Volodymyr I Dzhala, Delia M Talos, Dan A Sdrulla, Audrey C Brumback, Gregory C Mathews, Timothy A Benke, Eric Delpire, Frances E Jensen, Kevin J Staley. Nat Med 2005
Times Cited: 639
Times Cited: 639
Times Cited
Times Co-cited
Similarity
The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation.
C Rivera, J Voipio, J A Payne, E Ruusuvuori, H Lahtinen, K Lamsa, U Pirvola, M Saarma, K Kaila. Nature 1999
C Rivera, J Voipio, J A Payne, E Ruusuvuori, H Lahtinen, K Lamsa, U Pirvola, M Saarma, K Kaila. Nature 1999
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Excitatory actions of gaba during development: the nature of the nurture.
Yehezkel Ben-Ari. Nat Rev Neurosci 2002
Yehezkel Ben-Ari. Nat Rev Neurosci 2002
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Cation-chloride cotransporters and neuronal function.
Peter Blaesse, Matti S Airaksinen, Claudio Rivera, Kai Kaila. Neuron 2009
Peter Blaesse, Matti S Airaksinen, Claudio Rivera, Kai Kaila. Neuron 2009
21
Bumetanide for the treatment of seizures in newborn babies with hypoxic ischaemic encephalopathy (NEMO): an open-label, dose finding, and feasibility phase 1/2 trial.
Ronit M Pressler, Geraldine B Boylan, Neil Marlow, Mats Blennow, Catherine Chiron, J Helen Cross, Linda S de Vries, Boubou Hallberg, Lena Hellström-Westas, Vincent Jullien,[...]. Lancet Neurol 2015
Ronit M Pressler, Geraldine B Boylan, Neil Marlow, Mats Blennow, Catherine Chiron, J Helen Cross, Linda S de Vries, Boubou Hallberg, Lena Hellström-Westas, Vincent Jullien,[...]. Lancet Neurol 2015
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Cation-chloride cotransporters in neuronal development, plasticity and disease.
Kai Kaila, Theodore J Price, John A Payne, Martin Puskarjov, Juha Voipio. Nat Rev Neurosci 2014
Kai Kaila, Theodore J Price, John A Payne, Martin Puskarjov, Juha Voipio. Nat Rev Neurosci 2014
21
Cl- uptake promoting depolarizing GABA actions in immature rat neocortical neurones is mediated by NKCC1.
Junko Yamada, Akihito Okabe, Hiroki Toyoda, Werner Kilb, Heiko J Luhmann, Atsuo Fukuda. J Physiol 2004
Junko Yamada, Akihito Okabe, Hiroki Toyoda, Werner Kilb, Heiko J Luhmann, Atsuo Fukuda. J Physiol 2004
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GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations.
Yehezkel Ben-Ari, Jean-Luc Gaiarsa, Roman Tyzio, Rustem Khazipov. Physiol Rev 2007
Yehezkel Ben-Ari, Jean-Luc Gaiarsa, Roman Tyzio, Rustem Khazipov. Physiol Rev 2007
17
Giant synaptic potentials in immature rat CA3 hippocampal neurones.
Y Ben-Ari, E Cherubini, R Corradetti, J L Gaiarsa. J Physiol 1989
Y Ben-Ari, E Cherubini, R Corradetti, J L Gaiarsa. J Physiol 1989
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Phenobarbital compared with phenytoin for the treatment of neonatal seizures.
M J Painter, M S Scher, A D Stein, S Armatti, Z Wang, J C Gardiner, N Paneth, B Minnigh, J Alvin. N Engl J Med 1999
M J Painter, M S Scher, A D Stein, S Armatti, Z Wang, J C Gardiner, N Paneth, B Minnigh, J Alvin. N Engl J Med 1999
17
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model.
Volodymyr I Dzhala, Audrey C Brumback, Kevin J Staley. Ann Neurol 2008
Volodymyr I Dzhala, Audrey C Brumback, Kevin J Staley. Ann Neurol 2008
17
NKCC1 Chloride Importer Antagonists Attenuate Many Neurological and Psychiatric Disorders.
