Nicolas Fossat, Gilles Chatelain, Gilbert Brun, Thomas Lamonerie. EMBO Rep 2006
Times Cited: 43
Times Cited: 43
Times Cited
Times Co-cited
Similarity
Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation.
D Acampora, S Mazan, Y Lallemand, V Avantaggiato, M Maury, A Simeone, P Brûlet. Development 1995
D Acampora, S Mazan, Y Lallemand, V Avantaggiato, M Maury, A Simeone, P Brûlet. Development 1995
41
Mouse Otx2 functions in the formation and patterning of rostral head.
I Matsuo, S Kuratani, C Kimura, N Takeda, S Aizawa. Genes Dev 1995
I Matsuo, S Kuratani, C Kimura, N Takeda, S Aizawa. Genes Dev 1995
37
A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain.
S L Ang, O Jin, M Rhinn, N Daigle, L Stevenson, J Rossant. Development 1996
S L Ang, O Jin, M Rhinn, N Daigle, L Stevenson, J Rossant. Development 1996
25
Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.
Akihiro Nishida, Akiko Furukawa, Chieko Koike, Yasuo Tano, Shinichi Aizawa, Isao Matsuo, Takahisa Furukawa. Nat Neurosci 2003
Akihiro Nishida, Akiko Furukawa, Chieko Koike, Yasuo Tano, Shinichi Aizawa, Isao Matsuo, Takahisa Furukawa. Nat Neurosci 2003
25
Heterozygous mutations of OTX2 cause severe ocular malformations.
Nicola K Ragge, Alison G Brown, Charlotte M Poloschek, Birgit Lorenz, R Alex Henderson, Michael P Clarke, Isabelle Russell-Eggitt, Alistair Fielder, Dianne Gerrelli, Juan Pedro Martinez-Barbera,[...]. Am J Hum Genet 2005
Nicola K Ragge, Alison G Brown, Charlotte M Poloschek, Birgit Lorenz, R Alex Henderson, Michael P Clarke, Isabelle Russell-Eggitt, Alistair Fielder, Dianne Gerrelli, Juan Pedro Martinez-Barbera,[...]. Am J Hum Genet 2005
20
Experience-dependent transfer of Otx2 homeoprotein into the visual cortex activates postnatal plasticity.
Sayaka Sugiyama, Ariel A Di Nardo, Shinichi Aizawa, Isao Matsuo, Michel Volovitch, Alain Prochiantz, Takao K Hensch. Cell 2008
Sayaka Sugiyama, Ariel A Di Nardo, Shinichi Aizawa, Isao Matsuo, Michel Volovitch, Alain Prochiantz, Takao K Hensch. Cell 2008
20
A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo.
A Simeone, D Acampora, A Mallamaci, A Stornaiuolo, M R D'Apice, V Nigro, E Boncinelli. EMBO J 1993
A Simeone, D Acampora, A Mallamaci, A Stornaiuolo, M R D'Apice, V Nigro, E Boncinelli. EMBO J 1993
18
Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain.
Eduardo Puelles, Alessandro Annino, Francesca Tuorto, Alessandro Usiello, Dario Acampora, Thomas Czerny, Claude Brodski, Siew-Lan Ang, Wolfgang Wurst, Antonio Simeone. Development 2004
Eduardo Puelles, Alessandro Annino, Francesca Tuorto, Alessandro Usiello, Dario Acampora, Thomas Czerny, Claude Brodski, Siew-Lan Ang, Wolfgang Wurst, Antonio Simeone. Development 2004
16
Functional roles of Otx2 transcription factor in postnatal mouse retinal development.
Chieko Koike, Akihiro Nishida, Shinji Ueno, Hiromitsu Saito, Rikako Sanuki, Shigeru Sato, Akiko Furukawa, Shinichi Aizawa, Isao Matsuo, Noboru Suzuki,[...]. Mol Cell Biol 2007
Chieko Koike, Akihiro Nishida, Shinji Ueno, Hiromitsu Saito, Rikako Sanuki, Shigeru Sato, Akiko Furukawa, Shinichi Aizawa, Isao Matsuo, Noboru Suzuki,[...]. Mol Cell Biol 2007
16
A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors.
