Systematic review of barriers to the recruitment of older patients with cancer onto clinical trials.
Carol A Townsley, Rita Selby, Lillian L Siu. J Clin Oncol 2005
Times Cited: 397
Times Cited: 397
Times Cited
Times Co-cited
Similarity
Participation in cancer clinical trials: race-, sex-, and age-based disparities.
Vivek H Murthy, Harlan M Krumholz, Cary P Gross. JAMA 2004
Vivek H Murthy, Harlan M Krumholz, Cary P Gross. JAMA 2004
23
Underrepresentation of patients 65 years of age or older in cancer-treatment trials.
L F Hutchins, J M Unger, J J Crowley, C A Coltman, K S Albain. N Engl J Med 1999
L F Hutchins, J M Unger, J J Crowley, C A Coltman, K S Albain. N Engl J Med 1999
21
Participation of patients 65 years of age or older in cancer clinical trials.
Joy H Lewis, Meredith L Kilgore, Dana P Goldman, Edward L Trimble, Richard Kaplan, Michael J Montello, Michael G Housman, José J Escarce. J Clin Oncol 2003
Joy H Lewis, Meredith L Kilgore, Dana P Goldman, Edward L Trimble, Richard Kaplan, Michael J Montello, Michael G Housman, José J Escarce. J Clin Oncol 2003
21
Designing therapeutic clinical trials for older and frail adults with cancer: U13 conference recommendations.
Arti Hurria, William Dale, Margaret Mooney, Julia H Rowland, Karla V Ballman, Harvey J Cohen, Hyman B Muss, Richard L Schilsky, Betty Ferrell, Martine Extermann,[...]. J Clin Oncol 2014
Arti Hurria, William Dale, Margaret Mooney, Julia H Rowland, Karla V Ballman, Harvey J Cohen, Hyman B Muss, Richard L Schilsky, Betty Ferrell, Martine Extermann,[...]. J Clin Oncol 2014
13
Broadening Eligibility Criteria to Make Clinical Trials More Representative: American Society of Clinical Oncology and Friends of Cancer Research Joint Research Statement.
Edward S Kim, Suanna S Bruinooge, Samantha Roberts, Gwynn Ison, Nancy U Lin, Lia Gore, Thomas S Uldrick, Stuart M Lichtman, Nancy Roach, Julia A Beaver,[...]. J Clin Oncol 2017
Edward S Kim, Suanna S Bruinooge, Samantha Roberts, Gwynn Ison, Nancy U Lin, Lia Gore, Thomas S Uldrick, Stuart M Lichtman, Nancy Roach, Julia A Beaver,[...]. J Clin Oncol 2017
12
Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration.
Lilia Talarico, Gang Chen, Richard Pazdur. J Clin Oncol 2004
Lilia Talarico, Gang Chen, Richard Pazdur. J Clin Oncol 2004
12
Understanding the attitudes of the elderly towards enrolment into cancer clinical trials.
Carol A Townsley, Kelvin K Chan, Gregory R Pond, Christine Marquez, Lillian L Siu, Sharon E Straus. BMC Cancer 2006
Carol A Townsley, Kelvin K Chan, Gregory R Pond, Christine Marquez, Lillian L Siu, Sharon E Straus. BMC Cancer 2006
11
Improving the Evidence Base for Treating Older Adults With Cancer: American Society of Clinical Oncology Statement.
Arti Hurria, Laura A Levit, William Dale, Supriya G Mohile, Hyman B Muss, Louis Fehrenbacher, Allison Magnuson, Stuart M Lichtman, Suanna S Bruinooge, Enrique Soto-Perez-de-Celis,[...]. J Clin Oncol 2015
Arti Hurria, Laura A Levit, William Dale, Supriya G Mohile, Hyman B Muss, Louis Fehrenbacher, Allison Magnuson, Stuart M Lichtman, Suanna S Bruinooge, Enrique Soto-Perez-de-Celis,[...]. J Clin Oncol 2015
11
Barriers to clinical trial participation by older women with breast cancer.
M Margaret Kemeny, Bercedis L Peterson, Alice B Kornblith, Hyman B Muss, Judith Wheeler, Ellis Levine, Nancy Bartlett, Gini Fleming, Harvey J Cohen. J Clin Oncol 2003
M Margaret Kemeny, Bercedis L Peterson, Alice B Kornblith, Hyman B Muss, Judith Wheeler, Ellis Levine, Nancy Bartlett, Gini Fleming, Harvey J Cohen. J Clin Oncol 2003
11
Barriers to recruiting underrepresented populations to cancer clinical trials: a systematic review.
