A citation-based method for searching scientific literature

Jung-whan Kim, Irina Tchernyshyov, Gregg L Semenza, Chi V Dang. Cell Metab 2006
Times Cited: 2172







List of co-cited articles
988 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption.
Ioanna Papandreou, Rob A Cairns, Lucrezia Fontana, Ai Lin Lim, Nicholas C Denko. Cell Metab 2006
27

Understanding the Warburg effect: the metabolic requirements of cell proliferation.
Matthew G Vander Heiden, Lewis C Cantley, Craig B Thompson. Science 2009
19

On the origin of cancer cells.
O WARBURG. Science 1956
15

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.
Oscar R Colegio, Ngoc-Quynh Chu, Alison L Szabo, Thach Chu, Anne Marie Rhebergen, Vikram Jairam, Nika Cyrus, Carolyn E Brokowski, Stephanie C Eisenbarth, Gillian M Phillips,[...]. Nature 2014
11

Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia.
Christian M Metallo, Paulo A Gameiro, Eric L Bell, Katherine R Mattaini, Juanjuan Yang, Karsten Hiller, Christopher M Jewell, Zachary R Johnson, Darrell J Irvine, Leonard Guarente,[...]. Nature 2011
10

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.
N V Iyer, L E Kotch, F Agani, S W Leung, E Laughner, R H Wenger, M Gassmann, J D Gearhart, A M Lawler, A Y Yu,[...]. Genes Dev 1998
10

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation.
Muhammad Zaeem Noman, Giacomo Desantis, Bassam Janji, Meriem Hasmim, Saoussen Karray, Philippe Dessen, Vincenzo Bronte, Salem Chouaib. J Exp Med 2014
909
10

Hypoxia-inducible factors and the response to hypoxic stress.
Amar J Majmundar, Waihay J Wong, M Celeste Simon. Mol Cell 2010
10

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
G L Wang, B H Jiang, E A Rue, G L Semenza. Proc Natl Acad Sci U S A 1995
9

THE METABOLISM OF TUMORS IN THE BODY.
O Warburg, F Wind, E Negelein. J Gen Physiol 1927
9

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression.
Chih-Hao Chang, Jing Qiu, David O'Sullivan, Michael D Buck, Takuro Noguchi, Jonathan D Curtis, Qiongyu Chen, Mariel Gindin, Matthew M Gubin, Gerritje J W van der Windt,[...]. Cell 2015
9

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
9


HIF-1: upstream and downstream of cancer metabolism.
Gregg L Semenza. Curr Opin Genet Dev 2010
812
9

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth.
Sébastien Bonnet, Stephen L Archer, Joan Allalunis-Turner, Alois Haromy, Christian Beaulieu, Richard Thompson, Christopher T Lee, Gary D Lopaschuk, Lakshmi Puttagunta, Sandra Bonnet,[...]. Cancer Cell 2007
9

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.
Anne Le, Charles R Cooper, Arvin M Gouw, Ramani Dinavahi, Anirban Maitra, Lorraine M Deck, Robert E Royer, David L Vander Jagt, Gregg L Semenza, Chi V Dang. Proc Natl Acad Sci U S A 2010
811
8

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1.
Weibo Luo, Hongxia Hu, Ryan Chang, Jun Zhong, Matthew Knabel, Robert O'Meally, Robert N Cole, Akhilesh Pandey, Gregg L Semenza. Cell 2011
801
8

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.
Pearl Lee, Navdeep S Chandel, M Celeste Simon. Nat Rev Mol Cell Biol 2020
132
8

Inhibitory effect of tumor cell-derived lactic acid on human T cells.
Karin Fischer, Petra Hoffmann, Simon Voelkl, Norbert Meidenbauer, Julia Ammer, Matthias Edinger, Eva Gottfried, Sabine Schwarz, Gregor Rothe, Sabine Hoves,[...]. Blood 2007
802
8

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation.
Cheng-Jun Hu, Li-Yi Wang, Lewis A Chodosh, Brian Keith, M Celeste Simon. Mol Cell Biol 2003
913
8

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
Pierre Sonveaux, Frédérique Végran, Thies Schroeder, Melanie C Wergin, Julien Verrax, Zahid N Rabbani, Christophe J De Saedeleer, Kelly M Kennedy, Caroline Diepart, Bénédicte F Jordan,[...]. J Clin Invest 2008
8


Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability.
David R Wise, Patrick S Ward, Jessica E S Shay, Justin R Cross, Joshua J Gruber, Uma M Sachdeva, Jesse M Platt, Raymond G DeMatteo, M Celeste Simon, Craig B Thompson. Proc Natl Acad Sci U S A 2011
620
7

Regulation of cancer cell metabolism.
Rob A Cairns, Isaac S Harris, Tak W Mak. Nat Rev Cancer 2011
7

