Minghao Jin, Songhua Li, Walid N Moghrabi, Hui Sun, Gabriel H Travis. Cell 2005
Times Cited: 330
Times Cited: 330
Times Cited
Times Co-cited
Similarity
RPE65 is the isomerohydrolase in the retinoid visual cycle.
Gennadiy Moiseyev, Ying Chen, Yusuke Takahashi, Bill X Wu, Jian-Xing Ma. Proc Natl Acad Sci U S A 2005
Gennadiy Moiseyev, Ying Chen, Yusuke Takahashi, Bill X Wu, Jian-Xing Ma. Proc Natl Acad Sci U S A 2005
73
Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.
T Michael Redmond, Eugenia Poliakov, Shirley Yu, Jen-Yue Tsai, Zhongjian Lu, Susan Gentleman. Proc Natl Acad Sci U S A 2005
T Michael Redmond, Eugenia Poliakov, Shirley Yu, Jen-Yue Tsai, Zhongjian Lu, Susan Gentleman. Proc Natl Acad Sci U S A 2005
61
Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.
T M Redmond, S Yu, E Lee, D Bok, D Hamasaki, N Chen, P Goletz, J X Ma, R K Crouch, K Pfeifer. Nat Genet 1998
T M Redmond, S Yu, E Lee, D Bok, D Hamasaki, N Chen, P Goletz, J X Ma, R K Crouch, K Pfeifer. Nat Genet 1998
39
Mutations in RPE65 cause Leber's congenital amaurosis.
F Marlhens, C Bareil, J M Griffoin, E Zrenner, P Amalric, C Eliaou, S Y Liu, E Harris, T M Redmond, B Arnaud,[...]. Nat Genet 1997
F Marlhens, C Bareil, J M Griffoin, E Zrenner, P Amalric, C Eliaou, S Y Liu, E Harris, T M Redmond, B Arnaud,[...]. Nat Genet 1997
24
Effect of gene therapy on visual function in Leber's congenital amaurosis.
James W B Bainbridge, Alexander J Smith, Susie S Barker, Scott Robbie, Robert Henderson, Kamaljit Balaggan, Ananth Viswanathan, Graham E Holder, Andrew Stockman, Nick Tyler,[...]. N Engl J Med 2008
James W B Bainbridge, Alexander J Smith, Susie S Barker, Scott Robbie, Robert Henderson, Kamaljit Balaggan, Ananth Viswanathan, Graham E Holder, Andrew Stockman, Nick Tyler,[...]. N Engl J Med 2008
23
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle.
Philip D Kiser, Marcin Golczak, David T Lodowski, Mark R Chance, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2009
Philip D Kiser, Marcin Golczak, David T Lodowski, Mark R Chance, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2009
23
Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy.
S M Gu, D A Thompson, C R Srikumari, B Lorenz, U Finckh, A Nicoletti, K R Murthy, M Rathmann, G Kumaramanickavel, M J Denton,[...]. Nat Genet 1997
S M Gu, D A Thompson, C R Srikumari, B Lorenz, U Finckh, A Nicoletti, K R Murthy, M Rathmann, G Kumaramanickavel, M J Denton,[...]. Nat Genet 1997
21
Safety and efficacy of gene transfer for Leber's congenital amaurosis.
Albert M Maguire, Francesca Simonelli, Eric A Pierce, Edward N Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen A Marshall, Francesco Testa, Enrico M Surace,[...]. N Engl J Med 2008
Albert M Maguire, Francesca Simonelli, Eric A Pierce, Edward N Pugh, Federico Mingozzi, Jeannette Bennicelli, Sandro Banfi, Kathleen A Marshall, Francesco Testa, Enrico M Surace,[...]. N Engl J Med 2008
21
Chemistry of the retinoid (visual) cycle.
Philip D Kiser, Marcin Golczak, Krzysztof Palczewski. Chem Rev 2014
Philip D Kiser, Marcin Golczak, Krzysztof Palczewski. Chem Rev 2014
20
Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.
