A citation-based method for searching scientific literature

Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Charles S Hemenway, Bruce C Kone. J Biol Chem 2006
Times Cited: 129







List of co-cited articles
1166 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


hDOT1L links histone methylation to leukemogenesis.
Yuki Okada, Qin Feng, Yihui Lin, Qi Jiang, Yaqiang Li, Vernon M Coffield, Lishan Su, Guoliang Xu, Yi Zhang. Cell 2005
589
56

A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification.
Dorothee Mueller, Christian Bach, Deniz Zeisig, Maria-Paz Garcia-Cuellar, Sara Monroe, Arun Sreekumar, Rong Zhou, Alexey Nesvizhskii, Arul Chinnaiyan, Jay L Hess,[...]. Blood 2007
281
51


H3K79 methylation profiles define murine and human MLL-AF4 leukemias.
Andrei V Krivtsov, Zhaohui Feng, Madeleine E Lemieux, Joerg Faber, Sridhar Vempati, Amit U Sinha, Xiaobo Xia, Jonathan Jesneck, Adrian P Bracken, Lewis B Silverman,[...]. Cancer Cell 2008
390
32

Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha.
Wenzheng Zhang, Xuefeng Xia, Mary Rose Reisenauer, Timo Rieg, Florian Lang, Dietmar Kuhl, Volker Vallon, Bruce C Kone. J Clin Invest 2007
115
31

DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
David J Steger, Martina I Lefterova, Lei Ying, Aaron J Stonestrom, Michael Schupp, David Zhuo, Adam L Vakoc, Ja-Eun Kim, Junjie Chen, Mitchell A Lazar,[...]. Mol Cell Biol 2008
320
30

MLL translocations, histone modifications and leukaemia stem-cell development.
Andrei V Krivtsov, Scott A Armstrong. Nat Rev Cancer 2007
796
29

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Qin Feng, Hengbin Wang, Huck Hui Ng, Hediye Erdjument-Bromage, Paul Tempst, Kevin Struhl, Yi Zhang. Curr Biol 2002
569
29

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Christina R Majer, Christopher J Sneeringer, Jeffrey Song, L Danielle Johnston, Margaret Porter Scott, Jesse J Smith, Yonghong Xiao,[...]. Cancer Cell 2011
644
29

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.
Kathrin M Bernt, Nan Zhu, Amit U Sinha, Sridhar Vempati, Joerg Faber, Andrei V Krivtsov, Zhaohui Feng, Natalie Punt, Amanda Daigle, Lars Bullinger,[...]. Cancer Cell 2011
590
28

A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
Akihiko Yokoyama, Min Lin, Alpana Naresh, Issay Kitabayashi, Michael L Cleary. Cancer Cell 2010
252
27

Dot1p modulates silencing in yeast by methylation of the nucleosome core.
Fred van Leeuwen, Philip R Gafken, Daniel E Gottschling. Cell 2002
611
26

Potent inhibition of DOT1L as treatment of MLL-fusion leukemia.
Scott R Daigle, Edward J Olhava, Carly A Therkelsen, Aravind Basavapathruni, Lei Jin, P Ann Boriack-Sjodin, Christina J Allain, Christine R Klaus, Alejandra Raimondi, Margaret Porter Scott,[...]. Blood 2013
457
26

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
Brendan Jones, Hui Su, Audesh Bhat, Hong Lei, Jeffrey Bajko, Sarah Hevi, Gretchen A Baltus, Shilpa Kadam, Huili Zhai, Reginald Valdez,[...]. PLoS Genet 2008
237
25

Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom).
Man Mohan, Hans-Martin Herz, Yoh-Hei Takahashi, Chengqi Lin, Ka Chun Lai, Ying Zhang, Michael P Washburn, Laurence Florens, Ali Shilatifard. Genes Dev 2010
210
25