Tumor-derived lactic acid modulates dendritic cell activation and antigen expression.
Eva Gottfried, Leoni A Kunz-Schughart, Stephanie Ebner, Wolfgang Mueller-Klieser, Sabine Hoves, Reinhard Andreesen, Andreas Mackensen, Marina Kreutz. Blood 2006
323
7


HIF-1alpha is essential for myeloid cell-mediated inflammation.
Thorsten Cramer, Yuji Yamanishi, Björn E Clausen, Irmgard Förster, Rafal Pawlinski, Nigel Mackman, Volker H Haase, Rudolf Jaenisch, Maripat Corr, Victor Nizet,[...]. Cell 2003
7

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.
Ralph J DeBerardinis, Anthony Mancuso, Evgueni Daikhin, Ilana Nissim, Marc Yudkoff, Suzanne Wehrli, Craig B Thompson. Proc Natl Acad Sci U S A 2007
7

The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy.
Barbara Muz, Pilar de la Puente, Feda Azab, Abdel Kareem Azab. Hypoxia (Auckl) 2015
563
7

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells.
Lewis Z Shi, Ruoning Wang, Gonghua Huang, Peter Vogel, Geoffrey Neale, Douglas R Green, Hongbo Chi. J Exp Med 2011
982
7

Akt stimulates aerobic glycolysis in cancer cells.
Rebecca L Elstrom, Daniel E Bauer, Monica Buzzai, Robyn Karnauskas, Marian H Harris, David R Plas, Hongming Zhuang, Ryan M Cinalli, Abass Alavi, Charles M Rudin,[...]. Cancer Res 2004
985
7

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation.
P Jaakkola, D R Mole, Y M Tian, M I Wilson, J Gielbert, S J Gaskell, A von Kriegsheim, H F Hebestreit, M Mukherji, C J Schofield,[...]. Science 2001
7

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing.
M Ivan, K Kondo, H Yang, W Kim, J Valiando, M Ohh, A Salic, J M Asara, W S Lane, W G Kaelin. Science 2001
7

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells.
Ryo Fukuda, Huafeng Zhang, Jung-whan Kim, Larissa Shimoda, Chi V Dang, Gregg L Semenza. Cell 2007
784
7

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
De Huang, Tingting Li, Xinghua Li, Long Zhang, Linchong Sun, Xiaoping He, Xiuying Zhong, Dongya Jia, Libing Song, Gregg L Semenza,[...]. Cell Rep 2014
163
7


Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells.
Thomas McFate, Ahmed Mohyeldin, Huasheng Lu, Jay Thakar, Jeremy Henriques, Nader D Halim, Hong Wu, Michael J Schell, Tsz Mon Tsang, Orla Teahan,[...]. J Biol Chem 2008
240
7


Fundamentals of cancer metabolism.
Ralph J DeBerardinis, Navdeep S Chandel. Sci Adv 2016
979
7


The Warburg Effect: How Does it Benefit Cancer Cells?
Maria V Liberti, Jason W Locasale. Trends Biochem Sci 2016
6

Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release.
Kristina Goetze, Stefan Walenta, Magdalena Ksiazkiewicz, Leoni A Kunz-Schughart, Wolfgang Mueller-Klieser. Int J Oncol 2011
176
6

The Emerging Hallmarks of Cancer Metabolism.
Natalya N Pavlova, Craig B Thompson. Cell Metab 2016
6

Metabolic modulation of glioblastoma with dichloroacetate.
E D Michelakis, G Sutendra, P Dromparis, L Webster, A Haromy, E Niven, C Maguire, T-L Gammer, J R Mackey, D Fulton,[...]. Sci Transl Med 2010
477
6

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.
Heather R Christofk, Matthew G Vander Heiden, Marian H Harris, Arvind Ramanathan, Robert E Gerszten, Ru Wei, Mark D Fleming, Stuart L Schreiber, Lewis C Cantley. Nature 2008
6

Targeting Metabolism for Cancer Therapy.
Alba Luengo, Dan Y Gui, Matthew G Vander Heiden. Cell Chem Biol 2017
295
6

Transcriptional regulation by hypoxia inducible factors.
Veronica L Dengler, Matthew Galbraith, Joaquín M Espinosa. Crit Rev Biochem Mol Biol 2014
287
6

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation.
Ruoning Wang, Christopher P Dillon, Lewis Zhichang Shi, Sandra Milasta, Robert Carter, David Finkelstein, Laura L McCormick, Patrick Fitzgerald, Hongbo Chi, Joshua Munger,[...]. Immunity 2011
6

Advances in Hypoxia-Inducible Factor Biology.
Hani Choudhry, Adrian L Harris. Cell Metab 2018
210
6

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.
Ryan D Michalek, Valerie A Gerriets, Sarah R Jacobs, Andrew N Macintyre, Nancie J MacIver, Emily F Mason, Sarah A Sullivan, Amanda G Nichols, Jeffrey C Rathmell. J Immunol 2011
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.