Matthew L Batten, Yoshikazu Imanishi, Tadao Maeda, Daniel C Tu, Alexander R Moise, Darin Bronson, Daniel Possin, Russell N Van Gelder, Wolfgang Baehr, Krzysztof Palczewski. J Biol Chem 2004
Matthew L Batten, Yoshikazu Imanishi, Tadao Maeda, Daniel C Tu, Alexander R Moise, Darin Bronson, Daniel Possin, Russell N Van Gelder, Wolfgang Baehr, Krzysztof Palczewski. J Biol Chem 2004
19
Mutations in the RPE65 gene in patients with autosomal recessive retinitis pigmentosa or leber congenital amaurosis.
H Morimura, G A Fishman, S A Grover, A B Fulton, E L Berson, T P Dryja. Proc Natl Acad Sci U S A 1998
H Morimura, G A Fishman, S A Grover, A B Fulton, E L Berson, T P Dryja. Proc Natl Acad Sci U S A 1998
19
Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro.
C P Hamel, E Tsilou, B A Pfeffer, J J Hooks, B Detrick, T M Redmond. J Biol Chem 1993
C P Hamel, E Tsilou, B A Pfeffer, J J Hooks, B Detrick, T M Redmond. J Biol Chem 1993
18
Treatment of leber congenital amaurosis due to RPE65 mutations by ocular subretinal injection of adeno-associated virus gene vector: short-term results of a phase I trial.
William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Artur V Cideciyan, Sharon B Schwartz, Lili Wang, Thomas J Conlon, Sanford L Boye, Terence R Flotte, Barry J Byrne,[...]. Hum Gene Ther 2008
William W Hauswirth, Tomas S Aleman, Shalesh Kaushal, Artur V Cideciyan, Sharon B Schwartz, Lili Wang, Thomas J Conlon, Sanford L Boye, Terence R Flotte, Barry J Byrne,[...]. Hum Gene Ther 2008
16
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
Gabriel H Travis, Marcin Golczak, Alexander R Moise, Krzysztof Palczewski. Annu Rev Pharmacol Toxicol 2007
Gabriel H Travis, Marcin Golczak, Alexander R Moise, Krzysztof Palczewski. Annu Rev Pharmacol Toxicol 2007
15
Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.
Philip D Kiser, Erik R Farquhar, Wuxian Shi, Xuewu Sui, Mark R Chance, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2012
Philip D Kiser, Erik R Farquhar, Wuxian Shi, Xuewu Sui, Mark R Chance, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2012
31
Catalytic mechanism of a retinoid isomerase essential for vertebrate vision.
Philip D Kiser, Jianye Zhang, Mohsen Badiee, Qingjiang Li, Wuxian Shi, Xuewu Sui, Marcin Golczak, Gregory P Tochtrop, Krzysztof Palczewski. Nat Chem Biol 2015
Philip D Kiser, Jianye Zhang, Mohsen Badiee, Qingjiang Li, Wuxian Shi, Xuewu Sui, Marcin Golczak, Gregory P Tochtrop, Krzysztof Palczewski. Nat Chem Biol 2015
31
Visual cycle impairment in cellular retinaldehyde binding protein (CRALBP) knockout mice results in delayed dark adaptation.
J C Saari, M Nawrot, B N Kennedy, G G Garwin, J B Hurley, J Huang, D E Possin, J W Crabb. Neuron 2001
J C Saari, M Nawrot, B N Kennedy, G G Garwin, J B Hurley, J Huang, D E Possin, J W Crabb. Neuron 2001
14
Isomerization and oxidation of vitamin a in cone-dominant retinas: a novel pathway for visual-pigment regeneration in daylight.
Nathan L Mata, Roxana A Radu, Richard C Clemmons, Gabriel H Travis. Neuron 2002
Nathan L Mata, Roxana A Radu, Richard C Clemmons, Gabriel H Travis. Neuron 2002
14
Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle.
