Arne N Akbar, Jean M Fletcher. Curr Opin Immunol 2005
Times Cited: 145
Times Cited: 145
Times Cited
Times Co-cited
Similarity
Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals.
Naeem Khan, Naseer Shariff, Mark Cobbold, Rachel Bruton, Jenni A Ainsworth, Alan J Sinclair, Laxman Nayak, Paul A H Moss. J Immunol 2002
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Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections.
Janko Nikolich-Zugich. Nat Rev Immunol 2008
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T cell subset-specific susceptibility to aging.
Marta Czesnikiewicz-Guzik, Won-Woo Lee, Dapeng Cui, Yuko Hiruma, David L Lamar, Zhi-Zhang Yang, Joseph G Ouslander, Cornelia M Weyand, Jörg J Goronzy. Clin Immunol 2008
Marta Czesnikiewicz-Guzik, Won-Woo Lee, Dapeng Cui, Yuko Hiruma, David L Lamar, Zhi-Zhang Yang, Joseph G Ouslander, Cornelia M Weyand, Jörg J Goronzy. Clin Immunol 2008
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Inflamm-aging. An evolutionary perspective on immunosenescence.
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
C Franceschi, M Bonafè, S Valensin, F Olivieri, M De Luca, E Ottaviani, G De Benedictis. Ann N Y Acad Sci 2000
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Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?
Arne N Akbar, Sian M Henson. Nat Rev Immunol 2011
Arne N Akbar, Sian M Henson. Nat Rev Immunol 2011
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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.
Andrew W Sylwester, Bridget L Mitchell, John B Edgar, Cara Taormina, Christian Pelte, Franziska Ruchti, Paul R Sleath, Kenneth H Grabstein, Nancy A Hosken, Florian Kern,[...]. J Exp Med 2005
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15
Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.
Jason M Brenchley, Nitin J Karandikar, Michael R Betts, David R Ambrozak, Brenna J Hill, Laura E Crotty, Joseph P Casazza, Janaki Kuruppu, Stephen A Migueles, Mark Connors,[...]. Blood 2003
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CD28(-) T cells: their role in the age-associated decline of immune function.
Nan-Ping Weng, Arne N Akbar, Jorg Goronzy. Trends Immunol 2009
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Age-related changes in lymphocyte development and function.
Phyllis Jean Linton, Kenneth Dorshkind. Nat Immunol 2004
Phyllis Jean Linton, Kenneth Dorshkind. Nat Immunol 2004
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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.
F Sallusto, D Lenig, R Förster, M Lipp, A Lanzavecchia. Nature 1999
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Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections.
Victor Appay, P Rod Dunbar, Margaret Callan, Paul Klenerman, Geraldine M A Gillespie, Laura Papagno, Graham S Ogg, Abigail King, Franziska Lechner, Celsa A Spina,[...]. Nat Med 2002
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Phenotype and function of human T lymphocyte subsets: consensus and issues.
Victor Appay, Rene A W van Lier, Federica Sallusto, Mario Roederer. Cytometry A 2008
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Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals.
J J Goronzy, J W Fulbright, C S Crowson, G A Poland, W M O'Fallon, C M Weyand. J Virol 2001
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Aging of the innate immune system.
Albert C Shaw, Samit Joshi, Hannah Greenwood, Alexander Panda, Janet M Lord. Curr Opin Immunol 2010
Albert C Shaw, Samit Joshi, Hannah Greenwood, Alexander Panda, Janet M Lord. Curr Opin Immunol 2010
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The influence of age on T cell generation and TCR diversity.
Keith Naylor, Guangjin Li, Abbe N Vallejo, Won-Woo Lee, Kerstin Koetz, Ewa Bryl, Jacek Witkowski, James Fulbright, Cornelia M Weyand, Jörg J Goronzy. J Immunol 2005
Keith Naylor, Guangjin Li, Abbe N Vallejo, Won-Woo Lee, Kerstin Koetz, Ewa Bryl, Jacek Witkowski, James Fulbright, Cornelia M Weyand, Jörg J Goronzy. J Immunol 2005
11
Changes in thymic function with age and during the treatment of HIV infection.
