Mario F Fraga, Esteban Ballestar, Maria F Paz, Santiago Ropero, Fernando Setien, Maria L Ballestar, Damia Heine-Suñer, Juan C Cigudosa, Miguel Urioste, Javier Benitez, Manuel Boix-Chornet, Abel Sanchez-Aguilera, Charlotte Ling, Emma Carlsson, Pernille Poulsen, Allan Vaag, Zarko Stephan, Tim D Spector, Yue-Zhong Wu, Christoph Plass, Manel Esteller. Proc Natl Acad Sci U S A 2005
Times Cited: 1995
Times Cited: 1995
Times Cited
Times Co-cited
Similarity
Genome-wide methylation profiles reveal quantitative views of human aging rates.
Gregory Hannum, Justin Guinney, Ling Zhao, Li Zhang, Guy Hughes, SriniVas Sadda, Brandy Klotzle, Marina Bibikova, Jian-Bing Fan, Yuan Gao,[...]. Mol Cell 2013
Gregory Hannum, Justin Guinney, Ling Zhao, Li Zhang, Guy Hughes, SriniVas Sadda, Brandy Klotzle, Marina Bibikova, Jian-Bing Fan, Yuan Gao,[...]. Mol Cell 2013
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DNA methylation-based biomarkers and the epigenetic clock theory of ageing.
Steve Horvath, Kenneth Raj. Nat Rev Genet 2018
Steve Horvath, Kenneth Raj. Nat Rev Genet 2018
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
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An epigenetic biomarker of aging for lifespan and healthspan.
Morgan E Levine, Ake T Lu, Austin Quach, Brian H Chen, Themistocles L Assimes, Stefania Bandinelli, Lifang Hou, Andrea A Baccarelli, James D Stewart, Yun Li,[...]. Aging (Albany NY) 2018
Morgan E Levine, Ake T Lu, Austin Quach, Brian H Chen, Themistocles L Assimes, Stefania Bandinelli, Lifang Hou, Andrea A Baccarelli, James D Stewart, Yun Li,[...]. Aging (Albany NY) 2018
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DNA methylation arrays as surrogate measures of cell mixture distribution.
Eugene Andres Houseman, William P Accomando, Devin C Koestler, Brock C Christensen, Carmen J Marsit, Heather H Nelson, John K Wiencke, Karl T Kelsey. BMC Bioinformatics 2012
Eugene Andres Houseman, William P Accomando, Devin C Koestler, Brock C Christensen, Carmen J Marsit, Heather H Nelson, John K Wiencke, Karl T Kelsey. BMC Bioinformatics 2012
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Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context.
Brock C Christensen, E Andres Houseman, Carmen J Marsit, Shichun Zheng, Margaret R Wrensch, Joseph L Wiemels, Heather H Nelson, Margaret R Karagas, James F Padbury, Raphael Bueno,[...]. PLoS Genet 2009
Brock C Christensen, E Andres Houseman, Carmen J Marsit, Shichun Zheng, Margaret R Wrensch, Joseph L Wiemels, Heather H Nelson, Margaret R Karagas, James F Padbury, Raphael Bueno,[...]. PLoS Genet 2009
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DNA methylation aging clocks: challenges and recommendations.
Christopher G Bell, Robert Lowe, Peter D Adams, Andrea A Baccarelli, Stephan Beck, Jordana T Bell, Brock C Christensen, Vadim N Gladyshev, Bastiaan T Heijmans, Steve Horvath,[...]. Genome Biol 2019
Christopher G Bell, Robert Lowe, Peter D Adams, Andrea A Baccarelli, Stephan Beck, Jordana T Bell, Brock C Christensen, Vadim N Gladyshev, Bastiaan T Heijmans, Steve Horvath,[...]. Genome Biol 2019
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DNA methylation GrimAge strongly predicts lifespan and healthspan.
Ake T Lu, Austin Quach, James G Wilson, Alex P Reiner, Abraham Aviv, Kenneth Raj, Lifang Hou, Andrea A Baccarelli, Yun Li, James D Stewart,[...]. Aging (Albany NY) 2019
Ake T Lu, Austin Quach, James G Wilson, Alex P Reiner, Abraham Aviv, Kenneth Raj, Lifang Hou, Andrea A Baccarelli, Yun Li, James D Stewart,[...]. Aging (Albany NY) 2019
8
Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
Carola Ingrid Weidner, Qiong Lin, Carmen Maike Koch, Lewin Eisele, Fabian Beier, Patrick Ziegler, Dirk Olaf Bauerschlag, Karl-Heinz Jöckel, Raimund Erbel, Thomas Walter Mühleisen,[...]. Genome Biol 2014
Carola Ingrid Weidner, Qiong Lin, Carmen Maike Koch, Lewin Eisele, Fabian Beier, Patrick Ziegler, Dirk Olaf Bauerschlag, Karl-Heinz Jöckel, Raimund Erbel, Thomas Walter Mühleisen,[...]. Genome Biol 2014
8
Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays.
