Pär Steneberg, Nir Rubins, Reut Bartoov-Shifman, Michael D Walker, Helena Edlund. Cell Metab 2005
Times Cited: 326
Times Cited: 326
Times Cited
Times Co-cited
Similarity
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
Yasuaki Itoh, Yuji Kawamata, Masataka Harada, Makoto Kobayashi, Ryo Fujii, Shoji Fukusumi, Kazuhiro Ogi, Masaki Hosoya, Yasuhiro Tanaka, Hiroshi Uejima,[...]. Nature 2003
Yasuaki Itoh, Yuji Kawamata, Masataka Harada, Makoto Kobayashi, Ryo Fujii, Shoji Fukusumi, Kazuhiro Ogi, Masaki Hosoya, Yasuhiro Tanaka, Hiroshi Uejima,[...]. Nature 2003
65
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids.
Celia P Briscoe, Mohammad Tadayyon, John L Andrews, William G Benson, Jon K Chambers, Michelle M Eilert, Catherine Ellis, Nabil A Elshourbagy, Aaron S Goetz, Dana T Minnick,[...]. J Biol Chem 2003
Celia P Briscoe, Mohammad Tadayyon, John L Andrews, William G Benson, Jon K Chambers, Michelle M Eilert, Catherine Ellis, Nabil A Elshourbagy, Aaron S Goetz, Dana T Minnick,[...]. J Biol Chem 2003
52
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion.
Sara Edfalk, Pär Steneberg, Helena Edlund. Diabetes 2008
Sara Edfalk, Pär Steneberg, Helena Edlund. Diabetes 2008
36
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects.
Da Young Oh, Saswata Talukdar, Eun Ju Bae, Takeshi Imamura, Hidetaka Morinaga, WuQiang Fan, Pingping Li, Wendell J Lu, Steven M Watkins, Jerrold M Olefsky. Cell 2010
Da Young Oh, Saswata Talukdar, Eun Ju Bae, Takeshi Imamura, Hidetaka Morinaga, WuQiang Fan, Pingping Li, Wendell J Lu, Steven M Watkins, Jerrold M Olefsky. Cell 2010
34
Overexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.
Kae Nagasumi, Ritsuko Esaki, Kimihiko Iwachidow, Yoshitaka Yasuhara, Kazuhiro Ogi, Hideyuki Tanaka, Mitsugu Nakata, Takashi Yano, Kozo Shimakawa, Shigehisa Taketomi,[...]. Diabetes 2009
Kae Nagasumi, Ritsuko Esaki, Kimihiko Iwachidow, Yoshitaka Yasuhara, Kazuhiro Ogi, Hideyuki Tanaka, Mitsugu Nakata, Takashi Yano, Kozo Shimakawa, Shigehisa Taketomi,[...]. Diabetes 2009
30
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
Akira Hirasawa, Keiko Tsumaya, Takeo Awaji, Susumu Katsuma, Tetsuya Adachi, Masateru Yamada, Yukihiko Sugimoto, Shunichi Miyazaki, Gozoh Tsujimoto. Nat Med 2005
30
GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo.
Martin G Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L Jetton, Jian Luo, Daniel C-H Lin, Vincent Poitout. Diabetes 2007
Martin G Latour, Thierry Alquier, Elizabeth Oseid, Caroline Tremblay, Thomas L Jetton, Jian Luo, Daniel C-H Lin, Vincent Poitout. Diabetes 2007
29
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.
Atsuhiko Ichimura, Akira Hirasawa, Odile Poulain-Godefroy, Amélie Bonnefond, Takafumi Hara, Loïc Yengo, Ikuo Kimura, Audrey Leloire, Ning Liu, Keiko Iida,[...]. Nature 2012
Atsuhiko Ichimura, Akira Hirasawa, Odile Poulain-Godefroy, Amélie Bonnefond, Takafumi Hara, Loïc Yengo, Ikuo Kimura, Audrey Leloire, Ning Liu, Keiko Iida,[...]. Nature 2012
28
The fatty acid receptor GPR40 plays a role in insulin secretion in vivo after high-fat feeding.
