A citation-based method for searching scientific literature

S Schulz, C K Green, P S Yuen, D L Garbers. Cell 1990
Times Cited: 524







List of co-cited articles
1047 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Guanylin: an endogenous activator of intestinal guanylate cyclase.
M G Currie, K F Fok, J Kato, R J Moore, F K Hamra, K L Duffin, C E Smith. Proc Natl Acad Sci U S A 1992
495
42

Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase.
F K Hamra, L R Forte, S L Eber, N V Pidhorodeckyj, W J Krause, R H Freeman, D T Chin, J A Tompkins, K F Fok, C E Smith. Proc Natl Acad Sci U S A 1993
296
39

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
Michael A Valentino, Jieru E Lin, Adam E Snook, Peng Li, Gilbert W Kim, Glen Marszalowicz, Michael S Magee, Terry Hyslop, Stephanie Schulz, Scott A Waldman. J Clin Invest 2011
96
29



The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Jieru Egeria Lin, Peng Li, Adam Eugene Snook, Stephanie Schulz, Abhijit Dasgupta, Terry Marie Hyslop, Ahmara Vivian Gibbons, Glen Marszlowicz, Giovanni Mario Pitari, Scott Arthur Waldman. Gastroenterology 2010
79
29

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
Peng Li, Jieru E Lin, Inna Chervoneva, Stephanie Schulz, Scott A Waldman, Giovanni M Pitari. Am J Pathol 2007
85
27

Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Robert W Busby, Alexander P Bryant, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Shalina Mahajan-Miklos, Christine M Pierce, Robert M Solinga, Li Jing Sun,[...]. Eur J Pharmacol 2010
140
23

Linaclotide for irritable bowel syndrome with constipation: a 26-week, randomized, double-blind, placebo-controlled trial to evaluate efficacy and safety.
William D Chey, Anthony J Lembo, Bernard J Lavins, Steven J Shiff, Caroline B Kurtz, Mark G Currie, James E MacDougall, Xinwei D Jia, James Z Shao, Donald A Fitch,[...]. Am J Gastroenterol 2012
263
23

Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion.
E A Mann, M L Jump, J Wu, E Yee, R A Giannella. Biochem Biophys Res Commun 1997
106
22

Familial diarrhea syndrome caused by an activating GUCY2C mutation.
Torunn Fiskerstrand, Najla Arshad, Bjørn Ivar Haukanes, Rune Rose Tronstad, Khanh Do-Cong Pham, Stefan Johansson, Bjarte Håvik, Siv L Tønder, Shawn E Levy, Damien Brackman,[...]. N Engl J Med 2012
117
22

Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP.
K Shailubhai, H H Yu, K Karunanandaa, J Y Wang, S L Eber, Y Wang, N S Joo, H D Kim, B W Miedema, S Z Abbas,[...]. Cancer Res 2000
169
21

Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Peng Li, Stephanie Schulz, Alessandro Bombonati, Juan P Palazzo, Terry M Hyslop, Yihuan Xu, Amy A Baran, Linda D Siracusa, Giovanni M Pitari, Scott A Waldman. Gastroenterology 2007
101
21

A 12-week, randomized, controlled trial with a 4-week randomized withdrawal period to evaluate the efficacy and safety of linaclotide in irritable bowel syndrome with constipation.
Satish Rao, Anthony J Lembo, Steven J Shiff, Bernard J Lavins, Mark G Currie, Xinwei D Jia, Kelvin Shi, James E MacDougall, James Z Shao, Paul Eng,[...]. Am J Gastroenterol 2012
237
21

Linaclotide is a potent and selective guanylate cyclase C agonist that elicits pharmacological effects locally in the gastrointestinal tract.
Alexander P Bryant, Robert W Busby, Wilmin P Bartolini, Etchell A Cordero, Gerhard Hannig, Marco M Kessler, Christine M Pierce, Robert M Solinga, Jenny V Tobin, Shalina Mahajan-Miklos,[...]. Life Sci 2010
118
20

Guanylyl cyclases and signaling by cyclic GMP.
K A Lucas, G M Pitari, S Kazerounian, I Ruiz-Stewart, J Park, S Schulz, K P Chepenik, S A Waldman. Pharmacol Rev 2000
906
20

Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C.
Hila Romi, Idan Cohen, Daniella Landau, Suliman Alkrinawi, Baruch Yerushalmi, Reli Hershkovitz, Nitza Newman-Heiman, Garry R Cutting, Rivka Ofir, Sara Sivan,[...]. Am J Hum Genet 2012
57
35

