Peter Ahnesorg, Philippa Smith, Stephen P Jackson. Cell 2006
Times Cited: 556
Times Cited: 556
Times Cited
Times Co-cited
Similarity
Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.
Dietke Buck, Laurent Malivert, Régina de Chasseval, Anne Barraud, Marie-Claude Fondanèche, Ozden Sanal, Alessandro Plebani, Jean-Louis Stéphan, Markus Hufnagel, Françoise le Deist,[...]. Cell 2006
Dietke Buck, Laurent Malivert, Régina de Chasseval, Anne Barraud, Marie-Claude Fondanèche, Ozden Sanal, Alessandro Plebani, Jean-Louis Stéphan, Markus Hufnagel, Françoise le Deist,[...]. Cell 2006
45
DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair.
Takashi Ochi, Andrew N Blackford, Julia Coates, Satpal Jhujh, Shahid Mehmood, Naoka Tamura, Jon Travers, Qian Wu, Viji M Draviam, Carol V Robinson,[...]. Science 2015
Takashi Ochi, Andrew N Blackford, Julia Coates, Satpal Jhujh, Shahid Mehmood, Naoka Tamura, Jon Travers, Qian Wu, Viji M Draviam, Carol V Robinson,[...]. Science 2015
34
Non-homologous DNA end joining and alternative pathways to double-strand break repair.
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
Howard H Y Chang, Nicholas R Pannunzio, Noritaka Adachi, Michael R Lieber. Nat Rev Mol Cell Biol 2017
27
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination.
Yunmei Ma, Ulrich Pannicke, Klaus Schwarz, Michael R Lieber. Cell 2002
Yunmei Ma, Ulrich Pannicke, Klaus Schwarz, Michael R Lieber. Cell 2002
25
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway.
Michael R Lieber. Annu Rev Biochem 2010
Michael R Lieber. Annu Rev Biochem 2010
23
Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair.
J R Walker, R A Corpina, J Goldberg. Nature 2001
J R Walker, R A Corpina, J Goldberg. Nature 2001
23
Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells.
U Grawunder, M Wilm, X Wu, P Kulesza, T E Wilson, M Mann, M R Lieber. Nature 1997
U Grawunder, M Wilm, X Wu, P Kulesza, T E Wilson, M Mann, M R Lieber. Nature 1997
22
Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Mengtan Xing, Mingrui Yang, Wei Huo, Feng Feng, Leizhen Wei, Wenxia Jiang, Shaokai Ning, Zhenxin Yan, Wen Li, Qingsong Wang,[...]. Nat Commun 2015
Mengtan Xing, Mingrui Yang, Wei Huo, Feng Feng, Leizhen Wei, Wenxia Jiang, Shaokai Ning, Zhenxin Yan, Wen Li, Qingsong Wang,[...]. Nat Commun 2015
21
Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Virginie Ropars, Pascal Drevet, Pierre Legrand, Sonia Baconnais, Jeremy Amram, Guilhem Faure, José A Márquez, Olivier Piétrement, Raphaël Guerois, Isabelle Callebaut,[...]. Proc Natl Acad Sci U S A 2011
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21
The DNA-damage response in human biology and disease.
Stephen P Jackson, Jiri Bartek. Nature 2009
Stephen P Jackson, Jiri Bartek. Nature 2009
21
Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA.
Ineke Brouwer, Gerrit Sitters, Andrea Candelli, Stephanie J Heerema, Iddo Heller, Abinadabe J de Melo, Hongshan Zhang, Davide Normanno, Mauro Modesti, Erwin J G Peterman,[...]. Nature 2016
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20
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen.
T M Gottlieb, S P Jackson. Cell 1993
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19
Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair.
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DNA double-strand break repair-pathway choice in somatic mammalian cells.
Ralph Scully, Arvind Panday, Rajula Elango, Nicholas A Willis. Nat Rev Mol Cell Biol 2019
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A human XRCC4-XLF complex bridges DNA.
Sara N Andres, Alexandra Vergnes, Dejan Ristic, Claire Wyman, Mauro Modesti, Murray Junop. Nucleic Acids Res 2012
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Two-Stage Synapsis of DNA Ends during Non-homologous End Joining.
