Janine Hertzog Santos, Joel N Meyer, Bennett Van Houten. Hum Mol Genet 2006
Times Cited: 136
Times Cited: 136
Times Cited
Times Co-cited
Similarity
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
Judith Haendeler, Stefan Dröse, Nicole Büchner, Sascha Jakob, Joachim Altschmied, Christine Goy, Ioakim Spyridopoulos, Andreas M Zeiher, Ulrich Brandt, Stefanie Dimmeler. Arterioscler Thromb Vasc Biol 2009
57
Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress.
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
Shaheda Ahmed, João F Passos, Matthew J Birket, Tina Beckmann, Sebastian Brings, Heiko Peters, Mark A Birch-Machin, Thomas von Zglinicki, Gabriele Saretzki. J Cell Sci 2008
55
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage.
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
Janine Hertzog Santos, Joel N Meyer, Milan Skorvaga, Lois A Annab, Bennett Van Houten. Aging Cell 2004
51
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
Judith Haendeler, Jörg Hoffmann, Ralf P Brandes, Andreas M Zeiher, Stefanie Dimmeler. Mol Cell Biol 2003
33
Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria.
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
Nilesh K Sharma, Aurelio Reyes, Paula Green, Matthieu J Caron, Marcelo G Bonini, Donna M Gordon, Ian J Holt, Janine Hertzog Santos. Nucleic Acids Res 2012
33
Telomere dysfunction induces metabolic and mitochondrial compromise.
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
Ergün Sahin, Simona Colla, Marc Liesa, Javid Moslehi, Florian L Müller, Mira Guo, Marcus Cooper, Darrell Kotton, Attila J Fabian, Carl Walkey,[...]. Nature 2011
32
hTERT overexpression alleviates intracellular ROS production, improves mitochondrial function, and inhibits ROS-mediated apoptosis in cancer cells.
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
Inthrani R Indran, Manoor P Hande, Shazib Pervaiz. Cancer Res 2011
32
Telomerase modulates Wnt signalling by association with target gene chromatin.
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
Jae-Il Park, Andrew S Venteicher, Ji Yeon Hong, Jinkuk Choi, Sohee Jun, Marina Shkreli, Woody Chang, Zhaojing Meng, Peggie Cheung, Hong Ji,[...]. Nature 2009
30
An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
Yoshiko Maida, Mami Yasukawa, Miho Furuuchi, Timo Lassmann, Richard Possemato, Naoko Okamoto, Vivi Kasim, Yoshihide Hayashizaki, William C Hahn, Kenkichi Masutomi. Nature 2009
25
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
Kenkichi Masutomi, Richard Possemato, Judy M Y Wong, Jennifer L Currier, Zuzana Tothova, Judith B Manola, Shridar Ganesan, Peter M Lansdorp, Kathleen Collins, William C Hahn. Proc Natl Acad Sci U S A 2005
23
A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction.
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
Olga A Kovalenko, Matthieu J Caron, Perihan Ulema, Carolina Medrano, Andrew P Thomas, Masayuki Kimura, Marcelo G Bonini, Utz Herbig, Janine H Santos. Aging Cell 2010
37
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
Judith Haendeler, Jörg Hoffmann, J Florian Diehl, Mariuca Vasa, Ioakim Spyridopoulos, Andreas M Zeiher, Stefanie Dimmeler. Circ Res 2004
22
Specific association of human telomerase activity with immortal cells and cancer.
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
N W Kim, M A Piatyszek, K R Prowse, C B Harley, M D West, P L Ho, G M Coviello, W E Wright, S L Weinrich, J W Shay. Science 1994
19
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
C W Greider, E H Blackburn. Cell 1985
C W Greider, E H Blackburn. Cell 1985
19
Conditional telomerase induction causes proliferation of hair follicle stem cells.
Kavita Y Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I Tennen, Estee Wang, Maja K Artandi, Anthony E Oro, Steven E Artandi. Nature 2005
Kavita Y Sarin, Peggie Cheung, Daniel Gilison, Eunice Lee, Ruth I Tennen, Estee Wang, Maja K Artandi, Anthony E Oro, Steven E Artandi. Nature 2005
19
Extension of life-span by introduction of telomerase into normal human cells.
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
A G Bodnar, M Ouellette, M Frolkis, S E Holt, C P Chiu, G B Morin, C B Harley, J W Shay, S Lichtsteiner, W E Wright. Science 1998
18
Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent.