Martin J Aryee, Andrew E Jaffe, Hector Corrada-Bravo, Christine Ladd-Acosta, Andrew P Feinberg, Kasper D Hansen, Rafael A Irizarry. Bioinformatics 2014
Martin J Aryee, Andrew E Jaffe, Hector Corrada-Bravo, Christine Ladd-Acosta, Andrew P Feinberg, Kasper D Hansen, Rafael A Irizarry. Bioinformatics 2014
8
Epigenetic Mechanisms of Longevity and Aging.
Payel Sen, Parisha P Shah, Raffaella Nativio, Shelley L Berger. Cell 2016
Payel Sen, Parisha P Shah, Raffaella Nativio, Shelley L Berger. Cell 2016
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DNA methylation-based measures of biological age: meta-analysis predicting time to death.
Brian H Chen, Riccardo E Marioni, Elena Colicino, Marjolein J Peters, Cavin K Ward-Caviness, Pei-Chien Tsai, Nicholas S Roetker, Allan C Just, Ellen W Demerath, Weihua Guan,[...]. Aging (Albany NY) 2016
Brian H Chen, Riccardo E Marioni, Elena Colicino, Marjolein J Peters, Cavin K Ward-Caviness, Pei-Chien Tsai, Nicholas S Roetker, Allan C Just, Ellen W Demerath, Weihua Guan,[...]. Aging (Albany NY) 2016
7
Epigenetics and the environment: emerging patterns and implications.
Robert Feil, Mario F Fraga. Nat Rev Genet 2012
Robert Feil, Mario F Fraga. Nat Rev Genet 2012
7
The epigenetic basis of twin discordance in age-related diseases.
Pernille Poulsen, Manel Esteller, Allan Vaag, Mario F Fraga. Pediatr Res 2007
Pernille Poulsen, Manel Esteller, Allan Vaag, Mario F Fraga. Pediatr Res 2007
6
DNA methylation profiles in monozygotic and dizygotic twins.
Zachary A Kaminsky, Thomas Tang, Sun-Chong Wang, Carolyn Ptak, Gabriel H T Oh, Albert H C Wong, Laura A Feldcamp, Carl Virtanen, Jonas Halfvarson, Curt Tysk,[...]. Nat Genet 2009
Zachary A Kaminsky, Thomas Tang, Sun-Chong Wang, Carolyn Ptak, Gabriel H T Oh, Albert H C Wong, Laura A Feldcamp, Carl Virtanen, Jonas Halfvarson, Curt Tysk,[...]. Nat Genet 2009
6
Epigenetics of discordant monozygotic twins: implications for disease.
Juan E Castillo-Fernandez, Tim D Spector, Jordana T Bell. Genome Med 2014
Juan E Castillo-Fernandez, Tim D Spector, Jordana T Bell. Genome Med 2014
6
Distinct DNA methylomes of newborns and centenarians.
Holger Heyn, Ning Li, Humberto J Ferreira, Sebastian Moran, David G Pisano, Antonio Gomez, Javier Diez, Jose V Sanchez-Mut, Fernando Setien, F Javier Carmona,[...]. Proc Natl Acad Sci U S A 2012
Holger Heyn, Ning Li, Humberto J Ferreira, Sebastian Moran, David G Pisano, Antonio Gomez, Javier Diez, Jose V Sanchez-Mut, Fernando Setien, F Javier Carmona,[...]. Proc Natl Acad Sci U S A 2012
6
Charting a dynamic DNA methylation landscape of the human genome.
Michael J Ziller, Hongcang Gu, Fabian Müller, Julie Donaghey, Linus T-Y Tsai, Oliver Kohlbacher, Philip L De Jager, Evan D Rosen, David A Bennett, Bradley E Bernstein,[...]. Nature 2013
Michael J Ziller, Hongcang Gu, Fabian Müller, Julie Donaghey, Linus T-Y Tsai, Oliver Kohlbacher, Philip L De Jager, Evan D Rosen, David A Bennett, Bradley E Bernstein,[...]. Nature 2013
6
DNA methylation age of blood predicts all-cause mortality in later life.
