Beatriz Cubelos, Cecilio Giménez, Francisco Zafra. Cereb Cortex 2005
Times Cited: 223
Times Cited: 223
Times Cited
Times Co-cited
Similarity
Glycine transporters are differentially expressed among CNS cells.
F Zafra, C Aragón, L Olivares, N C Danbolt, C Giménez, J Storm-Mathisen. J Neurosci 1995
F Zafra, C Aragón, L Olivares, N C Danbolt, C Giménez, J Storm-Mathisen. J Neurosci 1995
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Glycine potentiates the NMDA response in cultured mouse brain neurons.
J W Johnson, P Ascher. Nature 1987
J W Johnson, P Ascher. Nature 1987
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Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
Jesús Gomeza, Swen Hülsmann, Koji Ohno, Volker Eulenburg, Katalin Szöke, Diethelm Richter, Heinrich Betz. Neuron 2003
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Glycine transporters: essential regulators of neurotransmission.
Volker Eulenburg, Wencke Armsen, Heinrich Betz, Jesús Gomeza. Trends Biochem Sci 2005
Volker Eulenburg, Wencke Armsen, Heinrich Betz, Jesús Gomeza. Trends Biochem Sci 2005
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Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS.
F Zafra, J Gomeza, L Olivares, C Aragón, C Giménez. Eur J Neurosci 1995
F Zafra, J Gomeza, L Olivares, C Aragón, C Giménez. Eur J Neurosci 1995
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Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain.
Robert J Harvey, Benjamin K Yee. Nat Rev Drug Discov 2013
Robert J Harvey, Benjamin K Yee. Nat Rev Drug Discov 2013
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Modulation of N-methyl-D-aspartate receptor function by glycine transport.
R Bergeron, T M Meyer, J T Coyle, R W Greene. Proc Natl Acad Sci U S A 1998
R Bergeron, T M Meyer, J T Coyle, R W Greene. Proc Natl Acad Sci U S A 1998
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Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
Jesús Gomeza, Koji Ohno, Swen Hülsmann, Wencke Armsen, Volker Eulenburg, Diethelm W Richter, Bodo Laube, Heinrich Betz. Neuron 2003
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Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists.
Thomas Papouin, Laurent Ladépêche, Jérôme Ruel, Silvia Sacchi, Marilyne Labasque, Marwa Hanini, Laurent Groc, Loredano Pollegioni, Jean-Pierre Mothet, Stéphane H R Oliet. Cell 2012
Thomas Papouin, Laurent Ladépêche, Jérôme Ruel, Silvia Sacchi, Marilyne Labasque, Marwa Hanini, Laurent Groc, Loredano Pollegioni, Jean-Pierre Mothet, Stéphane H R Oliet. Cell 2012
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Glycine binding primes NMDA receptor internalization.
Yi Nong, Yue-Qiao Huang, William Ju, Lorraine V Kalia, Gholamreza Ahmadian, Yu Tian Wang, Michael W Salter. Nature 2003
Yi Nong, Yue-Qiao Huang, William Ju, Lorraine V Kalia, Gholamreza Ahmadian, Yu Tian Wang, Michael W Salter. Nature 2003
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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.
Long Chen, Mark Muhlhauser, Charles R Yang. J Neurophysiol 2003
Long Chen, Mark Muhlhauser, Charles R Yang. J Neurophysiol 2003
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Neuronal and glial glycine transporters have different stoichiometries.
M J Roux, S Supplisson. Neuron 2000
M J Roux, S Supplisson. Neuron 2000
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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.
Marzia Martina, Yelena Gorfinkel, Samantha Halman, John A Lowe, Pranav Periyalwar, Christopher J Schmidt, Richard Bergeron. J Physiol 2004
Marzia Martina, Yelena Gorfinkel, Samantha Halman, John A Lowe, Pranav Periyalwar, Christopher J Schmidt, Richard Bergeron. J Physiol 2004
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Neurochemical, electrophysiological and pharmacological profiles of the selective inhibitor of the glycine transporter-1 SSR504734, a potential new type of antipsychotic.
Ronan Depoortère, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Annick Coste, Christophe Lanneau, Christophe Desvignes, Martine Poncelet, Michel Heaulme, Vincent Santucci, Michel Decobert,[...]. Neuropsychopharmacology 2005
Ronan Depoortère, Gihad Dargazanli, Genevieve Estenne-Bouhtou, Annick Coste, Christophe Lanneau, Christophe Desvignes, Martine Poncelet, Michel Heaulme, Vincent Santucci, Michel Decobert,[...]. Neuropsychopharmacology 2005
17
Spinal antiallodynia action of glycine transporter inhibitors in neuropathic pain models in mice.