Melkam Kebede, Thierry Alquier, Martin G Latour, Meriem Semache, Caroline Tremblay, Vincent Poitout. Diabetes 2008
Melkam Kebede, Thierry Alquier, Martin G Latour, Meriem Semache, Caroline Tremblay, Vincent Poitout. Diabetes 2008
27
Lack of FFAR1/GPR40 does not protect mice from high-fat diet-induced metabolic disease.
Hong Lan, Lizbeth M Hoos, Li Liu, Glen Tetzloff, Weiwen Hu, Susan J Abbondanzo, Galya Vassileva, Eric L Gustafson, Joseph A Hedrick, Harry R Davis. Diabetes 2008
Hong Lan, Lizbeth M Hoos, Li Liu, Glen Tetzloff, Weiwen Hu, Susan J Abbondanzo, Galya Vassileva, Eric L Gustafson, Joseph A Hedrick, Harry R Davis. Diabetes 2008
25
Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release.
Ken Fujiwara, Fumihiko Maekawa, Toshihiko Yada. Am J Physiol Endocrinol Metab 2005
Ken Fujiwara, Fumihiko Maekawa, Toshihiko Yada. Am J Physiol Endocrinol Metab 2005
23
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Andrew J Brown, Susan M Goldsworthy, Ashley A Barnes, Michelle M Eilert, Lili Tcheang, Dion Daniels, Alison I Muir, Mark J Wigglesworth, Ian Kinghorn, Neil J Fraser,[...]. J Biol Chem 2003
Andrew J Brown, Susan M Goldsworthy, Ashley A Barnes, Michelle M Eilert, Lili Tcheang, Dion Daniels, Alison I Muir, Mark J Wigglesworth, Ian Kinghorn, Neil J Fraser,[...]. J Biol Chem 2003
23
The G-protein-coupled receptor GPR40 directly mediates long-chain fatty acid-induced secretion of cholecystokinin.
Alice P Liou, Xinping Lu, Yoshitatsu Sei, Xilin Zhao, Susanne Pechhold, Ricardo J Carrero, Helen E Raybould, Stephen Wank. Gastroenterology 2011
Alice P Liou, Xinping Lu, Yoshitatsu Sei, Xilin Zhao, Susanne Pechhold, Ricardo J Carrero, Helen E Raybould, Stephen Wank. Gastroenterology 2011
22
TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial.
Charles F Burant, Prabhakar Viswanathan, John Marcinak, Charlie Cao, Majid Vakilynejad, Benhuai Xie, Eckhard Leifke. Lancet 2012
Charles F Burant, Prabhakar Viswanathan, John Marcinak, Charlie Cao, Majid Vakilynejad, Benhuai Xie, Eckhard Leifke. Lancet 2012
21
FFAR1 is involved in both the acute and chronic effects of palmitate on insulin secretion.
Hjalti Kristinsson, David M Smith, Peter Bergsten, Ernest Sargsyan. Endocrinology 2013
Hjalti Kristinsson, David M Smith, Peter Bergsten, Ernest Sargsyan. Endocrinology 2013
34
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Celia P Briscoe, Andrew J Peat, Stephen C McKeown, David F Corbett, Aaron S Goetz, Thomas R Littleton, David C McCoy, Terry P Kenakin, John L Andrews, Carina Ammala,[...]. Br J Pharmacol 2006
Celia P Briscoe, Andrew J Peat, Stephen C McKeown, David F Corbett, Aaron S Goetz, Thomas R Littleton, David C McCoy, Terry P Kenakin, John L Andrews, Carina Ammala,[...]. Br J Pharmacol 2006
21
Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes.
