Alessandra Vacca, Maria Pia Felli, Rocco Palermo, Giuseppina Di Mario, Angelica Calce, Monica Di Giovine, Luigi Frati, Alberto Gulino, Isabella Screpanti. EMBO J 2006
Times Cited: 113
Times Cited: 113
Times Cited
Times Co-cited
Similarity
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice.
D Bellavia, A F Campese, E Alesse, A Vacca, M P Felli, A Balestri, A Stoppacciaro, C Tiveron, L Tatangelo, M Giovarelli,[...]. EMBO J 2000
D Bellavia, A F Campese, E Alesse, A Vacca, M P Felli, A Balestri, A Stoppacciaro, C Tiveron, L Tatangelo, M Giovarelli,[...]. EMBO J 2000
32
Notch signaling: cell fate control and signal integration in development.
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
S Artavanis-Tsakonas, M D Rand, R J Lake. Science 1999
31
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
Tomas Vilimas, Joaquina Mascarenhas, Teresa Palomero, Malay Mandal, Silvia Buonamici, Fanyong Meng, Benjamín Thompson, Christina Spaulding, Sami Macaroun, Maria-Luisa Alegre,[...]. Nat Med 2007
30
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
27
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
Diana Bellavia, Antonio F Campese, Saula Checquolo, Anna Balestri, Andrea Biondi, Giovanni Cazzaniga, Urban Lendahl, Hans J Fehling, Adrian C Hayday, Luigi Frati,[...]. Proc Natl Acad Sci U S A 2002
Diana Bellavia, Antonio F Campese, Saula Checquolo, Anna Balestri, Andrea Biondi, Giovanni Cazzaniga, Urban Lendahl, Hans J Fehling, Adrian C Hayday, Luigi Frati,[...]. Proc Natl Acad Sci U S A 2002
25
Notch1 augments NF-kappaB activity by facilitating its nuclear retention.
Hyun Mu Shin, Lisa M Minter, Ok Hyun Cho, Sridevi Gottipati, Abdul H Fauq, Todd E Golde, Gail E Sonenshein, Barbara A Osborne. EMBO J 2006
Hyun Mu Shin, Lisa M Minter, Ok Hyun Cho, Sridevi Gottipati, Abdul H Fauq, Todd E Golde, Gail E Sonenshein, Barbara A Osborne. EMBO J 2006
24
The canonical Notch signaling pathway: unfolding the activation mechanism.
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
Raphael Kopan, Maria Xenia G Ilagan. Cell 2009
21
Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes.
Emanuela Anastasi, Antonio F Campese, Diana Bellavia, Angela Bulotta, Anna Balestri, Monica Pascucci, Saula Checquolo, Roberto Gradini, Urban Lendahl, Luigi Frati,[...]. J Immunol 2003
Emanuela Anastasi, Antonio F Campese, Diana Bellavia, Angela Bulotta, Anna Balestri, Monica Pascucci, Saula Checquolo, Roberto Gradini, Urban Lendahl, Luigi Frati,[...]. J Immunol 2003
15
14
PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia.
Maria Pia Felli, Alessandra Vacca, Angelica Calce, Diana Bellavia, Antonio F Campese, Rita Grillo, Monica Di Giovine, Saula Checquolo, Claudio Talora, Rocco Palermo,[...]. Oncogene 2005
Maria Pia Felli, Alessandra Vacca, Angelica Calce, Diana Bellavia, Antonio F Campese, Rita Grillo, Monica Di Giovine, Saula Checquolo, Claudio Talora, Rocco Palermo,[...]. Oncogene 2005
23
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma.
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
Andrew P Weng, John M Millholland, Yumi Yashiro-Ohtani, Marie Laure Arcangeli, Arthur Lau, Carol Wai, Cristina Del Bianco, Carlos G Rodriguez, Hong Sai, John Tobias,[...]. Genes Dev 2006
14
TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
L W Ellisen, J Bird, D C West, A L Soreng, T C Reynolds, S D Smith, J Sklar. Cell 1991
14
Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.
L L Song, Y Peng, J Yun, P Rizzo, V Chaturvedi, S Weijzen, W M Kast, P J B Stone, L Santos, A Loredo,[...]. Oncogene 2008
L L Song, Y Peng, J Yun, P Rizzo, V Chaturvedi, S Weijzen, W M Kast, P J B Stone, L Santos, A Loredo,[...]. Oncogene 2008
14
Notch-1 regulates NF-kappaB activity in hemopoietic progenitor cells.