Marcin Golczak, Vladimir Kuksa, Tadao Maeda, Alexander R Moise, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2005
Marcin Golczak, Vladimir Kuksa, Tadao Maeda, Alexander R Moise, Krzysztof Palczewski. Proc Natl Acad Sci U S A 2005
14
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
Joanna J Kaylor, Quan Yuan, Jeremy Cook, Shanta Sarfare, Jacob Makshanoff, Anh Miu, Anita Kim, Paul Kim, Samer Habib, C Nathaniel Roybal,[...]. Nat Chem Biol 2013
Joanna J Kaylor, Quan Yuan, Jeremy Cook, Shanta Sarfare, Jacob Makshanoff, Anh Miu, Anita Kim, Paul Kim, Samer Habib, C Nathaniel Roybal,[...]. Nat Chem Biol 2013
17
A dominant mutation in RPE65 identified by whole-exome sequencing causes retinitis pigmentosa with choroidal involvement.
Sara J Bowne, Marian M Humphries, Lori S Sullivan, Paul F Kenna, Lawrence C S Tam, Anna S Kiang, Matthew Campbell, George M Weinstock, Daniel C Koboldt, Li Ding,[...]. Eur J Hum Genet 2011
Sara J Bowne, Marian M Humphries, Lori S Sullivan, Paul F Kenna, Lawrence C S Tam, Anna S Kiang, Matthew Campbell, George M Weinstock, Daniel C Koboldt, Li Ding,[...]. Eur J Hum Genet 2011
14
A membrane receptor for retinol binding protein mediates cellular uptake of vitamin A.
Riki Kawaguchi, Jiamei Yu, Jane Honda, Jane Hu, Julian Whitelegge, Peipei Ping, Patrick Wiita, Dean Bok, Hui Sun. Science 2007
Riki Kawaguchi, Jiamei Yu, Jane Honda, Jane Hu, Julian Whitelegge, Peipei Ping, Patrick Wiita, Dean Bok, Hui Sun. Science 2007
13
Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes.
J C Saari, D L Bredberg. J Biol Chem 1989
J C Saari, D L Bredberg. J Biol Chem 1989
13
13
Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvement.
Artur V Cideciyan, Samuel G Jacobson, William A Beltran, Alexander Sumaroka, Malgorzata Swider, Simone Iwabe, Alejandro J Roman, Melani B Olivares, Sharon B Schwartz, András M Komáromy,[...]. Proc Natl Acad Sci U S A 2013
Artur V Cideciyan, Samuel G Jacobson, William A Beltran, Alexander Sumaroka, Malgorzata Swider, Simone Iwabe, Alejandro J Roman, Melani B Olivares, Sharon B Schwartz, András M Komáromy,[...]. Proc Natl Acad Sci U S A 2013
13
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics.
Artur V Cideciyan, Tomas S Aleman, Sanford L Boye, Sharon B Schwartz, Shalesh Kaushal, Alejandro J Roman, Ji-Jing Pang, Alexander Sumaroka, Elizabeth A M Windsor, James M Wilson,[...]. Proc Natl Acad Sci U S A 2008
Artur V Cideciyan, Tomas S Aleman, Sanford L Boye, Sharon B Schwartz, Shalesh Kaushal, Alejandro J Roman, Ji-Jing Pang, Alexander Sumaroka, Elizabeth A M Windsor, James M Wilson,[...]. Proc Natl Acad Sci U S A 2008
13
Human cone photoreceptor dependence on RPE65 isomerase.
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Elise Heon, Marcin Golczak, William A Beltran, Alexander Sumaroka, Sharon B Schwartz, Alejandro J Roman, Elizabeth A M Windsor,[...]. Proc Natl Acad Sci U S A 2007
Samuel G Jacobson, Tomas S Aleman, Artur V Cideciyan, Elise Heon, Marcin Golczak, William A Beltran, Alexander Sumaroka, Sharon B Schwartz, Alejandro J Roman, Elizabeth A M Windsor,[...]. Proc Natl Acad Sci U S A 2007
13
Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice.