Cong Tang, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gröne, Sorin Tunaru, Stefan Offermanns. Nat Med 2015
Cong Tang, Kashan Ahmed, Andreas Gille, Shun Lu, Hermann-Josef Gröne, Sorin Tunaru, Stefan Offermanns. Nat Med 2015
19
Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids.
Hongfei Ge, Xiaofan Li, Jennifer Weiszmann, Ping Wang, Helene Baribault, Jin-Long Chen, Hui Tian, Yang Li. Endocrinology 2008
Hongfei Ge, Xiaofan Li, Jennifer Weiszmann, Ping Wang, Helene Baribault, Jin-Long Chen, Hui Tian, Yang Li. Endocrinology 2008
18
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.
Emmanuel Le Poul, Cecile Loison, Sofie Struyf, Jean-Yves Springael, Vincent Lannoy, Marie-Eve Decobecq, Stephane Brezillon, Vincent Dupriez, Gilbert Vassart, Jo Van Damme,[...]. J Biol Chem 2003
Emmanuel Le Poul, Cecile Loison, Sofie Struyf, Jean-Yves Springael, Vincent Lannoy, Marie-Eve Decobecq, Stephane Brezillon, Vincent Dupriez, Gilbert Vassart, Jo Van Damme,[...]. J Biol Chem 2003
18
The regulation of adipogenesis through GPR120.
Chizu Gotoh, Yeon-Hee Hong, Tomoyo Iga, Daisuke Hishikawa, Yasuki Suzuki, Sang-Houn Song, Ki-Choon Choi, Tetsuya Adachi, Akira Hirasawa, Gozoh Tsujimoto,[...]. Biochem Biophys Res Commun 2007
Chizu Gotoh, Yeon-Hee Hong, Tomoyo Iga, Daisuke Hishikawa, Yasuki Suzuki, Sang-Houn Song, Ki-Choon Choi, Tetsuya Adachi, Akira Hirasawa, Gozoh Tsujimoto,[...]. Biochem Biophys Res Commun 2007
18
A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents.
Jian Luo, Gayathri Swaminath, Sean P Brown, Jane Zhang, Qi Guo, Michael Chen, Kathy Nguyen, Thanhvien Tran, Lynn Miao, Paul J Dransfield,[...]. PLoS One 2012
Jian Luo, Gayathri Swaminath, Sean P Brown, Jane Zhang, Qi Guo, Michael Chen, Kathy Nguyen, Thanhvien Tran, Lynn Miao, Paul J Dransfield,[...]. PLoS One 2012
17
GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo.
Maria Hauge, Marie A Vestmar, Anna S Husted, Jeppe P Ekberg, Michael J Wright, Jerry Di Salvo, Adam B Weinglass, Maja S Engelstoft, Andreas N Madsen, Michael Lückmann,[...]. Mol Metab 2014
Maria Hauge, Marie A Vestmar, Anna S Husted, Jeppe P Ekberg, Michael J Wright, Jerry Di Salvo, Adam B Weinglass, Maja S Engelstoft, Andreas N Madsen, Michael Lückmann,[...]. Mol Metab 2014
17
Role of GPR40 in fatty acid action on the beta cell line INS-1E.
Hagit Shapiro, Sigal Shachar, Israel Sekler, Michal Hershfinkel, Michael D Walker. Biochem Biophys Res Commun 2005
Hagit Shapiro, Sigal Shachar, Israel Sekler, Michal Hershfinkel, Michael D Walker. Biochem Biophys Res Commun 2005
17
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs.
Knut Kotarsky, Niclas E Nilsson, Erik Flodgren, Christer Owman, Björn Olde. Biochem Biophys Res Commun 2003
Knut Kotarsky, Niclas E Nilsson, Erik Flodgren, Christer Owman, Björn Olde. Biochem Biophys Res Commun 2003
17
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2.
