Edward C Stack, James K Kubilus, Karen Smith, Kerry Cormier, Steven J Del Signore, Emmanuel Guelin, Hoon Ryu, Steven M Hersch, Robert J Ferrante. J Comp Neurol 2005
Times Cited: 185
Times Cited: 185
Times Cited
Times Co-cited
Similarity
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
L Mangiarini, K Sathasivam, M Seller, B Cozens, A Harper, C Hetherington, M Lawton, Y Trottier, H Lehrach, S W Davies,[...]. Cell 1996
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Neuropathological classification of Huntington's disease.
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
J P Vonsattel, R H Myers, T J Stevens, R J Ferrante, E D Bird, E P Richardson. J Neuropathol Exp Neurol 1985
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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain.
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
M DiFiglia, E Sapp, K O Chase, S W Davies, G P Bates, J P Vonsattel, N Aronin. Science 1997
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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
S W Davies, M Turmaine, B A Cozens, M DiFiglia, A H Sharp, C A Ross, E Scherzinger, E E Wanker, L Mangiarini, G P Bates. Cell 1997
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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
Elizabeth J Slow, Jeremy van Raamsdonk, Daniel Rogers, Sarah H Coleman, Rona K Graham, Yu Deng, Rosemary Oh, Nagat Bissada, Sazzad M Hossain, Yu-Zhou Yang,[...]. Hum Mol Genet 2003
31
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
Michelle Gray, Dyna I Shirasaki, Carlos Cepeda, Véronique M André, Brian Wilburn, Xiao-Hong Lu, Jifang Tao, Irene Yamazaki, Shi-Hua Li, Yi E Sun,[...]. J Neurosci 2008
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Neurological abnormalities in a knock-in mouse model of Huntington's disease.
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
C H Lin, S Tallaksen-Greene, W M Chien, J A Cearley, W S Jackson, A B Crouse, S Ren, X J Li, R L Albin, P J Detloff. Hum Mol Genet 2001
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Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.
R J Carter, L A Lione, T Humby, L Mangiarini, A Mahal, G P Bates, S B Dunnett, A J Morton. J Neurosci 1999
R J Carter, L A Lione, T Humby, L Mangiarini, A Mahal, G P Bates, S B Dunnett, A J Morton. J Neurosci 1999
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Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin.
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Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models.
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
Liliana Menalled, Bassem F El-Khodor, Monica Patry, Mayte Suárez-Fariñas, Samantha J Orenstein, Benjamin Zahasky, Christina Leahy, Vanessa Wheeler, X William Yang, Marcy MacDonald,[...]. Neurobiol Dis 2009
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Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
G J Klapstein, R S Fisher, H Zanjani, C Cepeda, E S Jokel, M F Chesselet, M S Levine. J Neurophysiol 2001
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Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
C Zuccato, A Ciammola, D Rigamonti, B R Leavitt, D Goffredo, L Conti, M E MacDonald, R M Friedlander, V Silani, M R Hayden,[...]. Science 2001
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Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
C A Gutekunst, S H Li, H Yi, J S Mulroy, S Kuemmerle, R Jones, D Rye, R J Ferrante, S M Hersch, X J Li. J Neurosci 1999
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Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
Liliana B Menalled, Jessica D Sison, Ioannis Dragatsis, Scott Zeitlin, Marie-Françoise Chesselet. J Comp Neurol 2003
16
Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
Liliana B Menalled, Andrea E Kudwa, Sam Miller, Jon Fitzpatrick, Judy Watson-Johnson, Nicole Keating, Melinda Ruiz, Richard Mushlin, William Alosio, Kristi McConnell,[...]. PLoS One 2012
16
Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice.
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
M A Hickey, A Kosmalska, J Enayati, R Cohen, S Zeitlin, M S Levine, M-F Chesselet. Neuroscience 2008
15
Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.
Jeremy M Van Raamsdonk, Jacqueline Pearson, Elizabeth J Slow, Sazzad M Hossain, Blair R Leavitt, Michael R Hayden. J Neurosci 2005
Jeremy M Van Raamsdonk, Jacqueline Pearson, Elizabeth J Slow, Sazzad M Hossain, Blair R Leavitt, Michael R Hayden. J Neurosci 2005
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Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease.
