Elena Bonora, Anna Maria Porcelli, Giuseppe Gasparre, Annalisa Biondi, Anna Ghelli, Valerio Carelli, Alessandra Baracca, Giovanni Tallini, Andrea Martinuzzi, Giorgio Lenaz, Michela Rugolo, Giovanni Romeo. Cancer Res 2006
Times Cited: 168
Times Cited: 168
Times Cited
Times Co-cited
Similarity
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.
Giuseppe Gasparre, Anna Maria Porcelli, Elena Bonora, Lucia Fiammetta Pennisi, Matteo Toller, Luisa Iommarini, Anna Ghelli, Massimo Moretti, Christine M Betts, Giuseppe Nicola Martinelli,[...]. Proc Natl Acad Sci U S A 2007
Giuseppe Gasparre, Anna Maria Porcelli, Elena Bonora, Lucia Fiammetta Pennisi, Matteo Toller, Luisa Iommarini, Anna Ghelli, Massimo Moretti, Christine M Betts, Giuseppe Nicola Martinelli,[...]. Proc Natl Acad Sci U S A 2007
44
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.
Anna Maria Porcelli, Anna Ghelli, Claudio Ceccarelli, Martin Lang, Giovanna Cenacchi, Mariantonietta Capristo, Lucia Fiammetta Pennisi, Isabella Morra, Enrica Ciccarelli, Antonio Melcarne,[...]. Hum Mol Genet 2010
Anna Maria Porcelli, Anna Ghelli, Claudio Ceccarelli, Martin Lang, Giovanna Cenacchi, Mariantonietta Capristo, Lucia Fiammetta Pennisi, Isabella Morra, Enrica Ciccarelli, Antonio Melcarne,[...]. Hum Mol Genet 2010
24
Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.
V Máximo, T Botelho, J Capela, P Soares, J Lima, A Taveira, T Amaro, A P Barbosa, A Preto, H R Harach,[...]. Br J Cancer 2005
V Máximo, T Botelho, J Capela, P Soares, J Lima, A Taveira, T Amaro, A P Barbosa, A Preto, H R Harach,[...]. Br J Cancer 2005
20
Loss of complex I due to mitochondrial DNA mutations in renal oncocytoma.
Johannes A Mayr, David Meierhofer, Franz Zimmermann, Rene Feichtinger, Christian Kögler, Manfred Ratschek, Nikolaus Schmeller, Wolfgang Sperl, Barbara Kofler. Clin Cancer Res 2008
Johannes A Mayr, David Meierhofer, Franz Zimmermann, Rene Feichtinger, Christian Kögler, Manfred Ratschek, Nikolaus Schmeller, Wolfgang Sperl, Barbara Kofler. Clin Cancer Res 2008
19
Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
Giuseppe Gasparre, Eric Hervouet, Elodie de Laplanche, Jocelyne Demont, Lucia Fiammetta Pennisi, Marc Colombel, Florence Mège-Lechevallier, Jean-Yves Scoazec, Elena Bonora, Roel Smeets,[...]. Hum Mol Genet 2008
Giuseppe Gasparre, Eric Hervouet, Elodie de Laplanche, Jocelyne Demont, Lucia Fiammetta Pennisi, Marc Colombel, Florence Mège-Lechevallier, Jean-Yves Scoazec, Elena Bonora, Roel Smeets,[...]. Hum Mol Genet 2008
19
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
Kaori Ishikawa, Keizo Takenaga, Miho Akimoto, Nobuko Koshikawa, Aya Yamaguchi, Hirotake Imanishi, Kazuto Nakada, Yoshio Honma, Jun-Ichi Hayashi. Science 2008
18
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.
Giuseppe Gasparre, Ivana Kurelac, Mariantonietta Capristo, Luisa Iommarini, Anna Ghelli, Claudio Ceccarelli, Giordano Nicoletti, Patrizia Nanni, Carla De Giovanni, Katia Scotlandi,[...]. Cancer Res 2011
Giuseppe Gasparre, Ivana Kurelac, Mariantonietta Capristo, Luisa Iommarini, Anna Ghelli, Claudio Ceccarelli, Giordano Nicoletti, Patrizia Nanni, Carla De Giovanni, Katia Scotlandi,[...]. Cancer Res 2011
22
mtDNA mutations increase tumorigenicity in prostate cancer.
