M G Butler, M J Dasouki, X-P Zhou, Z Talebizadeh, M Brown, T N Takahashi, J H Miles, C H Wang, R Stratton, R Pilarski, C Eng. J Med Genet 2005
Times Cited: 518
Times Cited: 518
Times Cited
Times Co-cited
Similarity
Pten regulates neuronal arborization and social interaction in mice.
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
Chang-Hyuk Kwon, Bryan W Luikart, Craig M Powell, Jing Zhou, Sharon A Matheny, Wei Zhang, Yanjiao Li, Suzanne J Baker, Luis F Parada. Neuron 2006
27
Molecular and phenotypic abnormalities in individuals with germline heterozygous PTEN mutations and autism.
T W Frazier, R Embacher, A K Tilot, K Koenig, J Mester, C Eng. Mol Psychiatry 2015
T W Frazier, R Embacher, A K Tilot, K Koenig, J Mester, C Eng. Mol Psychiatry 2015
28
Mutation screening of the PTEN gene in patients with autism spectrum disorders and macrocephaly.
Joseph D Buxbaum, Guiqing Cai, Pauline Chaste, Gudrun Nygren, Juliet Goldsmith, Jennifer Reichert, Henrik Anckarsäter, Maria Rastam, Christopher J Smith, Jeremy M Silverman,[...]. Am J Med Genet B Neuropsychiatr Genet 2007
Joseph D Buxbaum, Guiqing Cai, Pauline Chaste, Gudrun Nygren, Juliet Goldsmith, Jennifer Reichert, Henrik Anckarsäter, Maria Rastam, Christopher J Smith, Jeremy M Silverman,[...]. Am J Med Genet B Neuropsychiatr Genet 2007
26
The prevalence of PTEN mutations in a clinical pediatric cohort with autism spectrum disorders, developmental delay, and macrocephaly.
Elizabeth A Varga, Matthew Pastore, Thomas Prior, Gail E Herman, Kim L McBride. Genet Med 2009
Elizabeth A Varga, Matthew Pastore, Thomas Prior, Gail E Herman, Kim L McBride. Genet Med 2009
24
Confirmation study of PTEN mutations among individuals with autism or developmental delays/mental retardation and macrocephaly.
Kim L McBride, Elizabeth A Varga, Matthew T Pastore, Thomas W Prior, Kandamurugu Manickam, Joan F Atkin, Gail E Herman. Autism Res 2010
Kim L McBride, Elizabeth A Varga, Matthew T Pastore, Thomas W Prior, Kandamurugu Manickam, Joan F Atkin, Gail E Herman. Autism Res 2010
21
A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands.
Min-Han Tan, Jessica Mester, Charissa Peterson, Yiran Yang, Jin-Lian Chen, Lisa A Rybicki, Kresimira Milas, Holly Pederson, Berna Remzi, Mohammed S Orloff,[...]. Am J Hum Genet 2011
Min-Han Tan, Jessica Mester, Charissa Peterson, Yiran Yang, Jin-Lian Chen, Lisa A Rybicki, Kresimira Milas, Holly Pederson, Berna Remzi, Mohammed S Orloff,[...]. Am J Hum Genet 2011
19
Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
Jing Zhou, Jacqueline Blundell, Shiori Ogawa, Chang-Hyuk Kwon, Wei Zhang, Christopher Sinton, Craig M Powell, Luis F Parada. J Neurosci 2009
Jing Zhou, Jacqueline Blundell, Shiori Ogawa, Chang-Hyuk Kwon, Wei Zhang, Christopher Sinton, Craig M Powell, Luis F Parada. J Neurosci 2009
18
Lifetime cancer risks in individuals with germline PTEN mutations.
Min-Han Tan, Jessica L Mester, Joanne Ngeow, Lisa A Rybicki, Mohammed S Orloff, Charis Eng. Clin Cancer Res 2012
Min-Han Tan, Jessica L Mester, Joanne Ngeow, Lisa A Rybicki, Mohammed S Orloff, Charis Eng. Clin Cancer Res 2012
17
Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production.