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
Gwen Tolhurst, Helen Heffron, Yu Shan Lam, Helen E Parker, Abdella M Habib, Eleftheria Diakogiannaki, Jennifer Cameron, Johannes Grosse, Frank Reimann, Fiona M Gribble. Diabetes 2012
17
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.
Da Young Oh, Evelyn Walenta, Taro E Akiyama, William S Lagakos, Denise Lackey, Ariane R Pessentheiner, Roman Sasik, Nasun Hah, Tyler J Chi, Jason M Cox,[...]. Nat Med 2014
Da Young Oh, Evelyn Walenta, Taro E Akiyama, William S Lagakos, Denise Lackey, Ariane R Pessentheiner, Roman Sasik, Nasun Hah, Tyler J Chi, Jason M Cox,[...]. Nat Med 2014
17
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from beta-cells through activation of GPR40.
Susanne Schnell, Michael Schaefer, Christof Schöfl. Mol Cell Endocrinol 2007
Susanne Schnell, Michael Schaefer, Christof Schöfl. Mol Cell Endocrinol 2007
16
TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.
Yoshiyuki Tsujihata, Ryo Ito, Masami Suzuki, Ayako Harada, Nobuyuki Negoro, Tsuneo Yasuma, Yu Momose, Koji Takeuchi. J Pharmacol Exp Ther 2011
Yoshiyuki Tsujihata, Ryo Ito, Masami Suzuki, Ayako Harada, Nobuyuki Negoro, Tsuneo Yasuma, Yu Momose, Koji Takeuchi. J Pharmacol Exp Ther 2011
16
Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist.
Nobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami, Masahiro Ito, Masami Suzuki, Yoshiyuki Tsujihata, Ryo Ito, Ayako Harada, Koji Takeuchi, Nobuhiro Suzuki,[...]. ACS Med Chem Lett 2010
Nobuyuki Negoro, Shinobu Sasaki, Satoshi Mikami, Masahiro Ito, Masami Suzuki, Yoshiyuki Tsujihata, Ryo Ito, Ayako Harada, Koji Takeuchi, Nobuhiro Suzuki,[...]. ACS Med Chem Lett 2010
16
Safety, tolerability, pharmacokinetics, and pharmacodynamic properties of the GPR40 agonist TAK-875: results from a double-blind, placebo-controlled single oral dose rising study in healthy volunteers.
Himanshu Naik, Majid Vakilynejad, Jingtao Wu, Prabhakar Viswanathan, Nobuhito Dote, Tomoaki Higuchi, Eckhard Leifke. J Clin Pharmacol 2012
Himanshu Naik, Majid Vakilynejad, Jingtao Wu, Prabhakar Viswanathan, Nobuhito Dote, Tomoaki Higuchi, Eckhard Leifke. J Clin Pharmacol 2012
19
A multiple-ascending-dose study to evaluate safety, pharmacokinetics, and pharmacodynamics of a novel GPR40 agonist, TAK-875, in subjects with type 2 diabetes.
E Leifke, H Naik, J Wu, P Viswanathan, D Demanno, M Kipnes, M Vakilynejad. Clin Pharmacol Ther 2012
E Leifke, H Naik, J Wu, P Viswanathan, D Demanno, M Kipnes, M Vakilynejad. Clin Pharmacol Ther 2012
19
Taste preference for fatty acids is mediated by GPR40 and GPR120.
Cristina Cartoni, Keiko Yasumatsu, Tadahiro Ohkuri, Noriatsu Shigemura, Ryusuke Yoshida, Nicolas Godinot, Johannes le Coutre, Yuzo Ninomiya, Sami Damak. J Neurosci 2010
Cristina Cartoni, Keiko Yasumatsu, Tadahiro Ohkuri, Noriatsu Shigemura, Ryusuke Yoshida, Nicolas Godinot, Johannes le Coutre, Yuzo Ninomiya, Sami Damak. J Neurosci 2010
15
Efficacy and safety of fasiglifam (TAK-875), a G protein-coupled receptor 40 agonist, in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise: a randomized, double-blind, placebo-controlled, phase III trial.
