Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
Times Cited: 413
Times Cited: 413
Times Cited
Times Co-cited
Similarity
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
50
Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
37
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
35
G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
35
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
30
Solution structure of a 2:1 quindoline-c-MYC G-quadruplex: insights into G-quadruplex-interactive small molecule drug design.
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
Jixun Dai, Megan Carver, Laurence H Hurley, Danzhou Yang. J Am Chem Soc 2011
27
Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.
Anh Tuân Phan, Yasha S Modi, Dinshaw J Patel. J Am Chem Soc 2004
Anh Tuân Phan, Yasha S Modi, Dinshaw J Patel. J Am Chem Soc 2004
26
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
24
Prevalence of quadruplexes in the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
23
DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
22
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
22
Quadruplex DNA: sequence, topology and structure.
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
20
Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J Patel. J Am Chem Soc 2007
Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J Patel. J Am Chem Soc 2007
18
G-quadruplexes in promoters throughout the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
17
c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.
Raveendra I Mathad, Emmanuel Hatzakis, Jixun Dai, Danzhou Yang. Nucleic Acids Res 2011
Raveendra I Mathad, Emmanuel Hatzakis, Jixun Dai, Danzhou Yang. Nucleic Acids Res 2011
17
Stability and kinetics of G-quadruplex structures.
Andrew N Lane, J Brad Chaires, Robert D Gray, John O Trent. Nucleic Acids Res 2008
Andrew N Lane, J Brad Chaires, Robert D Gray, John O Trent. Nucleic Acids Res 2008
17
The regulation and functions of DNA and RNA G-quadruplexes.
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
Dhaval Varshney, Jochen Spiegel, Katherine Zyner, David Tannahill, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2020
17
Circular dichroism and conformational polymorphism of DNA.
Jaroslav Kypr, Iva Kejnovská, Daniel Renciuk, Michaela Vorlícková. Nucleic Acids Res 2009
Jaroslav Kypr, Iva Kejnovská, Daniel Renciuk, Michaela Vorlícková. Nucleic Acids Res 2009
16
DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
16
The Structure and Function of DNA G-Quadruplexes.
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
Jochen Spiegel, Santosh Adhikari, Shankar Balasubramanian. Trends Chem 2020
16
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
15
15
The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.
Jeyaprakashnarayanan Seenisamy, Evonne M Rezler, Tiffanie J Powell, Denise Tye, Vijay Gokhale, Chandana Sharma Joshi, Adam Siddiqui-Jain, Laurence H Hurley. J Am Chem Soc 2004
Jeyaprakashnarayanan Seenisamy, Evonne M Rezler, Tiffanie J Powell, Denise Tye, Vijay Gokhale, Chandana Sharma Joshi, Adam Siddiqui-Jain, Laurence H Hurley. J Am Chem Soc 2004
15
Crystal structure of parallel quadruplexes from human telomeric DNA.
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
14
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
14
G-quadruplexes and helicases.
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
Oscar Mendoza, Anne Bourdoncle, Jean-Baptiste Boulé, Robert M Brosh, Jean-Louis Mergny. Nucleic Acids Res 2016
14
DNA tetraplex formation in the control region of c-myc.
T Simonsson, P Pecinka, M Kubista. Nucleic Acids Res 1998
T Simonsson, P Pecinka, M Kubista. Nucleic Acids Res 1998
14
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
13
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
13
Structure of the human telomere in K+ solution: an intramolecular (3 + 1) G-quadruplex scaffold.
Kim Ngoc Luu, Anh Tuân Phan, Vitaly Kuryavyi, Laurent Lacroix, Dinshaw J Patel. J Am Chem Soc 2006
Kim Ngoc Luu, Anh Tuân Phan, Vitaly Kuryavyi, Laurent Lacroix, Dinshaw J Patel. J Am Chem Soc 2006
13
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
13
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
Hong Xu, Marco Di Antonio, Steven McKinney, Veena Mathew, Brandon Ho, Nigel J O'Neil, Nancy Dos Santos, Jennifer Silvester, Vivien Wei, Jessica Garcia,[...]. Nat Commun 2017
13
Metal Cations in G-Quadruplex Folding and Stability.