M Turmaine, A Raza, A Mahal, L Mangiarini, G P Bates, S W Davies. Proc Natl Acad Sci U S A 2000
M Turmaine, A Raza, A Mahal, L Mangiarini, G P Bates, S W Davies. Proc Natl Acad Sci U S A 2000
14
A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.
J G Hodgson, N Agopyan, C A Gutekunst, B R Leavitt, F LePiane, R Singaraja, D J Smith, N Bissada, K McCutcheon, J Nasir,[...]. Neuron 1999
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14
Evidence for more widespread cerebral pathology in early HD: an MRI-based morphometric analysis.
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
H D Rosas, W J Koroshetz, Y I Chen, C Skeuse, M Vangel, M E Cudkowicz, K Caplan, K Marek, L J Seidman, N Makris,[...]. Neurology 2003
14
Molecular mechanisms and potential therapeutical targets in Huntington's disease.
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
Chiara Zuccato, Marta Valenza, Elena Cattaneo. Physiol Rev 2010
14
Early behavioral deficits in R6/2 mice suitable for use in preclinical drug testing.
M A Hickey, K Gallant, G G Gross, M S Levine, Marie-Françoise Chesselet. Neurobiol Dis 2005
M A Hickey, K Gallant, G G Gross, M S Levine, Marie-Françoise Chesselet. Neurobiol Dis 2005
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Role of brain-derived neurotrophic factor in Huntington's disease.
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
Chiara Zuccato, Elena Cattaneo. Prog Neurobiol 2007
14
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
Laurent R Gauthier, Bénédicte C Charrin, Maria Borrell-Pagès, Jim P Dompierre, Hélène Rangone, Fabrice P Cordelières, Jan De Mey, Marcy E MacDonald, Volkmar Lessmann, Sandrine Humbert,[...]. Cell 2004
14
Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
Mahmoud A Pouladi, Lisa M Stanek, Yuanyun Xie, Sonia Franciosi, Amber L Southwell, Yu Deng, Stefanie Butland, Weining Zhang, Seng H Cheng, Lamya S Shihabuddin,[...]. Hum Mol Genet 2012
Mahmoud A Pouladi, Lisa M Stanek, Yuanyun Xie, Sonia Franciosi, Amber L Southwell, Yu Deng, Stefanie Butland, Weining Zhang, Seng H Cheng, Lamya S Shihabuddin,[...]. Hum Mol Genet 2012
14
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
Montserrat Arrasate, Siddhartha Mitra, Erik S Schweitzer, Mark R Segal, Steven Finkbeiner. Nature 2004
13
Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease.
Jeremy M Van Raamsdonk, Zoe Murphy, Elizabeth J Slow, Blair R Leavitt, Michael R Hayden. Hum Mol Genet 2005
Jeremy M Van Raamsdonk, Zoe Murphy, Elizabeth J Slow, Blair R Leavitt, Michael R Hayden. Hum Mol Genet 2005
13
Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
Taneli Heikkinen, Kimmo Lehtimäki, Nina Vartiainen, Jukka Puoliväli, Susan J Hendricks, Jack R Glaser, Amyaouch Bradaia, Kristian Wadel, Chrystelle Touller, Outi Kontkanen,[...]. PLoS One 2012
13
Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.
L A Lione, R J Carter, M J Hunt, G P Bates, A J Morton, S B Dunnett. J Neurosci 1999
L A Lione, R J Carter, M J Hunt, G P Bates, A J Morton, S B Dunnett. J Neurosci 1999
12
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice.
V C Wheeler, J K White, C A Gutekunst, V Vrbanac, M Weaver, X J Li, S H Li, H Yi, J P Vonsattel, J F Gusella,[...]. Hum Mol Genet 2000
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12
Standardization and statistical approaches to therapeutic trials in the R6/2 mouse.
Emma Hockly, Benjamin Woodman, Amarbirpal Mahal, Cathryn M Lewis, Gillian Bates. Brain Res Bull 2003
Emma Hockly, Benjamin Woodman, Amarbirpal Mahal, Cathryn M Lewis, Gillian Bates. Brain Res Bull 2003
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Differential loss of striatal projection neurons in Huntington disease.
