Mei Qin, Julia Kang, Thomas V Burlin, Chunhui Jiang, Carolyn Beebe Smith. J Neurosci 2005
Times Cited: 169
Times Cited: 169
Times Cited
Times Co-cited
Similarity
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
Jennifer C Darnell, Sarah J Van Driesche, Chaolin Zhang, Ka Ying Sharon Hung, Aldo Mele, Claire E Fraser, Elizabeth F Stone, Cynthia Chen, John J Fak, Sung Wook Chi,[...]. Cell 2011
59
Correction of fragile X syndrome in mice.
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
Gül Dölen, Emily Osterweil, B S Shankaranarayana Rao, Gordon B Smith, Benjamin D Auerbach, Sumantra Chattarji, Mark F Bear. Neuron 2007
57
Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome.
Emily K Osterweil, Dilja D Krueger, Kimberly Reinhold, Mark F Bear. J Neurosci 2010
Emily K Osterweil, Dilja D Krueger, Kimberly Reinhold, Mark F Bear. J Neurosci 2010
57
Dysregulation of mTOR signaling in fragile X syndrome.
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
Ali Sharma, Charles A Hoeffer, Yukihiro Takayasu, Takahiro Miyawaki, Sean M McBride, Eric Klann, R Suzanne Zukin. J Neurosci 2010
42
The mGluR theory of fragile X mental retardation.
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
Mark F Bear, Kimberly M Huber, Stephen T Warren. Trends Neurosci 2004
40
Altered synaptic plasticity in a mouse model of fragile X mental retardation.
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
Kimberly M Huber, Sean M Gallagher, Stephen T Warren, Mark F Bear. Proc Natl Acad Sci U S A 2002
39
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice.
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
Aubin Michalon, Michael Sidorov, Theresa M Ballard, Laurence Ozmen, Will Spooren, Joseph G Wettstein, Georg Jaeschke, Mark F Bear, Lothar Lindemann. Neuron 2012
34
Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome.
Emily K Osterweil, Shih-Chieh Chuang, Alexander A Chubykin, Michael Sidorov, Riccardo Bianchi, Robert K S Wong, Mark F Bear. Neuron 2013
Emily K Osterweil, Shih-Chieh Chuang, Alexander A Chubykin, Michael Sidorov, Riccardo Bianchi, Robert K S Wong, Mark F Bear. Neuron 2013
30
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP.
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
Ilaria Napoli, Valentina Mercaldo, Pietro Pilo Boyl, Boris Eleuteri, Francesca Zalfa, Silvia De Rubeis, Daniele Di Marino, Evita Mohr, Marzia Massimi, Mattia Falconi,[...]. Cell 2008
29
Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C Alvarez-Dieppa, Jaclyn P Murphy, Philippe Pierre, Eric Klann. Neuron 2012
Aditi Bhattacharya, Hanoch Kaphzan, Amanda C Alvarez-Dieppa, Jaclyn P Murphy, Philippe Pierre, Eric Klann. Neuron 2012
29
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
A J Verkerk, M Pieretti, J S Sutcliffe, Y H Fu, D P Kuhl, A Pizzuti, O Reiner, S Richards, M F Victoria, F P Zhang. Cell 1991
26
Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
V Brown, P Jin, S Ceman, J C Darnell, W T O'Donnell, S A Tenenbaum, X Jin, Y Feng, K D Wilkinson, J D Keene,[...]. Cell 2001
26
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
Christina Gross, Mika Nakamoto, Xiaodi Yao, Chi-Bun Chan, So Y Yim, Keqiang Ye, Stephen T Warren, Gary J Bassell. J Neurosci 2010
26
Evidence that fragile X mental retardation protein is a negative regulator of translation.
B Laggerbauer, D Ostareck, E M Keidel, A Ostareck-Lederer, U Fischer. Hum Mol Genet 2001
B Laggerbauer, D Ostareck, E M Keidel, A Ostareck-Lederer, U Fischer. Hum Mol Genet 2001
26
The translation of translational control by FMRP: therapeutic targets for FXS.
Jennifer C Darnell, Eric Klann. Nat Neurosci 2013
Jennifer C Darnell, Eric Klann. Nat Neurosci 2013
26
The fragile X mental retardation protein inhibits translation via interacting with mRNA.
Z Li, Y Zhang, L Ku, K D Wilkinson, S T Warren, Y Feng. Nucleic Acids Res 2001
Z Li, Y Zhang, L Ku, K D Wilkinson, S T Warren, Y Feng. Nucleic Acids Res 2001
24
Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.
Gary J Bassell, Stephen T Warren. Neuron 2008
Gary J Bassell, Stephen T Warren. Neuron 2008
22
Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression.
K M Huber, M S Kayser, M F Bear. Science 2000
K M Huber, M S Kayser, M F Bear. Science 2000
22
Mutations causing syndromic autism define an axis of synaptic pathophysiology.
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
Benjamin D Auerbach, Emily K Osterweil, Mark F Bear. Nature 2011
22
Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.