Amanda K Tilot, Mary K Gaugler, Qi Yu, Todd Romigh, Wanfeng Yu, Robert H Miller, Thomas W Frazier, Charis Eng. Hum Mol Genet 2014
Amanda K Tilot, Mary K Gaugler, Qi Yu, Todd Romigh, Wanfeng Yu, Robert H Miller, Thomas W Frazier, Charis Eng. Hum Mol Genet 2014
39
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome.
D Liaw, D J Marsh, J Li, P L Dahia, S I Wang, Z Zheng, S Bose, K M Call, H C Tsou, M Peacocke,[...]. Nat Genet 1997
D Liaw, D J Marsh, J Li, P L Dahia, S I Wang, Z Zheng, S Bose, K M Call, H C Tsou, M Peacocke,[...]. Nat Genet 1997
14
Pten haploinsufficient mice show broad brain overgrowth but selective impairments in autism-relevant behavioral tests.
Amy E Clipperton-Allen, Damon T Page. Hum Mol Genet 2014
Amy E Clipperton-Allen, Damon T Page. Hum Mol Genet 2014
20
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.
T Maehama, J E Dixon. J Biol Chem 1998
T Maehama, J E Dixon. J Biol Chem 1998
14
PTEN mutation in a family with Cowden syndrome and autism.
A Goffin, L H Hoefsloot, E Bosgoed, A Swillen, J P Fryns. Am J Med Genet 2001
A Goffin, L H Hoefsloot, E Bosgoed, A Swillen, J P Fryns. Am J Med Genet 2001
14
Increasing knowledge of PTEN germline mutations: Two additional patients with autism and macrocephaly.
Gail E Herman, Eric Butter, Benedicta Enrile, Matthew Pastore, Thomas W Prior, Annemarie Sommer. Am J Med Genet A 2007
Gail E Herman, Eric Butter, Benedicta Enrile, Matthew Pastore, Thomas W Prior, Annemarie Sommer. Am J Med Genet A 2007
14
Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder.
Amanda K Tilot, Thomas W Frazier, Charis Eng. Neurotherapeutics 2015
Amanda K Tilot, Thomas W Frazier, Charis Eng. Neurotherapeutics 2015
31
A retrospective chart review of the features of PTEN hamartoma tumour syndrome in children.
Emily Hansen-Kiss, Sarah Beinkampen, Brent Adler, Thomas Frazier, Thomas Prior, Steven Erdman, Charis Eng, Gail Herman. J Med Genet 2017
Emily Hansen-Kiss, Sarah Beinkampen, Brent Adler, Thomas Frazier, Thomas Prior, Steven Erdman, Charis Eng, Gail Herman. J Med Genet 2017
28
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders.
Brian J O'Roak, Laura Vives, Wenqing Fu, Jarrett D Egertson, Ian B Stanaway, Ian G Phelps, Gemma Carvill, Akash Kumar, Choli Lee, Katy Ankenman,[...]. Science 2012
Brian J O'Roak, Laura Vives, Wenqing Fu, Jarrett D Egertson, Ian B Stanaway, Ian G Phelps, Gemma Carvill, Akash Kumar, Choli Lee, Katy Ankenman,[...]. Science 2012
14
Macrocephaly as a clinical indicator of genetic subtypes in autism.
Steven Klein, Pantea Sharifi-Hannauer, Julian A Martinez-Agosto. Autism Res 2013
Steven Klein, Pantea Sharifi-Hannauer, Julian A Martinez-Agosto. Autism Res 2013
27
Synaptic, transcriptional and chromatin genes disrupted in autism.
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
Silvia De Rubeis, Xin He, Arthur P Goldberg, Christopher S Poultney, Kaitlin Samocha, A Erucment Cicek, Yan Kou, Li Liu, Menachem Fromer, Susan Walker,[...]. Nature 2014
13
Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease.
C H Kwon, X Zhu, J Zhang, L L Knoop, R Tharp, R J Smeyne, C G Eberhart, P C Burger, S J Baker. Nat Genet 2001
C H Kwon, X Zhu, J Zhang, L L Knoop, R Tharp, R J Smeyne, C G Eberhart, P C Burger, S J Baker. Nat Genet 2001
12
Most genetic risk for autism resides with common variation.