Jean G Ford, Mollie W Howerton, Gabriel Y Lai, Tiffany L Gary, Shari Bolen, M Chris Gibbons, Jon Tilburt, Charles Baffi, Teerath Peter Tanpitukpongse, Renee F Wilson,[...]. Cancer 2008
Jean G Ford, Mollie W Howerton, Gabriel Y Lai, Tiffany L Gary, Shari Bolen, M Chris Gibbons, Jon Tilburt, Charles Baffi, Teerath Peter Tanpitukpongse, Renee F Wilson,[...]. Cancer 2008
11
Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment.
P N Lara, R Higdon, N Lim, K Kwan, M Tanaka, D H Lau, T Wun, J Welborn, F J Meyers, S Christensen,[...]. J Clin Oncol 2001
P N Lara, R Higdon, N Lim, K Kwan, M Tanaka, D H Lau, T Wun, J Welborn, F J Meyers, S Christensen,[...]. J Clin Oncol 2001
10
Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Organ Dysfunction, Prior or Concurrent Malignancy, and Comorbidities Working Group.
Stuart M Lichtman, R Donald Harvey, Marie-Anne Damiette Smit, Atiqur Rahman, Michael A Thompson, Nancy Roach, Caroline Schenkel, Suanna S Bruinooge, Patricia Cortazar, Dana Walker,[...]. J Clin Oncol 2017
Stuart M Lichtman, R Donald Harvey, Marie-Anne Damiette Smit, Atiqur Rahman, Michael A Thompson, Nancy Roach, Caroline Schenkel, Suanna S Bruinooge, Patricia Cortazar, Dana Walker,[...]. J Clin Oncol 2017
11
The Role of Clinical Trial Participation in Cancer Research: Barriers, Evidence, and Strategies.
Joseph M Unger, Elise Cook, Eric Tai, Archie Bleyer. Am Soc Clin Oncol Educ Book 2016
Joseph M Unger, Elise Cook, Eric Tai, Archie Bleyer. Am Soc Clin Oncol Educ Book 2016
10
A prospective analysis of the influence of older age on physician and patient decision-making when considering enrollment in breast cancer clinical trials (SWOG S0316).
Sara H Javid, Joseph M Unger, Julie R Gralow, Carol M Moinpour, Antoinette J Wozniak, J Wendall Goodwin, Primo N Lara, Pamela A Williams, Laura F Hutchins, Carolyn C Gotay,[...]. Oncologist 2012
Sara H Javid, Joseph M Unger, Julie R Gralow, Carol M Moinpour, Antoinette J Wozniak, J Wendall Goodwin, Primo N Lara, Pamela A Williams, Laura F Hutchins, Carolyn C Gotay,[...]. Oncologist 2012
13
Predicting the risk of chemotherapy toxicity in older patients: the Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score.
Martine Extermann, Ivette Boler, Richard R Reich, Gary H Lyman, Richard H Brown, Joseph DeFelice, Richard M Levine, Eric T Lubiner, Pablo Reyes, Frederic J Schreiber,[...]. Cancer 2012
Martine Extermann, Ivette Boler, Richard R Reich, Gary H Lyman, Richard H Brown, Joseph DeFelice, Richard M Levine, Eric T Lubiner, Pablo Reyes, Frederic J Schreiber,[...]. Cancer 2012
8
A new method of classifying prognostic comorbidity in longitudinal studies: development and validation.
M E Charlson, P Pompei, K L Ales, C R MacKenzie. J Chronic Dis 1987
M E Charlson, P Pompei, K L Ales, C R MacKenzie. J Chronic Dis 1987
8
Cancer statistics, 2019.
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2019
Rebecca L Siegel, Kimberly D Miller, Ahmedin Jemal. CA Cancer J Clin 2019
8
Practical Assessment and Management of Vulnerabilities in Older Patients Receiving Chemotherapy: ASCO Guideline for Geriatric Oncology.
Supriya G Mohile, William Dale, Mark R Somerfield, Mara A Schonberg, Cynthia M Boyd, Peggy S Burhenn, Beverly Canin, Harvey Jay Cohen, Holly M Holmes, Judith O Hopkins,[...]. J Clin Oncol 2018
Supriya G Mohile, William Dale, Mark R Somerfield, Mara A Schonberg, Cynthia M Boyd, Peggy S Burhenn, Beverly Canin, Harvey Jay Cohen, Holly M Holmes, Judith O Hopkins,[...]. J Clin Oncol 2018
8
Barriers to participation in randomised controlled trials: a systematic review.