Debmalya Bhattacharyya, Gayan Mirihana Arachchilage, Soumitra Basu. Front Chem 2016
Debmalya Bhattacharyya, Gayan Mirihana Arachchilage, Soumitra Basu. Front Chem 2016
13
Highly efficient G-quadruplex recognition by bisquinolinium compounds.
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
Anne De Cian, Elsa Delemos, Jean-Louis Mergny, Marie-Paule Teulade-Fichou, David Monchaud. J Am Chem Soc 2007
12
Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
12
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Y Wang, D J Patel. Structure 1993
Y Wang, D J Patel. Structure 1993
12
Thermodynamic stability and folding kinetics of the major G-quadruplex and its loop isomers formed in the nuclease hypersensitive element in the human c-Myc promoter: effect of loops and flanking segments on the stability of parallel-stranded intramolecular G-quadruplexes.
Emmanuel Hatzakis, Keika Okamoto, Danzhou Yang. Biochemistry 2010
Emmanuel Hatzakis, Keika Okamoto, Danzhou Yang. Biochemistry 2010
18
Highly prevalent putative quadruplex sequence motifs in human DNA.
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
12
Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3).
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
Wan Jun Chung, Brahim Heddi, Florian Hamon, Marie-Paule Teulade-Fichou, Anh Tuân Phan. Angew Chem Int Ed Engl 2014
12
Putative DNA quadruplex formation within the human c-kit oncogene.
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
11
Making sense of G-quadruplex and i-motif functions in oncogene promoters.
Tracy A Brooks, Samantha Kendrick, Laurence Hurley. FEBS J 2010
Tracy A Brooks, Samantha Kendrick, Laurence Hurley. FEBS J 2010
11
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
11
Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence.
Jixun Dai, Megan Carver, Chandanamali Punchihewa, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2007
Jixun Dai, Megan Carver, Chandanamali Punchihewa, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2007
11
Topological characterization of nucleic acid G-quadruplexes by UV absorption and circular dichroism.
Andreas Ioannis Karsisiotis, Nason Ma'ani Hessari, Ettore Novellino, Gian Piero Spada, Antonio Randazzo, Mateus Webba da Silva. Angew Chem Int Ed Engl 2011
Andreas Ioannis Karsisiotis, Nason Ma'ani Hessari, Ettore Novellino, Gian Piero Spada, Antonio Randazzo, Mateus Webba da Silva. Angew Chem Int Ed Engl 2011
11
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein.
Verónica González, Kexiao Guo, Laurence Hurley, Daekyu Sun. J Biol Chem 2009
Verónica González, Kexiao Guo, Laurence Hurley, Daekyu Sun. J Biol Chem 2009
11
Structure of the biologically relevant G-quadruplex in the c-MYC promoter.
Danzhou Yang, Laurence H Hurley. Nucleosides Nucleotides Nucleic Acids 2006
Danzhou Yang, Laurence H Hurley. Nucleosides Nucleotides Nucleic Acids 2006
11
Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex.
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
David R Calabrese, Xiang Chen, Elena C Leon, Snehal M Gaikwad, Zaw Phyo, William M Hewitt, Stephanie Alden, Thomas A Hilimire, Fahu He, Aleksandra M Michalowski,[...]. Nat Commun 2018
15
The major G-quadruplex formed in the human BCL-2 proximal promoter adopts a parallel structure with a 13-nt loop in K+ solution.
Prashansa Agrawal, Clement Lin, Raveendra I Mathad, Megan Carver, Danzhou Yang. J Am Chem Soc 2014
Prashansa Agrawal, Clement Lin, Raveendra I Mathad, Megan Carver, Danzhou Yang. J Am Chem Soc 2014
11
Targeting MYC Expression through G-Quadruplexes.
Tracy A Brooks, Laurence H Hurley. Genes Cancer 2010
Tracy A Brooks, Laurence H Hurley. Genes Cancer 2010
11
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