Daekyu Sun, Kexiao Guo, Jadrian J Rusche, Laurence H Hurley. Nucleic Acids Res 2005
Times Cited: 296
Times Cited: 296
Times Cited
Times Co-cited
Similarity
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription.
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
Adam Siddiqui-Jain, Cory L Grand, David J Bearss, Laurence H Hurley. Proc Natl Acad Sci U S A 2002
69
G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcription.
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
Susanna Cogoi, Luigi E Xodo. Nucleic Acids Res 2006
48
Putative DNA quadruplex formation within the human c-kit oncogene.
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
Sarah Rankin, Anthony P Reszka, Julian Huppert, Mire Zloh, Gary N Parkinson, Alan K Todd, Sylvain Ladame, Shankar Balasubramanian, Stephen Neidle. J Am Chem Soc 2005
46
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
Shankar Balasubramanian, Laurence H Hurley, Stephen Neidle. Nat Rev Drug Discov 2011
41
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter.
Thomas S Dexheimer, Daekyu Sun, Laurence H Hurley. J Am Chem Soc 2006
Thomas S Dexheimer, Daekyu Sun, Laurence H Hurley. J Am Chem Soc 2006
39
Quadruplex DNA: sequence, topology and structure.
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
Sarah Burge, Gary N Parkinson, Pascale Hazel, Alan K Todd, Stephen Neidle. Nucleic Acids Res 2006
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Prevalence of quadruplexes in the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2005
36
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter.
Richard De Armond, Stacey Wood, Daekyu Sun, Laurence H Hurley, Scot W Ebbinghaus. Biochemistry 2005
Richard De Armond, Stacey Wood, Daekyu Sun, Laurence H Hurley, Scot W Ebbinghaus. Biochemistry 2005
33
Quantitative visualization of DNA G-quadruplex structures in human cells.
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
Giulia Biffi, David Tannahill, John McCafferty, Shankar Balasubramanian. Nat Chem 2013
30
A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene.
Himesh Fernando, Anthony P Reszka, Julian Huppert, Sylvain Ladame, Sarah Rankin, Ashok R Venkitaraman, Stephen Neidle, Shankar Balasubramanian. Biochemistry 2006
Himesh Fernando, Anthony P Reszka, Julian Huppert, Sylvain Ladame, Sarah Rankin, Ashok R Venkitaraman, Stephen Neidle, Shankar Balasubramanian. Biochemistry 2006
30
High-throughput sequencing of DNA G-quadruplex structures in the human genome.
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
Vicki S Chambers, Giovanni Marsico, Jonathan M Boutell, Marco Di Antonio, Geoffrey P Smith, Shankar Balasubramanian. Nat Biotechnol 2015
30
G-quadruplexes in promoters throughout the human genome.
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
Julian L Huppert, Shankar Balasubramanian. Nucleic Acids Res 2007
29
An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution.
Jixun Dai, Thomas S Dexheimer, Ding Chen, Megan Carver, Attila Ambrus, Roger A Jones, Danzhou Yang. J Am Chem Soc 2006
Jixun Dai, Thomas S Dexheimer, Ding Chen, Megan Carver, Attila Ambrus, Roger A Jones, Danzhou Yang. J Am Chem Soc 2006
26
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
Jixun Dai, Ding Chen, Roger A Jones, Laurence H Hurley, Danzhou Yang. Nucleic Acids Res 2006
26
Crystal structure of parallel quadruplexes from human telomeric DNA.
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
Gary N Parkinson, Michael P H Lee, Stephen Neidle. Nature 2002
24
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4.
Yong Qin, Evonne M Rezler, Vijay Gokhale, Daekyu Sun, Laurence H Hurley. Nucleic Acids Res 2007
Yong Qin, Evonne M Rezler, Vijay Gokhale, Daekyu Sun, Laurence H Hurley. Nucleic Acids Res 2007
23
Highly prevalent putative quadruplex sequence motifs in human DNA.
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
Alan K Todd, Matthew Johnston, Stephen Neidle. Nucleic Acids Res 2005
23
G-quadruplexes and their regulatory roles in biology.