Lingfei Hou, Marcia D Antion, Daoying Hu, Corinne M Spencer, Richard Paylor, Eric Klann. Neuron 2006
Lingfei Hou, Marcia D Antion, Daoying Hu, Corinne M Spencer, Richard Paylor, Eric Klann. Neuron 2006
21
Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits.
T A Comery, J B Harris, P J Willems, B A Oostra, S A Irwin, I J Weiler, W T Greenough. Proc Natl Acad Sci U S A 1997
T A Comery, J B Harris, P J Willems, B A Oostra, S A Irwin, I J Weiler, W T Greenough. Proc Natl Acad Sci U S A 1997
21
Molecular mechanisms of fragile X syndrome: a twenty-year perspective.
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
Michael R Santoro, Steven M Bray, Stephen T Warren. Annu Rev Pathol 2012
19
Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen.
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Friso R Postma, Christopher Brynczka, Roger Rush, Alexia Thomas, Richard Paylor,[...]. Sci Transl Med 2012
Christina Henderson, Lasani Wijetunge, Mika Nakamoto Kinoshita, Matthew Shumway, Rebecca S Hammond, Friso R Postma, Christopher Brynczka, Roger Rush, Alexia Thomas, Richard Paylor,[...]. Sci Transl Med 2012
19
Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling.
Ravi S Muddashetty, Vijayalaxmi C Nalavadi, Christina Gross, Xiaodi Yao, Lei Xing, Oskar Laur, Stephen T Warren, Gary J Bassell. Mol Cell 2011
Ravi S Muddashetty, Vijayalaxmi C Nalavadi, Christina Gross, Xiaodi Yao, Lei Xing, Oskar Laur, Stephen T Warren, Gary J Bassell. Mol Cell 2011
17
Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model.
T V Bilousova, L Dansie, M Ngo, J Aye, J R Charles, D W Ethell, I M Ethell. J Med Genet 2009
T V Bilousova, L Dansie, M Ngo, J Aye, J R Charles, D W Ethell, I M Ethell. J Med Genet 2009
17
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses.
Francesca Zalfa, Marcello Giorgi, Beatrice Primerano, Annamaria Moro, Alessandra Di Penta, Surya Reis, Ben Oostra, Claudia Bagni. Cell 2003
Francesca Zalfa, Marcello Giorgi, Beatrice Primerano, Annamaria Moro, Alessandra Di Penta, Surya Reis, Ben Oostra, Claudia Bagni. Cell 2003
17
Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory.
François V Bolduc, Kimberly Bell, Hilary Cox, Kendal S Broadie, Tim Tully. Nat Neurosci 2008
François V Bolduc, Kimberly Bell, Hilary Cox, Kendal S Broadie, Tim Tully. Nat Neurosci 2008
17
FMR1 protein: conserved RNP family domains and selective RNA binding.
C T Ashley, K D Wilkinson, D Reines, S T Warren. Science 1993
C T Ashley, K D Wilkinson, D Reines, S T Warren. Science 1993
17
Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium.
. Cell 1994
. Cell 1994
17
Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function.
J C Darnell, K B Jensen, P Jin, V Brown, S T Warren, R B Darnell. Cell 2001
J C Darnell, K B Jensen, P Jin, V Brown, S T Warren, R B Darnell. Cell 2001
16
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056.
Sébastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Giulia Torrioli, Elizabeth Berry-Kravis, Randi J Hagerman, Feliciano J Ramos, Kim Cornish, Yunsheng He, Charles Paulding,[...]. Sci Transl Med 2011
Sébastien Jacquemont, Aurore Curie, Vincent des Portes, Maria Giulia Torrioli, Elizabeth Berry-Kravis, Randi J Hagerman, Feliciano J Ramos, Kim Cornish, Yunsheng He, Charles Paulding,[...]. Sci Transl Med 2011
16
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome.
C A Hoeffer, E Sanchez, R J Hagerman, Y Mu, D V Nguyen, H Wong, A M Whelan, R S Zukin, E Klann, F Tassone. Genes Brain Behav 2012
C A Hoeffer, E Sanchez, R J Hagerman, Y Mu, D V Nguyen, H Wong, A M Whelan, R S Zukin, E Klann, F Tassone. Genes Brain Behav 2012
16
Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice.
Mei Qin, Kathleen C Schmidt, Alan J Zametkin, Shrinivas Bishu, Lisa M Horowitz, Thomas V Burlin, Zengyan Xia, Tianjiang Huang, Zenaide M Quezado, Carolyn Beebe Smith. J Cereb Blood Flow Metab 2013
Mei Qin, Kathleen C Schmidt, Alan J Zametkin, Shrinivas Bishu, Lisa M Horowitz, Thomas V Burlin, Zengyan Xia, Tianjiang Huang, Zenaide M Quezado, Carolyn Beebe Smith. J Cereb Blood Flow Metab 2013
47
Dysregulation and restoration of translational homeostasis in fragile X syndrome.
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
Joel D Richter, Gary J Bassell, Eric Klann. Nat Rev Neurosci 2015
16
Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.
