A citation-based method for searching scientific literature

Daniel P Ryan, Jacqueline M Matthews. Curr Opin Struct Biol 2005
Times Cited: 198







List of co-cited articles
524 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity



Small molecules, big targets: drug discovery faces the protein-protein interaction challenge.
Duncan E Scott, Andrew R Bayly, Chris Abell, John Skidmore. Nat Rev Drug Discov 2016
527
13



Inhibition of α-helix-mediated protein-protein interactions using designed molecules.
Valeria Azzarito, Kérya Long, Natasha S Murphy, Andrew J Wilson. Nat Chem 2013
452
11

Targeting protein-protein interactions as an anticancer strategy.
Andrei A Ivanov, Fadlo R Khuri, Haian Fu. Trends Pharmacol Sci 2013
203
11

Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes.
Marta Pelay-Gimeno, Adrian Glas, Oliver Koch, Tom N Grossmann. Angew Chem Int Ed Engl 2015
375
11

Principles of protein-protein interactions: what are the preferred ways for proteins to interact?
Ozlem Keskin, Attila Gursoy, Buyong Ma, Ruth Nussinov. Chem Rev 2008
404
10

Estimating the size of the human interactome.
Michael P H Stumpf, Thomas Thorne, Eric de Silva, Ronald Stewart, Hyeong Jun An, Michael Lappe, Carsten Wiuf. Proc Natl Acad Sci U S A 2008
432
10

Hot spots--a review of the protein-protein interface determinant amino-acid residues.
Irina S Moreira, Pedro A Fernandes, Maria J Ramos. Proteins 2007
486
10

Chapter 4: Protein interactions and disease.
Mileidy W Gonzalez, Maricel G Kann. PLoS Comput Biol 2012
128
10



Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
P H Kussie, S Gorina, V Marechal, B Elenbaas, J Moreau, A J Levine, N P Pavletich. Science 1996
9

Anatomy of hot spots in protein interfaces.
A A Bogan, K S Thorn. J Mol Biol 1998
9

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.
Lyubomir T Vassilev, Binh T Vu, Bradford Graves, Daisy Carvajal, Frank Podlaski, Zoran Filipovic, Norman Kong, Ursula Kammlott, Christine Lukacs, Christian Klein,[...]. Science 2004
9


Modulators of protein-protein interactions.
Lech-Gustav Milroy, Tom N Grossmann, Sven Hennig, Luc Brunsveld, Christian Ottmann. Chem Rev 2014
284
7

Transient protein-protein interactions: structural, functional, and network properties.
James R Perkins, Ilhem Diboun, Benoit H Dessailly, Jon G Lees, Christine Orengo. Structure 2010
330
7

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB.
James A Maier, Carmenza Martinez, Koushik Kasavajhala, Lauren Wickstrom, Kevin E Hauser, Carlos Simmerling. J Chem Theory Comput 2015
7

Systematic Targeting of Protein-Protein Interactions.
Ashley E Modell, Sarah L Blosser, Paramjit S Arora. Trends Pharmacol Sci 2016
89
7

Hydrocarbon-stapled peptides: principles, practice, and progress.
Loren D Walensky, Gregory H Bird. J Med Chem 2014
427
6


Oncogenic protein interfaces: small molecules, big challenges.
Tracy L Nero, Craig J Morton, Jessica K Holien, Jerome Wielens, Michael W Parker. Nat Rev Cancer 2014
175
6

Principles of protein-protein interactions.
S Jones, J M Thornton. Proc Natl Acad Sci U S A 1996
6


Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.
Federico Bernal, Andrew F Tyler, Stanley J Korsmeyer, Loren D Walensky, Gregory L Verdine. J Am Chem Soc 2007
375
6

The Protein Data Bank.
H M Berman, J Westbrook, Z Feng, G Gilliland, T N Bhat, H Weissig, I N Shindyalov, P E Bourne. Nucleic Acids Res 2000
6

A human protein-protein interaction network: a resource for annotating the proteome.
Ulrich Stelzl, Uwe Worm, Maciej Lalowski, Christian Haenig, Felix H Brembeck, Heike Goehler, Martin Stroedicke, Martina Zenkner, Anke Schoenherr, Susanne Koeppen,[...]. Cell 2005
5