J Weng, N L Mata, S M Azarian, R T Tzekov, D G Birch, G H Travis. Cell 1999
J Weng, N L Mata, S M Azarian, R T Tzekov, D G Birch, G H Travis. Cell 1999
13
12
Importance of membrane structural integrity for RPE65 retinoid isomerization activity.
Marcin Golczak, Philip D Kiser, David T Lodowski, Akiko Maeda, Krzysztof Palczewski. J Biol Chem 2010
Marcin Golczak, Philip D Kiser, David T Lodowski, Akiko Maeda, Krzysztof Palczewski. J Biol Chem 2010
24
The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.
A Wenzel, C E Reme, T P Williams, F Hafezi, C Grimm. J Neurosci 2001
A Wenzel, C E Reme, T P Williams, F Hafezi, C Grimm. J Neurosci 2001
12
RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization.
T Michael Redmond, Eugenia Poliakov, Stephanie Kuo, Preethi Chander, Susan Gentleman. J Biol Chem 2010
T Michael Redmond, Eugenia Poliakov, Stephanie Kuo, Preethi Chander, Susan Gentleman. J Biol Chem 2010
24
Long-term effect of gene therapy on Leber's congenital amaurosis.
James W B Bainbridge, Manjit S Mehat, Venki Sundaram, Scott J Robbie, Susie E Barker, Caterina Ripamonti, Anastasios Georgiadis, Freya M Mowat, Stuart G Beattie, Peter J Gardner,[...]. N Engl J Med 2015
James W B Bainbridge, Manjit S Mehat, Venki Sundaram, Scott J Robbie, Susie E Barker, Caterina Ripamonti, Anastasios Georgiadis, Freya M Mowat, Stuart G Beattie, Peter J Gardner,[...]. N Engl J Med 2015
12
Molecular and biochemical characterization of lecithin retinol acyltransferase.
A Ruiz, A Winston, Y H Lim, B A Gilbert, R R Rando, D Bok. J Biol Chem 1999
A Ruiz, A Winston, Y H Lim, B A Gilbert, R R Rando, D Bok. J Biol Chem 1999
11
Role of LRAT on the retinoid isomerase activity and membrane association of Rpe65.
Minghao Jin, Quan Yuan, Songhua Li, Gabriel H Travis. J Biol Chem 2007
Minghao Jin, Quan Yuan, Songhua Li, Gabriel H Travis. J Biol Chem 2007
30
Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration.
D A Thompson, P Gyürüs, L L Fleischer, E L Bingham, C L McHenry, E Apfelstedt-Sylla, E Zrenner, B Lorenz, J E Richards, S G Jacobson,[...]. Invest Ophthalmol Vis Sci 2000
D A Thompson, P Gyürüs, L L Fleischer, E L Bingham, C L McHenry, E Apfelstedt-Sylla, E Zrenner, B Lorenz, J E Richards, S G Jacobson,[...]. Invest Ophthalmol Vis Sci 2000
11
Rescue of enzymatic function for disease-associated RPE65 proteins containing various missense mutations in non-active sites.
Songhua Li, Tadahide Izumi, Jane Hu, Heather H Jin, Ahmed-Abdul A Siddiqui, Samuel G Jacobson, Dean Bok, Minghao Jin. J Biol Chem 2014
Songhua Li, Tadahide Izumi, Jane Hu, Heather H Jin, Ahmed-Abdul A Siddiqui, Samuel G Jacobson, Dean Bok, Minghao Jin. J Biol Chem 2014
39
A photic visual cycle of rhodopsin regeneration is dependent on Rgr.
P Chen, W Hao, L Rife, X P Wang, D Shen, J Chen, T Ogden, G B Van Boemel, L Wu, M Yang,[...]. Nat Genet 2001
P Chen, W Hao, L Rife, X P Wang, D Shen, J Chen, T Ogden, G B Van Boemel, L Wu, M Yang,[...]. Nat Genet 2001
11
Identification and characterization of all-trans-retinol dehydrogenase from photoreceptor outer segments, the visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol.