Trent Gaugler, Lambertus Klei, Stephan J Sanders, Corneliu A Bodea, Arthur P Goldberg, Ann B Lee, Milind Mahajan, Dina Manaa, Yudi Pawitan, Jennifer Reichert,[...]. Nat Genet 2014
Trent Gaugler, Lambertus Klei, Stephan J Sanders, Corneliu A Bodea, Arthur P Goldberg, Ann B Lee, Milind Mahajan, Dina Manaa, Yudi Pawitan, Jennifer Reichert,[...]. Nat Genet 2014
12
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation.
D J Marsh, V Coulon, K L Lunetta, P Rocca-Serra, P L Dahia, Z Zheng, D Liaw, S Caron, B Duboué, A Y Lin,[...]. Hum Mol Genet 1998
D J Marsh, V Coulon, K L Lunetta, P Rocca-Serra, P L Dahia, Z Zheng, D Liaw, S Caron, B Duboué, A Y Lin,[...]. Hum Mol Genet 1998
12
Cerebral organoids model human brain development and microcephaly.
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
Madeline A Lancaster, Magdalena Renner, Carol-Anne Martin, Daniel Wenzel, Louise S Bicknell, Matthew E Hurles, Tessa Homfray, Josef M Penninger, Andrew P Jackson, Juergen A Knoblich. Nature 2013
12
A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships.
Taylor L Mighell, Sara Evans-Dutson, Brian J O'Roak. Am J Hum Genet 2018
Taylor L Mighell, Sara Evans-Dutson, Brian J O'Roak. Am J Hum Genet 2018
17
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism.
F Kyle Satterstrom, Jack A Kosmicki, Jiebiao Wang, Michael S Breen, Silvia De Rubeis, Joon-Yong An, Minshi Peng, Ryan Collins, Jakob Grove, Lambertus Klei,[...]. Cell 2020
F Kyle Satterstrom, Jack A Kosmicki, Jiebiao Wang, Michael S Breen, Silvia De Rubeis, Joon-Yong An, Minshi Peng, Ryan Collins, Jakob Grove, Lambertus Klei,[...]. Cell 2020
12
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome.
D J Marsh, J B Kum, K L Lunetta, M J Bennett, R J Gorlin, S F Ahmed, J Bodurtha, C Crowe, M A Curtis, M Dasouki,[...]. Hum Mol Genet 1999
D J Marsh, J B Kum, K L Lunetta, M J Bennett, R J Gorlin, S F Ahmed, J Bodurtha, C Crowe, M A Curtis, M Dasouki,[...]. Hum Mol Genet 1999
11
Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes.
Laura Spinelli, Fiona M Black, Jonathan N Berg, Britta J Eickholt, Nicholas R Leslie. J Med Genet 2015
Laura Spinelli, Fiona M Black, Jonathan N Berg, Britta J Eickholt, Nicholas R Leslie. J Med Genet 2015
16
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.
J Li, C Yen, D Liaw, K Podsypanina, S Bose, S I Wang, J Puc, C Miliaresis, L Rodgers, R McCombie,[...]. Science 1997
J Li, C Yen, D Liaw, K Podsypanina, S Bose, S I Wang, J Puc, C Miliaresis, L Rodgers, R McCombie,[...]. Science 1997
11
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction.
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
João Peça, Cátia Feliciano, Jonathan T Ting, Wenting Wang, Michael F Wells, Talaignair N Venkatraman, Christopher D Lascola, Zhanyan Fu, Guoping Feng. Nature 2011
11
Novel PTEN mutations in neurodevelopmental disorders and macrocephaly.
A Orrico, L Galli, S Buoni, A Orsi, G Vonella, V Sorrentino. Clin Genet 2009
A Orrico, L Galli, S Buoni, A Orsi, G Vonella, V Sorrentino. Clin Genet 2009
13
Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder.