S Ross, A Grant, C Counsell, W Gillespie, I Russell, R Prescott. J Clin Epidemiol 1999
S Ross, A Grant, C Counsell, W Gillespie, I Russell, R Prescott. J Clin Epidemiol 1999
7
Future of cancer incidence in the United States: burdens upon an aging, changing nation.
Benjamin D Smith, Grace L Smith, Arti Hurria, Gabriel N Hortobagyi, Thomas A Buchholz. J Clin Oncol 2009
Benjamin D Smith, Grace L Smith, Arti Hurria, Gabriel N Hortobagyi, Thomas A Buchholz. J Clin Oncol 2009
7
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
Freddie Bray, Jacques Ferlay, Isabelle Soerjomataram, Rebecca L Siegel, Lindsey A Torre, Ahmedin Jemal. CA Cancer J Clin 2018
7
Systematic Review and Meta-Analysis of the Magnitude of Structural, Clinical, and Physician and Patient Barriers to Cancer Clinical Trial Participation.
Joseph M Unger, Riha Vaidya, Dawn L Hershman, Lori M Minasian, Mark E Fleury. J Natl Cancer Inst 2019
Joseph M Unger, Riha Vaidya, Dawn L Hershman, Lori M Minasian, Mark E Fleury. J Natl Cancer Inst 2019
7
Disparate inclusion of older adults in clinical trials: priorities and opportunities for policy and practice change.
Angelica P Herrera, Shedra Amy Snipes, Denae W King, Isabel Torres-Vigil, Daniel S Goldberg, Armin D Weinberg. Am J Public Health 2010
Angelica P Herrera, Shedra Amy Snipes, Denae W King, Isabel Torres-Vigil, Daniel S Goldberg, Armin D Weinberg. Am J Public Health 2010
6
Reevaluating Eligibility Criteria - Balancing Patient Protection and Participation in Oncology Trials.
Julia A Beaver, Gwynn Ison, Richard Pazdur. N Engl J Med 2017
Julia A Beaver, Gwynn Ison, Richard Pazdur. N Engl J Med 2017
9
Under-representation of older adults in cancer registration trials: known problem, little progress.
Kevin S Scher, Arti Hurria. J Clin Oncol 2012
Kevin S Scher, Arti Hurria. J Clin Oncol 2012
6
Participation of the elderly population in clinical trials: barriers and solutions.
Aaron C Denson, Amit Mahipal. Cancer Control 2014
Aaron C Denson, Amit Mahipal. Cancer Control 2014
7
Validation of a Prediction Tool for Chemotherapy Toxicity in Older Adults With Cancer.
Arti Hurria, Supriya Mohile, Ajeet Gajra, Heidi Klepin, Hyman Muss, Andrew Chapman, Tao Feng, David Smith, Can-Lan Sun, Nienke De Glas,[...]. J Clin Oncol 2016
Arti Hurria, Supriya Mohile, Ajeet Gajra, Heidi Klepin, Hyman Muss, Andrew Chapman, Tao Feng, David Smith, Can-Lan Sun, Nienke De Glas,[...]. J Clin Oncol 2016
6
Enrollment of older patients in cancer treatment trials in Canada: why is age a barrier?
Karen W L Yee, Joseph L Pater, Lam Pho, Benny Zee, Lillian L Siu. J Clin Oncol 2003
Karen W L Yee, Joseph L Pater, Lam Pho, Benny Zee, Lillian L Siu. J Clin Oncol 2003
6
Expanding the Evidence Base in Geriatric Oncology: Action Items From an FDA-ASCO Workshop.
Laura A Levit, Harpreet Singh, Heidi D Klepin, Arti Hurria. J Natl Cancer Inst 2018
Laura A Levit, Harpreet Singh, Heidi D Klepin, Arti Hurria. J Natl Cancer Inst 2018
14
Difficulties in recruiting older people in clinical trials: an examination of barriers and solutions.
I Ridda, C R MacIntyre, R I Lindley, T C Tan. Vaccine 2010
I Ridda, C R MacIntyre, R I Lindley, T C Tan. Vaccine 2010
8
International Society of Geriatric Oncology consensus on geriatric assessment in older patients with cancer.
Hans Wildiers, Pieter Heeren, Martine Puts, Eva Topinkova, Maryska L G Janssen-Heijnen, Martine Extermann, Claire Falandry, Andrew Artz, Etienne Brain, Giuseppe Colloca,[...]. J Clin Oncol 2014
Hans Wildiers, Pieter Heeren, Martine Puts, Eva Topinkova, Maryska L G Janssen-Heijnen, Martine Extermann, Claire Falandry, Andrew Artz, Etienne Brain, Giuseppe Colloca,[...]. J Clin Oncol 2014
5
Prognostic importance of comorbidity in a hospital-based cancer registry.
