A citation-based method for searching scientific literature

Guo Wei, David Twomey, Justin Lamb, Krysta Schlis, Jyoti Agarwal, Ronald W Stam, Joseph T Opferman, Stephen E Sallan, Monique L den Boer, Rob Pieters, Todd R Golub, Scott A Armstrong. Cancer Cell 2006
Times Cited: 377







List of co-cited articles
855 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Justin Lamb, Emily D Crawford, David Peck, Joshua W Modell, Irene C Blat, Matthew J Wrobel, Jim Lerner, Jean-Philippe Brunet, Aravind Subramanian, Kenneth N Ross,[...]. Science 2006
34

A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
Aravind Subramanian, Rajiv Narayan, Steven M Corsello, David D Peck, Ted E Natoli, Xiaodong Lu, Joshua Gould, John F Davis, Andrew A Tubelli, Jacob K Asiedu,[...]. Cell 2017
19

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia.
Erich Piovan, Jiyang Yu, Valeria Tosello, Daniel Herranz, Alberto Ambesi-Impiombato, Ana Carolina Da Silva, Marta Sanchez-Martin, Arianne Perez-Garcia, Isaura Rigo, Mireia Castillo,[...]. Cancer Cell 2013
172
16

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.
Aravind Subramanian, Pablo Tamayo, Vamsi K Mootha, Sayan Mukherjee, Benjamin L Ebert, Michael A Gillette, Amanda Paulovich, Scott L Pomeroy, Todd R Golub, Eric S Lander,[...]. Proc Natl Acad Sci U S A 2005
13

Hallmarks of cancer: the next generation.
Douglas Hanahan, Robert A Weinberg. Cell 2011
13

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators.
Haley Hieronymus, Justin Lamb, Kenneth N Ross, Xiao P Peng, Cristina Clement, Anna Rodina, Maria Nieto, Jinyan Du, Kimberly Stegmaier, Srilakshmi M Raj,[...]. Cancer Cell 2006
406
12

Discovery and preclinical validation of drug indications using compendia of public gene expression data.
Marina Sirota, Joel T Dudley, Jeewon Kim, Annie P Chiang, Alex A Morgan, Alejandro Sweet-Cordero, Julien Sage, Atul J Butte. Sci Transl Med 2011
487
11

Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease.
Joel T Dudley, Marina Sirota, Mohan Shenoy, Reetesh K Pai, Silke Roedder, Annie P Chiang, Alex A Morgan, Minnie M Sarwal, Pankaj Jay Pasricha, Atul J Butte. Sci Transl Med 2011
389
11

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia.
Yu Liu, John Easton, Ying Shao, Jamie Maciaszek, Zhaoming Wang, Mark R Wilkinson, Kelly McCastlain, Michael Edmonson, Stanley B Pounds, Lei Shi,[...]. Nat Genet 2017
443
11

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia.
Pedro J Real, Valeria Tosello, Teresa Palomero, Mireia Castillo, Eva Hernando, Elisa de Stanchina, Maria Luisa Sulis, Kelly Barnes, Catherine Sawai, Irene Homminga,[...]. Nat Med 2009
330
11


Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2.
Michael I Love, Wolfgang Huber, Simon Anders. Genome Biol 2014
10

Exploiting drug-disease relationships for computational drug repositioning.
Joel T Dudley, Tarangini Deshpande, Atul J Butte. Brief Bioinform 2011
276
9

Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival.
S Wuillème-Toumi, N Robillard, P Gomez, P Moreau, S Le Gouill, H Avet-Loiseau, J-L Harousseau, M Amiot, R Bataille. Leukemia 2005
246
9

Glucocorticoid use in acute lymphoblastic leukaemia.
Hiroto Inaba, Ching-Hon Pui. Lancet Oncol 2010
209
9

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia.
Alejandro Gutierrez, Takaomi Sanda, Ruta Grebliunaite, Arkaitz Carracedo, Leonardo Salmena, Yebin Ahn, Suzanne Dahlberg, Donna Neuberg, Lisa A Moreau, Stuart S Winter,[...]. Blood 2009
327
9

Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment.
Amy Holleman, Meyling H Cheok, Monique L den Boer, Wenjian Yang, Anjo J P Veerman, Karin M Kazemier, Deqing Pei, Cheng Cheng, Ching-Hon Pui, Mary V Relling,[...]. N Engl J Med 2004
446
8

The landscape of somatic copy-number alteration across human cancers.
Rameen Beroukhim, Craig H Mermel, Dale Porter, Guo Wei, Soumya Raychaudhuri, Jerry Donovan, Jordi Barretina, Jesse S Boehm, Jennifer Dobson, Mitsuyoshi Urashima,[...]. Nature 2010
8

JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias.
C Delgado-Martin, L K Meyer, B J Huang, K A Shimano, M S Zinter, J V Nguyen, G A Smith, J Taunton, S S Winter, J R Roderick,[...]. Leukemia 2017
73
10

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia.
Sofie Peirs, Filip Matthijssens, Steven Goossens, Inge Van de Walle, Katia Ruggero, Charles E de Bock, Sandrine Degryse, Kirsten Canté-Barrett, Delphine Briot, Emmanuelle Clappier,[...]. Blood 2014
149
8

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.
Jinghui Zhang, Li Ding, Linda Holmfeldt, Gang Wu, Sue L Heatley, Debbie Payne-Turner, John Easton, Xiang Chen, Jianmin Wang, Michael Rusch,[...]. Nature 2012
8

Maturation stage of T-cell acute lymphoblastic leukemia determines BCL-2 versus BCL-XL dependence and sensitivity to ABT-199.
Triona Ni Chonghaile, Justine E Roderick, Cian Glenfield, Jeremy Ryan, Stephen E Sallan, Lewis B Silverman, Mignon L Loh, Stephen P Hunger, Brent Wood, Daniel J DeAngelo,[...]. Cancer Discov 2014
142
8

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia.
Teresa Palomero, Maria Luisa Sulis, Maria Cortina, Pedro J Real, Kelly Barnes, Maria Ciofani, Esther Caparros, Jean Buteau, Kristy Brown, Sherrie L Perkins,[...]. Nat Med 2007
672
8

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Gaëtane Le Toumelin-Braizat, Maïa Chanrion, Gemma L Kelly, Jia-Nan Gong, Donia M Moujalled,[...]. Nature 2016
615
8

Drug repurposing: progress, challenges and recommendations.
Sudeep Pushpakom, Francesco Iorio, Patrick A Eyers, K Jane Escott, Shirley Hopper, Andrew Wells, Andrew Doig, Tim Guilliams, Joanna Latimer, Christine McNamee,[...]. Nat Rev Drug Discov 2019
8

mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass.
Steven D Kunkel, Manish Suneja, Scott M Ebert, Kale S Bongers, Daniel K Fox, Sharon E Malmberg, Fariborz Alipour, Richard K Shields, Christopher M Adams. Cell Metab 2011
213
7

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Jordi Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A Margolin, Sungjoon Kim, Christopher J Wilson, Joseph Lehár, Gregory V Kryukov, Dmitriy Sonkin,[...]. Nature 2012
7

Synergistic Drug Combinations with a CDK4/6 Inhibitor in T-cell Acute Lymphoblastic Leukemia.
Yana Pikman, Gabriela Alexe, Giovanni Roti, Amy Saur Conway, Andrew Furman, Emily S Lee, Andrew E Place, Sunkyu Kim, Chitra Saran, Rebecca Modiste,[...]. Clin Cancer Res 2017
68
10

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.
Andrew P Weng, Adolfo A Ferrando, Woojoong Lee, John P Morris, Lewis B Silverman, Cheryll Sanchez-Irizarry, Stephen C Blacklow, A Thomas Look, Jon C Aster. Science 2004
7


Identification of small molecules enhancing autophagic function from drug network analysis.
Francesco Iorio, Antonella Isacchi, Diego di Bernardo, Nicola Brunetti-Pierri. Autophagy 2010
222
7

Drug repositioning: identifying and developing new uses for existing drugs.
Ted T Ashburn, Karl B Thor. Nat Rev Drug Discov 2004
7

Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia.
Duohui Jing, Yizhou Huang, Xiaoyun Liu, Keith C S Sia, Julia C Zhang, Xiaolu Tai, Meng Wang, Cara E Toscan, Hannah McCalmont, Kathryn Evans,[...]. Cancer Cell 2018
38
18