Riccardo E Marioni, Sonia Shah, Allan F McRae, Brian H Chen, Elena Colicino, Sarah E Harris, Jude Gibson, Anjali K Henders, Paul Redmond, Simon R Cox,[...]. Genome Biol 2015
Riccardo E Marioni, Sonia Shah, Allan F McRae, Brian H Chen, Elena Colicino, Sarah E Harris, Jude Gibson, Anjali K Henders, Paul Redmond, Simon R Cox,[...]. Genome Biol 2015
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Regulation of chromatin by histone modifications.
Andrew J Bannister, Tony Kouzarides. Cell Res 2011
Andrew J Bannister, Tony Kouzarides. Cell Res 2011
6
limma powers differential expression analyses for RNA-sequencing and microarray studies.
Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth. Nucleic Acids Res 2015
Matthew E Ritchie, Belinda Phipson, Di Wu, Yifang Hu, Charity W Law, Wei Shi, Gordon K Smyth. Nucleic Acids Res 2015
6
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals.
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
Rudolf Jaenisch, Adrian Bird. Nat Genet 2003
6
Epigenetic predictor of age.
Sven Bocklandt, Wen Lin, Mary E Sehl, Francisco J Sánchez, Janet S Sinsheimer, Steve Horvath, Eric Vilain. PLoS One 2011
Sven Bocklandt, Wen Lin, Mary E Sehl, Francisco J Sánchez, Janet S Sinsheimer, Steve Horvath, Eric Vilain. PLoS One 2011
6
Persistent epigenetic differences associated with prenatal exposure to famine in humans.
Bastiaan T Heijmans, Elmar W Tobi, Aryeh D Stein, Hein Putter, Gerard J Blauw, Ezra S Susser, P Eline Slagboom, L H Lumey. Proc Natl Acad Sci U S A 2008
Bastiaan T Heijmans, Elmar W Tobi, Aryeh D Stein, Hein Putter, Gerard J Blauw, Ezra S Susser, P Eline Slagboom, L H Lumey. Proc Natl Acad Sci U S A 2008
6
Epigenetic drift in the aging genome: a ten-year follow-up in an elderly twin cohort.
Qihua Tan, Bastiaan T Heijmans, Jacob V B Hjelmborg, Mette Soerensen, Kaare Christensen, Lene Christiansen. Int J Epidemiol 2016
Qihua Tan, Bastiaan T Heijmans, Jacob V B Hjelmborg, Mette Soerensen, Kaare Christensen, Lene Christiansen. Int J Epidemiol 2016
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DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative.
Morgan E Levine, H Dean Hosgood, Brian Chen, Devin Absher, Themistocles Assimes, Steve Horvath. Aging (Albany NY) 2015
Morgan E Levine, H Dean Hosgood, Brian Chen, Devin Absher, Themistocles Assimes, Steve Horvath. Aging (Albany NY) 2015
5
Epigenetic clock analysis of diet, exercise, education, and lifestyle factors.
Austin Quach, Morgan E Levine, Toshiko Tanaka, Ake T Lu, Brian H Chen, Luigi Ferrucci, Beate Ritz, Stefania Bandinelli, Marian L Neuhouser, Jeannette M Beasley,[...]. Aging (Albany NY) 2017
Austin Quach, Morgan E Levine, Toshiko Tanaka, Ake T Lu, Brian H Chen, Luigi Ferrucci, Beate Ritz, Stefania Bandinelli, Marian L Neuhouser, Jeannette M Beasley,[...]. Aging (Albany NY) 2017
5
Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.
Simone Wahl, Alexander Drong, Benjamin Lehne, Marie Loh, William R Scott, Sonja Kunze, Pei-Chien Tsai, Janina S Ried, Weihua Zhang, Youwen Yang,[...]. Nature 2017
Simone Wahl, Alexander Drong, Benjamin Lehne, Marie Loh, William R Scott, Sonja Kunze, Pei-Chien Tsai, Janina S Ried, Weihua Zhang, Youwen Yang,[...]. Nature 2017
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An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Steve Horvath, Michael Gurven, Morgan E Levine, Benjamin C Trumble, Hillard Kaplan, Hooman Allayee, Beate R Ritz, Brian Chen, Ake T Lu, Tammy M Rickabaugh,[...]. Genome Biol 2016
Steve Horvath, Michael Gurven, Morgan E Levine, Benjamin C Trumble, Hillard Kaplan, Hooman Allayee, Beate R Ritz, Brian Chen, Ake T Lu, Tammy M Rickabaugh,[...]. Genome Biol 2016
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5
Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility.