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Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection.
Naeem Khan, Andrew Hislop, Nancy Gudgeon, Mark Cobbold, Rajiv Khanna, Laxman Nayak, Alan B Rickinson, Paul A H Moss. J Immunol 2004
Naeem Khan, Andrew Hislop, Nancy Gudgeon, Mark Cobbold, Rajiv Khanna, Laxman Nayak, Alan B Rickinson, Paul A H Moss. J Immunol 2004
11
Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion.
Jean M Fletcher, Milica Vukmanovic-Stejic, Padraic J Dunne, Katie E Birch, Joanne E Cook, Sarah E Jackson, Mike Salmon, Malcolm H Rustin, Arne N Akbar. J Immunol 2005
Jean M Fletcher, Milica Vukmanovic-Stejic, Padraic J Dunne, Katie E Birch, Joanne E Cook, Sarah E Jackson, Mike Salmon, Malcolm H Rustin, Arne N Akbar. J Immunol 2005
11
KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.
Sian M Henson, Ornella Franzese, Richard Macaulay, Valentina Libri, Rita I Azevedo, Sorena Kiani-Alikhan, Fiona J Plunkett, Joanne E Masters, Sarah Jackson, Stephen J Griffiths,[...]. Blood 2009
Sian M Henson, Ornella Franzese, Richard Macaulay, Valentina Libri, Rita I Azevedo, Sorena Kiani-Alikhan, Fiona J Plunkett, Joanne E Masters, Sarah Jackson, Stephen J Griffiths,[...]. Blood 2009
11
Is immunosenescence infectious?
Graham Pawelec, Arne Akbar, Calogero Caruso, Rita Effros, Beatrix Grubeck-Loebenstein, Anders Wikby. Trends Immunol 2004
Graham Pawelec, Arne Akbar, Calogero Caruso, Rita Effros, Beatrix Grubeck-Loebenstein, Anders Wikby. Trends Immunol 2004
10
Age-related CD8 T cell clonal expansions constrict CD8 T cell repertoire and have the potential to impair immune defense.
Ilhem Messaoudi, Joël Lemaoult, Jose A Guevara-Patino, Beatrix M Metzner, Janko Nikolich-Zugich. J Exp Med 2004
Ilhem Messaoudi, Joël Lemaoult, Jose A Guevara-Patino, Beatrix M Metzner, Janko Nikolich-Zugich. J Exp Med 2004
10
Age-related change in peripheral blood T-lymphocyte subpopulations and cytomegalovirus infection in the very old: the Swedish longitudinal OCTO immune study.
J Olsson, A Wikby, B Johansson, S Löfgren, B O Nilsson, F G Ferguson. Mech Ageing Dev 2000
J Olsson, A Wikby, B Johansson, S Löfgren, B O Nilsson, F G Ferguson. Mech Ageing Dev 2000
10
Phenotypic and functional separation of memory and effector human CD8+ T cells.
D Hamann, P A Baars, M H Rep, B Hooibrink, S R Kerkhof-Garde, M R Klein, R A van Lier. J Exp Med 1997
D Hamann, P A Baars, M H Rep, B Hooibrink, S R Kerkhof-Garde, M R Klein, R A van Lier. J Exp Med 1997
10
T cell development and receptor diversity during aging.
Jörg J Goronzy, Cornelia M Weyand. Curr Opin Immunol 2005
Jörg J Goronzy, Cornelia M Weyand. Curr Opin Immunol 2005
10
Human T cell aging and the impact of persistent viral infections.
T Fülöp, A Larbi, G Pawelec. Front Immunol 2013
T Fülöp, A Larbi, G Pawelec. Front Immunol 2013
10
Longitudinal studies of clonally expanded CD8 T cells reveal a repertoire shrinkage predicting mortality and an increased number of dysfunctional cytomegalovirus-specific T cells in the very elderly.
Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten, Anders Wikby. J Immunol 2006
Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten, Anders Wikby. J Immunol 2006
9
Will telomere erosion lead to a loss of T-cell memory?
Arne N Akbar, Peter C L Beverley, Mike Salmon. Nat Rev Immunol 2004
Arne N Akbar, Peter C L Beverley, Mike Salmon. Nat Rev Immunol 2004
10
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection.
Evelyna Derhovanessian, Anis Larbi, Graham Pawelec. Curr Opin Immunol 2009
Evelyna Derhovanessian, Anis Larbi, Graham Pawelec. Curr Opin Immunol 2009
9
Restoring function in exhausted CD8 T cells during chronic viral infection.
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
Daniel L Barber, E John Wherry, David Masopust, Baogong Zhu, James P Allison, Arlene H Sharpe, Gordon J Freeman, Rafi Ahmed. Nature 2006
9
Central memory and effector memory T cell subsets: function, generation, and maintenance.
Federica Sallusto, Jens Geginat, Antonio Lanzavecchia. Annu Rev Immunol 2004
Federica Sallusto, Jens Geginat, Antonio Lanzavecchia. Annu Rev Immunol 2004
9
Aging of the immune system: how much can the adaptive immune system adapt?
Nan-Ping Weng. Immunity 2006
Nan-Ping Weng. Immunity 2006
9
Reversible senescence in human CD4+CD45RA+CD27- memory T cells.
Diletta Di Mitri, Rita I Azevedo, Sian M Henson, Valentina Libri, Natalie E Riddell, Richard Macaulay, David Kipling, Maria V D Soares, Luca Battistini, Arne N Akbar. J Immunol 2011
Diletta Di Mitri, Rita I Azevedo, Sian M Henson, Valentina Libri, Natalie E Riddell, Richard Macaulay, David Kipling, Maria V D Soares, Luca Battistini, Arne N Akbar. J Immunol 2011
9
Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.
Giovanni Almanzar, Susanne Schwaiger, Brigitte Jenewein, Michael Keller, Dietmar Herndler-Brandstetter, Reinhard Würzner, Diether Schönitzer, Beatrix Grubeck-Loebenstein. J Virol 2005
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Human immunosenescence: is it infectious?
Graham Pawelec, Arne Akbar, Calogero Caruso, Rafael Solana, Beatrix Grubeck-Loebenstein, Anders Wikby. Immunol Rev 2005
Graham Pawelec, Arne Akbar, Calogero Caruso, Rafael Solana, Beatrix Grubeck-Loebenstein, Anders Wikby. Immunol Rev 2005
8
Changes in CD8 and CD4 lymphocyte subsets, T cell proliferation responses and non-survival in the very old: the Swedish longitudinal OCTO-immune study.
A Wikby, P Maxson, J Olsson, B Johansson, F G Ferguson. Mech Ageing Dev 1998
A Wikby, P Maxson, J Olsson, B Johansson, F G Ferguson. Mech Ageing Dev 1998
8
Age-associated accumulation of CMV-specific CD8+ T cells expressing the inhibitory killer cell lectin-like receptor G1 (KLRG1).
Qin Ouyang, Wolfgang M Wagner, David Voehringer, Anders Wikby, Tatjana Klatt, Steffen Walter, Claudia A Müller, Hanspeter Pircher, Graham Pawelec. Exp Gerontol 2003
Qin Ouyang, Wolfgang M Wagner, David Voehringer, Anders Wikby, Tatjana Klatt, Steffen Walter, Claudia A Müller, Hanspeter Pircher, Graham Pawelec. Exp Gerontol 2003
8
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans.
Claudio Franceschi, Miriam Capri, Daniela Monti, Sergio Giunta, Fabiola Olivieri, Federica Sevini, Maria Panagiota Panourgia, Laura Invidia, Laura Celani, Maria Scurti,[...]. Mech Ageing Dev 2007
Claudio Franceschi, Miriam Capri, Daniela Monti, Sergio Giunta, Fabiola Olivieri, Federica Sevini, Maria Panagiota Panourgia, Laura Invidia, Laura Celani, Maria Scurti,[...]. Mech Ageing Dev 2007
8
Cytomegalovirus-seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals.