Yehezkel Ben-Ari. Trends Neurosci 2017
Yehezkel Ben-Ari. Trends Neurosci 2017
17
Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments.
Wolfgang Löscher, Martin Puskarjov, Kai Kaila. Neuropharmacology 2013
Wolfgang Löscher, Martin Puskarjov, Kai Kaila. Neuropharmacology 2013
16
Developmental Expression Patterns of KCC2 and Functionally Associated Molecules in the Human Brain.
Goran Sedmak, Nataša Jovanov-Milošević, Martin Puskarjov, Monika Ulamec, Božo Krušlin, Kai Kaila, Miloš Judaš. Cereb Cortex 2016
Goran Sedmak, Nataša Jovanov-Milošević, Martin Puskarjov, Monika Ulamec, Božo Krušlin, Kai Kaila, Miloš Judaš. Cereb Cortex 2016
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Neuronal chloride accumulation and excitatory GABA underlie aggravation of neonatal epileptiform activities by phenobarbital.
Romain Nardou, Sumii Yamamoto, Geneviève Chazal, Asma Bhar, Nadine Ferrand, Olivier Dulac, Yehezkel Ben-Ari, Ilgam Khalilov. Brain 2011
Romain Nardou, Sumii Yamamoto, Geneviève Chazal, Asma Bhar, Nadine Ferrand, Olivier Dulac, Yehezkel Ben-Ari, Ilgam Khalilov. Brain 2011
14
Perturbed chloride homeostasis and GABAergic signaling in human temporal lobe epilepsy.
Gilles Huberfeld, Lucia Wittner, Stéphane Clemenceau, Michel Baulac, Kai Kaila, Richard Miles, Claudio Rivera. J Neurosci 2007
Gilles Huberfeld, Lucia Wittner, Stéphane Clemenceau, Michel Baulac, Kai Kaila, Richard Miles, Claudio Rivera. J Neurosci 2007
14
Cation-chloride co-transporters in neuronal communication, development and trauma.
John A Payne, Claudio Rivera, Juha Voipio, Kai Kaila. Trends Neurosci 2003
John A Payne, Claudio Rivera, Juha Voipio, Kai Kaila. Trends Neurosci 2003
12
Development and regulation of chloride homeostasis in the central nervous system.
Miho Watanabe, Atsuo Fukuda. Front Cell Neurosci 2015
Miho Watanabe, Atsuo Fukuda. Front Cell Neurosci 2015
12
Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring.
Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal,[...]. Science 2014
Roman Tyzio, Romain Nardou, Diana C Ferrari, Timur Tsintsadze, Amene Shahrokhi, Sanaz Eftekhari, Ilgam Khalilov, Vera Tsintsadze, Corinne Brouchoud, Genevieve Chazal,[...]. Science 2014
12
Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures.
Martin Puskarjov, Kristopher T Kahle, Eva Ruusuvuori, Kai Kaila. Epilepsia 2014
Martin Puskarjov, Kristopher T Kahle, Eva Ruusuvuori, Kai Kaila. Epilepsia 2014
13
The GABA excitatory/inhibitory shift in brain maturation and neurological disorders.
Yehezkel Ben-Ari, Ilgam Khalilov, Kristopher T Kahle, Enrico Cherubini. Neuroscientist 2012
Yehezkel Ben-Ari, Ilgam Khalilov, Kristopher T Kahle, Enrico Cherubini. Neuroscientist 2012
12
Off-Label Use of Bumetanide for Brain Disorders: An Overview.
Shivani C Kharod, Seok Kyu Kang, Shilpa D Kadam. Front Neurosci 2019
Shivani C Kharod, Seok Kyu Kang, Shilpa D Kadam. Front Neurosci 2019
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Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride.
Valentin Stein, Irm Hermans-Borgmeyer, Thomas J Jentsch, Christian A Hübner. J Comp Neurol 2004
Valentin Stein, Irm Hermans-Borgmeyer, Thomas J Jentsch, Christian A Hübner. J Comp Neurol 2004
11
Slow endogenous activity transients and developmental expression of K+-Cl- cotransporter 2 in the immature human cortex.
