A citation-based method for searching scientific literature

Vassilis G Gorgoulis, Leandros-Vassilios F Vassiliou, Panagiotis Karakaidos, Panayotis Zacharatos, Athanassios Kotsinas, Triantafillos Liloglou, Monica Venere, Richard A Ditullio, Nikolaos G Kastrinakis, Brynn Levy, Dimitris Kletsas, Akihiro Yoneta, Meenhard Herlyn, Christos Kittas, Thanos D Halazonetis. Nature 2005
Times Cited: 1578







List of co-cited articles
1044 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Jirina Bartkova, Zuzana Horejsí, Karen Koed, Alwin Krämer, Frederic Tort, Karsten Zieger, Per Guldberg, Maxwell Sehested, Jahn M Nesland, Claudia Lukas,[...]. Nature 2005
64

An oncogene-induced DNA damage model for cancer development.
Thanos D Halazonetis, Vassilis G Gorgoulis, Jiri Bartek. Science 2008
26

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
21

Genomic instability--an evolving hallmark of cancer.
Simona Negrini, Vassilis G Gorgoulis, Thanos D Halazonetis. Nat Rev Mol Cell Biol 2010
20

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Jirina Bartkova, Nousin Rezaei, Michalis Liontos, Panagiotis Karakaidos, Dimitris Kletsas, Natalia Issaeva, Leandros-Vassilios F Vassiliou, Evangelos Kolettas, Katerina Niforou, Vassilis C Zoumpourlis,[...]. Nature 2006
18

Causes and consequences of replication stress.
Michelle K Zeman, Karlene A Cimprich. Nat Cell Biol 2014
17

The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
16

DNA replication stress as a hallmark of cancer.
Morgane Macheret, Thanos D Halazonetis. Annu Rev Pathol 2015
372
15

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.
Raffaella Di Micco, Marzia Fumagalli, Angelo Cicalese, Sara Piccinin, Patrizia Gasparini, Chiara Luise, Catherine Schurra, Massimiliano Garre', Paolo Giovanni Nuciforo, Aaron Bensimon,[...]. Nature 2006
14


Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy.
Hannah Farmer, Nuala McCabe, Christopher J Lord, Andrew N J Tutt, Damian A Johnson, Tobias B Richardson, Manuela Santarosa, Krystyna J Dillon, Ian Hickson, Charlotte Knights,[...]. Nature 2005
9

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress.
Claudia Lukas, Velibor Savic, Simon Bekker-Jensen, Carsten Doil, Beate Neumann, Ronni Sølvhøj Pedersen, Merete Grøfte, Kok Lung Chan, Ian David Hickson, Jiri Bartek,[...]. Nat Cell Biol 2011
461
9

Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.
Panagiotis Kotsantis, Eva Petermann, Simon J Boulton. Cancer Discov 2018
140
9

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
E P Rogakou, D R Pilch, A H Orr, V S Ivanova, W M Bonner. J Biol Chem 1998
9

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
Shuhei Matsuoka, Bryan A Ballif, Agata Smogorzewska, E Robert McDonald, Kristen E Hurov, Ji Luo, Corey E Bakalarski, Zhenming Zhao, Nicole Solimini, Yaniv Lerenthal,[...]. Science 2007
9

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.
Helen E Bryant, Niklas Schultz, Huw D Thomas, Kayan M Parker, Dan Flower, Elena Lopez, Suzanne Kyle, Mark Meuth, Nicola J Curtin, Thomas Helleday. Nature 2005
8


The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
7

Nucleotide deficiency promotes genomic instability in early stages of cancer development.
Assaf C Bester, Maayan Roniger, Yifat S Oren, Michael M Im, Dan Sarni, Malka Chaoat, Aaron Bensimon, Gideon Zamir, Donna S Shewach, Batsheva Kerem. Cell 2011
541
7

Chromosome fragile sites.
Sandra G Durkin, Thomas W Glover. Annu Rev Genet 2007
507
7

Replication stress and cancer.
Hélène Gaillard, Tatiana García-Muse, Andrés Aguilera. Nat Rev Cancer 2015
458
7

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors.
Matilde Murga, Stefano Campaner, Andres J Lopez-Contreras, Luis I Toledo, Rebeca Soria, Maria F Montaña, Luana D' Artista, Thomas Schleker, Carmen Guerra, Elena Garcia,[...]. Nat Struct Mol Biol 2011
257
7

The essential kinase ATR: ensuring faithful duplication of a challenging genome.
Joshua C Saldivar, David Cortez, Karlene A Cimprich. Nat Rev Mol Cell Biol 2017
328
7

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
730
7


ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Stephanie A Yazinski, Valentine Comaills, Rémi Buisson, Marie-Michelle Genois, Hai Dang Nguyen, Chu Kwen Ho, Tanya Todorova Kwan, Robert Morris, Sam Lauffer, André Nussenzweig,[...]. Genes Dev 2017
191
6

High speed of fork progression induces DNA replication stress and genomic instability.
Apolinar Maya-Mendoza, Pavel Moudry, Joanna Maria Merchut-Maya, MyungHee Lee, Robert Strauss, Jiri Bartek. Nature 2018
201
6

cGAS surveillance of micronuclei links genome instability to innate immunity.
Karen J Mackenzie, Paula Carroll, Carol-Anne Martin, Olga Murina, Adeline Fluteau, Daniel J Simpson, Nelly Olova, Hannah Sutcliffe, Jacqueline K Rainger, Andrea Leitch,[...]. Nature 2017
628
6