Katsuya Morita, Naoyo Motoyama, Tomoya Kitayama, Norimitsu Morioka, Koki Kifune, Toshihiro Dohi. J Pharmacol Exp Ther 2008
Katsuya Morita, Naoyo Motoyama, Tomoya Kitayama, Norimitsu Morioka, Koki Kifune, Toshihiro Dohi. J Pharmacol Exp Ther 2008
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Glycine transporters: essential regulators of synaptic transmission.
H Betz, J Gomeza, W Armsen, P Scholze, V Eulenburg. Biochem Soc Trans 2006
H Betz, J Gomeza, W Armsen, P Scholze, V Eulenburg. Biochem Soc Trans 2006
16
Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors.
K E Smith, L A Borden, P R Hartig, T Branchek, R L Weinshank. Neuron 1992
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Glycine reuptake inhibitor RG1678: a pharmacologic characterization of an investigational agent for the treatment of schizophrenia.
Daniela Alberati, Jean-Luc Moreau, Judith Lengyel, Nicole Hauser, Roland Mory, Edilio Borroni, Emmanuel Pinard, Frederic Knoflach, Götz Schlotterbeck, Dominik Hainzl,[...]. Neuropharmacology 2012
Daniela Alberati, Jean-Luc Moreau, Judith Lengyel, Nicole Hauser, Roland Mory, Edilio Borroni, Emmanuel Pinard, Frederic Knoflach, Götz Schlotterbeck, Dominik Hainzl,[...]. Neuropharmacology 2012
17
Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile.
Benjamin K Yee, Ela Balic, Philipp Singer, Cornelia Schwerdel, Thomas Grampp, Laetitia Gabernet, Irene Knuesel, Dietmar Benke, Joram Feldon, Hanns Mohler,[...]. J Neurosci 2006
Benjamin K Yee, Ela Balic, Philipp Singer, Cornelia Schwerdel, Thomas Grampp, Laetitia Gabernet, Irene Knuesel, Dietmar Benke, Joram Feldon, Hanns Mohler,[...]. J Neurosci 2006
16
ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter.
B N Atkinson, S C Bell, M De Vivo, L R Kowalski, S M Lechner, V I Ognyanov, C S Tham, C Tsai, J Jia, D Ashton,[...]. Mol Pharmacol 2001
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16
Gene knockout of glycine transporter 1: characterization of the behavioral phenotype.
Guochuan Tsai, Rebecca J Ralph-Williams, Marzia Martina, Richard Bergeron, Joanne Berger-Sweeney, Kevin S Dunham, Zhichun Jiang, S Barak Caine, Joseph T Coyle. Proc Natl Acad Sci U S A 2004
Guochuan Tsai, Rebecca J Ralph-Williams, Marzia Martina, Richard Bergeron, Joanne Berger-Sweeney, Kevin S Dunham, Zhichun Jiang, S Barak Caine, Joseph T Coyle. Proc Natl Acad Sci U S A 2004
15
Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene.
B Borowsky, E Mezey, B J Hoffman. Neuron 1993
B Borowsky, E Mezey, B J Hoffman. Neuron 1993
15
Glial glycine transporter 1 function is essential for early postnatal survival but dispensable in adult mice.
Volker Eulenburg, Marina Retiounskaia, Theofilos Papadopoulos, Jesús Gomeza, Heinrich Betz. Glia 2010
Volker Eulenburg, Marina Retiounskaia, Theofilos Papadopoulos, Jesús Gomeza, Heinrich Betz. Glia 2010
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Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain.
F Jursky, N Nelson. J Neurochem 1996
F Jursky, N Nelson. J Neurochem 1996
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Functional 'glial' GLYT1 glycine transporters expressed in neurons.
Luca Raiteri, Maurizio Raiteri. J Neurochem 2010
Luca Raiteri, Maurizio Raiteri. J Neurochem 2010
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D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.
J P Mothet, A T Parent, H Wolosker, R O Brady, D J Linden, C D Ferris, M A Rogawski, S H Snyder. Proc Natl Acad Sci U S A 2000
J P Mothet, A T Parent, H Wolosker, R O Brady, D J Linden, C D Ferris, M A Rogawski, S H Snyder. Proc Natl Acad Sci U S A 2000
13
Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia.