A Reiner, R L Albin, K D Anderson, C J D'Amato, J B Penney, A B Young. Proc Natl Acad Sci U S A 1988
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Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.
Zhao-Xue Yu, Shi-Hua Li, Joy Evans, Ajay Pillarisetti, He Li, Xiao-Jiang Li. J Neurosci 2003
Zhao-Xue Yu, Shi-Hua Li, Joy Evans, Ajay Pillarisetti, He Li, Xiao-Jiang Li. J Neurosci 2003
11
Huntington's disease: can mice lead the way to treatment?
Zachary R Crook, David Housman. Neuron 2011
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Anterograde transport of brain-derived neurotrophic factor and its role in the brain.
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Brain-derived neurotrophic factor over-expression in the forebrain ameliorates Huntington's disease phenotypes in mice.
Kusumika Gharami, Yuxiang Xie, Juan Ji An, Susumu Tonegawa, Baoji Xu. J Neurochem 2008
Kusumika Gharami, Yuxiang Xie, Juan Ji An, Susumu Tonegawa, Baoji Xu. J Neurochem 2008
11
BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice.
Yuxiang Xie, Michael R Hayden, Baoji Xu. J Neurosci 2010
Yuxiang Xie, Michael R Hayden, Baoji Xu. J Neurosci 2010
11
In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.
Mathilde Faideau, Jinho Kim, Kerry Cormier, Richard Gilmore, Mackenzie Welch, Gwennaelle Auregan, Noelle Dufour, Martine Guillermier, Emmanuel Brouillet, Philippe Hantraye,[...]. Hum Mol Genet 2010
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11
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease.
Maria Björkqvist, Edward J Wild, Jenny Thiele, Aurelio Silvestroni, Ralph Andre, Nayana Lahiri, Elsa Raibon, Richard V Lee, Caroline L Benn, Denis Soulet,[...]. J Exp Med 2008
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11
Choosing an animal model for the study of Huntington's disease.
Mahmoud A Pouladi, A Jennifer Morton, Michael R Hayden. Nat Rev Neurosci 2013
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Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.
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10
Huntington's disease: from molecular pathogenesis to clinical treatment.
Christopher A Ross, Sarah J Tabrizi. Lancet Neurol 2011
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10
Animal models of Huntington's disease.
Shilpa Ramaswamy, Jodi L McBride, Jeffrey H Kordower. ILAR J 2007
Shilpa Ramaswamy, Jodi L McBride, Jeffrey H Kordower. ILAR J 2007
10
The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes.
Ben Woodman, Rachel Butler, Christian Landles, Michelle K Lupton, Jamie Tse, Emma Hockly, Hilary Moffitt, Kirupa Sathasivam, Gillian P Bates. Brain Res Bull 2007
Ben Woodman, Rachel Butler, Christian Landles, Michelle K Lupton, Jamie Tse, Emma Hockly, Hilary Moffitt, Kirupa Sathasivam, Gillian P Bates. Brain Res Bull 2007
10
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease.
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
R Luthi-Carter, A Strand, N L Peters, S M Solano, Z R Hollingsworth, A S Menon, A S Frey, B S Spektor, E B Penney, G Schilling,[...]. Hum Mol Genet 2000
10
The corticostriatal pathway in Huntington's disease.
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
Carlos Cepeda, Nanping Wu, Véronique M André, Damian M Cummings, Michael S Levine. Prog Neurobiol 2007
10
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
Josep M Canals, José R Pineda, Jesús F Torres-Peraza, Miquel Bosch, Raquel Martín-Ibañez, M Teresa Muñoz, Guadalupe Mengod, Patrik Ernfors, Jordi Alberch. J Neurosci 2004
Josep M Canals, José R Pineda, Jesús F Torres-Peraza, Miquel Bosch, Raquel Martín-Ibañez, M Teresa Muñoz, Guadalupe Mengod, Patrik Ernfors, Jordi Alberch. J Neurosci 2004
10
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.