Jay F Piccirillo, Ryan M Tierney, Irene Costas, Lori Grove, Edward L Spitznagel. JAMA 2004
Jay F Piccirillo, Ryan M Tierney, Irene Costas, Lori Grove, Edward L Spitznagel. JAMA 2004
5
Public attitudes toward participation in cancer clinical trials.
Robert L Comis, Jon D Miller, Carolyn R Aldigé, Linda Krebs, Ellen Stoval. J Clin Oncol 2003
Robert L Comis, Jon D Miller, Carolyn R Aldigé, Linda Krebs, Ellen Stoval. J Clin Oncol 2003
5
Eligibility criteria of randomized controlled trials published in high-impact general medical journals: a systematic sampling review.
Harriette G C Van Spall, Andrew Toren, Alex Kiss, Robert A Fowler. JAMA 2007
Harriette G C Van Spall, Andrew Toren, Alex Kiss, Robert A Fowler. JAMA 2007
5
Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.
Arti Hurria, Kayo Togawa, Supriya G Mohile, Cynthia Owusu, Heidi D Klepin, Cary P Gross, Stuart M Lichtman, Ajeet Gajra, Smita Bhatia, Vani Katheria,[...]. J Clin Oncol 2011
Arti Hurria, Kayo Togawa, Supriya G Mohile, Cynthia Owusu, Heidi D Klepin, Cary P Gross, Stuart M Lichtman, Ajeet Gajra, Smita Bhatia, Vani Katheria,[...]. J Clin Oncol 2011
5
Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial.
Matthew T Seymour, Lindsay C Thompson, Harpreet S Wasan, Gary Middleton, Alison E Brewster, Stephen F Shepherd, M Sinead O'Mahony, Timothy S Maughan, Mahesh Parmar, Ruth E Langley. Lancet 2011
Matthew T Seymour, Lindsay C Thompson, Harpreet S Wasan, Gary Middleton, Alison E Brewster, Stephen F Shepherd, M Sinead O'Mahony, Timothy S Maughan, Mahesh Parmar, Ruth E Langley. Lancet 2011
5
Comparison of survival outcomes among cancer patients treated in and out of clinical trials.
Joseph M Unger, William E Barlow, Diane P Martin, Scott D Ramsey, Michael Leblanc, Ruth Etzioni, Dawn L Hershman. J Natl Cancer Inst 2014
Joseph M Unger, William E Barlow, Diane P Martin, Scott D Ramsey, Michael Leblanc, Ruth Etzioni, Dawn L Hershman. J Natl Cancer Inst 2014
5
Survey of oncologists' perceptions of barriers to accrual of older patients with breast carcinoma to clinical trials.
Alice B Kornblith, Margaret Kemeny, Bercedis L Peterson, Judith Wheeler, Jeffrey Crawford, Nancy Bartlett, Gini Fleming, Stephen Graziano, Hyman Muss, Harvey Jay Cohen. Cancer 2002
Alice B Kornblith, Margaret Kemeny, Bercedis L Peterson, Judith Wheeler, Jeffrey Crawford, Nancy Bartlett, Gini Fleming, Stephen Graziano, Hyman Muss, Harvey Jay Cohen. Cancer 2002
5
How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trials.
Warren B Sateren, Edward L Trimble, Jeffrey Abrams, Otis Brawley, Nancy Breen, Leslie Ford, Mary McCabe, Richard Kaplan, Malcolm Smith, Richard Ungerleider,[...]. J Clin Oncol 2002
Warren B Sateren, Edward L Trimble, Jeffrey Abrams, Otis Brawley, Nancy Breen, Leslie Ford, Mary McCabe, Richard Kaplan, Malcolm Smith, Richard Ungerleider,[...]. J Clin Oncol 2002
5
Impact of Age on Outcomes with Immunotherapy for Patients with Melanoma.
Allison S Betof, Ryan D Nipp, Anita Giobbie-Hurder, Romany A N Johnpulle, Krista Rubin, Samuel M Rubinstein, Keith T Flaherty, Donald P Lawrence, Douglas B Johnson, Ryan J Sullivan. Oncologist 2017
Allison S Betof, Ryan D Nipp, Anita Giobbie-Hurder, Romany A N Johnpulle, Krista Rubin, Samuel M Rubinstein, Keith T Flaherty, Donald P Lawrence, Douglas B Johnson, Ryan J Sullivan. Oncologist 2017
5
Management of elderly patients with breast cancer: updated recommendations of the International Society of Geriatric Oncology (SIOG) and European Society of Breast Cancer Specialists (EUSOMA).