K Kaku, K Enya, R Nakaya, T Ohira, R Matsuno. Diabetes Obes Metab 2015
K Kaku, K Enya, R Nakaya, T Ohira, R Matsuno. Diabetes Obes Metab 2015
15
The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?
Arturo D Mancini, Vincent Poitout. Trends Endocrinol Metab 2013
Arturo D Mancini, Vincent Poitout. Trends Endocrinol Metab 2013
14
GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes.
T Araki, M Hirayama, S Hiroi, K Kaku. Diabetes Obes Metab 2012
T Araki, M Hirayama, S Hiroi, K Kaku. Diabetes Obes Metab 2012
17
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43.
Kendle M Maslowski, Angelica T Vieira, Aylwin Ng, Jan Kranich, Frederic Sierro, Di Yu, Heidi C Schilter, Michael S Rolph, Fabienne Mackay, David Artis,[...]. Nature 2009
Kendle M Maslowski, Angelica T Vieira, Aylwin Ng, Jan Kranich, Frederic Sierro, Di Yu, Heidi C Schilter, Michael S Rolph, Fabienne Mackay, David Artis,[...]. Nature 2009
14
The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43.
Ikuo Kimura, Kentaro Ozawa, Daisuke Inoue, Takeshi Imamura, Kumi Kimura, Takeshi Maeda, Kazuya Terasawa, Daiji Kashihara, Kanako Hirano, Taeko Tani,[...]. Nat Commun 2013
Ikuo Kimura, Kentaro Ozawa, Daisuke Inoue, Takeshi Imamura, Kumi Kimura, Takeshi Maeda, Kazuya Terasawa, Daiji Kashihara, Kanako Hirano, Taeko Tani,[...]. Nat Commun 2013
14
Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids.
Niclas E Nilsson, Knut Kotarsky, Christer Owman, Björn Olde. Biochem Biophys Res Commun 2003
Niclas E Nilsson, Knut Kotarsky, Christer Owman, Björn Olde. Biochem Biophys Res Commun 2003
14
Reevaluation of fatty acid receptor 1 as a drug target for the stimulation of insulin secretion in humans.
Robert Wagner, Gabriele Kaiser, Felicia Gerst, Elisabeth Christiansen, Maria E Due-Hansen, Manuel Grundmann, Fausto Machicao, Andreas Peter, Evi Kostenis, Trond Ulven,[...]. Diabetes 2013
Robert Wagner, Gabriele Kaiser, Felicia Gerst, Elisabeth Christiansen, Maria E Due-Hansen, Manuel Grundmann, Fausto Machicao, Andreas Peter, Evi Kostenis, Trond Ulven,[...]. Diabetes 2013
23
G protein-coupled receptor (GPR)40-dependent potentiation of insulin secretion in mouse islets is mediated by protein kinase D1.
M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, E N Olson, M Prentki, T Biden, P E MacDonald,[...]. Diabetologia 2012
M Ferdaoussi, V Bergeron, B Zarrouki, J Kolic, J Cantley, J Fielitz, E N Olson, M Prentki, T Biden, P E MacDonald,[...]. Diabetologia 2012
13
Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells.
H E Parker, A M Habib, G J Rogers, F M Gribble, F Reimann. Diabetologia 2009
H E Parker, A M Habib, G J Rogers, F M Gribble, F Reimann. Diabetologia 2009
13
Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1.
Yumei Xiong, Gayathri Swaminath, Qiong Cao, Li Yang, Qi Guo, Heather Salomonis, Jenny Lu, Jonathan B Houze, Paul J Dransfield, Yingcai Wang,[...]. Mol Cell Endocrinol 2013
Yumei Xiong, Gayathri Swaminath, Qiong Cao, Li Yang, Qi Guo, Heather Salomonis, Jenny Lu, Jonathan B Houze, Paul J Dransfield, Yingcai Wang,[...]. Mol Cell Endocrinol 2013
18
Recent developments in the discovery of FFA1 receptor agonists as novel oral treatment for type 2 diabetes mellitus.