S Chidrawar, N Khan, W Wei, A McLarnon, N Smith, L Nayak, P Moss. Clin Exp Immunol 2009
S Chidrawar, N Khan, W Wei, A McLarnon, N Smith, L Nayak, P Moss. Clin Exp Immunol 2009
8
The ageing immune system: is it ever too old to become young again?
Kenneth Dorshkind, Encarnacion Montecino-Rodriguez, Robert A J Signer. Nat Rev Immunol 2009
Kenneth Dorshkind, Encarnacion Montecino-Rodriguez, Robert A J Signer. Nat Rev Immunol 2009
8
Hallmarks of human "immunosenescence": adaptation or dysregulation?
Graham Pawelec. Immun Ageing 2012
Graham Pawelec. Immun Ageing 2012
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The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
8
Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study.
Anders Wikby, Boo Johansson, Jadwiga Olsson, Sture Löfgren, Bengt Olof Nilsson, Frederick Ferguson. Exp Gerontol 2002
Anders Wikby, Boo Johansson, Jadwiga Olsson, Sture Löfgren, Bengt Olof Nilsson, Frederick Ferguson. Exp Gerontol 2002
7
The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.
Fiona J Plunkett, Ornella Franzese, Helene M Finney, Jean M Fletcher, Lavina L Belaramani, Mike Salmon, Inderjeet Dokal, David Webster, Alastair D G Lawson, Arne N Akbar. J Immunol 2007
Fiona J Plunkett, Ornella Franzese, Helene M Finney, Jean M Fletcher, Lavina L Belaramani, Mike Salmon, Inderjeet Dokal, David Webster, Alastair D G Lawson, Arne N Akbar. J Immunol 2007
7
Hallmark features of immunosenescence are absent in familial longevity.
Evelyna Derhovanessian, Andrea B Maier, Robert Beck, Gerhard Jahn, Karin Hähnel, P Eline Slagboom, Anton J M de Craen, Rudi G J Westendorp, Graham Pawelec. J Immunol 2010
Evelyna Derhovanessian, Andrea B Maier, Robert Beck, Gerhard Jahn, Karin Hähnel, P Eline Slagboom, Anton J M de Craen, Rudi G J Westendorp, Graham Pawelec. J Immunol 2010
7
Immunosenescence: what does it mean to health outcomes in older adults?
Janet E McElhaney, Rita B Effros. Curr Opin Immunol 2009
Janet E McElhaney, Rita B Effros. Curr Opin Immunol 2009
7
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.
Susan M Kaech, Joyce T Tan, E John Wherry, Bogumila T Konieczny, Charles D Surh, Rafi Ahmed. Nat Immunol 2003
Susan M Kaech, Joyce T Tan, E John Wherry, Bogumila T Konieczny, Charles D Surh, Rafi Ahmed. Nat Immunol 2003
7
Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people.
Sven Koch, Anis Larbi, Evelyna Derhovanessian, Dennis Ozcelik, Elissaveta Naumova, Graham Pawelec. Immun Ageing 2008
Sven Koch, Anis Larbi, Evelyna Derhovanessian, Dennis Ozcelik, Elissaveta Naumova, Graham Pawelec. Immun Ageing 2008
7
7
7
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.
Pedro Romero, Alfred Zippelius, Isabel Kurth, Mikaël J Pittet, Cédric Touvrey, Emanuela M Iancu, Patricia Corthesy, Estelle Devevre, Daniel E Speiser, Nathalie Rufer. J Immunol 2007
Pedro Romero, Alfred Zippelius, Isabel Kurth, Mikaël J Pittet, Cédric Touvrey, Emanuela M Iancu, Patricia Corthesy, Estelle Devevre, Daniel E Speiser, Nathalie Rufer. J Immunol 2007
7
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.