A citation-based method for searching scientific literature

Toyoaki Tenzen, Benjamin L Allen, Francesca Cole, Jong-Sun Kang, Robert S Krauss, Andrew P McMahon. Dev Cell 2006
Times Cited: 273







List of co-cited articles
1235 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.
Benjamin L Allen, Jane Y Song, Luisa Izzi, Irene W Althaus, Jong-Sun Kang, Frédéric Charron, Robert S Krauss, Andrew P McMahon. Dev Cell 2011
197
49


Gas1 extends the range of Hedgehog action by facilitating its signaling.
David C Martinelli, Chen-Ming Fan. Genes Dev 2007
155
39


Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation.
Luisa Izzi, Martin Lévesque, Steves Morin, Dominique Laniel, Brian C Wilkes, Frédéric Mille, Robert S Krauss, Andrew P McMahon, Benjamin L Allen, Frédéric Charron. Dev Cell 2011
171
36

The mechanisms of Hedgehog signalling and its roles in development and disease.
James Briscoe, Pascal P Thérond. Nat Rev Mol Cell Biol 2013
35

Boc is a receptor for sonic hedgehog in the guidance of commissural axons.
Ami Okada, Frédéric Charron, Steves Morin, David S Shin, Karen Wong, Pierre J Fabre, Marc Tessier-Lavigne, Susan K McConnell. Nature 2006
216
35



Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors.
Gyu-Un Bae, Sabina Domené, Erich Roessler, Karen Schachter, Jong-Sun Kang, Maximilian Muenke, Robert S Krauss. Am J Hum Genet 2011
95
25

Biochemical evidence that patched is the Hedgehog receptor.
V Marigo, R A Davey, Y Zuo, J M Cunningham, C J Tabin. Nature 1996
672
24


Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Hanna Tukachinsky, Ryan P Kuzmickas, Cindy Y Jao, Jing Liu, Adrian Salic. Cell Rep 2012
132
21

Vertebrate Smoothened functions at the primary cilium.
Kevin C Corbit, Pia Aanstad, Veena Singla, Andrew R Norman, Didier Y R Stainier, Jeremy F Reiter. Nature 2005
21


Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function.
C Chiang, Y Litingtung, E Lee, K E Young, J L Corden, H Westphal, P A Beachy. Nature 1996
19

The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
Jason S McLellan, Xiaoyan Zheng, Glenn Hauk, Rodolfo Ghirlando, Philip A Beachy, Daniel J Leahy. Nature 2008
116
19

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.
D M Stone, M Hynes, M Armanini, T A Swanson, Q Gu, R L Johnson, M P Scott, D Pennica, A Goddard, H Phillips,[...]. Nature 1996
904
19

BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation.
Jong-Sun Kang, Philip J Mulieri, Yulan Hu, Lavinia Taliana, Robert S Krauss. EMBO J 2002
116
19

Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.
Y Echelard, D J Epstein, B St-Jacques, L Shen, J Mohler, J A McMahon, A P McMahon. Cell 1993
18

Patched1 regulates hedgehog signaling at the primary cilium.
Rajat Rohatgi, Ljiljana Milenkovic, Matthew P Scott. Science 2007
989
18


Patched acts catalytically to suppress the activity of Smoothened.
J Taipale, M K Cooper, T Maiti, P A Beachy. Nature 2002
588
17

Mutations affecting segment number and polarity in Drosophila.
C Nüsslein-Volhard, E Wieschaus. Nature 1980
17

Identification of a palmitic acid-modified form of human Sonic hedgehog.
R B Pepinsky, C Zeng, D Wen, P Rayhorn, D P Baker, K P Williams, S A Bixler, C M Ambrose, E A Garber, K Miatkowski,[...]. J Biol Chem 1998
538
17

Altered neural cell fates and medulloblastoma in mouse patched mutants.
L V Goodrich, L Milenković, K M Higgins, M P Scott. Science 1997
15