Nicole Büchner, Tim-Christian Zschauer, Margarete Lukosz, Joachim Altschmied, Judith Haendeler. Exp Gerontol 2010
Nicole Büchner, Tim-Christian Zschauer, Margarete Lukosz, Joachim Altschmied, Judith Haendeler. Exp Gerontol 2010
51
Mitochondrial telomerase protects cancer cells from nuclear DNA damage and apoptosis.
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
Chatchawan Singhapol, Deepali Pal, Rafal Czapiewski, Mahendar Porika, Glyn Nelson, Gabriele C Saretzki. PLoS One 2013
18
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation.
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
Laura L Smith, Hilary A Coller, James M Roberts. Nat Cell Biol 2003
17
16
TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.
Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah,[...]. PLoS Genet 2008
Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah,[...]. PLoS Genet 2008
16
16
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins.
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
Paula Martínez, María A Blasco. Nat Rev Cancer 2011
16
TERT promotes cellular and organismal survival independently of telomerase activity.
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
J Lee, Y H Sung, C Cheong, Y S Choi, H K Jeon, W Sun, W C Hahn, F Ishikawa, H-W Lee. Oncogene 2008
14
14
Shelterin: the protein complex that shapes and safeguards human telomeres.
Titia de Lange. Genes Dev 2005
Titia de Lange. Genes Dev 2005
14
Telomerase directly regulates NF-κB-dependent transcription.
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
Arkasubhra Ghosh, Gaye Saginc, Shi Chi Leow, Ekta Khattar, Eun Myong Shin, Ting Dong Yan, Marc Wong, Zhizhuo Zhang, Guoliang Li, Wing-Kin Sung,[...]. Nat Cell Biol 2012
14
Telomeres shorten during ageing of human fibroblasts.
C B Harley, A B Futcher, C W Greider. Nature 1990
C B Harley, A B Futcher, C W Greider. Nature 1990
13
Protein composition of catalytically active human telomerase from immortal cells.
Scott B Cohen, Mark E Graham, George O Lovrecz, Nicolai Bache, Phillip J Robinson, Roger R Reddel. Science 2007
Scott B Cohen, Mark E Graham, George O Lovrecz, Nicolai Bache, Phillip J Robinson, Roger R Reddel. Science 2007
13
Involvement of hTERT in apoptosis induced by interference with Bcl-2 expression and function.
D Del Bufalo, A Rizzo, D Trisciuoglio, G Cardinali, M R Torrisi, U Zangemeister-Wittke, G Zupi, A Biroccio. Cell Death Differ 2005
D Del Bufalo, A Rizzo, D Trisciuoglio, G Cardinali, M R Torrisi, U Zangemeister-Wittke, G Zupi, A Biroccio. Cell Death Differ 2005
12
Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.
Sascha Jakob, Peter Schroeder, Margarete Lukosz, Nicole Büchner, Ioakim Spyridopoulos, Joachim Altschmied, Judith Haendeler. J Biol Chem 2008
Sascha Jakob, Peter Schroeder, Margarete Lukosz, Nicole Büchner, Ioakim Spyridopoulos, Joachim Altschmied, Judith Haendeler. J Biol Chem 2008
18
The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis.
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
Imke Listerman, Jie Sun, Francesca S Gazzaniga, Jason L Lukas, Elizabeth H Blackburn. Cancer Res 2013
12
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit.
S S Kang, T Kwon, D Y Kwon, S I Do. J Biol Chem 1999
S S Kang, T Kwon, D Y Kwon, S I Do. J Biol Chem 1999
11
Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation.
Judith Haendeler, Jörg Hoffmann, Sandy Rahman, Andreas M Zeiher, Stefanie Dimmeler. FEBS Lett 2003
Judith Haendeler, Jörg Hoffmann, Sandy Rahman, Andreas M Zeiher, Stefanie Dimmeler. FEBS Lett 2003
11
Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells.
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
Katrin Hoffmeyer, Angelo Raggioli, Stefan Rudloff, Roman Anton, Andreas Hierholzer, Ignacio Del Valle, Kerstin Hein, Riana Vogt, Rolf Kemler. Science 2012
11
Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria.
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
Ilaria Chiodi, Chiara Mondello. Front Oncol 2012
14
Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein.
Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C Munshi, Kenneth C Anderson. Cancer Res 2003
Masaharu Akiyama, Teru Hideshima, Toshiaki Hayashi, Yu-Tzu Tai, Constantine S Mitsiades, Nicholas Mitsiades, Dharminder Chauhan, Paul Richardson, Nikhil C Munshi, Kenneth C Anderson. Cancer Res 2003
10
hTERT associates with human telomeres and enhances genomic stability and DNA repair.
Girdhar G Sharma, Arun Gupta, Huichen Wang, Harry Scherthan, Sonu Dhar, Varsha Gandhi, George Iliakis, Jerry W Shay, Charles S H Young, Tej K Pandita. Oncogene 2003
Girdhar G Sharma, Arun Gupta, Huichen Wang, Harry Scherthan, Sonu Dhar, Varsha Gandhi, George Iliakis, Jerry W Shay, Charles S H Young, Tej K Pandita. Oncogene 2003
10
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
C Massard, Y Zermati, A-L Pauleau, N Larochette, D Métivier, L Sabatier, G Kroemer, J-C Soria. Oncogene 2006
C Massard, Y Zermati, A-L Pauleau, N Larochette, D Métivier, L Sabatier, G Kroemer, J-C Soria. Oncogene 2006
10
Human telomerase and its regulation.
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
Yu-Sheng Cong, Woodring E Wright, Jerry W Shay. Microbiol Mol Biol Rev 2002
10
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism.
Sheila A Stewart, William C Hahn, Benjamin F O'Connor, Elisa N Banner, Ante S Lundberg, Poonam Modha, Hana Mizuno, Mary W Brooks, Mark Fleming, Drazen B Zimonjic,[...]. Proc Natl Acad Sci U S A 2002
Sheila A Stewart, William C Hahn, Benjamin F O'Connor, Elisa N Banner, Ante S Lundberg, Poonam Modha, Hana Mizuno, Mary W Brooks, Mark Fleming, Drazen B Zimonjic,[...]. Proc Natl Acad Sci U S A 2002
10
Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase.
Margaret A Strong, Sofia L Vidal-Cardenas, Baktiar Karim, Huimin Yu, Nini Guo, Carol W Greider. Mol Cell Biol 2011
Margaret A Strong, Sofia L Vidal-Cardenas, Baktiar Karim, Huimin Yu, Nini Guo, Carol W Greider. Mol Cell Biol 2011
10
Separation of telomerase functions by reverse genetics.
Shibani Mukherjee, Eduardo J Firpo, Yang Wang, James M Roberts. Proc Natl Acad Sci U S A 2011
Shibani Mukherjee, Eduardo J Firpo, Yang Wang, James M Roberts. Proc Natl Acad Sci U S A 2011
14
The emerging role of telomerase reverse transcriptase in mitochondrial DNA metabolism.
Donna M Gordon, Janine Hertzog Santos. J Nucleic Acids 2010
Donna M Gordon, Janine Hertzog Santos. J Nucleic Acids 2010
38
Critical Role for Telomerase in the Mechanism of Flow-Mediated Dilation in the Human Microcirculation.
Andreas M Beyer, Julie K Freed, Matthew J Durand, Michael Riedel, Karima Ait-Aissa, Paula Green, Joseph C Hockenberry, R Garret Morgan, Anthony J Donato, Refael Peleg,[...]. Circ Res 2016
Andreas M Beyer, Julie K Freed, Matthew J Durand, Michael Riedel, Karima Ait-Aissa, Paula Green, Joseph C Hockenberry, R Garret Morgan, Anthony J Donato, Refael Peleg,[...]. Circ Res 2016
16
Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis.
Vera Gorbunova, Andrei Seluanov, Olivia M Pereira-Smith. J Biol Chem 2002
Vera Gorbunova, Andrei Seluanov, Olivia M Pereira-Smith. J Biol Chem 2002
9
Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.
Charles Dudognon, Frédéric Pendino, Josette Hillion, Anne Saumet, Michel Lanotte, Evelyne Ségal-Bendirdjian. Oncogene 2004
Charles Dudognon, Frédéric Pendino, Josette Hillion, Anne Saumet, Michel Lanotte, Evelyne Ségal-Bendirdjian. Oncogene 2004
14
Telomerase catalytic subunit homologs from fission yeast and human.
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
T M Nakamura, G B Morin, K B Chapman, S L Weinrich, W H Andrews, J Lingner, C B Harley, T R Cech. Science 1997
9
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.