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
Daniela Rhodes, Hans J Lipps. Nucleic Acids Res 2015
23
Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J Patel. J Am Chem Soc 2007
Anh Tuân Phan, Vitaly Kuryavyi, Sarah Burge, Stephen Neidle, Dinshaw J Patel. J Am Chem Soc 2007
21
Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis.
D Sen, W Gilbert. Nature 1988
D Sen, W Gilbert. Nature 1988
20
DNA tetraplex formation in the control region of c-myc.
T Simonsson, P Pecinka, M Kubista. Nucleic Acids Res 1998
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20
Human telomere, oncogenic promoter and 5'-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics.
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
Dinshaw J Patel, Anh Tuân Phan, Vitaly Kuryavyi. Nucleic Acids Res 2007
18
Solution structure of the human telomeric repeat d[AG3(T2AG3)3] G-tetraplex.
Y Wang, D J Patel. Structure 1993
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18
A hitchhiker's guide to G-quadruplex ligands.
David Monchaud, Marie-Paule Teulade-Fichou. Org Biomol Chem 2008
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18
DNA secondary structures: stability and function of G-quadruplex structures.
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
Matthew L Bochman, Katrin Paeschke, Virginia A Zakian. Nat Rev Genet 2012
18
Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization.
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
Attila Ambrus, Ding Chen, Jixun Dai, Roger A Jones, Danzhou Yang. Biochemistry 2005
17
17
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.
Kexiao Guo, Alan Pourpak, Kara Beetz-Rogers, Vijay Gokhale, Daekyu Sun, Laurence H Hurley. J Am Chem Soc 2007
Kexiao Guo, Alan Pourpak, Kara Beetz-Rogers, Vijay Gokhale, Daekyu Sun, Laurence H Hurley. J Am Chem Soc 2007
16
G-quadruplex structures mark human regulatory chromatin.
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
Robert Hänsel-Hertsch, Dario Beraldi, Stefanie V Lensing, Giovanni Marsico, Katherine Zyner, Aled Parry, Marco Di Antonio, Jeremy Pike, Hiroshi Kimura, Masashi Narita,[...]. Nat Genet 2016
16
Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands.
SunMi L Palumbo, Scot W Ebbinghaus, Laurence H Hurley. J Am Chem Soc 2009
SunMi L Palumbo, Scot W Ebbinghaus, Laurence H Hurley. J Am Chem Soc 2009
15
Stabilization of G-quadruplex DNA and down-regulation of oncogene c-myc by quindoline derivatives.
Tian-Miao Ou, Yu-Jing Lu, Chi Zhang, Zhi-Shu Huang, Xiao-Dong Wang, Jia-Heng Tan, Yuan Chen, Dik-Lung Ma, Kwok-Yin Wong, Johnny Cheuk-On Tang,[...]. J Med Chem 2007
Tian-Miao Ou, Yu-Jing Lu, Chi Zhang, Zhi-Shu Huang, Xiao-Dong Wang, Jia-Heng Tan, Yuan Chen, Dik-Lung Ma, Kwok-Yin Wong, Johnny Cheuk-On Tang,[...]. J Med Chem 2007
14
Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
Giulia Biffi, Marco Di Antonio, David Tannahill, Shankar Balasubramanian. Nat Chem 2014
14
DNA G-quadruplexes in the human genome: detection, functions and therapeutic potential.
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
Robert Hänsel-Hertsch, Marco Di Antonio, Shankar Balasubramanian. Nat Rev Mol Cell Biol 2017
14
Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene.
Kexiao Guo, Vijay Gokhale, Laurence H Hurley, Daekyu Sun. Nucleic Acids Res 2008
Kexiao Guo, Vijay Gokhale, Laurence H Hurley, Daekyu Sun. Nucleic Acids Res 2008
13
Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter.
Anh Tuân Phan, Yasha S Modi, Dinshaw J Patel. J Am Chem Soc 2004
Anh Tuân Phan, Yasha S Modi, Dinshaw J Patel. J Am Chem Soc 2004
13
Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb).
Yan Xu, Hiroshi Sugiyama. Nucleic Acids Res 2006
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13
Structural insights into G-quadruplexes: towards new anticancer drugs.
Danzhou Yang, Keika Okamoto. Future Med Chem 2010
Danzhou Yang, Keika Okamoto. Future Med Chem 2010
13
Inhibition of human telomerase by a G-quadruplex-interactive compound.