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
John A Petros, Amanda K Baumann, Eduardo Ruiz-Pesini, Mahul B Amin, Carrie Qi Sun, John Hall, SoDug Lim, Muta M Issa, W Dana Flanders, Seyed H Hosseini,[...]. Proc Natl Acad Sci U S A 2005
15
Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.
Raj K Gopal, Kirsten Kübler, Sarah E Calvo, Paz Polak, Dimitri Livitz, Daniel Rosebrock, Peter M Sadow, Braidie Campbell, Samuel E Donovan, Salma Amin,[...]. Cancer Cell 2018
Raj K Gopal, Kirsten Kübler, Sarah E Calvo, Paz Polak, Dimitri Livitz, Daniel Rosebrock, Peter M Sadow, Braidie Campbell, Samuel E Donovan, Salma Amin,[...]. Cancer Cell 2018
15
Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.
Valdemar Máximo, Paula Soares, Jorge Lima, José Cameselle-Teijeiro, Manuel Sobrinho-Simões. Am J Pathol 2002
Valdemar Máximo, Paula Soares, Jorge Lima, José Cameselle-Teijeiro, Manuel Sobrinho-Simões. Am J Pathol 2002
14
Mitochondrial complex I is deficient in renal oncocytomas.
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
Helene Simonnet, Jocelyne Demont, Kathy Pfeiffer, Leila Guenaneche, Raymonde Bouvier, Ulrich Brandt, Hermann Schagger, Catherine Godinot. Carcinogenesis 2003
15
Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy.
Ian Ganly, Julio Ricarte Filho, Stephanie Eng, Ronald Ghossein, Luc G T Morris, Yupu Liang, Nicholas Socci, Kasthuri Kannan, Qianxing Mo, James A Fagin,[...]. J Clin Endocrinol Metab 2013
Ian Ganly, Julio Ricarte Filho, Stephanie Eng, Ronald Ghossein, Luc G T Morris, Yupu Liang, Nicholas Socci, Kasthuri Kannan, Qianxing Mo, James A Fagin,[...]. J Clin Endocrinol Metab 2013
13
A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis.
Jeong Soon Park, Lokendra Kumar Sharma, Hongzhi Li, Ruihua Xiang, Deborah Holstein, Jun Wu, James Lechleiter, Susan L Naylor, Janice J Deng, Jianxin Lu,[...]. Hum Mol Genet 2009
Jeong Soon Park, Lokendra Kumar Sharma, Hongzhi Li, Ruihua Xiang, Deborah Holstein, Jun Wu, James Lechleiter, Susan L Naylor, Janice J Deng, Jianxin Lu,[...]. Hum Mol Genet 2009
12
Defective mitochondrial ATP synthesis in oxyphilic thyroid tumors.
F Savagner, B Franc, S Guyetant, P Rodien, P Reynier, Y Malthiery. J Clin Endocrinol Metab 2001
F Savagner, B Franc, S Guyetant, P Rodien, P Reynier, Y Malthiery. J Clin Endocrinol Metab 2001
15
Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes.
Ian Ganly, Vladimir Makarov, Shyamprasad Deraje, YiYu Dong, Ed Reznik, Venkatraman Seshan, Gouri Nanjangud, Stephanie Eng, Promita Bose, Fengshen Kuo,[...]. Cancer Cell 2018
Ian Ganly, Vladimir Makarov, Shyamprasad Deraje, YiYu Dong, Ed Reznik, Venkatraman Seshan, Gouri Nanjangud, Stephanie Eng, Promita Bose, Fengshen Kuo,[...]. Cancer Cell 2018
12
Learning from oncocytic tumors: Why choose inefficient mitochondria?
Giuseppe Gasparre, Giovanni Romeo, Michela Rugolo, Anna Maria Porcelli. Biochim Biophys Acta 2011
Giuseppe Gasparre, Giovanni Romeo, Michela Rugolo, Anna Maria Porcelli. Biochim Biophys Acta 2011
12
Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors.