Sampsa Vanhatalo, J Matias Palva, Sture Andersson, Claudio Rivera, Juha Voipio, Kai Kaila. Eur J Neurosci 2005
Sampsa Vanhatalo, J Matias Palva, Sture Andersson, Claudio Rivera, Juha Voipio, Kai Kaila. Eur J Neurosci 2005
11
Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition.
C A Hübner, V Stein, I Hermans-Borgmeyer, T Meyer, K Ballanyi, T J Jentsch. Neuron 2001
C A Hübner, V Stein, I Hermans-Borgmeyer, T Meyer, K Ballanyi, T J Jentsch. Neuron 2001
11
Cortical GABAergic excitation contributes to epileptic activities around human glioma.
Johan Pallud, Michel Le Van Quyen, Franck Bielle, Christophe Pellegrino, Pascale Varlet, Noemie Cresto, Michel Baulac, Charles Duyckaerts, Nazim Kourdougli, Geneviève Chazal,[...]. Sci Transl Med 2014
Johan Pallud, Michel Le Van Quyen, Franck Bielle, Christophe Pellegrino, Pascale Varlet, Noemie Cresto, Michel Baulac, Charles Duyckaerts, Nazim Kourdougli, Geneviève Chazal,[...]. Sci Transl Med 2014
11
On the origin of interictal activity in human temporal lobe epilepsy in vitro.
Ivan Cohen, Vincent Navarro, Stéphane Clemenceau, Michel Baulac, Richard Miles. Science 2002
Ivan Cohen, Vincent Navarro, Stéphane Clemenceau, Michel Baulac, Richard Miles. Science 2002
11
Roles of the cation-chloride cotransporters in neurological disease.
Kristopher T Kahle, Kevin J Staley, Brian V Nahed, Gerardo Gamba, Steven C Hebert, Richard P Lifton, David B Mount. Nat Clin Pract Neurol 2008
Kristopher T Kahle, Kevin J Staley, Brian V Nahed, Gerardo Gamba, Steven C Hebert, Richard P Lifton, David B Mount. Nat Clin Pract Neurol 2008
11
Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.
M Flagella, L L Clarke, M L Miller, L C Erway, R A Giannella, A Andringa, L R Gawenis, J Kramer, J J Duffy, T Doetschman,[...]. J Biol Chem 1999
M Flagella, L L Clarke, M L Miller, L C Erway, R A Giannella, A Andringa, L R Gawenis, J Kramer, J J Duffy, T Doetschman,[...]. J Biol Chem 1999
11
Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
E Delpire, J Lu, R England, C Dull, T Thorne. Nat Genet 1999
E Delpire, J Lu, R England, C Dull, T Thorne. Nat Genet 1999
11
Bumetanide enhances phenobarbital efficacy in a rat model of hypoxic neonatal seizures.
Ryan T Cleary, Hongyu Sun, Thanhthao Huynh, Simon M Manning, Yijun Li, Alexander Rotenberg, Delia M Talos, Kristopher T Kahle, Michele Jackson, Sanjay N Rakhade,[...]. PLoS One 2013
Ryan T Cleary, Hongyu Sun, Thanhthao Huynh, Simon M Manning, Yijun Li, Alexander Rotenberg, Delia M Talos, Kristopher T Kahle, Michele Jackson, Sanjay N Rakhade,[...]. PLoS One 2013
12
Age- and sex-dependent susceptibility to phenobarbital-resistant neonatal seizures: role of chloride co-transporters.
Seok Kyu Kang, Geoffrey J Markowitz, Shin Tae Kim, Michael V Johnston, Shilpa D Kadam. Front Cell Neurosci 2015
Seok Kyu Kang, Geoffrey J Markowitz, Shin Tae Kim, Michael V Johnston, Shilpa D Kadam. Front Cell Neurosci 2015
28
Local impermeant anions establish the neuronal chloride concentration.