Lovisa E Reinius, Nathalie Acevedo, Maaike Joerink, Göran Pershagen, Sven-Erik Dahlén, Dario Greco, Cilla Söderhäll, Annika Scheynius, Juha Kere. PLoS One 2012
Lovisa E Reinius, Nathalie Acevedo, Maaike Joerink, Göran Pershagen, Sven-Erik Dahlén, Dario Greco, Cilla Söderhäll, Annika Scheynius, Juha Kere. PLoS One 2012
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Functions of DNA methylation: islands, start sites, gene bodies and beyond.
Peter A Jones. Nat Rev Genet 2012
Peter A Jones. Nat Rev Genet 2012
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5
5
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Andrew E Teschendorff, Usha Menon, Aleksandra Gentry-Maharaj, Susan J Ramus, Daniel J Weisenberger, Hui Shen, Mihaela Campan, Houtan Noushmehr, Christopher G Bell, A Peter Maxwell,[...]. Genome Res 2010
Andrew E Teschendorff, Usha Menon, Aleksandra Gentry-Maharaj, Susan J Ramus, Daniel J Weisenberger, Hui Shen, Mihaela Campan, Houtan Noushmehr, Christopher G Bell, A Peter Maxwell,[...]. Genome Res 2010
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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains.
Vardhman K Rakyan, Thomas A Down, Siarhei Maslau, Toby Andrew, Tsun-Po Yang, Huriya Beyan, Pamela Whittaker, Owen T McCann, Sarah Finer, Ana M Valdes,[...]. Genome Res 2010
Vardhman K Rakyan, Thomas A Down, Siarhei Maslau, Toby Andrew, Tsun-Po Yang, Huriya Beyan, Pamela Whittaker, Owen T McCann, Sarah Finer, Ana M Valdes,[...]. Genome Res 2010
5
Integrative analysis of 111 reference human epigenomes.
Anshul Kundaje, Wouter Meuleman, Jason Ernst, Misha Bilenky, Angela Yen, Alireza Heravi-Moussavi, Pouya Kheradpour, Zhizhuo Zhang, Jianrong Wang, Michael J Ziller,[...]. Nature 2015
Anshul Kundaje, Wouter Meuleman, Jason Ernst, Misha Bilenky, Angela Yen, Alireza Heravi-Moussavi, Pouya Kheradpour, Zhizhuo Zhang, Jianrong Wang, Michael J Ziller,[...]. Nature 2015
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Continuous Aging of the Human DNA Methylome Throughout the Human Lifespan.
Asa Johansson, Stefan Enroth, Ulf Gyllensten. PLoS One 2013
Asa Johansson, Stefan Enroth, Ulf Gyllensten. PLoS One 2013
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Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms.
Roderick C Slieker, Maarten van Iterson, René Luijk, Marian Beekman, Daria V Zhernakova, Matthijs H Moed, Hailiang Mei, Michiel van Galen, Patrick Deelen, Marc Jan Bonder,[...]. Genome Biol 2016
Roderick C Slieker, Maarten van Iterson, René Luijk, Marian Beekman, Daria V Zhernakova, Matthijs H Moed, Hailiang Mei, Michiel van Galen, Patrick Deelen, Marc Jan Bonder,[...]. Genome Biol 2016
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DNA methylation and healthy human aging.
Meaghan J Jones, Sarah J Goodman, Michael S Kobor. Aging Cell 2015
Meaghan J Jones, Sarah J Goodman, Michael S Kobor. Aging Cell 2015
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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.
Jordana T Bell, Pei-Chien Tsai, Tsun-Po Yang, Ruth Pidsley, James Nisbet, Daniel Glass, Massimo Mangino, Guangju Zhai, Feng Zhang, Ana Valdes,[...]. PLoS Genet 2012
Jordana T Bell, Pei-Chien Tsai, Tsun-Po Yang, Ruth Pidsley, James Nisbet, Daniel Glass, Massimo Mangino, Guangju Zhai, Feng Zhang, Ana Valdes,[...]. PLoS Genet 2012
5
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.