A K Tilot, G Bebek, F Niazi, J B Altemus, T Romigh, T W Frazier, C Eng. Mol Psychiatry 2016
A K Tilot, G Bebek, F Niazi, J B Altemus, T Romigh, T W Frazier, C Eng. Mol Psychiatry 2016
29
Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism.
Kit San Yeung, Winnie Wan Yee Tso, Janice Jing Kun Ip, Christopher Chun Yu Mak, Gordon Ka Chun Leung, Mandy Ho Yin Tsang, Dingge Ying, Steven Lim Cho Pei, So Lun Lee, Wanling Yang,[...]. Mol Autism 2017
Kit San Yeung, Winnie Wan Yee Tso, Janice Jing Kun Ip, Christopher Chun Yu Mak, Gordon Ka Chun Leung, Mandy Ho Yin Tsang, Dingge Ying, Steven Lim Cho Pei, So Lun Lee, Wanling Yang,[...]. Mol Autism 2017
21
The contribution of de novo coding mutations to autism spectrum disorder.
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
Ivan Iossifov, Brian J O'Roak, Stephan J Sanders, Michael Ronemus, Niklas Krumm, Dan Levy, Holly A Stessman, Kali T Witherspoon, Laura Vives, Karynne E Patterson,[...]. Nature 2014
11
PTEN-opathies: from biological insights to evidence-based precision medicine.
Lamis Yehia, Joanne Ngeow, Charis Eng. J Clin Invest 2019
Lamis Yehia, Joanne Ngeow, Charis Eng. J Clin Invest 2019
15
Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice.
Dario Cupolillo, Eriola Hoxha, Alessio Faralli, Annarita De Luca, Ferdinando Rossi, Filippo Tempia, Daniela Carulli. Neuropsychopharmacology 2016
Dario Cupolillo, Eriola Hoxha, Alessio Faralli, Annarita De Luca, Ferdinando Rossi, Filippo Tempia, Daniela Carulli. Neuropsychopharmacology 2016
15
Pten Mutations Alter Brain Growth Trajectory and Allocation of Cell Types through Elevated β-Catenin Signaling.
Youjun Chen, Wen-Chin Huang, Julien Séjourné, Amy E Clipperton-Allen, Damon T Page. J Neurosci 2015
Youjun Chen, Wen-Chin Huang, Julien Séjourné, Amy E Clipperton-Allen, Damon T Page. J Neurosci 2015
14
Haploinsufficiency for Pten and Serotonin transporter cooperatively influences brain size and social behavior.
Damon T Page, Orsolya J Kuti, Chrysa Prestia, Mriganka Sur. Proc Natl Acad Sci U S A 2009
Damon T Page, Orsolya J Kuti, Chrysa Prestia, Mriganka Sur. Proc Natl Acad Sci U S A 2009
10
Characteristic brain magnetic resonance imaging pattern in patients with macrocephaly and PTEN mutations.
Adeline Vanderver, Davide Tonduti, Ilana Kahn, Johanna Schmidt, Livija Medne, Jodie Vento, Kimberly A Chapman, Brendan Lanpher, Phillip Pearl, Andrea Gropman,[...]. Am J Med Genet A 2014
Adeline Vanderver, Davide Tonduti, Ilana Kahn, Johanna Schmidt, Livija Medne, Jodie Vento, Kimberly A Chapman, Brendan Lanpher, Phillip Pearl, Andrea Gropman,[...]. Am J Med Genet A 2014
18
Disruptive CHD8 mutations define a subtype of autism early in development.
Raphael Bernier, Christelle Golzio, Bo Xiong, Holly A Stessman, Bradley P Coe, Osnat Penn, Kali Witherspoon, Jennifer Gerdts, Carl Baker, Anneke T Vulto-van Silfhout,[...]. Cell 2014
Raphael Bernier, Christelle Golzio, Bo Xiong, Holly A Stessman, Bradley P Coe, Osnat Penn, Kali Witherspoon, Jennifer Gerdts, Carl Baker, Anneke T Vulto-van Silfhout,[...]. Cell 2014
10
Cognitive characteristics of PTEN hamartoma tumor syndromes.