J Glykys, V Dzhala, K Egawa, T Balena, Y Saponjian, K V Kuchibhotla, B J Bacskai, K T Kahle, T Zeuthen, K J Staley. Science 2014
J Glykys, V Dzhala, K Egawa, T Balena, Y Saponjian, K V Kuchibhotla, B J Bacskai, K T Kahle, T Zeuthen, K J Staley. Science 2014
10
Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus.
Sudhir Sivakumaran, Jamie Maguire. Epilepsia 2016
Sudhir Sivakumaran, Jamie Maguire. Epilepsia 2016
27
Chloride Regulation: A Dynamic Equilibrium Crucial for Synaptic Inhibition.
Nicolas Doyon, Laurent Vinay, Steven A Prescott, Yves De Koninck. Neuron 2016
Nicolas Doyon, Laurent Vinay, Steven A Prescott, Yves De Koninck. Neuron 2016
10
Direct protein kinase C-dependent phosphorylation regulates the cell surface stability and activity of the potassium chloride cotransporter KCC2.
Henry H C Lee, Joshua A Walker, Jeffery R Williams, Richard J Goodier, John A Payne, Stephen J Moss. J Biol Chem 2007
Henry H C Lee, Joshua A Walker, Jeffery R Williams, Richard J Goodier, John A Payne, Stephen J Moss. J Biol Chem 2007
10
NKCC1-dependent GABAergic excitation drives synaptic network maturation during early hippocampal development.
Carsten K Pfeffer, Valentin Stein, Damien J Keating, Hannes Maier, Ilka Rinke, York Rudhard, Moritz Hentschke, Gabriele M Rune, Thomas J Jentsch, Christian A Hübner. J Neurosci 2009
Carsten K Pfeffer, Valentin Stein, Damien J Keating, Hannes Maier, Ilka Rinke, York Rudhard, Moritz Hentschke, Gabriele M Rune, Thomas J Jentsch, Christian A Hübner. J Neurosci 2009
10
The cation-chloride cotransporter NKCC1 promotes sharp waves in the neonatal rat hippocampus.
Sampsa T Sipilä, Sebastian Schuchmann, Juha Voipio, Junko Yamada, Kai Kaila. J Physiol 2006
Sampsa T Sipilä, Sebastian Schuchmann, Juha Voipio, Junko Yamada, Kai Kaila. J Physiol 2006
10
Seizing Control of KCC2: A New Therapeutic Target for Epilepsy.
Yvonne E Moore, Matt R Kelley, Nicholas J Brandon, Tarek Z Deeb, Stephen J Moss. Trends Neurosci 2017
Yvonne E Moore, Matt R Kelley, Nicholas J Brandon, Tarek Z Deeb, Stephen J Moss. Trends Neurosci 2017
14
A novel prodrug-based strategy to increase effects of bumetanide in epilepsy.
Kathrin Töllner, Claudia Brandt, Manuel Töpfer, Gerda Brunhofer, Thomas Erker, Mario Gabriel, Peter W Feit, Jenna Lindfors, Kai Kaila, Wolfgang Löscher. Ann Neurol 2014
Kathrin Töllner, Claudia Brandt, Manuel Töpfer, Gerda Brunhofer, Thomas Erker, Mario Gabriel, Peter W Feit, Jenna Lindfors, Kai Kaila, Wolfgang Löscher. Ann Neurol 2014
12
A randomised controlled trial of bumetanide in the treatment of autism in children.
E Lemonnier, C Degrez, M Phelep, R Tyzio, F Josse, M Grandgeorge, N Hadjikhani, Y Ben-Ari. Transl Psychiatry 2012
E Lemonnier, C Degrez, M Phelep, R Tyzio, F Josse, M Grandgeorge, N Hadjikhani, Y Ben-Ari. Transl Psychiatry 2012
10
Expression of the Na-K-2Cl cotransporter is developmentally regulated in postnatal rat brains: a possible mechanism underlying GABA's excitatory role in immature brain.
M D Plotkin, E Y Snyder, S C Hebert, E Delpire. J Neurobiol 1997
M D Plotkin, E Y Snyder, S C Hebert, E Delpire. J Neurobiol 1997
10
Treatment during a vulnerable developmental period rescues a genetic epilepsy.