Emmanuel Pinard, Alexander Alanine, Daniela Alberati, Markus Bender, Edilio Borroni, Patrick Bourdeaux, Virginie Brom, Serge Burner, Holger Fischer, Dominik Hainzl,[...]. J Med Chem 2010
Emmanuel Pinard, Alexander Alanine, Daniela Alberati, Markus Bender, Edilio Borroni, Patrick Bourdeaux, Virginie Brom, Serge Burner, Holger Fischer, Dominik Hainzl,[...]. J Med Chem 2010
13
Inhibitors of GlyT1 affect glycine transport via discrete binding sites.
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
Mario Mezler, Wilfried Hornberger, Reinhold Mueller, Martin Schmidt, Willi Amberg, Wilfried Braje, Michael Ochse, Hans Schoemaker, Berthold Behl. Mol Pharmacol 2008
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Neurochemical and behavioral profiling of the selective GlyT1 inhibitors ALX5407 and LY2365109 indicate a preferential action in caudal vs. cortical brain areas.
Kenneth W Perry, Julie F Falcone, Matthew J Fell, John W Ryder, Hong Yu, Patrick L Love, Jason Katner, Kimberly D Gordon, Mark R Wade, Teresa Man,[...]. Neuropharmacology 2008
Kenneth W Perry, Julie F Falcone, Matthew J Fell, John W Ryder, Hong Yu, Patrick L Love, Jason Katner, Kimberly D Gordon, Mark R Wade, Teresa Man,[...]. Neuropharmacology 2008
18
Why glycine transporters have different stoichiometries.
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
Stéphane Supplisson, Michel J Roux. FEBS Lett 2002
14
The scaffolding protein PSD-95 interacts with the glycine transporter GLYT1 and impairs its internalization.
Beatriz Cubelos, Inmaculada M González-González, Cecilio Giménez, Francisco Zafra. J Neurochem 2005
Beatriz Cubelos, Inmaculada M González-González, Cecilio Giménez, Francisco Zafra. J Neurochem 2005
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The synthesis and preclinical evaluation in rhesus monkey of [¹⁸F]MK-6577 and [¹¹C]CMPyPB glycine transporter 1 positron emission tomography radiotracers.
Terence G Hamill, Waisi Eng, Andrew Jennings, Richard Lewis, Steven Thomas, Suzanne Wood, Leslie Street, David Wisnoski, Scott Wolkenberg, Craig Lindsley,[...]. Synapse 2011
Terence G Hamill, Waisi Eng, Andrew Jennings, Richard Lewis, Steven Thomas, Suzanne Wood, Leslie Street, David Wisnoski, Scott Wolkenberg, Craig Lindsley,[...]. Synapse 2011
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Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications.
W Danysz, C G Parsons. Pharmacol Rev 1998
W Danysz, C G Parsons. Pharmacol Rev 1998
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Glycine transporter type-1 and its inhibitors.
L G Harsing, Z Juranyi, I Gacsalyi, P Tapolcsanyi, A Czompa, P Matyus. Curr Med Chem 2006
L G Harsing, Z Juranyi, I Gacsalyi, P Tapolcsanyi, A Czompa, P Matyus. Curr Med Chem 2006
21
The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.
Gene G Kinney, Cyrille Sur, Maryann Burno, Pierre J Mallorga, Jacinta B Williams, David J Figueroa, Marion Wittmann, Wei Lemaire, P Jeffrey Conn. J Neurosci 2003
Gene G Kinney, Cyrille Sur, Maryann Burno, Pierre J Mallorga, Jacinta B Williams, David J Figueroa, Marion Wittmann, Wei Lemaire, P Jeffrey Conn. J Neurosci 2003
12
Glutamate receptor ion channels: structure, regulation, and function.
Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
Stephen F Traynelis, Lonnie P Wollmuth, Chris J McBain, Frank S Menniti, Katie M Vance, Kevin K Ogden, Kasper B Hansen, Hongjie Yuan, Scott J Myers, Ray Dingledine. Pharmacol Rev 2010
12
Glycine transporter inhibitors as a novel drug discovery strategy for neuropathic pain.
Toshihiro Dohi, Katsuya Morita, Tomoya Kitayama, Naoyo Motoyama, Norimitsu Morioka. Pharmacol Ther 2009
Toshihiro Dohi, Katsuya Morita, Tomoya Kitayama, Naoyo Motoyama, Norimitsu Morioka. Pharmacol Ther 2009
15
Morphologically identified glycinergic synapses in the hippocampus.