A Rattner, P M Smallwood, J Nathans. J Biol Chem 2000
A Rattner, P M Smallwood, J Nathans. J Biol Chem 2000
11
Leber congenital amaurosis: genes, proteins and disease mechanisms.
Anneke I den Hollander, Ronald Roepman, Robert K Koenekoop, Frans P M Cremers. Prog Retin Eye Res 2008
Anneke I den Hollander, Ronald Roepman, Robert K Koenekoop, Frans P M Cremers. Prog Retin Eye Res 2008
10
Crystal structure of rhodopsin: A G protein-coupled receptor.
K Palczewski, T Kumasaka, T Hori, C A Behnke, H Motoshima, B A Fox, I Le Trong, D C Teller, T Okada, R E Stenkamp,[...]. Science 2000
K Palczewski, T Kumasaka, T Hori, C A Behnke, H Motoshima, B A Fox, I Le Trong, D C Teller, T Okada, R E Stenkamp,[...]. Science 2000
10
Gene therapy restores vision in a canine model of childhood blindness.
G M Acland, G D Aguirre, J Ray, Q Zhang, T S Aleman, A V Cideciyan, S E Pearce-Kelling, V Anand, Y Zeng, A M Maguire,[...]. Nat Genet 2001
G M Acland, G D Aguirre, J Ray, Q Zhang, T S Aleman, A V Cideciyan, S E Pearce-Kelling, V Anand, Y Zeng, A M Maguire,[...]. Nat Genet 2001
10
Retinal degeneration 12 (rd12): a new, spontaneously arising mouse model for human Leber congenital amaurosis (LCA).
Ji-Jing Pang, Bo Chang, Norman L Hawes, Ronald E Hurd, Muriel T Davisson, Jie Li, Syed M Noorwez, Ritu Malhotra, J Hugh McDowell, Shalesh Kaushal,[...]. Mol Vis 2005
Ji-Jing Pang, Bo Chang, Norman L Hawes, Ronald E Hurd, Muriel T Davisson, Jie Li, Syed M Noorwez, Ritu Malhotra, J Hugh McDowell, Shalesh Kaushal,[...]. Mol Vis 2005
10
Fatty acid transport protein 4 (FATP4) prevents light-induced degeneration of cone and rod photoreceptors by inhibiting RPE65 isomerase.
Songhua Li, Jungsoo Lee, Yongdong Zhou, William C Gordon, James M Hill, Nicolas G Bazan, Jeffrey H Miner, Minghao Jin. J Neurosci 2013
Songhua Li, Jungsoo Lee, Yongdong Zhou, William C Gordon, James M Hill, Nicolas G Bazan, Jeffrey H Miner, Minghao Jin. J Neurosci 2013
38
Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane.
Olga Nikolaeva, Yusuke Takahashi, Gennadiy Moiseyev, Jian-Xing Ma. FEBS J 2009
Olga Nikolaeva, Yusuke Takahashi, Gennadiy Moiseyev, Jian-Xing Ma. FEBS J 2009
32
R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal.
Marijana Samardzija, Johannes von Lintig, Naoyuki Tanimoto, Vitus Oberhauser, Markus Thiersch, Charlotte E Remé, Mathias Seeliger, Christian Grimm, Andreas Wenzel. Hum Mol Genet 2008
Marijana Samardzija, Johannes von Lintig, Naoyuki Tanimoto, Vitus Oberhauser, Markus Thiersch, Charlotte E Remé, Mathias Seeliger, Christian Grimm, Andreas Wenzel. Hum Mol Genet 2008
13
CRALBP supports the mammalian retinal visual cycle and cone vision.
Yunlu Xue, Susan Q Shen, Jonathan Jui, Alan C Rupp, Leah C Byrne, Samer Hattar, John G Flannery, Joseph C Corbo, Vladimir J Kefalov. J Clin Invest 2015
Yunlu Xue, Susan Q Shen, Jonathan Jui, Alan C Rupp, Leah C Byrne, Samer Hattar, John G Flannery, Joseph C Corbo, Vladimir J Kefalov. J Clin Invest 2015
14
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.