P Cheng, A Zlobin, V Volgina, S Gottipati, B Osborne, E J Simel, L Miele, D I Gabrilovich. J Immunol 2001
P Cheng, A Zlobin, V Volgina, S Gottipati, B Osborne, E J Simel, L Miele, D I Gabrilovich. J Immunol 2001
13
The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.
Lluis Espinosa, Severine Cathelin, Teresa D'Altri, Thomas Trimarchi, Alexander Statnikov, Jordi Guiu, Veronica Rodilla, Julia Inglés-Esteve, Josep Nomdedeu, Beatriz Bellosillo,[...]. Cancer Cell 2010
Lluis Espinosa, Severine Cathelin, Teresa D'Altri, Thomas Trimarchi, Alexander Statnikov, Jordi Guiu, Veronica Rodilla, Julia Inglés-Esteve, Josep Nomdedeu, Beatriz Bellosillo,[...]. Cancer Cell 2010
13
Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.
Derk Amsen, J Magarian Blander, Gap Ryol Lee, Kenji Tanigaki, Tasuku Honjo, Richard A Flavell. Cell 2004
Derk Amsen, J Magarian Blander, Gap Ryol Lee, Kenji Tanigaki, Tasuku Honjo, Richard A Flavell. Cell 2004
12
Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.
Clemens Grabher, Harald von Boehmer, A Thomas Look. Nat Rev Cancer 2006
Clemens Grabher, Harald von Boehmer, A Thomas Look. Nat Rev Cancer 2006
12
Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.
Alessandro Barbarulo, Paola Grazioli, Antonio F Campese, Diana Bellavia, Giuseppina Di Mario, Maria Pelullo, Ambra Ciuffetta, Sara Colantoni, Alessandra Vacca, Luigi Frati,[...]. J Immunol 2011
Alessandro Barbarulo, Paola Grazioli, Antonio F Campese, Diana Bellavia, Giuseppina Di Mario, Maria Pelullo, Ambra Ciuffetta, Sara Colantoni, Alessandra Vacca, Luigi Frati,[...]. J Immunol 2011
21
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies.
P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, P Capodieci, J Deplazes-Lauber, K Petropoulos, P Thiel,[...]. Oncogene 2016
P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, P Capodieci, J Deplazes-Lauber, K Petropoulos, P Thiel,[...]. Oncogene 2016
22
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors.
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
Jennifer O'Neil, Jonathan Grim, Peter Strack, Sudhir Rao, Deanne Tibbitts, Christopher Winter, James Hardwick, Markus Welcker, Jules P Meijerink, Rob Pieters,[...]. J Exp Med 2007
11
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability.
Chin-Tong Ong, Hui-Teng Cheng, Li-Wei Chang, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Gary D Stormo, Raphael Kopan. J Biol Chem 2006
Chin-Tong Ong, Hui-Teng Cheng, Li-Wei Chang, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Gary D Stormo, Raphael Kopan. J Biol Chem 2006
11
Non-canonical notch signaling in cancer and immunity.
Furkan Ayaz, Barbara A Osborne. Front Oncol 2014
Furkan Ayaz, Barbara A Osborne. Front Oncol 2014
11
Notch3 is required for arterial identity and maturation of vascular smooth muscle cells.
Valérie Domenga, Peggy Fardoux, Pierre Lacombe, Marie Monet, Jacqueline Maciazek, Luke T Krebs, Bernard Klonjkowski, Eliane Berrou, Matthias Mericskay, Zhen Li,[...]. Genes Dev 2004
Valérie Domenga, Peggy Fardoux, Pierre Lacombe, Marie Monet, Jacqueline Maciazek, Luke T Krebs, Bernard Klonjkowski, Eliane Berrou, Matthias Mericskay, Zhen Li,[...]. Genes Dev 2004
10
Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.
W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
W S Pear, J C Aster, M L Scott, R P Hasserjian, B Soffer, J Sklar, D Baltimore. J Exp Med 1996
10
Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma.
Claudio Talora, Antonio F Campese, Diana Bellavia, Monica Pascucci, Saula Checquolo, Manuela Groppioni, Luigi Frati, Harald von Boehmer, Alberto Gulino, Isabella Screpanti. EMBO Rep 2003
Claudio Talora, Antonio F Campese, Diana Bellavia, Monica Pascucci, Saula Checquolo, Manuela Groppioni, Luigi Frati, Harald von Boehmer, Alberto Gulino, Isabella Screpanti. EMBO Rep 2003
15
Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing.
