A citation-based method for searching scientific literature

Erich Roessler, Alexandre N Ermilov, Dorothy Katherine Grange, Aiqin Wang, Marina Grachtchouk, Andrzej A Dlugosz, Maximilian Muenke. Hum Mol Genet 2005
Times Cited: 127







List of co-cited articles
982 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features.
Erich Roessler, Yang-Zhu Du, Jose L Mullor, Esther Casas, William P Allen, Gabriele Gillessen-Kaesbach, Elizabeth R Roeder, Jeffrey E Ming, Ariel Ruiz i Altaba, Maximilian Muenke. Proc Natl Acad Sci U S A 2003
238
33


Gli proteins in development and disease.
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
455
19

Pathogenic mutations in GLI2 cause a specific phenotype that is distinct from holoprosencephaly.
Kelly A Bear, Benjamin D Solomon, Sonir Antonini, Ivo J P Arnhold, Marcela M França, Erica H Gerkes, Dorothy K Grange, Donald W Hadley, Jarmo Jääskeläinen, Sabrina S Paulo,[...]. J Med Genet 2014
40
42

Novel heterozygous nonsense GLI2 mutations in patients with hypopituitarism and ectopic posterior pituitary lobe without holoprosencephaly.
Marcela M França, Alexander A L Jorge, Luciani R S Carvalho, Everlayny F Costalonga, Gabriela A Vasques, Claudia C Leite, Berenice B Mendonca, Ivo J P Arnhold. J Clin Endocrinol Metab 2010
73
21

GLI2 mutations in four Brazilian patients: how wide is the phenotypic spectrum?
Fedik Rahimov, Lucilene Arilho Ribeiro, Eziquiel de Miranda, Antonio Richieri-Costa, Jeffrey C Murray. Am J Med Genet A 2006
43
34

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly.
E Roessler, E Belloni, K Gaudenz, P Jay, P Berta, S W Scherer, L C Tsui, M Muenke. Nat Genet 1996
859
14

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.
Matthias Lauth, Asa Bergström, Takashi Shimokawa, Rune Toftgård. Proc Natl Acad Sci U S A 2007
583
14

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo.
Sylviane Dennler, Jocelyne André, Ismini Alexaki, Allen Li, Thierry Magnaldo, Peter ten Dijke, Xiao-Jing Wang, Franck Verrecchia, Alain Mauviel. Cancer Res 2007
277
14

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
14

Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.
C Brian Bai, Wojtek Auerbach, Joon S Lee, Daniel Stephen, Alexandra L Joyner. Development 2002
510
13


Hedgehog: functions and mechanisms.
Markku Varjosalo, Jussi Taipale. Genes Dev 2008
856
12

Hedgehog beyond medulloblastoma and basal cell carcinoma.
Stephan Teglund, Rune Toftgård. Biochim Biophys Acta 2010
334
12

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.
H L Park, C Bai, K A Platt, M P Matise, A Beeghly, C C Hui, M Nakashima, A L Joyner. Development 2000
517
12

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
Yong Pan, Chunyang Brian Bai, Alexandra L Joyner, Baolin Wang. Mol Cell Biol 2006
390
12

Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development.
R Mo, A M Freer, D L Zinyk, M A Crackower, J Michaud, H H Heng, K W Chik, X M Shi, L C Tsui, S H Cheng,[...]. Development 1997
472
12

Clinical findings in patients with GLI2 mutations--phenotypic variability.
C D P Bertolacini, L A Ribeiro-Bicudo, A Petrin, A Richieri-Costa, J C Murray. Clin Genet 2012
42
28

Analysis of genotype-phenotype correlations in human holoprosencephaly.
Benjamin D Solomon, Sandra Mercier, Jorge I Vélez, Daniel E Pineda-Alvarez, Adrian Wyllie, Nan Zhou, Christèle Dubourg, Veronique David, Sylvie Odent, Erich Roessler,[...]. Am J Med Genet C Semin Med Genet 2010
108
11

Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination.
K W Gripp, D Wotton, M C Edwards, E Roessler, L Ades, P Meinecke, A Richieri-Costa, E H Zackai, J Massagué, M Muenke,[...]. Nat Genet 2000
304
11

Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
11

Small molecule modulation of Smoothened activity.
James K Chen, Jussi Taipale, Keith E Young, Tapan Maiti, Philip A Beachy. Proc Natl Acad Sci U S A 2002
763
11

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
11


Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
Barbara Stecca, Christophe Mas, Virginie Clement, Marie Zbinden, Rafael Correa, Vincent Piguet, Friedrich Beermann, Ariel Ruiz i Altaba. Proc Natl Acad Sci U S A 2007
389
11

Relatively high frequency of non-synonymous GLI2 variants in patients with congenital hypopituitarism without holoprosencephaly.
Marcela M França, Alexander A L Jorge, Luciani R S Carvalho, Everlayny F Costalonga, Aline P Otto, Fernanda A Correa, Berenice B Mendonca, Ivo J P Arnhold. Clin Endocrinol (Oxf) 2013
26
42

Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus.
J Motoyama, J Liu, R Mo, Q Ding, M Post, C C Hui. Nat Genet 1998
411
10

Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly.
Jeffrey E Ming, Michelle E Kaupas, Erich Roessler, Han G Brunner, Mahin Golabi, Mustafa Tekin, Robert F Stratton, Eva Sujansky, Sherri J Bale, Maximilian Muenke. Hum Genet 2002
161
10

Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly.
D E Wallis, E Roessler, U Hehr, L Nanni, T Wiltshire, A Richieri-Costa, G Gillessen-Kaesbach, E H Zackai, J Rommens, M Muenke. Nat Genet 1999
286
10

Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired.
S A Brown, D Warburton, L Y Brown, C Y Yu, E R Roeder, S Stengel-Rutkowski, R C Hennekam, M Muenke. Nat Genet 1998
370
10


The molecular genetics of holoprosencephaly.
Erich Roessler, Maximilian Muenke. Am J Med Genet C Semin Med Genet 2010
160
10


Functional characterization of a heterozygous GLI2 missense mutation in patients with multiple pituitary hormone deficiency.
G M C Flemming, J Klammt, G Ambler, Y Bao, W F Blum, C Cowell, K Donaghue, N Howard, A Kumar, J Sanchez,[...]. J Clin Endocrinol Metab 2013
26
38

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
David M Berman, Sunil S Karhadkar, Anirban Maitra, Rocio Montes De Oca, Meg R Gerstenblith, Kimberly Briggs, Antony R Parker, Yutaka Shimada, James R Eshleman, D Neil Watkins,[...]. Nature 2003
9

The full spectrum of holoprosencephaly-associated mutations within the ZIC2 gene in humans predicts loss-of-function as the predominant disease mechanism.
Erich Roessler, Felicitas Lacbawan, Christèle Dubourg, Aimee Paulussen, Jos Herbergs, Ute Hehr, Claude Bendavid, Nan Zhou, Maia Ouspenskaia, Sherri Bale,[...]. Hum Mutat 2009
50
18

Functional analysis of mutations in TGIF associated with holoprosencephaly.
Kenia B El-Jaick, Shannon E Powers, Laurent Bartholin, Kenneth R Myers, Jin Hahn, Ieda M Orioli, Maia Ouspenskaia, Felicitas Lacbawan, Erich Roessler, David Wotton,[...]. Mol Genet Metab 2007
57
15

Truncating loss-of-function mutations of DISP1 contribute to holoprosencephaly-like microform features in humans.
Erich Roessler, Yong Ma, Maia V Ouspenskaia, Felicitas Lacbawan, Claude Bendavid, Christèle Dubourg, Philip A Beachy, Maximilian Muenke. Hum Genet 2009
51
17


The mutational spectrum of holoprosencephaly-associated changes within the SHH gene in humans predicts loss-of-function through either key structural alterations of the ligand or its altered synthesis.
Erich Roessler, Kenia B El-Jaick, Christèle Dubourg, Jorge I Vélez, Benjamin D Solomon, Daniel E Pineda-Alvarez, Felicitas Lacbawan, Nan Zhou, Maia Ouspenskaia, Aimée Paulussen,[...]. Hum Mutat 2009
64
14

Hedgehog signaling in development and cancer.
Jin Jiang, Chi-Chung Hui. Dev Cell 2008
760
9

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer.
Monique T Barakat, Eric W Humke, Matthew P Scott. Trends Mol Med 2010
162
9

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
314
9

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
989
9


Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells.
Zhenyu Ji, Fang C Mei, Jingwu Xie, Xiaodong Cheng. J Biol Chem 2007
225
9

Role of GLI2 in hypopituitarism phenotype.
Ivo J P Arnhold, Marcela M França, Luciani R Carvalho, Berenice B Mendonca, Alexander A L Jorge. J Mol Endocrinol 2015
38
23

Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma.
Gerhard Regl, Graham W Neill, Thomas Eichberger, Maria Kasper, Mohammed S Ikram, Josef Koller, Helmut Hintner, Anthony G Quinn, Anna-Maria Frischauf, Fritz Aberger. Oncogene 2002
159
8

Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice.
Q Ding, J Motoyama, S Gasca, R Mo, H Sasaki, J Rossant, C C Hui. Development 1998
351
8

Mutations in the human SIX3 gene in holoprosencephaly are loss of function.
Sabina Domené, Erich Roessler, Kenia B El-Jaick, Mirit Snir, Jamie L Brown, Jorge I Vélez, Sherri Bale, Felicitas Lacbawan, Maximilian Muenke, Benjamin Feldman. Hum Mol Genet 2008
42
19


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.