Luísa Pereira, Pedro Soares, Valdemar Máximo, David C Samuels. BMC Cancer 2012
Luísa Pereira, Pedro Soares, Valdemar Máximo, David C Samuels. BMC Cancer 2012
18
Spectrum of somatic mitochondrial mutations in five cancers.
Tatianna C Larman, Steven R DePalma, Angela G Hadjipanayis, Alexei Protopopov, Jianhua Zhang, Stacey B Gabriel, Lynda Chin, Christine E Seidman, Raju Kucherlapati, J G Seidman. Proc Natl Acad Sci U S A 2012
Tatianna C Larman, Steven R DePalma, Angela G Hadjipanayis, Alexei Protopopov, Jianhua Zhang, Stacey B Gabriel, Lynda Chin, Christine E Seidman, Raju Kucherlapati, J G Seidman. Proc Natl Acad Sci U S A 2012
11
Genome haploidisation with chromosome 7 retention in oncocytic follicular thyroid carcinoma.
Willem E Corver, Dina Ruano, Karin Weijers, Wietske C E den Hartog, Merlijn P van Nieuwenhuizen, Noel de Miranda, Ronald van Eijk, Anneke Middeldorp, Ekaterina S Jordanova, Jan Oosting,[...]. PLoS One 2012
Willem E Corver, Dina Ruano, Karin Weijers, Wietske C E den Hartog, Merlijn P van Nieuwenhuizen, Noel de Miranda, Ronald van Eijk, Anneke Middeldorp, Ekaterina S Jordanova, Jan Oosting,[...]. PLoS One 2012
25
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien,[...]. Elife 2014
Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien,[...]. Elife 2014
11
Lack of complex I is associated with oncocytic thyroid tumours.
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
F A Zimmermann, J A Mayr, D Neureiter, R Feichtinger, B Alinger, N D Jones, W Eder, W Sperl, B Kofler. Br J Cancer 2009
22
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
Giuseppe Gasparre, Luisa Iommarini, Anna Maria Porcelli, Martin Lang, Gian Gaetano Ferri, Ivana Kurelac, Roberta Zuntini, Elisa Mariani, Lucia Fiammetta Pennisi, Ernesto Pasquini,[...]. Hum Mutat 2009
Giuseppe Gasparre, Luisa Iommarini, Anna Maria Porcelli, Martin Lang, Gian Gaetano Ferri, Ivana Kurelac, Roberta Zuntini, Elisa Mariani, Lucia Fiammetta Pennisi, Ernesto Pasquini,[...]. Hum Mutat 2009
26
Low mitochondrial respiratory chain content correlates with tumor aggressiveness in renal cell carcinoma.
Hélène Simonnet, Nathalie Alazard, Kathy Pfeiffer, Catherine Gallou, Christophe Béroud, Jocelyne Demont, Raymonde Bouvier, Hermann Schägger, Catherine Godinot. Carcinogenesis 2002
Hélène Simonnet, Nathalie Alazard, Kathy Pfeiffer, Catherine Gallou, Christophe Béroud, Jocelyne Demont, Raymonde Bouvier, Hermann Schägger, Catherine Godinot. Carcinogenesis 2002
10
The biology and the genetics of Hurthle cell tumors of the thyroid.
Valdemar Máximo, Jorge Lima, Hugo Prazeres, Paula Soares, Manuel Sobrinho-Simões. Endocr Relat Cancer 2012
Valdemar Máximo, Jorge Lima, Hugo Prazeres, Paula Soares, Manuel Sobrinho-Simões. Endocr Relat Cancer 2012
21
Mitochondrial DNA 'common' deletion in Hürthle cell lesions of the thyroid.
V Máximo, M Sobrinho-Simões. J Pathol 2000
V Máximo, M Sobrinho-Simões. J Pathol 2000
22
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells.
Yiping He, Jian Wu, Devin C Dressman, Christine Iacobuzio-Donahue, Sanford D Markowitz, Victor E Velculescu, Luis A Diaz, Kenneth W Kinzler, Bert Vogelstein, Nickolas Papadopoulos. Nature 2010
Yiping He, Jian Wu, Devin C Dressman, Christine Iacobuzio-Donahue, Sanford D Markowitz, Victor E Velculescu, Luis A Diaz, Kenneth W Kinzler, Bert Vogelstein, Nickolas Papadopoulos. Nature 2010
9
Respiratory chain complex I is a mitochondrial tumor suppressor of oncocytic tumors.