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
D Sun, B Thompson, B E Cathers, M Salazar, S M Kerwin, J O Trent, T C Jenkins, S Neidle, L H Hurley. J Med Chem 1997
13
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
Sunita Kumari, Anthony Bugaut, Julian L Huppert, Shankar Balasubramanian. Nat Chem Biol 2007
Sunita Kumari, Anthony Bugaut, Julian L Huppert, Shankar Balasubramanian. Nat Chem Biol 2007
13
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution.
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
Attila Ambrus, Ding Chen, Jixun Dai, Tiffanie Bialis, Roger A Jones, Danzhou Yang. Nucleic Acids Res 2006
12
The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4.
Jeyaprakashnarayanan Seenisamy, Evonne M Rezler, Tiffanie J Powell, Denise Tye, Vijay Gokhale, Chandana Sharma Joshi, Adam Siddiqui-Jain, Laurence H Hurley. J Am Chem Soc 2004
Jeyaprakashnarayanan Seenisamy, Evonne M Rezler, Tiffanie J Powell, Denise Tye, Vijay Gokhale, Chandana Sharma Joshi, Adam Siddiqui-Jain, Laurence H Hurley. J Am Chem Soc 2004
12
The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics.
Tracy A Brooks, Laurence H Hurley. Nat Rev Cancer 2009
Tracy A Brooks, Laurence H Hurley. Nat Rev Cancer 2009
12
G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells.
Keith I E McLuckie, Zoë A E Waller, Deborah A Sanders, David Alves, Raphaël Rodriguez, Jyotirmayee Dash, Grahame J McKenzie, Ashok R Venkitaraman, Shankar Balasubramanian. J Am Chem Soc 2011
Keith I E McLuckie, Zoë A E Waller, Deborah A Sanders, David Alves, Raphaël Rodriguez, Jyotirmayee Dash, Grahame J McKenzie, Ashok R Venkitaraman, Shankar Balasubramanian. J Am Chem Soc 2011
12
Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex.
Mu-Yong Kim, Hariprasad Vankayalapati, Kazuo Shin-Ya, Konstanty Wierzba, Laurence H Hurley. J Am Chem Soc 2002
Mu-Yong Kim, Hariprasad Vankayalapati, Kazuo Shin-Ya, Konstanty Wierzba, Laurence H Hurley. J Am Chem Soc 2002
12
A New G-Quadruplex with Hairpin Loop Immediately Upstream of the Human BCL2 P1 Promoter Modulates Transcription.
Buket Onel, Megan Carver, Guanhui Wu, Daria Timonina, Salil Kalarn, Marti Larriva, Danzhou Yang. J Am Chem Soc 2016
Buket Onel, Megan Carver, Guanhui Wu, Daria Timonina, Salil Kalarn, Marti Larriva, Danzhou Yang. J Am Chem Soc 2016
17
Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw, Dinshaw J Patel. Nat Chem Biol 2005
12
A novel G-quadruplex-forming GGA repeat region in the c-myb promoter is a critical regulator of promoter activity.
SunMi L Palumbo, Regan M Memmott, Diana J Uribe, Yulia Krotova-Khan, Laurence H Hurley, Scot W Ebbinghaus. Nucleic Acids Res 2008
SunMi L Palumbo, Regan M Memmott, Diana J Uribe, Yulia Krotova-Khan, Laurence H Hurley, Scot W Ebbinghaus. Nucleic Acids Res 2008
12
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function.
Angelika M Burger, Fangping Dai, Christoph M Schultes, Anthony P Reszka, Michael J Moore, John A Double, Stephen Neidle. Cancer Res 2005
Angelika M Burger, Fangping Dai, Christoph M Schultes, Anthony P Reszka, Michael J Moore, John A Double, Stephen Neidle. Cancer Res 2005
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Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
Raphaël Rodriguez, Kyle M Miller, Josep V Forment, Charles R Bradshaw, Mehran Nikan, Sébastien Britton, Tobias Oelschlaegel, Blerta Xhemalce, Shankar Balasubramanian, Stephen P Jackson. Nat Chem Biol 2012
11
G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry.
Jeffery T Davis. Angew Chem Int Ed Engl 2004
Jeffery T Davis. Angew Chem Int Ed Engl 2004
11
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