Robyn M Busch, Jessica S Chapin, Jessica Mester, Lisa Ferguson, Jennifer S Haut, Thomas W Frazier, Charis Eng. Genet Med 2013
Robyn M Busch, Jessica S Chapin, Jessica Mester, Lisa Ferguson, Jennifer S Haut, Thomas W Frazier, Charis Eng. Genet Med 2013
32
Biochemical screening and PTEN mutation analysis in individuals with autism spectrum disorders and macrocephaly.
Judith A Hobert, Rebecca Embacher, Jessica L Mester, Thomas W Frazier, Charis Eng. Eur J Hum Genet 2014
Judith A Hobert, Rebecca Embacher, Jessica L Mester, Thomas W Frazier, Charis Eng. Eur J Hum Genet 2014
17
Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.
Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parada. J Neurosci 2012
Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parada. J Neurosci 2012
10
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease.
S A Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, M S Tsao, P Shannon, B Bolon, G O Ivy,[...]. Nat Genet 2001
S A Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, M S Tsao, P Shannon, B Bolon, G O Ivy,[...]. Nat Genet 2001
9
A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromes.
Isabel Rodríguez-Escudero, María D Oliver, Amparo Andrés-Pons, María Molina, Víctor J Cid, Rafael Pulido. Hum Mol Genet 2011
Isabel Rodríguez-Escudero, María D Oliver, Amparo Andrés-Pons, María Molina, Víctor J Cid, Rafael Pulido. Hum Mol Genet 2011
9
Germline mutations in PTEN are present in Bannayan-Zonana syndrome.
D J Marsh, P L Dahia, Z Zheng, D Liaw, R Parsons, R J Gorlin, C Eng. Nat Genet 1997
D J Marsh, P L Dahia, Z Zheng, D Liaw, R Parsons, R J Gorlin, C Eng. Nat Genet 1997
9
Broad spectrum of neuropsychiatric phenotypes associated with white matter disease in PTEN hamartoma tumor syndrome.
Tugce B Balci, Jorge Davila, Denice Lewis, Addo Boafo, Erick Sell, Julie Richer, Sarah M Nikkel, Christine M Armour, Eva Tomiak, Matthew A Lines,[...]. Am J Med Genet B Neuropsychiatr Genet 2018
Tugce B Balci, Jorge Davila, Denice Lewis, Addo Boafo, Erick Sell, Julie Richer, Sarah M Nikkel, Christine M Armour, Eva Tomiak, Matthew A Lines,[...]. Am J Med Genet B Neuropsychiatr Genet 2018
45
Assembly of functionally integrated human forebrain spheroids.
Fikri Birey, Jimena Andersen, Christopher D Makinson, Saiful Islam, Wu Wei, Nina Huber, H Christina Fan, Kimberly R Cordes Metzler, Georgia Panagiotakos, Nicholas Thom,[...]. Nature 2017
Fikri Birey, Jimena Andersen, Christopher D Makinson, Saiful Islam, Wu Wei, Nina Huber, H Christina Fan, Kimberly R Cordes Metzler, Georgia Panagiotakos, Nicholas Thom,[...]. Nature 2017
9
Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model.
Jessica L Mester, Amanda K Tilot, Lisa A Rybicki, Thomas W Frazier, Charis Eng. Eur J Hum Genet 2011
Jessica L Mester, Amanda K Tilot, Lisa A Rybicki, Thomas W Frazier, Charis Eng. Eur J Hum Genet 2011
13
Clinical spectrum of PTEN mutation in pediatric patients. A bicenter experience.
Claudia Ciaccio, Veronica Saletti, Stefano D'Arrigo, Silvia Esposito, Enrico Alfei, Isabella Moroni, Davide Tonduti, Luisa Chiapparini, Chiara Pantaleoni, Donatella Milani. Eur J Med Genet 2019
Claudia Ciaccio, Veronica Saletti, Stefano D'Arrigo, Silvia Esposito, Enrico Alfei, Isabella Moroni, Davide Tonduti, Luisa Chiapparini, Chiara Pantaleoni, Donatella Milani. Eur J Med Genet 2019
37
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.