Franz A Zimmermann, Johannes A Mayr, Rene Feichtinger, Daniel Neureiter, Roman Lechner, Christian Koegler, Manfred Ratschek, Husic Rusmir, Karine Sargsyan, Wolfgang Sperl,[...]. Front Biosci (Elite Ed) 2011
Franz A Zimmermann, Johannes A Mayr, Rene Feichtinger, Daniel Neureiter, Roman Lechner, Christian Koegler, Manfred Ratschek, Husic Rusmir, Karine Sargsyan, Wolfgang Sperl,[...]. Front Biosci (Elite Ed) 2011
23
Establishment of a highly differentiated thyroid cancer cell line of Hürthle cell origin.
A Zielke, S Tezelman, G H Jossart, M Wong, A E Siperstein, Q Y Duh, O H Clark. Thyroid 1998
A Zielke, S Tezelman, G H Jossart, M Wong, A E Siperstein, Q Y Duh, O H Clark. Thyroid 1998
14
Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation.
Lokendra Kumar Sharma, Hezhi Fang, Jiangtao Liu, Rasika Vartak, Janice Deng, Yidong Bai. Hum Mol Genet 2011
Lokendra Kumar Sharma, Hezhi Fang, Jiangtao Liu, Rasika Vartak, Janice Deng, Yidong Bai. Hum Mol Genet 2011
9
Human mitochondrial DNA: roles of inherited and somatic mutations.
Eric A Schon, Salvatore DiMauro, Michio Hirano. Nat Rev Genet 2012
Eric A Schon, Salvatore DiMauro, Michio Hirano. Nat Rev Genet 2012
9
Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis.
Yujiro Shidara, Kumi Yamagata, Takashi Kanamori, Kazutoshi Nakano, Jennifer Q Kwong, Giovanni Manfredi, Hideaki Oda, Shigeo Ohta. Cancer Res 2005
Yujiro Shidara, Kumi Yamagata, Takashi Kanamori, Kazutoshi Nakano, Jennifer Q Kwong, Giovanni Manfredi, Hideaki Oda, Shigeo Ohta. Cancer Res 2005
8
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels.
Anna Maria Porcelli, Alessia Angelin, Anna Ghelli, Elisa Mariani, Andrea Martinuzzi, Valerio Carelli, Valeria Petronilli, Paolo Bernardi, Michela Rugolo. J Biol Chem 2009
Anna Maria Porcelli, Alessia Angelin, Anna Ghelli, Elisa Mariani, Andrea Martinuzzi, Valerio Carelli, Valeria Petronilli, Paolo Bernardi, Michela Rugolo. J Biol Chem 2009
10
Mitochondrial activities of a cell line derived from thyroid Hürthle cell tumors.
Karmen Stankov, Annalisa Biondi, Marilena D'Aurelio, Giuseppe Gasparre, Anna Falasca, Giovanni Romeo, Giorgio Lenaz. Thyroid 2006
Karmen Stankov, Annalisa Biondi, Marilena D'Aurelio, Giuseppe Gasparre, Anna Falasca, Giovanni Romeo, Giorgio Lenaz. Thyroid 2006
40
Oncocytes, oxyphils, Hürthle, and Askanazy cells: morphological and molecular features of oncocytic thyroid nodules.
Ozgur Mete, Sylvia L Asa. Endocr Pathol 2010
Ozgur Mete, Sylvia L Asa. Endocr Pathol 2010
17
Hashimoto thyroiditis is associated with defects of cytochrome-c oxidase in oxyphil Askanazy cells and with the common deletion (4,977) of mitochondrial DNA.
J Müller-Höcker, U Jacob, P Seibel. Ultrastruct Pathol 1998
J Müller-Höcker, U Jacob, P Seibel. Ultrastruct Pathol 1998
18
Mitochondrial mutations contribute to HIF1alpha accumulation via increased reactive oxygen species and up-regulated pyruvate dehydrogenease kinase 2 in head and neck squamous cell carcinoma.