Lydia Danglot, Philippe Rostaing, Antoine Triller, Alain Bessis. Mol Cell Neurosci 2004
Lydia Danglot, Philippe Rostaing, Antoine Triller, Alain Bessis. Mol Cell Neurosci 2004
16
Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion.
Carmen Aragón, Beatriz López-Corcuera. Trends Pharmacol Sci 2005
Carmen Aragón, Beatriz López-Corcuera. Trends Pharmacol Sci 2005
13
Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats.
Franziska Barthel, Andrea Urban, Lukas Schlösser, Volker Eulenburg, Robert Werdehausen, Timo Brandenburger, Carmen Aragon, Inge Bauer, Henning Hermanns. Anesthesiology 2014
Franziska Barthel, Andrea Urban, Lukas Schlösser, Volker Eulenburg, Robert Werdehausen, Timo Brandenburger, Carmen Aragon, Inge Bauer, Henning Hermanns. Anesthesiology 2014
46
Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice.
Marzia Martina, Marie-Eve B-Turcotte, Samantha Halman, Guochuan Tsai, Mario Tiberi, Joseph T Coyle, Richard Bergeron. J Physiol 2005
Marzia Martina, Marie-Eve B-Turcotte, Samantha Halman, Guochuan Tsai, Mario Tiberi, Joseph T Coyle, Richard Bergeron. J Physiol 2005
25
Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia.
Guochuan Tsai, Hsien-Yuan Lane, Pinchen Yang, Mian-Yoon Chong, Nicholas Lange. Biol Psychiatry 2004
Guochuan Tsai, Hsien-Yuan Lane, Pinchen Yang, Mian-Yoon Chong, Nicholas Lange. Biol Psychiatry 2004
11
Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
H J Herdon, F M Godfrey, A M Brown, S Coulton, J R Evans, W J Cairns. Neuropharmacology 2001
14
The glycine transporter GlyT2 controls the dynamics of synaptic vesicle refilling in inhibitory spinal cord neurons.
France Rousseau, Karin R Aubrey, Stéphane Supplisson. J Neurosci 2008
France Rousseau, Karin R Aubrey, Stéphane Supplisson. J Neurosci 2008
15
The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study.
Laszlo G Harsing, Istvan Gacsalyi, Geza Szabo, Eva Schmidt, Nora Sziray, Claude Sebban, Brigitte Tesolin-Decros, Peter Matyus, Andras Egyed, Michael Spedding,[...]. Pharmacol Biochem Behav 2003
Laszlo G Harsing, Istvan Gacsalyi, Geza Szabo, Eva Schmidt, Nora Sziray, Claude Sebban, Brigitte Tesolin-Decros, Peter Matyus, Andras Egyed, Michael Spedding,[...]. Pharmacol Biochem Behav 2003
12
Mutations in the gene encoding GlyT2 (SLC6A5) define a presynaptic component of human startle disease.
Mark I Rees, Kirsten Harvey, Brian R Pearce, Seo-Kyung Chung, Ian C Duguid, Philip Thomas, Sarah Beatty, Gail E Graham, Linlea Armstrong, Rita Shiang,[...]. Nat Genet 2006
Mark I Rees, Kirsten Harvey, Brian R Pearce, Seo-Kyung Chung, Ian C Duguid, Philip Thomas, Sarah Beatty, Gail E Graham, Linlea Armstrong, Rita Shiang,[...]. Nat Genet 2006
11
Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study.
Daniel Umbricht, Daniela Alberati, Meret Martin-Facklam, Edilio Borroni, Eriene A Youssef, Michael Ostland, Tanya L Wallace, Frédéric Knoflach, Ernest Dorflinger, Joseph G Wettstein,[...]. JAMA Psychiatry 2014
Daniel Umbricht, Daniela Alberati, Meret Martin-Facklam, Edilio Borroni, Eriene A Youssef, Michael Ostland, Tanya L Wallace, Frédéric Knoflach, Ernest Dorflinger, Joseph G Wettstein,[...]. JAMA Psychiatry 2014
11
Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes.
S Supplisson, C Bergman. J Neurosci 1997
S Supplisson, C Bergman. J Neurosci 1997
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Recent advances in the phencyclidine model of schizophrenia.
D C Javitt, S R Zukin. Am J Psychiatry 1991
D C Javitt, S R Zukin. Am J Psychiatry 1991
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.