Laura Biganzoli, Hans Wildiers, Catherine Oakman, Lorenza Marotti, Sibylle Loibl, Ian Kunkler, Malcolm Reed, Stefano Ciatto, Adri C Voogd, Etienne Brain,[...]. Lancet Oncol 2012
Laura Biganzoli, Hans Wildiers, Catherine Oakman, Lorenza Marotti, Sibylle Loibl, Ian Kunkler, Malcolm Reed, Stefano Ciatto, Adri C Voogd, Etienne Brain,[...]. Lancet Oncol 2012
5
Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival.
Mara A Schonberg, Edward R Marcantonio, Donglin Li, Rebecca A Silliman, Long Ngo, Ellen P McCarthy. J Clin Oncol 2010
Mara A Schonberg, Edward R Marcantonio, Donglin Li, Rebecca A Silliman, Long Ngo, Ellen P McCarthy. J Clin Oncol 2010
5
Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.
Hossein Borghaei, Luis Paz-Ares, Leora Horn, David R Spigel, Martin Steins, Neal E Ready, Laura Q Chow, Everett E Vokes, Enriqueta Felip, Esther Holgado,[...]. N Engl J Med 2015
Hossein Borghaei, Luis Paz-Ares, Leora Horn, David R Spigel, Martin Steins, Neal E Ready, Laura Q Chow, Everett E Vokes, Enriqueta Felip, Esther Holgado,[...]. N Engl J Med 2015
5
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial.
Roy S Herbst, Paul Baas, Dong-Wan Kim, Enriqueta Felip, José L Pérez-Gracia, Ji-Youn Han, Julian Molina, Joo-Hang Kim, Catherine Dubos Arvis, Myung-Ju Ahn,[...]. Lancet 2016
Roy S Herbst, Paul Baas, Dong-Wan Kim, Enriqueta Felip, José L Pérez-Gracia, Ji-Youn Han, Julian Molina, Joo-Hang Kim, Catherine Dubos Arvis, Myung-Ju Ahn,[...]. Lancet 2016
5
Elderly patients with advanced NSCLC in phase III clinical trials: are the elderly excluded from practice-changing trials in advanced NSCLC?
Adrian G Sacher, Lisa W Le, Natasha B Leighl, Linda E Coate. J Thorac Oncol 2013
Adrian G Sacher, Lisa W Le, Natasha B Leighl, Linda E Coate. J Thorac Oncol 2013
7
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1).
E A Eisenhauer, P Therasse, J Bogaerts, L H Schwartz, D Sargent, R Ford, J Dancey, S Arbuck, S Gwyther, M Mooney,[...]. Eur J Cancer 2009
E A Eisenhauer, P Therasse, J Bogaerts, L H Schwartz, D Sargent, R Ford, J Dancey, S Arbuck, S Gwyther, M Mooney,[...]. Eur J Cancer 2009
5
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.
David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman. PLoS Med 2009
David Moher, Alessandro Liberati, Jennifer Tetzlaff, Douglas G Altman. PLoS Med 2009
5
Screening older cancer patients: first evaluation of the G-8 geriatric screening tool.
C A Bellera, M Rainfray, S Mathoulin-Pélissier, C Mertens, F Delva, M Fonck, P L Soubeyran. Ann Oncol 2012
C A Bellera, M Rainfray, S Mathoulin-Pélissier, C Mertens, F Delva, M Fonck, P L Soubeyran. Ann Oncol 2012
5
Factors Associated With Age Disparities Among Cancer Clinical Trial Participants.
Ethan B Ludmir, Walker Mainwaring, Timothy A Lin, Austin B Miller, Amit Jethanandani, Andres F Espinoza, Jacob J Mandel, Steven H Lin, Benjamin D Smith, Grace L Smith,[...]. JAMA Oncol 2019
Ethan B Ludmir, Walker Mainwaring, Timothy A Lin, Austin B Miller, Amit Jethanandani, Andres F Espinoza, Jacob J Mandel, Steven H Lin, Benjamin D Smith, Grace L Smith,[...]. JAMA Oncol 2019
6
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.
Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray. Int J Cancer 2015
Jacques Ferlay, Isabelle Soerjomataram, Rajesh Dikshit, Sultan Eser, Colin Mathers, Marise Rebelo, Donald Maxwell Parkin, David Forman, Freddie Bray. Int J Cancer 2015
4
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.