Thomas G W Graham, Johannes C Walter, Joseph J Loparo. Mol Cell 2016
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20
Double-strand break end resection and repair pathway choice.
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
Lorraine S Symington, Jean Gautier. Annu Rev Genet 2011
17
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair.
Michal Hammel, Martial Rey, Yaping Yu, Rajam S Mani, Scott Classen, Mona Liu, Michael E Pique, Shujuan Fang, Brandi L Mahaney, Michael Weinfeld,[...]. J Biol Chem 2011
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17
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.
Shan Zha, Chunguang Guo, Cristian Boboila, Valentyn Oksenych, Hwei-Ling Cheng, Yu Zhang, Duane R Wesemann, Grace Yuen, Harin Patel, Peter H Goff,[...]. Nature 2011
Shan Zha, Chunguang Guo, Cristian Boboila, Valentyn Oksenych, Hwei-Ling Cheng, Yu Zhang, Duane R Wesemann, Grace Yuen, Harin Patel, Peter H Goff,[...]. Nature 2011
17
PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF.
Satish K Tadi, Carine Tellier-Lebègue, Clément Nemoz, Pascal Drevet, Stéphane Audebert, Sunetra Roy, Katheryn Meek, Jean-Baptiste Charbonnier, Mauro Modesti. Cell Rep 2016
Satish K Tadi, Carine Tellier-Lebègue, Clément Nemoz, Pascal Drevet, Stéphane Audebert, Sunetra Roy, Katheryn Meek, Jean-Baptiste Charbonnier, Mauro Modesti. Cell Rep 2016
25
The DNA damage response: making it safe to play with knives.
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
Alberto Ciccia, Stephen J Elledge. Mol Cell 2010
16
Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.
Gang Li, Frederick W Alt, Hwei-Ling Cheng, James W Brush, Peter H Goff, Mike M Murphy, Sonia Franco, Yu Zhang, Shan Zha. Mol Cell 2008
Gang Li, Frederick W Alt, Hwei-Ling Cheng, James W Brush, Peter H Goff, Mike M Murphy, Sonia Franco, Yu Zhang, Shan Zha. Mol Cell 2008
15
PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.
Vipul Kumar, Frederick W Alt, Richard L Frock. Proc Natl Acad Sci U S A 2016
Vipul Kumar, Frederick W Alt, Richard L Frock. Proc Natl Acad Sci U S A 2016
21
Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining.
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Wenxia Jiang, Jennifer L Crowe, Xiangyu Liu, Satoshi Nakajima, Yunyue Wang, Chen Li, Brian J Lee, Richard L Dubois, Chao Liu, Xiaochun Yu,[...]. Mol Cell 2015
15
Dissection of DNA double-strand-break repair using novel single-molecule forceps.
Jing L Wang, Camille Duboc, Qian Wu, Takashi Ochi, Shikang Liang, Susan E Tsutakawa, Susan P Lees-Miller, Marc Nadal, John A Tainer, Tom L Blundell,[...]. Nat Struct Mol Biol 2018
Jing L Wang, Camille Duboc, Qian Wu, Takashi Ochi, Shikang Liang, Susan E Tsutakawa, Susan P Lees-Miller, Marc Nadal, John A Tainer, Tom L Blundell,[...]. Nat Struct Mol Biol 2018
29
Nonhomologous DNA end-joining for repair of DNA double-strand breaks.
Nicholas R Pannunzio, Go Watanabe, Michael R Lieber. J Biol Chem 2018
Nicholas R Pannunzio, Go Watanabe, Michael R Lieber. J Biol Chem 2018
14
Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ.
Yi Li, Dimitri Y Chirgadze, Victor M Bolanos-Garcia, Bancinyane L Sibanda, Owen R Davies, Peter Ahnesorg, Stephen P Jackson, Tom L Blundell. EMBO J 2008
Yi Li, Dimitri Y Chirgadze, Victor M Bolanos-Garcia, Bancinyane L Sibanda, Owen R Davies, Peter Ahnesorg, Stephen P Jackson, Tom L Blundell. EMBO J 2008
14
ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
Andrew N Blackford, Stephen P Jackson. Mol Cell 2017
14
Human CtIP promotes DNA end resection.