Nicolas Fossat, Coralie Le Greneur, Francis Béby, Stéphane Vincent, Pierre Godement, Gilles Chatelain, Thomas Lamonerie. BMC Dev Biol 2007
Nicolas Fossat, Coralie Le Greneur, Francis Béby, Stéphane Vincent, Pierre Godement, Gilles Chatelain, Thomas Lamonerie. BMC Dev Biol 2007
16
Molecular dissection reveals decreased activity and not dominant negative effect in human OTX2 mutants.
Gilles Chatelain, Nicolas Fossat, Gilbert Brun, Thomas Lamonerie. J Mol Med (Berl) 2006
Gilles Chatelain, Nicolas Fossat, Gilbert Brun, Thomas Lamonerie. J Mol Med (Berl) 2006
13
Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid.
Chunhui Di, Shaoxi Liao, David C Adamson, Timothy J Parrett, Daniel K Broderick, Qun Shi, Christoph Lengauer, Jordan M Cummins, Victor E Velculescu, Daniel W Fults,[...]. Cancer Res 2005
Chunhui Di, Shaoxi Liao, David C Adamson, Timothy J Parrett, Daniel K Broderick, Qun Shi, Christoph Lengauer, Jordan M Cummins, Victor E Velculescu, Daniel W Fults,[...]. Cancer Res 2005
13
OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas.
David C Adamson, Qun Shi, Matthew Wortham, Paul A Northcott, Chunhui Di, Christopher G Duncan, Jianjun Li, Roger E McLendon, Darell D Bigner, Michael D Taylor,[...]. Cancer Res 2010
David C Adamson, Qun Shi, Matthew Wortham, Paul A Northcott, Chunhui Di, Christopher G Duncan, Jianjun Li, Roger E McLendon, Darell D Bigner, Michael D Taylor,[...]. Cancer Res 2010
13
Genomic amplification of orthodenticle homologue 2 in medulloblastomas.
Kathy Boon, Charles G Eberhart, Gregory J Riggins. Cancer Res 2005
Kathy Boon, Charles G Eberhart, Gregory J Riggins. Cancer Res 2005
13
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus.
S Srinivas, T Watanabe, C S Lin, C M William, Y Tanabe, T M Jessell, F Costantini. BMC Dev Biol 2001
S Srinivas, T Watanabe, C S Lin, C M William, Y Tanabe, T M Jessell, F Costantini. BMC Dev Biol 2001
13
A novel dominant negative mutation of OTX2 associated with combined pituitary hormone deficiency.
Daniel Diaczok, Christopher Romero, Janice Zunich, Ian Marshall, Sally Radovick. J Clin Endocrinol Metab 2008
Daniel Diaczok, Christopher Romero, Janice Zunich, Ian Marshall, Sally Radovick. J Clin Endocrinol Metab 2008
13
Otx2 binding to perineuronal nets persistently regulates plasticity in the mature visual cortex.
Marine Beurdeley, Julien Spatazza, Henry H C Lee, Sayaka Sugiyama, Clémence Bernard, Ariel A Di Nardo, Takao K Hensch, Alain Prochiantz. J Neurosci 2012
Marine Beurdeley, Julien Spatazza, Henry H C Lee, Sayaka Sugiyama, Clémence Bernard, Ariel A Di Nardo, Takao K Hensch, Alain Prochiantz. J Neurosci 2012
13
Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration.
Francis Béby, Michael Housset, Nicolas Fossat, Coralie Le Greneur, Frédéric Flamant, Pierre Godement, Thomas Lamonerie. PLoS One 2010
Francis Béby, Michael Housset, Nicolas Fossat, Coralie Le Greneur, Frédéric Flamant, Pierre Godement, Thomas Lamonerie. PLoS One 2010
16
13
Otx1 and Otx2 define layers and regions in developing cerebral cortex and cerebellum.
G D Frantz, J M Weimann, M E Levin, S K McConnell. J Neurosci 1994
G D Frantz, J M Weimann, M E Levin, S K McConnell. J Neurosci 1994
11
Regulation of Otx2 expression and its functions in mouse forebrain and midbrain.
Daisuke Kurokawa, Hiroshi Kiyonari, Rika Nakayama, Chiharu Kimura-Yoshida, Isao Matsuo, Shinichi Aizawa. Development 2004
Daisuke Kurokawa, Hiroshi Kiyonari, Rika Nakayama, Chiharu Kimura-Yoshida, Isao Matsuo, Shinichi Aizawa. Development 2004
11
OTX2 activates the molecular network underlying retina pigment epithelium differentiation.