Ravi S Muddashetty, Sofija Kelić, Christina Gross, Mei Xu, Gary J Bassell. J Neurosci 2007
Ravi S Muddashetty, Sofija Kelić, Christina Gross, Mei Xu, Gary J Bassell. J Neurosci 2007
15
FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association.
Y Feng, D Absher, D E Eberhart, V Brown, H E Malter, S T Warren. Mol Cell 1997
Y Feng, D Absher, D E Eberhart, V Brown, H E Malter, S T Warren. Mol Cell 1997
15
Dendritic spine structural anomalies in fragile-X mental retardation syndrome.
S A Irwin, R Galvez, W T Greenough. Cereb Cortex 2000
S A Irwin, R Galvez, W T Greenough. Cereb Cortex 2000
15
Toward fulfilling the promise of molecular medicine in fragile X syndrome.
Dilja D Krueger, Mark F Bear. Annu Rev Med 2011
Dilja D Krueger, Mark F Bear. Annu Rev Med 2011
15
FMRP targets distinct mRNA sequence elements to regulate protein expression.
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
Manuel Ascano, Neelanjan Mukherjee, Pradeep Bandaru, Jason B Miller, Jeffrey D Nusbaum, David L Corcoran, Christine Langlois, Mathias Munschauer, Scott Dewell, Markus Hafner,[...]. Nature 2012
15
GSK3 influences social preference and anxiety-related behaviors during social interaction in a mouse model of fragile X syndrome and autism.
Marjelo A Mines, Christopher J Yuskaitis, Margaret K King, Eleonore Beurel, Richard S Jope. PLoS One 2010
Marjelo A Mines, Christopher J Yuskaitis, Margaret K King, Eleonore Beurel, Richard S Jope. PLoS One 2010
14
Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.
Elena D Nosyreva, Kimberly M Huber. J Neurophysiol 2006
Elena D Nosyreva, Kimberly M Huber. J Neurophysiol 2006
14
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
Dan Ehninger, Sangyeul Han, Carrie Shilyansky, Yu Zhou, Weidong Li, David J Kwiatkowski, Vijaya Ramesh, Alcino J Silva. Nat Med 2008
14
Lithium reverses increased rates of cerebral protein synthesis in a mouse model of fragile X syndrome.
Zhong-Hua Liu, Tianjian Huang, Carolyn Beebe Smith. Neurobiol Dis 2012
Zhong-Hua Liu, Tianjian Huang, Carolyn Beebe Smith. Neurobiol Dis 2012
29
The pathophysiology of fragile X (and what it teaches us about synapses).
Asha L Bhakar, Gül Dölen, Mark F Bear. Annu Rev Neurosci 2012
Asha L Bhakar, Gül Dölen, Mark F Bear. Annu Rev Neurosci 2012
14
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation.
I J Weiler, S A Irwin, A Y Klintsova, C M Spencer, A D Brazelton, K Miyashiro, T A Comery, B Patel, J Eberwine, W T Greenough. Proc Natl Acad Sci U S A 1997
I J Weiler, S A Irwin, A Y Klintsova, C M Spencer, A D Brazelton, K Miyashiro, T A Comery, B Patel, J Eberwine, W T Greenough. Proc Natl Acad Sci U S A 1997
13
Suppression of two major Fragile X Syndrome mouse model phenotypes by the mGluR5 antagonist MPEP.
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
Q J Yan, M Rammal, M Tranfaglia, R P Bauchwitz. Neuropharmacology 2005
13
Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial.
Elizabeth M Berry-Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Yi Mu, Danh V Nguyen, Joseph Gonzalez-Heydrich, Paul P Wang,[...]. Sci Transl Med 2012
Elizabeth M Berry-Kravis, David Hessl, Barbara Rathmell, Peter Zarevics, Maryann Cherubini, Karen Walton-Bowen, Yi Mu, Danh V Nguyen, Joseph Gonzalez-Heydrich, Paul P Wang,[...]. Sci Transl Med 2012
13
Genetic and acute CPEB1 depletion ameliorate fragile X pathophysiology.
Tsuyoshi Udagawa, Natalie G Farny, Mira Jakovcevski, Hanoch Kaphzan, Juan Marcos Alarcon, Shobha Anilkumar, Maria Ivshina, Jessica A Hurt, Kentaro Nagaoka, Vijayalaxmi C Nalavadi,[...]. Nat Med 2013
Tsuyoshi Udagawa, Natalie G Farny, Mira Jakovcevski, Hanoch Kaphzan, Juan Marcos Alarcon, Shobha Anilkumar, Maria Ivshina, Jessica A Hurt, Kentaro Nagaoka, Vijayalaxmi C Nalavadi,[...]. Nat Med 2013
15
Absence of expression of the FMR-1 gene in fragile X syndrome.
M Pieretti, F P Zhang, Y H Fu, S T Warren, B A Oostra, C T Caskey, D L Nelson. Cell 1991
M Pieretti, F P Zhang, Y H Fu, S T Warren, B A Oostra, C T Caskey, D L Nelson. Cell 1991
12
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.