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
Alessandro A Sartori, Claudia Lukas, Julia Coates, Martin Mistrik, Shuang Fu, Jiri Bartek, Richard Baer, Jiri Lukas, Stephen P Jackson. Nature 2007
14
The essential elements for the noncovalent association of two DNA ends during NHEJ synapsis.
Bailin Zhao, Go Watanabe, Michael J Morten, Dylan A Reid, Eli Rothenberg, Michael R Lieber. Nat Commun 2019
Bailin Zhao, Go Watanabe, Michael J Morten, Dylan A Reid, Eli Rothenberg, Michael R Lieber. Nat Commun 2019
31
Ku recruits the XRCC4-ligase IV complex to DNA ends.
S A Nick McElhinny, C M Snowden, J McCarville, D A Ramsden. Mol Cell Biol 2000
S A Nick McElhinny, C M Snowden, J McCarville, D A Ramsden. Mol Cell Biol 2000
13
Crystal structure of human XLF: a twist in nonhomologous DNA end-joining.
Sara N Andres, Mauro Modesti, Chun J Tsai, Gilbert Chu, Murray S Junop. Mol Cell 2007
Sara N Andres, Mauro Modesti, Chun J Tsai, Gilbert Chu, Murray S Junop. Mol Cell 2007
13
MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Putzer J Hung, Britney Johnson, Bo-Ruei Chen, Andrea K Byrum, Andrea L Bredemeyer, William T Yewdell, Tanya E Johnson, Brian J Lee, Shruthi Deivasigamani, Issa Hindi,[...]. Mol Cell 2018
Putzer J Hung, Britney Johnson, Bo-Ruei Chen, Andrea K Byrum, Andrea L Bredemeyer, William T Yewdell, Tanya E Johnson, Brian J Lee, Shruthi Deivasigamani, Issa Hindi,[...]. Mol Cell 2018
22
XLF regulates filament architecture of the XRCC4·ligase IV complex.
Michal Hammel, Yaping Yu, Shujuan Fang, Susan P Lees-Miller, John A Tainer. Structure 2010
Michal Hammel, Yaping Yu, Shujuan Fang, Susan P Lees-Miller, John A Tainer. Structure 2010
14
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
Samuel F Bunting, Elsa Callén, Nancy Wong, Hua-Tang Chen, Federica Polato, Amanda Gunn, Anne Bothmer, Niklas Feldhahn, Oscar Fernandez-Capetillo, Liu Cao,[...]. Cell 2010
12
Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends.
Chun J Tsai, Sunny A Kim, Gilbert Chu. Proc Natl Acad Sci U S A 2007
Chun J Tsai, Sunny A Kim, Gilbert Chu. Proc Natl Acad Sci U S A 2007
12
DNA-PK autophosphorylation facilitates Artemis endonuclease activity.
Aaron A Goodarzi, Yaping Yu, Enriqueta Riballo, Pauline Douglas, Sarah A Walker, Ruiqiong Ye, Christine Härer, Caterina Marchetti, Nick Morrice, Penny A Jeggo,[...]. EMBO J 2006
Aaron A Goodarzi, Yaping Yu, Enriqueta Riballo, Pauline Douglas, Sarah A Walker, Ruiqiong Ye, Christine Härer, Caterina Marchetti, Nick Morrice, Penny A Jeggo,[...]. EMBO J 2006
12
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.
Jacob Falck, Julia Coates, Stephen P Jackson. Nature 2005
Jacob Falck, Julia Coates, Stephen P Jackson. Nature 2005
12
XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.
Brandi L Mahaney, Michal Hammel, Katheryn Meek, John A Tainer, Susan P Lees-Miller. Biochem Cell Biol 2013
Brandi L Mahaney, Michal Hammel, Katheryn Meek, John A Tainer, Susan P Lees-Miller. Biochem Cell Biol 2013
16
The molecular basis and disease relevance of non-homologous DNA end joining.