Diana Bellavia, Marco Mecarozzi, Antonio F Campese, Paola Grazioli, Claudio Talora, Luigi Frati, Alberto Gulino, Isabella Screpanti. EMBO J 2007
Diana Bellavia, Marco Mecarozzi, Antonio F Campese, Paola Grazioli, Claudio Talora, Luigi Frati, Alberto Gulino, Isabella Screpanti. EMBO J 2007
14
Direct inhibition of the NOTCH transcription factor complex.
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
Raymond E Moellering, Melanie Cornejo, Tina N Davis, Cristina Del Bianco, Jon C Aster, Stephen C Blacklow, Andrew L Kung, D Gary Gilliland, Gregory L Verdine, James E Bradner. Nature 2009
10
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
10
Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.
V Kumar, R Palermo, C Talora, A F Campese, S Checquolo, D Bellavia, L Tottone, G Testa, E Miele, S Indraccolo,[...]. Leukemia 2014
V Kumar, R Palermo, C Talora, A F Campese, S Checquolo, D Bellavia, L Tottone, G Testa, E Miele, S Indraccolo,[...]. Leukemia 2014
10
Human Notch-1 inhibits NF-kappa B activity in the nucleus through a direct interaction involving a novel domain.
J Wang, L Shelly, L Miele, R Boykins, M A Norcross, E Guan. J Immunol 2001
J Wang, L Shelly, L Miele, R Boykins, M A Norcross, E Guan. J Immunol 2001
9
NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa.
F Oswald, S Liptay, G Adler, R M Schmid. Mol Cell Biol 1998
F Oswald, S Liptay, G Adler, R M Schmid. Mol Cell Biol 1998
9
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth.
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
Teresa Palomero, Wei Keat Lim, Duncan T Odom, Maria Luisa Sulis, Pedro J Real, Adam Margolin, Kelly C Barnes, Jennifer O'Neil, Donna Neuberg, Andrew P Weng,[...]. Proc Natl Acad Sci U S A 2006
9
Off the beaten pathway: the complex cross talk between Notch and NF-kappaB.
Clodia Osipo, Todd E Golde, Barbara A Osborne, Lucio A Miele. Lab Invest 2008
Clodia Osipo, Todd E Golde, Barbara A Osborne, Lucio A Miele. Lab Invest 2008
9
Non-canonical Notch signaling activates IL-6/JAK/STAT signaling in breast tumor cells and is controlled by p53 and IKKα/IKKβ.
S Jin, A P Mutvei, I V Chivukula, E R Andersson, D Ramsköld, R Sandberg, K L Lee, P Kronqvist, V Mamaeva, P Ostling,[...]. Oncogene 2013
S Jin, A P Mutvei, I V Chivukula, E R Andersson, D Ramsköld, R Sandberg, K L Lee, P Kronqvist, V Mamaeva, P Ostling,[...]. Oncogene 2013
9
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation.
A Rangarajan, C Talora, R Okuyama, M Nicolas, C Mammucari, H Oh, J C Aster, S Krishna, D Metzger, P Chambon,[...]. EMBO J 2001
A Rangarajan, C Talora, R Okuyama, M Nicolas, C Mammucari, H Oh, J C Aster, S Krishna, D Metzger, P Chambon,[...]. EMBO J 2001
8
TCR-mediated Notch signaling regulates proliferation and IFN-gamma production in peripheral T cells.
Tanapat Palaga, Lucio Miele, Todd E Golde, Barbara A Osborne. J Immunol 2003
Tanapat Palaga, Lucio Miele, Todd E Golde, Barbara A Osborne. J Immunol 2003
8
Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.
Lisa M Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer,[...]. Nat Immunol 2005
Lisa M Minter, Danielle M Turley, Pritam Das, Hyun Mu Shin, Ila Joshi, Rebecca G Lawlor, Ok Hyun Cho, Tanapat Palaga, Sridevi Gottipati, Janice C Telfer,[...]. Nat Immunol 2005
8
Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision.
Hua Han, Kenji Tanigaki, Norio Yamamoto, Kazuki Kuroda, Momoko Yoshimoto, Tatsutoshi Nakahata, Koichi Ikuta, Tasuku Honjo. Int Immunol 2002
Hua Han, Kenji Tanigaki, Norio Yamamoto, Kazuki Kuroda, Momoko Yoshimoto, Tatsutoshi Nakahata, Koichi Ikuta, Tasuku Honjo. Int Immunol 2002
8
Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes.
Stéphane Vigouroux, Eric Yvon, Hans-Joachim Wagner, Ettore Biagi, Gianpietro Dotti, Uluhan Sili, Cecilia Lira, Cliona M Rooney, Malcolm K Brenner. J Virol 2003
Stéphane Vigouroux, Eric Yvon, Hans-Joachim Wagner, Ettore Biagi, Gianpietro Dotti, Uluhan Sili, Cecilia Lira, Cliona M Rooney, Malcolm K Brenner. J Virol 2003
8
NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development.