Stephan Lawrence Marguet, Vu Thao Quyen Le-Schulte, Andrea Merseburg, Axel Neu, Ronny Eichler, Igor Jakovcevski, Anton Ivanov, Ileana Livia Hanganu-Opatz, Christophe Bernard, Fabio Morellini,[...]. Nat Med 2015
Stephan Lawrence Marguet, Vu Thao Quyen Le-Schulte, Andrea Merseburg, Axel Neu, Ronny Eichler, Igor Jakovcevski, Anton Ivanov, Ileana Livia Hanganu-Opatz, Christophe Bernard, Fabio Morellini,[...]. Nat Med 2015
14
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.
Gerardo Gamba. Physiol Rev 2005
Gerardo Gamba. Physiol Rev 2005
9
Progressive NKCC1-dependent neuronal chloride accumulation during neonatal seizures.
Volodymyr I Dzhala, Kishore V Kuchibhotla, Joseph C Glykys, Kristopher T Kahle, Waldemar B Swiercz, Guoping Feng, Thomas Kuner, George J Augustine, Brian J Bacskai, Kevin J Staley. J Neurosci 2010
Volodymyr I Dzhala, Kishore V Kuchibhotla, Joseph C Glykys, Kristopher T Kahle, Waldemar B Swiercz, Guoping Feng, Thomas Kuner, George J Augustine, Brian J Bacskai, Kevin J Staley. J Neurosci 2010
9
Depolarizing GABA acts on intrinsically bursting pyramidal neurons to drive giant depolarizing potentials in the immature hippocampus.
Sampsa T Sipilä, Kristiina Huttu, Ivan Soltesz, Juha Voipio, Kai Kaila. J Neurosci 2005
Sampsa T Sipilä, Kristiina Huttu, Ivan Soltesz, Juha Voipio, Kai Kaila. J Neurosci 2005
9
GABA depolarizes immature neurons and inhibits network activity in the neonatal neocortex in vivo.
Knut Kirmse, Michael Kummer, Yury Kovalchuk, Otto W Witte, Olga Garaschuk, Knut Holthoff. Nat Commun 2015
Knut Kirmse, Michael Kummer, Yury Kovalchuk, Otto W Witte, Olga Garaschuk, Knut Holthoff. Nat Commun 2015
9
Simultaneous two-photon imaging of intracellular chloride concentration and pH in mouse pyramidal neurons in vivo.
Sebastian Sulis Sato, Pietro Artoni, Silvia Landi, Olga Cozzolino, Riccardo Parra, Enrico Pracucci, Francesco Trovato, Joanna Szczurkowska, Stefano Luin, Daniele Arosio,[...]. Proc Natl Acad Sci U S A 2017
Sebastian Sulis Sato, Pietro Artoni, Silvia Landi, Olga Cozzolino, Riccardo Parra, Enrico Pracucci, Francesco Trovato, Joanna Szczurkowska, Stefano Luin, Daniele Arosio,[...]. Proc Natl Acad Sci U S A 2017
15
BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion.
Claudio Rivera, Hong Li, Judith Thomas-Crusells, Hannele Lahtinen, Tero Viitanen, Avtandil Nanobashvili, Zaal Kokaia, Matti S Airaksinen, Juha Voipio, Kai Kaila,[...]. J Cell Biol 2002
Claudio Rivera, Hong Li, Judith Thomas-Crusells, Hannele Lahtinen, Tero Viitanen, Avtandil Nanobashvili, Zaal Kokaia, Matti S Airaksinen, Juha Voipio, Kai Kaila,[...]. J Cell Biol 2002
9
Reversing excitatory GABAAR signaling restores synaptic plasticity and memory in a mouse model of Down syndrome.
Gabriele Deidda, Martina Parrini, Shovan Naskar, Ignacio F Bozarth, Andrea Contestabile, Laura Cancedda. Nat Med 2015
Gabriele Deidda, Martina Parrini, Shovan Naskar, Ignacio F Bozarth, Andrea Contestabile, Laura Cancedda. Nat Med 2015
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.