Peptide stapling techniques based on different macrocyclisation chemistries.
Yu Heng Lau, Peterson de Andrade, Yuteng Wu, David R Spring. Chem Soc Rev 2015
286
5

Diversity of protein-protein interactions.
Irene M A Nooren, Janet M Thornton. EMBO J 2003
541
5

Development of α-helical calpain probes by mimicking a natural protein-protein interaction.
Hyunil Jo, Nataline Meinhardt, Yibing Wu, Swapnil Kulkarni, Xiaozhen Hu, Kristin E Low, Peter L Davies, William F DeGrado, Doron C Greenbaum. J Am Chem Soc 2012
158
5

A Thiol-Ene Coupling Approach to Native Peptide Stapling and Macrocyclization.
Yuanxiang Wang, Danny Hung-Chieh Chou. Angew Chem Int Ed Engl 2015
107
5

In silico design of low molecular weight protein-protein interaction inhibitors: Overall concept and recent advances.
Mélaine A Kuenemann, Olivier Sperandio, Céline M Labbé, David Lagorce, Maria A Miteva, Bruno O Villoutreix. Prog Biophys Mol Biol 2015
40
12


Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
Marzena Pazgier, Min Liu, Guozhang Zou, Weirong Yuan, Changqing Li, Chong Li, Jing Li, Juahdi Monbo, Davide Zella, Sergey G Tarasov,[...]. Proc Natl Acad Sci U S A 2009
249
5

Development and testing of a general amber force field.
Junmei Wang, Romain M Wolf, James W Caldwell, Peter A Kollman, David A Case. J Comput Chem 2004
5


UCSF Chimera--a visualization system for exploratory research and analysis.
Eric F Pettersen, Thomas D Goddard, Conrad C Huang, Gregory S Couch, Daniel M Greenblatt, Elaine C Meng, Thomas E Ferrin. J Comput Chem 2004
5

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Loren D Walensky, Andrew L Kung, Iris Escher, Thomas J Malia, Scott Barbuto, Renee D Wright, Gerhard Wagner, Gregory L Verdine, Stanley J Korsmeyer. Science 2004
973
5

ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers.
Brian G Pierce, Kevin Wiehe, Howook Hwang, Bong-Hyun Kim, Thom Vreven, Zhiping Weng. Bioinformatics 2014
860
5

Modulation of Protein-Protein Interactions for the Development of Novel Therapeutics.
Ioanna Petta, Sam Lievens, Claude Libert, Jan Tavernier, Karolien De Bosscher. Mol Ther 2016
90
5

Peptide therapeutics: current status and future directions.
Keld Fosgerau, Torsten Hoffmann. Drug Discov Today 2015
5

Modulating protein-protein interactions: the potential of peptides.
Laura Nevola, Ernest Giralt. Chem Commun (Camb) 2015
152
5

Protein-protein interactions as a target for drugs in proteomics.
Alexander I Archakov, Vadim M Govorun, Alexander V Dubanov, Yuri D Ivanov, Alexander V Veselovsky, Paul Lewi, Paul Janssen. Proteomics 2003
130
4

Electrostatic aspects of protein-protein interactions.
F B Sheinerman, R Norel, B Honig. Curr Opin Struct Biol 2000
528
4

A perfluoroaryl-cysteine S(N)Ar chemistry approach to unprotected peptide stapling.
Alexander M Spokoyny, Yekui Zou, Jingjing J Ling, Hongtao Yu, Yu-Shan Lin, Bradley L Pentelute. J Am Chem Soc 2013
259
4

Targeting protein-protein interaction by small molecules.
Lingyan Jin, Weiru Wang, Guowei Fang. Annu Rev Pharmacol Toxicol 2014
122
4


An empirical framework for binary interactome mapping.
Kavitha Venkatesan, Jean-François Rual, Alexei Vazquez, Ulrich Stelzl, Irma Lemmens, Tomoko Hirozane-Kishikawa, Tong Hao, Martina Zenkner, Xiaofeng Xin, Kwang-Il Goh,[...]. Nat Methods 2009
573
4


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.