R E Voll, E Jimi, R J Phillips, D F Barber, M Rincon, A C Hayday, R A Flavell, S Ghosh. Immunity 2000
R E Voll, E Jimi, R J Phillips, D F Barber, M Rincon, A C Hayday, R A Flavell, S Ghosh. Immunity 2000
8
IkappaBalpha and p65 regulate the cytoplasmic shuttling of nuclear corepressors: cross-talk between Notch and NFkappaB pathways.
Lluís Espinosa, Julia Inglés-Esteve, Alex Robert-Moreno, Anna Bigas. Mol Biol Cell 2003
Lluís Espinosa, Julia Inglés-Esteve, Alex Robert-Moreno, Anna Bigas. Mol Biol Cell 2003
9
Notch1-dependent lymphomagenesis is assisted by but does not essentially require pre-TCR signaling.
Antonio F Campese, Annette I Garbe, Fangrong Zhang, Fabio Grassi, Isabella Screpanti, Harald von Boehmer. Blood 2006
Antonio F Campese, Annette I Garbe, Fangrong Zhang, Fabio Grassi, Isabella Screpanti, Harald von Boehmer. Blood 2006
14
Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis.
Claudio Talora, Samantha Cialfi, Christian Oliviero, Rocco Palermo, Monica Pascucci, Luigi Frati, Alessandra Vacca, Alberto Gulino, Isabella Screpanti. Blood 2006
Claudio Talora, Samantha Cialfi, Christian Oliviero, Rocco Palermo, Monica Pascucci, Luigi Frati, Alessandra Vacca, Alberto Gulino, Isabella Screpanti. Blood 2006
24
Notch3 gene amplification in ovarian cancer.
Joon T Park, Mei Li, Kentaro Nakayama, Tsui-Lien Mao, Ben Davidson, Zhen Zhang, Robert J Kurman, Charles G Eberhart, Ie-Ming Shih, Tian-Li Wang. Cancer Res 2006
Joon T Park, Mei Li, Kentaro Nakayama, Tsui-Lien Mao, Ben Davidson, Zhen Zhang, Robert J Kurman, Charles G Eberhart, Ie-Ming Shih, Tian-Li Wang. Cancer Res 2006
8
Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.
M P Felli, M Maroder, T A Mitsiadis, A F Campese, D Bellavia, A Vacca, R S Mann, L Frati, U Lendahl, A Gulino,[...]. Int Immunol 1999
M P Felli, M Maroder, T A Mitsiadis, A F Campese, D Bellavia, A Vacca, R S Mann, L Frati, U Lendahl, A Gulino,[...]. Int Immunol 1999
8
Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells.
Jeremy B Samon, Ameya Champhekar, Lisa M Minter, Janice C Telfer, Lucio Miele, Abdul Fauq, Pritam Das, Todd E Golde, Barbara A Osborne. Blood 2008
Jeremy B Samon, Ameya Champhekar, Lisa M Minter, Janice C Telfer, Lucio Miele, Abdul Fauq, Pritam Das, Todd E Golde, Barbara A Osborne. Blood 2008
8
Acetylation controls Notch3 stability and function in T-cell leukemia.
R Palermo, S Checquolo, A Giovenco, P Grazioli, V Kumar, A F Campese, A Giorgi, M Napolitano, G Canettieri, G Ferrara,[...]. Oncogene 2012
R Palermo, S Checquolo, A Giovenco, P Grazioli, V Kumar, A F Campese, A Giorgi, M Napolitano, G Canettieri, G Ferrara,[...]. Oncogene 2012
19
Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
V Agnusdei, S Minuzzo, C Frasson, A Grassi, F Axelrod, S Satyal, A Gurney, T Hoey, E Seganfreddo, G Basso,[...]. Leukemia 2014
9
Therapeutic modulation of Notch signalling--are we there yet?
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
Emma R Andersson, Urban Lendahl. Nat Rev Drug Discov 2014
8
Targeting Notch signaling with a Notch2/Notch3 antagonist (tarextumab) inhibits tumor growth and decreases tumor-initiating cell frequency.
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
Wan-Ching Yen, Marcus M Fischer, Fumiko Axelrod, Christopher Bond, Jennifer Cain, Belinda Cancilla, William R Henner, Rene Meisner, Aaron Sato, Jalpa Shah,[...]. Clin Cancer Res 2015
8
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.