Juan Ramón Martínez-Morales, Vincent Dolez, Isabel Rodrigo, Raffaella Zaccarini, Laurence Leconte, Paola Bovolenta, Simon Saule. J Biol Chem 2003
Juan Ramón Martínez-Morales, Vincent Dolez, Isabel Rodrigo, Raffaella Zaccarini, Laurence Leconte, Paola Bovolenta, Simon Saule. J Biol Chem 2003
11
Otx genes are required for tissue specification in the developing eye.
J R Martinez-Morales, M Signore, D Acampora, A Simeone, P Bovolenta. Development 2001
J R Martinez-Morales, M Signore, D Acampora, A Simeone, P Bovolenta. Development 2001
11
Otx dose-dependent integrated control of antero-posterior and dorso-ventral patterning of midbrain.
Eduardo Puelles, Dario Acampora, Emmanuel Lacroix, Massimo Signore, Alessandro Annino, Francesca Tuorto, Stefania Filosa, Giorgio Corte, Wolfgang Wurst, Siew-Lan Ang,[...]. Nat Neurosci 2003
Eduardo Puelles, Dario Acampora, Emmanuel Lacroix, Massimo Signore, Alessandro Annino, Francesca Tuorto, Stefania Filosa, Giorgio Corte, Wolfgang Wurst, Siew-Lan Ang,[...]. Nat Neurosci 2003
11
OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas.
Talitha de Haas, Esmeralda Oussoren, Wieslawa Grajkowska, Marta Perek-Polnik, Mara Popovic, Lorna Zadravec-Zaletel, Marzia Perera, Giorgio Corte, Oliver Wirths, Peter van Sluis,[...]. J Neuropathol Exp Neurol 2006
Talitha de Haas, Esmeralda Oussoren, Wieslawa Grajkowska, Marta Perek-Polnik, Mara Popovic, Lorna Zadravec-Zaletel, Marzia Perera, Giorgio Corte, Oliver Wirths, Peter van Sluis,[...]. J Neuropathol Exp Neurol 2006
11
Heterozygous orthodenticle homeobox 2 mutations are associated with variable pituitary phenotype.
Sumito Dateki, Kitaro Kosaka, Kosei Hasegawa, Hiroyuki Tanaka, Noriyuki Azuma, Susumu Yokoya, Koji Muroya, Masanori Adachi, Toshihiro Tajima, Katsuaki Motomura,[...]. J Clin Endocrinol Metab 2010
Sumito Dateki, Kitaro Kosaka, Kosei Hasegawa, Hiroyuki Tanaka, Noriyuki Azuma, Susumu Yokoya, Koji Muroya, Masanori Adachi, Toshihiro Tajima, Katsuaki Motomura,[...]. J Clin Endocrinol Metab 2010
11
OTX2 mutation in a patient with anophthalmia, short stature, and partial growth hormone deficiency: functional studies using the IRBP, HESX1, and POU1F1 promoters.
Sumito Dateki, Maki Fukami, Naoko Sato, Kouji Muroya, Masanori Adachi, Tsutomu Ogata. J Clin Endocrinol Metab 2008
Sumito Dateki, Maki Fukami, Naoko Sato, Kouji Muroya, Masanori Adachi, Tsutomu Ogata. J Clin Endocrinol Metab 2008
11
11
Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice.
Takuichiro Hide, Jun Hatakeyama, Chiharu Kimura-Yoshida, E Tian, Naoki Takeda, Yukitaka Ushio, Toshihiko Shiroishi, Shinichi Aizawa, Isao Matsuo. Development 2002
Takuichiro Hide, Jun Hatakeyama, Chiharu Kimura-Yoshida, E Tian, Naoki Takeda, Yukitaka Ushio, Toshihiko Shiroishi, Shinichi Aizawa, Isao Matsuo. Development 2002
11
Novel heterozygous OTX2 mutations and whole gene deletions in anophthalmia, microphthalmia and coloboma.
Alexander Wyatt, Preeti Bakrania, David J Bunyan, Robert J Osborne, John A Crolla, Alison Salt, Carmen Ayuso, Ruth Newbury-Ecob, Y Abou-Rayyah, J Richard O Collin,[...]. Hum Mutat 2008
Alexander Wyatt, Preeti Bakrania, David J Bunyan, Robert J Osborne, John A Crolla, Alison Salt, Carmen Ayuso, Ruth Newbury-Ecob, Y Abou-Rayyah, J Richard O Collin,[...]. Hum Mutat 2008
11
OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells.