Bailin Zhao, Eli Rothenberg, Dale A Ramsden, Michael R Lieber. Nat Rev Mol Cell Biol 2020
Bailin Zhao, Eli Rothenberg, Dale A Ramsden, Michael R Lieber. Nat Rev Mol Cell Biol 2020
12
The shieldin complex mediates 53BP1-dependent DNA repair.
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
Sylvie M Noordermeer, Salomé Adam, Dheva Setiaputra, Marco Barazas, Stephen J Pettitt, Alexanda K Ling, Michele Olivieri, Alejandro Álvarez-Quilón, Nathalie Moatti, Michal Zimmermann,[...]. Nature 2018
11
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.
D Moshous, I Callebaut, R de Chasseval, B Corneo, M Cavazzana-Calvo, F Le Deist, I Tezcan, O Sanal, Y Bertrand, N Philippe,[...]. Cell 2001
D Moshous, I Callebaut, R de Chasseval, B Corneo, M Cavazzana-Calvo, F Le Deist, I Tezcan, O Sanal, Y Bertrand, N Philippe,[...]. Cell 2001
11
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
Lee Zou, Stephen J Elledge. Science 2003
Lee Zou, Stephen J Elledge. Science 2003
11
Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN.
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
Nausica Arnoult, Adriana Correia, Jiao Ma, Anna Merlo, Sara Garcia-Gomez, Marija Maric, Marco Tognetti, Christopher W Benner, Simon J Boulton, Alan Saghatelian,[...]. Nature 2017
11
DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.
Bancinyane L Sibanda, Dimitri Y Chirgadze, David B Ascher, Tom L Blundell. Science 2017
Bancinyane L Sibanda, Dimitri Y Chirgadze, David B Ascher, Tom L Blundell. Science 2017
11
Synthetic lethality between PAXX and XLF in mammalian development.
Gabriel Balmus, Ana C Barros, Paul W G Wijnhoven, Chloé Lescale, Hélène Lenden Hasse, Katharina Boroviak, Carlos le Sage, Brendan Doe, Anneliese O Speak, Antonella Galli,[...]. Genes Dev 2016
Gabriel Balmus, Ana C Barros, Paul W G Wijnhoven, Chloé Lescale, Hélène Lenden Hasse, Katharina Boroviak, Carlos le Sage, Brendan Doe, Anneliese O Speak, Antonella Galli,[...]. Genes Dev 2016
20
Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.
Chloé Lescale, Hélène Lenden Hasse, Andrew N Blackford, Gabriel Balmus, Joy J Bianchi, Wei Yu, Léa Bacoccina, Angélique Jarade, Christophe Clouin, Rohan Sivapalan,[...]. Cell Rep 2016
Chloé Lescale, Hélène Lenden Hasse, Andrew N Blackford, Gabriel Balmus, Joy J Bianchi, Wei Yu, Léa Bacoccina, Angélique Jarade, Christophe Clouin, Rohan Sivapalan,[...]. Cell Rep 2016
19
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guerois, Aurelien Pitois, Audrey Comte, Christine Delteil,[...]. Nat Struct Mol Biol 2018
Clement Nemoz, Virginie Ropars, Philippe Frit, Amandine Gontier, Pascal Drevet, Jinchao Yu, Raphaël Guerois, Aurelien Pitois, Audrey Comte, Christine Delteil,[...]. Nat Struct Mol Biol 2018
21
A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining.
Stephanie A Nick McElhinny, Jody M Havener, Miguel Garcia-Diaz, Raquel Juárez, Katarzyna Bebenek, Barbara L Kee, Luis Blanco, Thomas A Kunkel, Dale A Ramsden. Mol Cell 2005
Stephanie A Nick McElhinny, Jody M Havener, Miguel Garcia-Diaz, Raquel Juárez, Katarzyna Bebenek, Barbara L Kee, Luis Blanco, Thomas A Kunkel, Dale A Ramsden. Mol Cell 2005
11
Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination.
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
Pedro A Mateos-Gomez, Fade Gong, Nidhi Nair, Kyle M Miller, Eros Lazzerini-Denchi, Agnel Sfeir. Nature 2015
11
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.