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.
Jessica Svärd, Karin Heby-Henricson, Madelen Persson-Lek, Björn Rozell, Matthias Lauth, Asa Bergström, Johan Ericson, Rune Toftgård, Stephan Teglund. Dev Cell 2006
358
15


Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog.
Maisa Seppala, Michael J Depew, David C Martinelli, Chen-Ming Fan, Paul T Sharpe, Martyn T Cobourne. J Clin Invest 2007
100
15

Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Pengxiang Huang, Daniel Nedelcu, Miyako Watanabe, Cindy Jao, Youngchang Kim, Jing Liu, Adrian Salic. Cell 2016
209
15


Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched.
Yong Ma, Alfrun Erkner, Ruoyu Gong, Shenqin Yao, Jussi Taipale, Konrad Basler, Philip A Beachy. Cell 2002
223
14

Boc modifies the holoprosencephaly spectrum of Cdo mutant mice.
Wei Zhang, Mingi Hong, Gyu-un Bae, Jong-Sun Kang, Robert S Krauss. Dis Model Mech 2011
50
28


Interactions between Hedgehog proteins and their binding partners come into view.
Philip A Beachy, Sarah G Hymowitz, Robert A Lazarus, Daniel J Leahy, Christian Siebold. Genes Dev 2010
135
14

Hedgehog: functions and mechanisms.
Markku Varjosalo, Jussi Taipale. Genes Dev 2008
856
14


Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.
Giovanni Luchetti, Ria Sircar, Jennifer H Kong, Sigrid Nachtergaele, Andreas Sagner, Eamon Fx Byrne, Douglas F Covey, Christian Siebold, Rajat Rohatgi. Elife 2016
141
14

Developmental roles and clinical significance of hedgehog signaling.
Andrew P McMahon, Philip W Ingham, Clifford J Tabin. Curr Top Dev Biol 2003
677
13

Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning.
Alexander M Holtz, Kevin A Peterson, Yuichi Nishi, Steves Morin, Jane Y Song, Frédéric Charron, Andrew P McMahon, Benjamin L Allen. Development 2013
57
22

CDO: an oncogene-, serum-, and anchorage-regulated member of the Ig/fibronectin type III repeat family.
J S Kang, M Gao, J L Feinleib, P D Cotter, S N Guadagno, R S Krauss. J Cell Biol 1997
78
16

The primary cilium: a signalling centre during vertebrate development.
Sarah C Goetz, Kathryn V Anderson. Nat Rev Genet 2010
13

Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form.
Adrian Creanga, Thomas D Glenn, Randall K Mann, Adam M Saunders, William S Talbot, Philip A Beachy. Genes Dev 2012
93
12

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins.
Eric W Humke, Karolin V Dorn, Ljiljana Milenkovic, Matthew P Scott, Rajat Rohatgi. Genes Dev 2010
314
12

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.
H L Park, C Bai, K A Platt, M P Matise, A Beeghly, C C Hui, M Nakashima, A L Joyner. Development 2000
517
12

Identification of Hedgehog pathway components by RNAi in Drosophila cultured cells.
Lawrence Lum, Shenqin Yao, Brian Mozer, Alessandra Rovescalli, Doris Von Kessler, Marshall Nirenberg, Philip A Beachy. Science 2003
412
12

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours.
David M Berman, Sunil S Karhadkar, Anirban Maitra, Rocio Montes De Oca, Meg R Gerstenblith, Kimberly Briggs, Antony R Parker, Yutaka Shimada, James R Eshleman, D Neil Watkins,[...]. Nature 2003
12

A freely diffusible form of Sonic hedgehog mediates long-range signalling.
X Zeng, J A Goetz, L M Suber, W J Scott, C M Schreiner, D J Robbins. Nature 2001
343
11


Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation.
Yong Pan, Chunyang Brian Bai, Alexandra L Joyner, Baolin Wang. Mol Cell Biol 2006
390
11


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.