A citation-based method for searching scientific literature

S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
Times Cited: 527







List of co-cited articles
1078 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Guanylin: an endogenous activator of intestinal guanylate cyclase.
M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
497
41

Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
296
37

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, Scott A Waldman. J Clin Invest 2011
100
30



Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Shalina Mahajan-Miklos, Christine M Pierce, Robert M Solinga, Li Jing Sun,[...]. Eur J Pharmacol 2010
147
23

Familial diarrhea syndrome caused by an activating GUCY2C mutation.
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
125
23

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
William D Chey, Anthony J Lembo, Bernard J Lavins, Steven J Shiff, Caroline B Kurtz, Mark G Currie, James E MacDougall, Xinwei D Jia, James Z Shao, Donald A Fitch,[...]. Am J Gastroenterol 2012
272
23

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman. Gastroenterology 2010
81
27

Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
170
22

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
Peng Li, Jieru E Lin, Inna Chervoneva, Stephanie Schulz, Scott A Waldman, Giovanni M Pitari. Am J Pathol 2007
87
25

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Christine M Pierce, Robert M Solinga, Jenny V Tobin, Shalina Mahajan-Miklos,[...]. Life Sci 2010
120
21

Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C.
Hila Romi, Idan Cohen, Daniella Landau, Suliman Alkrinawi, Baruch Yerushalmi, Reli Hershkovitz, Nitza Newman-Heiman, Garry R Cutting, Rivka Ofir, Sara Sivan,[...]. Am J Hum Genet 2012
59
35

A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.
Satish Rao, Anthony J Lembo, Steven J Shiff, Bernard J Lavins, Mark G Currie, Xinwei D Jia, Kelvin Shi, James E MacDougall, James Z Shao, Paul Eng,[...]. Am J Gastroenterol 2012
245
21

Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion.
E A Mann, M L Jump, J Wu, E Yee, R A Giannella. Biochem Biophys Res Commun 1997
106
20

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Peng Li, Stephanie Schulz, Alessandro Bombonati, Juan P Palazzo, Terry M Hyslop, Yihuan Xu, Amy A Baran, Linda D Siracusa, Giovanni M Pitari, Scott A Waldman. Gastroenterology 2007
101
20

Guanylyl cyclases and signaling by cyclic GMP.
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
905
20

Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.
Xiaonan Han, Elizabeth Mann, Shila Gilbert, Yanfang Guan, Kris A Steinbrecher, Marshall H Montrose, Mitchell B Cohen. PLoS One 2011
61
32

Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
349
19

Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.
Kris A Steinbrecher, Steve A Wowk, Jeffrey A Rudolph, David P Witte, Mitchell B Cohen. Am J Pathol 2002
84
22

Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
127
19

GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz,[...]. PLoS One 2012
59
30


Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.
H Eutamene, S Bradesi, M Larauche, V Theodorou, C Beaufrand, G Ohning, J Fioramonti, M Cohen, A P Bryant, C Kurtz,[...]. Neurogastroenterol Motil 2010
134
17

Expression of guanylin is downregulated in mouse and human intestinal adenomas.
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
67
23

Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II.
A Pfeifer, A Aszódi, U Seidler, P Ruth, F Hofmann, R Fässler. Science 1996
313
16

Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation.
Jeffrey M Johnston, Caroline B Kurtz, James E Macdougall, Bernard J Lavins, Mark G Currie, Donald A Fitch, Chris O'Dea, Mollie Baird, Anthony J Lembo. Gastroenterology 2010
161
16

Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues.
S L Carrithers, M T Barber, S Biswas, S J Parkinson, P K Park, S D Goldstein, S A Waldman. Proc Natl Acad Sci U S A 1996
178
16

Two randomized trials of linaclotide for chronic constipation.
Anthony J Lembo, Harvey A Schneier, Steven J Shiff, Caroline B Kurtz, James E MacDougall, Xinwei D Jia, James Z Shao, Bernard J Lavins, Mark G Currie, Donald A Fitch,[...]. N Engl J Med 2011
222
16

Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
A C Chao, F J de Sauvage, Y J Dong, J A Wagner, D V Goeddel, P Gardner. EMBO J 1994
213
15

Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
73
20

Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Joel Castro, Andrea M Harrington, Patrick A Hughes, Christopher M Martin, Pei Ge, Courtney M Shea, Hong Jin, Sarah Jacobson, Gerhard Hannig, Elizabeth Mann,[...]. Gastroenterology 2013
166
15

Bacterial enterotoxins are associated with resistance to colon cancer.
G M Pitari, L V Zingman, D M Hodgson, A E Alekseev, S Kazerounian, M Bienengraeber, G Hajnóczky, A Terzic, S A Waldman. Proc Natl Acad Sci U S A 2003
116
14

Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon.
A B Vaandrager, A G Bot, P Ruth, A Pfeifer, F Hofmann, H R De Jonge. Gastroenterology 2000
96
14

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer.
Chantell Wilson, Jieru E Lin, Peng Li, Adam E Snook, Jianping Gong, Takahiro Sato, Chengbao Liu, Melanie A Girondo, Hallgeir Rui, Terry Hyslop,[...]. Cancer Epidemiol Biomarkers Prev 2014
35
40

Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Jieru E Lin, Francheska Colon-Gonzalez, Erik Blomain, Gilbert W Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E Snook, Tingting Zhan, Terry M Hyslop,[...]. Cancer Res 2016
38
36

Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor.
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
71
18

Characterization of human uroguanylin: a member of the guanylin peptide family.
T Kita, C E Smith, K F Fok, K L Duffin, W M Moore, P J Karabatsos, J F Kachur, F K Hamra, N V Pidhorodeckyj, L R Forte. Am J Physiol 1994
118
13

The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease.
Øystein Brenna, Torunn Bruland, Marianne W Furnes, Atle van Beelen Granlund, Ignat Drozdov, Johanna Emgård, Gunnar Brønstad, Mark Kidd, Arne K Sandvik, Björn I Gustafsson. Scand J Gastroenterol 2015
35
37

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity.
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
95
12

Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
Ruth Birbe, Juan P Palazzo, Rhonda Walters, David Weinberg, Stephanie Schulz, Scott A Waldman. Hum Pathol 2005
92
13

Receptor guanylyl cyclase C (GC-C): regulation and signal transduction.
Nirmalya Basu, Najla Arshad, Sandhya S Visweswariah. Mol Cell Biochem 2010
45
24

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.
John N Lorenz, Michelle Nieman, Jenine Sabo, L Philip Sanford, Jennifer A Hawkins, Noeet Elitsur, Lara R Gawenis, Lane L Clarke, Mitchell B Cohen. J Clin Invest 2003
74
14


Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer.
B Cagir, A Gelmann, J Park, T Fava, A Tankelevitch, E W Bittner, E J Weaver, J P Palazzo, D Weinberg, R D Fry,[...]. Ann Intern Med 1999
97
11

Murine guanylate cyclase C regulates colonic injury and inflammation.
Kris A Steinbrecher, Eleana Harmel-Laws, Monica P Garin-Laflam, Elizabeth A Mann, Lucas D Bezerra, Simon P Hogan, Mitchell B Cohen. J Immunol 2011
41
26


Intestinal cell proliferation and senescence are regulated by receptor guanylyl cyclase C and p21.
Nirmalya Basu, Sayanti Saha, Imran Khan, Subbaraya G Ramachandra, Sandhya S Visweswariah. J Biol Chem 2014
33
33

Efficacy of linaclotide for patients with chronic constipation.
Anthony J Lembo, Caroline B Kurtz, James E Macdougall, B J Lavins, Mark G Currie, Donald A Fitch, Brenda I Jeglinski, Jeffrey M Johnston. Gastroenterology 2010
151
10



Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.