MLL targets SET domain methyltransferase activity to Hox gene promoters.
Thomas A Milne, Scott D Briggs, Hugh W Brock, Mary Ellen Martin, Denise Gibbs, C David Allis, Jay L Hess. Mol Cell 2002
786
24

Aldosterone-sensitive repression of ENaCalpha transcription by a histone H3 lysine-79 methyltransferase.
Wenzheng Zhang, Xuefeng Xia, Diana I Jalal, Teresa Kuncewicz, William Xu, Gene D Lesage, Bruce C Kone. Am J Physiol Cell Physiol 2006
50
48

AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia.
Chengqi Lin, Edwin R Smith, Hidehisa Takahashi, Ka Chun Lai, Skylar Martin-Brown, Laurence Florens, Michael P Washburn, Joan W Conaway, Ronald C Conaway, Ali Shilatifard. Mol Cell 2010
397
24

The diverse functions of Dot1 and H3K79 methylation.
Anh Tram Nguyen, Yi Zhang. Genes Dev 2011
366
23

Histone H3 lysine 79 methyltransferase Dot1 is required for immortalization by MLL oncogenes.
Ming-Jin Chang, Hongyu Wu, Nicholas J Achille, Mary Rose Reisenauer, Chau-Wen Chou, Nancy J Zeleznik-Le, Charles S Hemenway, Wenzheng Zhang. Cancer Res 2010
123
22

Misguided transcriptional elongation causes mixed lineage leukemia.
Dorothee Mueller, María-Paz García-Cuéllar, Christian Bach, Sebastian Buhl, Emanuel Maethner, Robert K Slany. PLoS Biol 2009
148
21

AF17 competes with AF9 for binding to Dot1a to up-regulate transcription of epithelial Na+ channel alpha.
Mary Rose Reisenauer, Marc Anderson, Le Huang, Zhijing Zhang, Qiaoling Zhou, Bruce C Kone, Andrew P Morris, Gene D Lesage, Stuart E Dryer, Wenzheng Zhang. J Biol Chem 2009
37
54

DOT1L, the H3K79 methyltransferase, is required for MLL-AF9-mediated leukemogenesis.
Anh Tram Nguyen, Olena Taranova, Jin He, Yi Zhang. Blood 2011
179
20

Identification of high-copy disruptors of telomeric silencing in Saccharomyces cerevisiae.
M S Singer, A Kahana, A J Wolf, L L Meisinger, S E Peterson, C Goggin, M Mahowald, D E Gottschling. Genetics 1998
367
19

Dot1a contains three nuclear localization signals and regulates the epithelial Na+ channel (ENaC) at multiple levels.
Mary Rose Reisenauer, Steven W Wang, Yang Xia, Wenzheng Zhang. Am J Physiol Renal Physiol 2010
33
57

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation.
Tatsuya Nakamura, Toshiki Mori, Shinichiro Tada, Wladyslaw Krajewski, Tanya Rozovskaia, Richard Wassell, Garrett Dubois, Alexander Mazo, Carlo M Croce, Eli Canaani. Mol Cell 2002
552
18

Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation.
Stephanie Y Jo, Eric M Granowicz, Ivan Maillard, Dafydd Thomas, Jay L Hess. Blood 2011
148
18

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia.
Matthew G Guenther, Lee N Lawton, Tatiana Rozovskaia, Garrett M Frampton, Stuart S Levine, Thomas L Volkert, Carlo M Croce, Tatsuya Nakamura, Eli Canaani, Richard A Young. Genes Dev 2008
200
17

Early mammalian erythropoiesis requires the Dot1L methyltransferase.
Yi Feng, Yanping Yang, Manoela M Ortega, Jessica N Copeland, Mingcai Zhang, Jennifer B Jacob, Timothy A Fields, Jay L Vivian, Patrick E Fields. Blood 2010
86
19

Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Wenyu Yu, Emma J Chory, Amy K Wernimont, Wolfram Tempel, Alex Scopton, Alexander Federation, Jason J Marineau, Jun Qi, Dalia Barsyte-Lovejoy, Joanna Yi,[...]. Nat Commun 2012
187
17



MLL fusion partners AF4 and AF9 interact at subnuclear foci.
F Erfurth, C S Hemenway, A C de Erkenez, P H Domer. Leukemia 2004
67
22

Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Debabrata Biswas, Thomas A Milne, Venkatesha Basrur, Jaehoon Kim, Kojo S J Elenitoba-Johnson, C David Allis, Robert G Roeder. Proc Natl Acad Sci U S A 2011
125
15

Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase.
Wenzheng Zhang, Yoshihide Hayashizaki, Bruce C Kone. Biochem J 2004
46
28

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.
Andrei V Krivtsov, David Twomey, Zhaohui Feng, Matthew C Stubbs, Yingzi Wang, Joerg Faber, Jason E Levine, Jing Wang, William C Hahn, D Gary Gilliland,[...]. Nature 2006
13

Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor.
Caroline Ronzaud, Johannes Loffing, Markus Bleich, Norbert Gretz, Hermann-Josef Gröne, Günther Schütz, Stefan Berger. J Am Soc Nephrol 2007
87
14

An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene.
Wenzheng Zhang, Zhiyuan Yu, Hongyu Wu, Lihe Chen, Qun Kong, Bruce C Kone. Am J Physiol Renal Physiol 2013
15
86




High-resolution profiling of histone methylations in the human genome.
Artem Barski, Suresh Cuddapah, Kairong Cui, Tae-Young Roh, Dustin E Schones, Zhibin Wang, Gang Wei, Iouri Chepelev, Keji Zhao. Cell 2007
12

Af17 deficiency increases sodium excretion and decreases blood pressure.
Lihe Chen, Hongyu Wu, Oleh M Pochynyuk, Mary Rose Reisenauer, Zhijing Zhang, Le Huang, Oleg Leonidovych Zaika, Mykola Mamenko, Weiru Zhang, Qiaoling Zhou,[...]. J Am Soc Nephrol 2011
21
57

Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation.
Huck Hui Ng, David N Ciccone, Katrina B Morshead, Marjorie A Oettinger, Kevin Struhl. Proc Natl Acad Sci U S A 2003
235
11

The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin.
Deniz T Zeisig, Claudia B Bittner, Bernd B Zeisig, Maria-Paz García-Cuéllar, Jay L Hess, Robert K Slany. Oncogene 2005
89
12

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Scott A Armstrong, Jane E Staunton, Lewis B Silverman, Rob Pieters, Monique L den Boer, Mark D Minden, Stephen E Sallan, Eric S Lander, Todd R Golub, Stanley J Korsmeyer. Nat Genet 2002
11

The mixed lineage leukemia fusion partner AF9 binds specific isoforms of the BCL-6 corepressor.
R Sathish Srinivasan, Andrea C de Erkenez, Charles S Hemenway. Oncogene 2003
61
18

Characterization of the DOT1L network: implications of diverse roles for DOT1L.
Geunyeong Park, Zihua Gong, Junjie Chen, Ja-Eun Kim. Protein J 2010
39
28

Abrogation of MLL-AF10 and CALM-AF10-mediated transformation through genetic inactivation or pharmacological inhibition of the H3K79 methyltransferase Dot1l.
L Chen, A J Deshpande, D Banka, K M Bernt, S Dias, C Buske, E J Olhava, S R Daigle, V M Richon, R M Pollock,[...]. Leukemia 2013
100
11

Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L.
Aravind Basavapathruni, Lei Jin, Scott R Daigle, Christina R A Majer, Carly A Therkelsen, Tim J Wigle, Kevin W Kuntz, Richard Chesworth, Roy M Pollock, Margaret P Scott,[...]. Chem Biol Drug Des 2012
96
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.