Elisabeth Defossa, Michael Wagner. Bioorg Med Chem Lett 2014
Elisabeth Defossa, Michael Wagner. Bioorg Med Chem Lett 2014
16
GPR40 agonists for the treatment of type 2 diabetes: life after 'TAKing' a hit.
A D Mancini, V Poitout. Diabetes Obes Metab 2015
A D Mancini, V Poitout. Diabetes Obes Metab 2015
18
Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43.
Yeon-Hee Hong, Yukihiko Nishimura, Daisuke Hishikawa, Hiroaki Tsuzuki, Hisae Miyahara, Chizu Gotoh, Ki-Choon Choi, Dan Dan Feng, Chen Chen, Hong-Gu Lee,[...]. Endocrinology 2005
Yeon-Hee Hong, Yukihiko Nishimura, Daisuke Hishikawa, Hiroaki Tsuzuki, Hisae Miyahara, Chizu Gotoh, Ki-Choon Choi, Dan Dan Feng, Chen Chen, Hong-Gu Lee,[...]. Endocrinology 2005
12
Involvement of the long-chain fatty acid receptor GPR40 as a novel pain regulatory system.
Kazuo Nakamoto, Takashi Nishinaka, Kengo Matsumoto, Fumiyo Kasuya, Mitsumasa Mankura, Yutaka Koyama, Shogo Tokuyama. Brain Res 2012
Kazuo Nakamoto, Takashi Nishinaka, Kengo Matsumoto, Fumiyo Kasuya, Mitsumasa Mankura, Yutaka Koyama, Shogo Tokuyama. Brain Res 2012
12
Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor.
Daniel C-H Lin, Qi Guo, Jian Luo, Jane Zhang, Kathy Nguyen, Michael Chen, Thanh Tran, Paul J Dransfield, Sean P Brown, Jonathan Houze,[...]. Mol Pharmacol 2012
Daniel C-H Lin, Qi Guo, Jian Luo, Jane Zhang, Kathy Nguyen, Michael Chen, Thanh Tran, Paul J Dransfield, Sean P Brown, Jonathan Houze,[...]. Mol Pharmacol 2012
12
Randomized, double-blind, dose-ranging study of TAK-875, a novel GPR40 agonist, in Japanese patients with inadequately controlled type 2 diabetes.
Kohei Kaku, Takahiro Araki, Ryoji Yoshinaka. Diabetes Care 2013
Kohei Kaku, Takahiro Araki, Ryoji Yoshinaka. Diabetes Care 2013
15
Identification of residues important for agonist recognition and activation in GPR40.
Chi Shing Sum, Irina G Tikhonova, Susanne Neumann, Stanislav Engel, Bruce M Raaka, Stefano Costanzi, Marvin C Gershengorn. J Biol Chem 2007
Chi Shing Sum, Irina G Tikhonova, Susanne Neumann, Stanislav Engel, Bruce M Raaka, Stefano Costanzi, Marvin C Gershengorn. J Biol Chem 2007
12
A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1.
Chiori Yabuki, Hidetoshi Komatsu, Yoshiyuki Tsujihata, Risa Maeda, Ryo Ito, Kae Matsuda-Nagasumi, Kensuke Sakuma, Kazumasa Miyawaki, Naoya Kikuchi, Koji Takeuchi,[...]. PLoS One 2013
Chiori Yabuki, Hidetoshi Komatsu, Yoshiyuki Tsujihata, Risa Maeda, Ryo Ito, Kae Matsuda-Nagasumi, Kensuke Sakuma, Kazumasa Miyawaki, Naoya Kikuchi, Koji Takeuchi,[...]. PLoS One 2013
17
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.