Wenyue Sun, Shaoyu Zhou, Steven S Chang, Thomas McFate, Ajay Verma, Joseph A Califano. Clin Cancer Res 2009
Wenyue Sun, Shaoyu Zhou, Steven S Chang, Thomas McFate, Ajay Verma, Joseph A Califano. Clin Cancer Res 2009
10
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Ivana Kurelac, Alan MacKay, Maryou B K Lambros, Erica Di Cesare, Giovanna Cenacchi, Claudio Ceccarelli, Isabella Morra, Antonio Melcarne, Luca Morandi, Francesco Maria Calabrese,[...]. Hum Mol Genet 2013
Ivana Kurelac, Alan MacKay, Maryou B K Lambros, Erica Di Cesare, Giovanna Cenacchi, Claudio Ceccarelli, Isabella Morra, Antonio Melcarne, Luca Morandi, Francesco Maria Calabrese,[...]. Hum Mol Genet 2013
20
Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes.
Luisa Iommarini, Maria Antonietta Calvaruso, Ivana Kurelac, Giuseppe Gasparre, Anna Maria Porcelli. Int J Biochem Cell Biol 2013
Luisa Iommarini, Maria Antonietta Calvaruso, Ivana Kurelac, Giuseppe Gasparre, Anna Maria Porcelli. Int J Biochem Cell Biol 2013
16
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells.
Claudia Calabrese, Luisa Iommarini, Ivana Kurelac, Maria Antonietta Calvaruso, Mariantonietta Capristo, Pier-Luigi Lollini, Patrizia Nanni, Christian Bergamini, Giordano Nicoletti, Carla De Giovanni,[...]. Cancer Metab 2013
Claudia Calabrese, Luisa Iommarini, Ivana Kurelac, Maria Antonietta Calvaruso, Mariantonietta Capristo, Pier-Luigi Lollini, Patrizia Nanni, Christian Bergamini, Giordano Nicoletti, Carla De Giovanni,[...]. Cancer Metab 2013
13
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment.
Luisa Iommarini, Ivana Kurelac, Mariantonietta Capristo, Maria Antonietta Calvaruso, Valentina Giorgio, Christian Bergamini, Anna Ghelli, Patrizia Nanni, Carla De Giovanni, Valerio Carelli,[...]. Hum Mol Genet 2014
Luisa Iommarini, Ivana Kurelac, Mariantonietta Capristo, Maria Antonietta Calvaruso, Valentina Giorgio, Christian Bergamini, Anna Ghelli, Patrizia Nanni, Carla De Giovanni, Valerio Carelli,[...]. Hum Mol Genet 2014
12
Hürthle cell tumours of the thyroid. A review with emphasis on mitochondrial abnormalities with clinical relevance.
V Máximo, M Sobrinho-Simões. Virchows Arch 2000
V Máximo, M Sobrinho-Simões. Virchows Arch 2000
8
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer.
Bryan R Haugen, Erik K Alexander, Keith C Bible, Gerard M Doherty, Susan J Mandel, Yuri E Nikiforov, Furio Pacini, Gregory W Randolph, Anna M Sawka, Martin Schlumberger,[...]. Thyroid 2016
Bryan R Haugen, Erik K Alexander, Keith C Bible, Gerard M Doherty, Susan J Mandel, Yuri E Nikiforov, Furio Pacini, Gregory W Randolph, Anna M Sawka, Martin Schlumberger,[...]. Thyroid 2016
8
Chromosomal aberrations by comparative genomic hybridization in hürthle cell thyroid carcinomas are associated with tumor recurrence.
Nobuyuki Wada, Quan-Yang Duh, Daishu Miura, Laurent Brunaud, Mariwil G Wong, Orlo H Clark. J Clin Endocrinol Metab 2002
Nobuyuki Wada, Quan-Yang Duh, Daishu Miura, Laurent Brunaud, Mariwil G Wong, Orlo H Clark. J Clin Endocrinol Metab 2002
15
Mitochondrial DNA mutations in oxyphilic and chief cell parathyroid adenomas.
Jessica Costa-Guda, Takehiko Tokura, Sanford I Roth, Andrew Arnold. BMC Endocr Disord 2007
Jessica Costa-Guda, Takehiko Tokura, Sanford I Roth, Andrew Arnold. BMC Endocr Disord 2007
20
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.