Jens Bunt, Nancy E Hasselt, Danny A Zwijnenburg, Mohamed Hamdi, Jan Koster, Rogier Versteeg, Marcel Kool. Int J Cancer 2012
Jens Bunt, Nancy E Hasselt, Danny A Zwijnenburg, Mohamed Hamdi, Jan Koster, Rogier Versteeg, Marcel Kool. Int J Cancer 2012
11
Loss of Otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration.
Michael Housset, Alexander Samuel, Mohamed Ettaiche, Alexis Bemelmans, Francis Béby, Nathalie Billon, Thomas Lamonerie. J Neurosci 2013
Michael Housset, Alexander Samuel, Mohamed Ettaiche, Alexis Bemelmans, Francis Béby, Nathalie Billon, Thomas Lamonerie. J Neurosci 2013
11
Expression of the Otx2 homeobox gene in the developing mammalian brain: embryonic and adult expression in the pineal gland.
Martin F Rath, Estela Muñoz, Surajit Ganguly, Fabrice Morin, Qiong Shi, David C Klein, Morten Møller. J Neurochem 2006
Martin F Rath, Estela Muñoz, Surajit Ganguly, Fabrice Morin, Qiong Shi, David C Klein, Morten Møller. J Neurochem 2006
9
New Otx2 mRNA isoforms expressed in the mouse brain.
Virginie Courtois, Gilles Chatelain, Zhi-Yan Han, Nicolas Le Novère, Gilbert Brun, Thomas Lamonerie. J Neurochem 2003
Virginie Courtois, Gilles Chatelain, Zhi-Yan Han, Nicolas Le Novère, Gilbert Brun, Thomas Lamonerie. J Neurochem 2003
12
Alternative usage of Otx2 promoters during mouse development.
Nicolas Fossat, Virginie Courtois, Gilles Chatelain, Gilbert Brun, Thomas Lamonerie. Dev Dyn 2005
Nicolas Fossat, Virginie Courtois, Gilles Chatelain, Gilbert Brun, Thomas Lamonerie. Dev Dyn 2005
19
Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors.
Thomas Heimbucher, Christina Murko, Baubak Bajoghli, Narges Aghaallaei, Anja Huber, Ronald Stebegg, Dirk Eberhard, Maria Fink, Antonio Simeone, Thomas Czerny. Mol Cell Biol 2007
Thomas Heimbucher, Christina Murko, Baubak Bajoghli, Narges Aghaallaei, Anja Huber, Ronald Stebegg, Dirk Eberhard, Maria Fink, Antonio Simeone, Thomas Czerny. Mol Cell Biol 2007
10
Cell autonomous and non-cell autonomous functions of Otx2 in patterning the rostral brain.
M Rhinn, A Dierich, M Le Meur, S Ang. Development 1999
M Rhinn, A Dierich, M Le Meur, S Ang. Development 1999
9
Nested expression domains of four homeobox genes in developing rostral brain.
A Simeone, D Acampora, M Gulisano, A Stornaiuolo, E Boncinelli. Nature 1992
A Simeone, D Acampora, M Gulisano, A Stornaiuolo, E Boncinelli. Nature 1992
9
Otx2 regulates subtype specification and neurogenesis in the midbrain.
Bertrand Vernay, Muriel Koch, Flora Vaccarino, James Briscoe, Antonio Simeone, Ryoichiro Kageyama, Siew-Lan Ang. J Neurosci 2005
Bertrand Vernay, Muriel Koch, Flora Vaccarino, James Briscoe, Antonio Simeone, Ryoichiro Kageyama, Siew-Lan Ang. J Neurosci 2005
9
OTX2 loss of function mutation causes anophthalmia and combined pituitary hormone deficiency with a small anterior and ectopic posterior pituitary.
Toshihiro Tajima, Akira Ohtake, Masaya Hoshino, Shin Amemiya, Nozomu Sasaki, Katsura Ishizu, Kenji Fujieda. J Clin Endocrinol Metab 2009
Toshihiro Tajima, Akira Ohtake, Masaya Hoshino, Shin Amemiya, Nozomu Sasaki, Katsura Ishizu, Kenji Fujieda. J Clin Endocrinol Metab 2009
9
Genes differentially expressed in medulloblastoma and fetal brain.