Functional discovery via a compendium of expression profiles.
T R Hughes, M J Marton, A R Jones, C J Roberts, R Stoughton, C D Armour, H A Bennett, E Coffey, H Dai, Y D He,[...]. Cell 2000
6

Drug target identification using side-effect similarity.
Monica Campillos, Michael Kuhn, Anne-Claude Gavin, Lars Juhl Jensen, Peer Bork. Science 2008
803
6

Applications of Connectivity Map in drug discovery and development.
Xiaoyan A Qu, Deepak K Rajpal. Drug Discov Today 2012
153
6

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability.
Ana Silva, J Andrés Yunes, Bruno A Cardoso, Leila R Martins, Patrícia Y Jotta, Miguel Abecasis, Alexandre E Nowill, Nick R Leslie, Angelo A Cardoso, Joao T Barata. J Clin Invest 2008
332
6

Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Chong Zhang, Yong-Ku Ryu, Taylor Z Chen, Connor P Hall, Daniel R Webster, Min H Kang. Leuk Res 2012
30
20

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells.
Duohui Jing, Vivek A Bhadri, Dominik Beck, Julie A I Thoms, Nurul A Yakob, Jason W H Wong, Kathy Knezevic, John E Pimanda, Richard B Lock. Blood 2015
78
7

Targeting nonclassical oncogenes for therapy in T-ALL.
Prem S Subramaniam, Dosh W Whye, Evgeni Efimenko, Jianchung Chen, Valeria Tosello, Kim De Keersmaecker, Adam Kashishian, Mary Ann Thompson, Mireia Castillo, Carlos Cordon-Cardo,[...]. Cancer Cell 2012
74
8

Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics.
Michio Iwata, Ryusuke Sawada, Hiroaki Iwata, Masaaki Kotera, Yoshihiro Yamanishi. Sci Rep 2017
29
20

L1000CDS2: LINCS L1000 characteristic direction signatures search engine.
Qiaonan Duan, St Patrick Reid, Neil R Clark, Zichen Wang, Nicolas F Fernandez, Andrew D Rouillard, Ben Readhead, Sarah R Tritsch, Rachel Hodos, Marc Hafner,[...]. NPJ Syst Biol Appl 2016
139
6

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
Elaine Coustan-Smith, Charles G Mullighan, Mihaela Onciu, Frederick G Behm, Susana C Raimondi, Deqing Pei, Cheng Cheng, Xiaoping Su, Jeffrey E Rubnitz, Giuseppe Basso,[...]. Lancet Oncol 2009
575
6

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).
J D Leverson, H Zhang, J Chen, S K Tahir, D C Phillips, J Xue, P Nimmer, S Jin, M Smith, Y Xiao,[...]. Cell Death Dis 2015
319
6

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Ingrid E Wertz, Saritha Kusam, Cynthia Lam, Toru Okamoto, Wendy Sandoval, Daniel J Anderson, Elizabeth Helgason, James A Ernst, Mike Eby, Jinfeng Liu,[...]. Nature 2011
587
6

A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia.
Haley E Ramsey, Melissa A Fischer, Taekyu Lee, Agnieszka E Gorska, Maria Pia Arrate, Londa Fuller, Kelli L Boyd, Stephen A Strickland, John Sensintaffar, Leah J Hogdal,[...]. Cancer Discov 2018
185
6

The Molecular Signatures Database (MSigDB) hallmark gene set collection.
Arthur Liberzon, Chet Birger, Helga Thorvaldsdóttir, Mahmoud Ghandi, Jill P Mesirov, Pablo Tamayo. Cell Syst 2015
6

MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
Courtney L Jones, Christy M Gearheart, Susan Fosmire, Cristina Delgado-Martin, Nikki A Evensen, Karen Bride, Angela J Waanders, Faye Pais, Jinhua Wang, Teena Bhatla,[...]. Blood 2015
75
8

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.
Steven W Paugh, Erik J Bonten, Daniel Savic, Laura B Ramsey, William E Thierfelder, Prajwal Gurung, R K Subbarao Malireddi, Marcelo Actis, Anand Mayasundari, Jaeki Min,[...]. Nat Genet 2015
95
6


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.