The DNA damage response and cancer therapy.
Christopher J Lord, Alan Ashworth. Nature 2012
984
6

PARP inhibitors: Synthetic lethality in the clinic.
Christopher J Lord, Alan Ashworth. Science 2017
6

Signatures of mutational processes in human cancer.
Ludmil B Alexandrov, Serena Nik-Zainal, David C Wedge, Samuel A J R Aparicio, Sam Behjati, Andrew V Biankin, Graham R Bignell, Niccolò Bolli, Ake Borg, Anne-Lise Børresen-Dale,[...]. Nature 2013
6

Replication stress links structural and numerical cancer chromosomal instability.
Rebecca A Burrell, Sarah E McClelland, David Endesfelder, Petra Groth, Marie-Christine Weller, Nadeem Shaikh, Enric Domingo, Nnennaya Kanu, Sally M Dewhurst, Eva Gronroos,[...]. Nature 2013
489
6

Replication stress and oxidative damage contribute to aberrant constitutive activation of DNA damage signalling in human gliomas.
J Bartkova, P Hamerlik, M-T Stockhausen, J Ehrmann, A Hlobilkova, H Laursen, O Kalita, Z Kolar, H S Poulsen, H Broholm,[...]. Oncogene 2010
131
6

Replication stress activates DNA repair synthesis in mitosis.
Sheroy Minocherhomji, Songmin Ying, Victoria A Bjerregaard, Sara Bursomanno, Aiste Aleliunaite, Wei Wu, Hocine W Mankouri, Huahao Shen, Ying Liu, Ian D Hickson. Nature 2015
301
6

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention.
Cristian Tomasetti, Lu Li, Bert Vogelstein. Science 2017
443
6


Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.
Kok Lung Chan, Timea Palmai-Pallag, Songmin Ying, Ian D Hickson. Nat Cell Biol 2009
420
6

Break-induced replication repair of damaged forks induces genomic duplications in human cells.
Lorenzo Costantino, Sotirios K Sotiriou, Juha K Rantala, Simon Magin, Emil Mladenov, Thomas Helleday, James E Haber, George Iliakis, Olli P Kallioniemi, Thanos D Halazonetis. Science 2014
284
6

The landscape of somatic copy-number alteration across human cancers.
Rameen Beroukhim, Craig H Mermel, Dale Porter, Guo Wei, Soumya Raychaudhuri, Jerry Donovan, Jordi Barretina, Jesse S Boehm, Jennifer Dobson, Mitsuyoshi Urashima,[...]. Nature 2010
6

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.
Luis I Toledo, Matilde Murga, Rafal Zur, Rebeca Soria, Antonio Rodriguez, Sonia Martinez, Julen Oyarzabal, Joaquin Pastor, James R Bischoff, Oscar Fernandez-Capetillo. Nat Struct Mol Biol 2011
336
6

Therapeutic opportunities within the DNA damage response.
Laurence H Pearl, Amanda C Schierz, Simon E Ward, Bissan Al-Lazikani, Frances M G Pearl. Nat Rev Cancer 2015
299
6

Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR.
Philip M Reaper, Matthew R Griffiths, Joanna M Long, Jean-Damien Charrier, Somhairle Maccormick, Peter A Charlton, Julian M C Golec, John R Pollard. Nat Chem Biol 2011
402
5

The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
250
5

Mitotic progression following DNA damage enables pattern recognition within micronuclei.
Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg. Nature 2017
592
5

BRCAness revisited.
Christopher J Lord, Alan Ashworth. Nat Rev Cancer 2016
638
5

ATR prohibits replication catastrophe by preventing global exhaustion of RPA.
Luis Ignacio Toledo, Matthias Altmeyer, Maj-Britt Rask, Claudia Lukas, Dorthe Helena Larsen, Lou Klitgaard Povlsen, Simon Bekker-Jensen, Niels Mailand, Jiri Bartek, Jiri Lukas. Cell 2013
482
5

Increased global transcription activity as a mechanism of replication stress in cancer.
Panagiotis Kotsantis, Lara Marques Silva, Sarah Irmscher, Rebecca M Jones, Lisa Folkes, Natalia Gromak, Eva Petermann. Nat Commun 2016
139
5

Replication fork stability confers chemoresistance in BRCA-deficient cells.
Arnab Ray Chaudhuri, Elsa Callen, Xia Ding, Ewa Gogola, Alexandra A Duarte, Ji-Eun Lee, Nancy Wong, Vanessa Lafarga, Jennifer A Calvo, Nicholas J Panzarino,[...]. Nature 2016
431
5

DNA breaks and chromosome pulverization from errors in mitosis.
Karen Crasta, Neil J Ganem, Regina Dagher, Alexandra B Lantermann, Elena V Ivanova, Yunfeng Pan, Luigi Nezi, Alexei Protopopov, Dipanjan Chowdhury, David Pellman. Nature 2012
751
5

Exploiting replicative stress to treat cancer.
Matthias Dobbelstein, Claus Storgaard Sørensen. Nat Rev Drug Discov 2015
175
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.