E M Michiels, E Oussoren, M Van Groenigen, E Pauws, P M Bossuyt, P A Voûte, F Baas. Physiol Genomics 1999
E M Michiels, E Oussoren, M Van Groenigen, E Pauws, P M Bossuyt, P A Voûte, F Baas. Physiol Genomics 1999
9
The Otx2 homeoprotein regulates expression from the gonadotropin-releasing hormone proximal promoter.
C G Kelley, G Lavorgna, M E Clark, E Boncinelli, P L Mellon. Mol Endocrinol 2000
C G Kelley, G Lavorgna, M E Clark, E Boncinelli, P L Mellon. Mol Endocrinol 2000
9
Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines.
Jens Bunt, Talitha G de Haas, Nancy E Hasselt, Danny A Zwijnenburg, Jan Koster, Rogier Versteeg, Marcel Kool. Mol Cancer Res 2010
Jens Bunt, Talitha G de Haas, Nancy E Hasselt, Danny A Zwijnenburg, Jan Koster, Rogier Versteeg, Marcel Kool. Mol Cancer Res 2010
11
Medulloblastoma comprises four distinct molecular variants.
Paul A Northcott, Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Charles G Eberhart, Stephen Mack, Eric Bouffet, Steven C Clifford, Cynthia E Hawkins, Pim French,[...]. J Clin Oncol 2011
Paul A Northcott, Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Charles G Eberhart, Stephen Mack, Eric Bouffet, Steven C Clifford, Cynthia E Hawkins, Pim French,[...]. J Clin Oncol 2011
9
A rare de novo nonsense mutation in OTX2 causes early onset retinal dystrophy and pituitary dysfunction.
Robert H Henderson, Kathleen A Williamson, Joanna S Kennedy, Andrew R Webster, Graham E Holder, Anthony G Robson, David R FitzPatrick, Veronica van Heyningen, Anthony T Moore. Mol Vis 2009
Robert H Henderson, Kathleen A Williamson, Joanna S Kennedy, Andrew R Webster, Graham E Holder, Anthony G Robson, David R FitzPatrick, Veronica van Heyningen, Anthony T Moore. Mol Vis 2009
9
An essential role for RAX homeoprotein and NOTCH-HES signaling in Otx2 expression in embryonic retinal photoreceptor cell fate determination.
Yuki Muranishi, Koji Terada, Tatsuya Inoue, Kimiko Katoh, Toshinori Tsujii, Rikako Sanuki, Daisuke Kurokawa, Shinichi Aizawa, Yasuhiro Tamaki, Takahisa Furukawa. J Neurosci 2011
Yuki Muranishi, Koji Terada, Tatsuya Inoue, Kimiko Katoh, Toshinori Tsujii, Rikako Sanuki, Daisuke Kurokawa, Shinichi Aizawa, Yasuhiro Tamaki, Takahisa Furukawa. J Neurosci 2011
9
Canonical Wnt signaling and its antagonist regulate anterior-posterior axis polarization by guiding cell migration in mouse visceral endoderm.
Chiharu Kimura-Yoshida, Hiroshi Nakano, Daiji Okamura, Kazuki Nakao, Shigenobu Yonemura, Jose A Belo, Shinichi Aizawa, Yasuhisa Matsui, Isao Matsuo. Dev Cell 2005
Chiharu Kimura-Yoshida, Hiroshi Nakano, Daiji Okamura, Kazuki Nakao, Shigenobu Yonemura, Jose A Belo, Shinichi Aizawa, Yasuhisa Matsui, Isao Matsuo. Dev Cell 2005
9
OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area.
A Mallamaci, E Di Blas, P Briata, E Boncinelli, G Corte. Mech Dev 1996
A Mallamaci, E Di Blas, P Briata, E Boncinelli, G Corte. Mech Dev 1996
6
Implication of OTX2 in pigment epithelium determination and neural retina differentiation.
P Bovolenta, A Mallamaci, P Briata, G Corte, E Boncinelli. J Neurosci 1997
P Bovolenta, A Mallamaci, P Briata, G Corte, E Boncinelli. J Neurosci 1997
6
Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.
M Rhinn, A Dierich, W Shawlot, R R Behringer, M Le Meur, S L Ang. Development 1998
M Rhinn, A Dierich, W Shawlot, R R Behringer, M Le Meur, S L Ang. Development 1998
6
Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.