A citation-based method for searching scientific literature

Jessica Svärd, Karin Heby-Henricson, Madelen Persson-Lek, Björn Rozell, Matthias Lauth, Asa Bergström, Johan Ericson, Rune Toftgård, Stephan Teglund. Dev Cell 2006
Times Cited: 348







List of co-cited articles
1431 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
303
39


Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
942
31

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
993
31

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.
Ayanna F Cooper, Kuan Ping Yu, Martina Brueckner, Lisa L Brailey, Linda Johnson, James M McGrath, Allen E Bale. Development 2005
141
31

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
945
30

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.
Miao-Hsueh Chen, Christopher W Wilson, Ya-Jun Li, Kelvin King Lo Law, Chi-Sheng Lu, Rhodora Gacayan, Xiaoyun Zhang, Chi-chung Hui, Pao-Tien Chuang. Genes Dev 2009
243
29

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
28

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
27


Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function.
Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder. PLoS Genet 2005
638
23


Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Danwei Huangfu, Aimin Liu, Andrew S Rakeman, Noel S Murcia, Lee Niswander, Kathryn V Anderson. Nature 2003
957
22

Gli proteins in development and disease.
Chi-Chung Hui, Stephane Angers. Annu Rev Cell Dev Biol 2011
430
22

Mutations in SUFU predispose to medulloblastoma.
Michael D Taylor, Ling Liu, Corey Raffel, Chi-chung Hui, Todd G Mainprize, Xiaoyun Zhang, Ron Agatep, Sharon Chiappa, Luzhang Gao, Anja Lowrance,[...]. Nat Genet 2002
560
20

Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1.
P Kogerman, T Grimm, L Kogerman, D Krause, A B Undén, B Sandstedt, R Toftgård, P G Zaphiropoulos. Nat Cell Biol 1999
363
20

Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
Yong Pan, Chunyang Brian Bai, Alexandra L Joyner, Baolin Wang. Mol Cell Biol 2006
378
19

The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling.
Saikat Mukhopadhyay, Xiaohui Wen, Navneet Ratti, Alexander Loktev, Linda Rangell, Suzie J Scales, Peter K Jackson. Cell 2013
263
18

Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia.
Jinping Jia, Asa Kolterud, Huiqing Zeng, Amber Hoover, Stephan Teglund, Rune Toftgård, Aimin Liu. Dev Biol 2009
101
18

Activating Smoothened mutations in sporadic basal-cell carcinoma.
J Xie, M Murone, S M Luoh, A Ryan, Q Gu, C Zhang, J M Bonifas, C W Lam, M Hynes, A Goddard,[...]. Nature 1998
982
18


Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing.
Baolin Wang, Yanyun Li. Proc Natl Acad Sci U S A 2006
203
17

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling.
Karel F Liem, Mu He, Polloneal Jymmiel R Ocbina, Kathryn V Anderson. Proc Natl Acad Sci U S A 2009
189
17

Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.
Xiaohui Wen, Cary K Lai, Marie Evangelista, Jo-Anne Hongo, Frederic J de Sauvage, Suzie J Scales. Mol Cell Biol 2010
169
17

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.
R L Johnson, A L Rothman, J Xie, L V Goodrich, J W Bare, J M Bonifas, A G Quinn, R M Myers, D R Cox, E H Epstein,[...]. Science 1996
17


Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
Yongbin Chen, Noriaki Sasai, Guoqiang Ma, Tao Yue, Jianhang Jia, James Briscoe, Jin Jiang. PLoS Biol 2011
136
15

Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
15

Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli.
D M Stone, M Murone, S Luoh, W Ye, M P Armanini, A Gurney, H Phillips, J Brush, A Goddard, F J de Sauvage,[...]. J Cell Sci 1999
123
15

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.
J Taipale, J K Chen, M K Cooper, B Wang, R K Mann, L Milenkovic, M P Scott, P A Beachy. Nature 2000
15


Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.
Pawel Niewiadomski, Jennifer H Kong, Robert Ahrends, Yan Ma, Eric W Humke, Sohini Khan, Mary N Teruel, Bennett G Novitch, Rajat Rohatgi. Cell Rep 2014
133
15

Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.
Denis Tempé, Mariana Casas, Sonia Karaz, Marie-Françoise Blanchet-Tournier, Jean-Paul Concordet. Mol Cell Biol 2006
180
15


Patched acts catalytically to suppress the activity of Smoothened.
J Taipale, M K Cooper, T Maiti, P A Beachy. Nature 2002
571
14

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment.
Mu He, Radhika Subramanian, Fiona Bangs, Tatiana Omelchenko, Karel F Liem, Tarun M Kapoor, Kathryn V Anderson. Nat Cell Biol 2014
168
14

Primary Cilia and Mammalian Hedgehog Signaling.
Fiona Bangs, Kathryn V Anderson. Cold Spring Harb Perspect Biol 2017
225
14

Suppressor of fused regulates Gli activity through a dual binding mechanism.
Mark Merchant, Felix F Vajdos, Mark Ultsch, Henry R Maun, Ulrich Wendt, Jennifer Cannon, William Desmarais, Robert A Lazarus, Abraham M de Vos, Frederic J de Sauvage. Mol Cell Biol 2004
84
15


The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
D M Stone, M Hynes, M Armanini, T A Swanson, Q Gu, R L Johnson, M P Scott, D Pennica, A Goddard, H Phillips,[...]. Nature 1996
892
13

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.
Robert L Yauch, Gerrit J P Dijkgraaf, Bruno Alicke, Thomas Januario, Christina P Ahn, Thomas Holcomb, Kanan Pujara, Jeremy Stinson, Christopher A Callahan, Tracy Tang,[...]. Science 2009
617
13

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
13


A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.
Qing Zhang, Lei Zhang, Bing Wang, Chan-Yen Ou, Cheng-Ting Chien, Jin Jiang. Dev Cell 2006
182
12

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.
Marcel Kool, David T W Jones, Natalie Jäger, Paul A Northcott, Trevor J Pugh, Volker Hovestadt, Rosario M Piro, L Adriana Esparza, Shirley L Markant, Marc Remke,[...]. Cancer Cell 2014
422
12

Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma.
Hayley J Sharpe, Gregoire Pau, Gerrit J Dijkgraaf, Nicole Basset-Seguin, Zora Modrusan, Thomas Januario, Vickie Tsui, Alison B Durham, Andrzej A Dlugosz, Peter M Haverty,[...]. Cancer Cell 2015
221
12

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome.
H Hahn, C Wicking, P G Zaphiropoulous, M R Gailani, S Shanley, A Chidambaram, I Vorechovsky, E Holmberg, A B Unden, S Gillies,[...]. Cell 1996
12

The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.
Setsu Endoh-Yamagami, Marie Evangelista, Deanna Wilson, Xiaohui Wen, Jan-Willem Theunissen, Khanhky Phamluong, Matti Davis, Suzie J Scales, Mark J Solloway, Frederic J de Sauvage,[...]. Curr Biol 2009
153
12

Cilia and Hedgehog responsiveness in the mouse.
Danwei Huangfu, Kathryn V Anderson. Proc Natl Acad Sci U S A 2005
591
12

Smoothened variants explain the majority of drug resistance in basal cell carcinoma.
Scott X Atwood, Kavita Y Sarin, Ramon J Whitson, Jiang R Li, Geurim Kim, Melika Rezaee, Mina S Ally, Jinah Kim, Catherine Yao, Anne Lynn S Chang,[...]. Cancer Cell 2015
238
12


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.