anne Boland, Maria Vronskaya, Sven J van der Lee, Alexandre Amlie-Wolf,[...]. Nat Genet 2019
838
6

Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Stephen Salloway, Reisa Sperling, Nick C Fox, Kaj Blennow, William Klunk, Murray Raskind, Marwan Sabbagh, Lawrence S Honig, Anton P Porsteinsson, Steven Ferris,[...]. N Engl J Med 2014
6

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue.
Marius Kollmer, William Close, Leonie Funk, Jay Rasmussen, Aref Bsoul, Angelika Schierhorn, Matthias Schmidt, Christina J Sigurdson, Mathias Jucker, Marcus Fändrich. Nat Commun 2019
198
6

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.
Ganesh M Shankar, Shaomin Li, Tapan H Mehta, Amaya Garcia-Munoz, Nina E Shepardson, Imelda Smith, Francesca M Brett, Michael A Farrell, Michael J Rowan, Cynthia A Lemere,[...]. Nat Med 2008
6

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E H Corder, A M Saunders, W J Strittmatter, D E Schmechel, P C Gaskell, G W Small, A D Roses, J L Haines, M A Pericak-Vance. Science 1993
6

Clinical and biomarker changes in dominantly inherited Alzheimer's disease.
Randall J Bateman, Chengjie Xiong, Tammie L S Benzinger, Anne M Fagan, Alison Goate, Nick C Fox, Daniel S Marcus, Nigel J Cairns, Xianyun Xie, Tyler M Blazey,[...]. N Engl J Med 2012
6

Alzheimer's disease.
Philip Scheltens, Bart De Strooper, Miia Kivipelto, Henne Holstege, Gael Chételat, Charlotte E Teunissen, Jeffrey Cummings, Wiesje M van der Flier. Lancet 2021
197
6

A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.
Thorlakur Jonsson, Jasvinder K Atwal, Stacy Steinberg, Jon Snaedal, Palmi V Jonsson, Sigurbjorn Bjornsson, Hreinn Stefansson, Patrick Sulem, Daniel Gudbjartsson, Janice Maloney,[...]. Nature 2012
6

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation.
Zhuohao He, Jing L Guo, Jennifer D McBride, Sneha Narasimhan, Hyesung Kim, Lakshmi Changolkar, Bin Zhang, Ronald J Gathagan, Cuiyong Yue, Christopher Dengler,[...]. Nat Med 2018
256
6

The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease.
Guy M McKhann, David S Knopman, Howard Chertkow, Bradley T Hyman, Clifford R Jack, Claudia H Kawas, William E Klunk, Walter J Koroshetz, Jennifer J Manly, Richard Mayeux,[...]. Alzheimers Dement 2011
6

Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease.
Gary P Morris, Ian A Clark, Bryce Vissel. Acta Neuropathol Commun 2014
255
5

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.
Holly Oakley, Sarah L Cole, Sreemathi Logan, Erika Maus, Pei Shao, Jeffery Craft, Angela Guillozet-Bongaarts, Masuo Ohno, John Disterhoft, Linda Van Eldik,[...]. J Neurosci 2006
5

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease.
Russell H Swerdlow, Shaharyar M Khan. Med Hypotheses 2004
450
5


Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
L A Farrer, L A Cupples, J L Haines, B Hyman, W A Kukull, R Mayeux, R H Myers, M A Pericak-Vance, N Risch, C M van Duijn. JAMA 1997
5

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis.
Bob Olsson, Ronald Lautner, Ulf Andreasson, Annika Öhrfelt, Erik Portelius, Maria Bjerke, Mikko Hölttä, Christoffer Rosén, Caroline Olsson, Gabrielle Strobel,[...]. Lancet Neurol 2016
912
5

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
Denise Harold, Richard Abraham, Paul Hollingworth, Rebecca Sims, Amy Gerrish, Marian L Hamshere, Jaspreet Singh Pahwa, Valentina Moskvina, Kimberley Dowzell, Amy Williams,[...]. Nat Genet 2009
5

Amyloid precursor protein processing and Alzheimer's disease.
Richard J O'Brien, Philip C Wong. Annu Rev Neurosci 2011
909
5

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.
Dominic M Walsh, Igor Klyubin, Julia V Fadeeva, William K Cullen, Roger Anwyl, Michael S Wolfe, Michael J Rowan, Dennis J Selkoe. Nature 2002
5

Dementia prevention, intervention, and care: 2020 report of the Lancet Commission.
Gill Livingston, Jonathan Huntley, Andrew Sommerlad, David Ames, Clive Ballard, Sube Banerjee, Carol Brayne, Alistair Burns, Jiska Cohen-Mansfield, Claudia Cooper,[...]. Lancet 2020
5

A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aβ protofibril antibody.
Chad J Swanson, Yong Zhang, Shobha Dhadda, Jinping Wang, June Kaplow, Robert Y K Lai, Lars Lannfelt, Heather Bradley, Martin Rabe, Akihiko Koyama,[...]. Alzheimers Res Ther 2021
73
6

Inflammation and Alzheimer's disease.
H Akiyama, S Barger, S Barnum, B Bradt, J Bauer, G M Cole, N R Cooper, P Eikelenboom, M Emmerling, B L Fiebich,[...]. Neurobiol Aging 2000
5

Alzheimer's disease drug development pipeline: 2019.
Jeffrey Cummings, Garam Lee, Aaron Ritter, Marwan Sabbagh, Kate Zhong. Alzheimers Dement (N Y) 2019
334
5

Immune attack: the role of inflammation in Alzheimer disease.
Frank L Heppner, Richard M Ransohoff, Burkhard Becher. Nat Rev Neurosci 2015
5

Alzheimer's disease drug-development pipeline: few candidates, frequent failures.
Jeffrey L Cummings, Travis Morstorf, Kate Zhong. Alzheimers Res Ther 2014
921
5

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.
Hadas Keren-Shaul, Amit Spinrad, Assaf Weiner, Orit Matcovitch-Natan, Raz Dvir-Szternfeld, Tyler K Ulland, Eyal David, Kuti Baruch, David Lara-Astaiso, Beata Toth,[...]. Cell 2017
5

Amyloid plaque core protein in Alzheimer disease and Down syndrome.
C L Masters, G Simms, N A Weinman, G Multhaup, B L McDonald, K Beyreuther. Proc Natl Acad Sci U S A 1985
5



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.