Loss of guanylyl cyclase C (GCC) signaling leads to dysfunctional intestinal barrier.
Xiaonan Han, Elizabeth Mann, Shila Gilbert, Yanfang Guan, Kris A Steinbrecher, Marshall H Montrose, Mitchell B Cohen. PLoS One 2011
61
32

Role of cyclic GMP in the action of heat-stable enterotoxin of Escherichia coli.
J M Hughes, F Murad, B Chang, R L Guerrant. Nature 1978
348
19

Targeted inactivation of the mouse guanylin gene results in altered dynamics of colonic epithelial proliferation.
Kris A Steinbrecher, Steve A Wowk, Jeffrey A Rudolph, David P Witte, Mitchell B Cohen. Am J Pathol 2002
84
22

Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells.
G M Pitari, M D Di Guglielmo, J Park, S Schulz, S A Waldman. Proc Natl Acad Sci U S A 2001
125
19

Guanylate cyclase C-mediated antinociceptive effects of linaclotide in rodent models of visceral pain.
H Eutamene, S Bradesi, M Larauche, V Theodorou, C Beaufrand, G Ohning, J Fioramonti, M Cohen, A P Bryant, C Kurtz,[...]. Neurogastroenterol Motil 2010
131
18

GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Jieru Egeria Lin, Adam Eugene Snook, Peng Li, Brian Arthur Stoecker, Gilbert Won Kim, Michael Sullivan Magee, Alex Vladimir Mejia Garcia, Michael Anthony Valentino, Terry Hyslop, Stephanie Schulz,[...]. PLoS One 2012
59
30

Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues.
S L Carrithers, M T Barber, S Biswas, S J Parkinson, P K Park, S D Goldstein, S A Waldman. Proc Natl Acad Sci U S A 1996
177
17


Expression of guanylin is downregulated in mouse and human intestinal adenomas.
K A Steinbrecher, T M Tuohy, K Heppner Goss, M C Scott, D P Witte, J Groden, M B Cohen. Biochem Biophys Res Commun 2000
66
24

Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II.
A Pfeifer, A Aszódi, U Seidler, P Ruth, F Hofmann, R Fässler. Science 1996
308
16

Linaclotide improves abdominal pain and bowel habits in a phase IIb study of patients with irritable bowel syndrome with constipation.
Jeffrey M Johnston, Caroline B Kurtz, James E Macdougall, Bernard J Lavins, Mark G Currie, Donald A Fitch, Chris O'Dea, Mollie Baird, Anthony J Lembo. Gastroenterology 2010
155
16

Two randomized trials of linaclotide for chronic constipation.
Anthony J Lembo, Harvey A Schneier, Steven J Shiff, Caroline B Kurtz, James E MacDougall, Xinwei D Jia, James Z Shao, Bernard J Lavins, Mark G Currie, Donald A Fitch,[...]. N Engl J Med 2011
217
16

Activation of intestinal CFTR Cl- channel by heat-stable enterotoxin and guanylin via cAMP-dependent protein kinase.
A C Chao, F J de Sauvage, Y J Dong, J A Wagner, D V Goeddel, P Gardner. EMBO J 1994
213
15

Guanylin mRNA expression in human intestine and colorectal adenocarcinoma.
M B Cohen, J A Hawkins, D P Witte. Lab Invest 1998
74
20

Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Joel Castro, Andrea M Harrington, Patrick A Hughes, Christopher M Martin, Pei Ge, Courtney M Shea, Hong Jin, Sarah Jacobson, Gerhard Hannig, Elizabeth Mann,[...]. Gastroenterology 2013
160
15

Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon.
A B Vaandrager, A G Bot, P Ruth, A Pfeifer, F Hofmann, H R De Jonge. Gastroenterology 2000
95
14

The paracrine hormone for the GUCY2C tumor suppressor, guanylin, is universally lost in colorectal cancer.
Chantell Wilson, Jieru E Lin, Peng Li, Adam E Snook, Jianping Gong, Takahiro Sato, Chengbao Liu, Melanie A Girondo, Hallgeir Rui, Terry Hyslop,[...]. Cancer Epidemiol Biomarkers Prev 2014
33
42

Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Jieru E Lin, Francheska Colon-Gonzalez, Erik Blomain, Gilbert W Kim, Amanda Aing, Brian Stoecker, Justin Rock, Adam E Snook, Tingting Zhan, Terry M Hyslop,[...]. Cancer Res 2016
38
36

Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor.
Stephen L Carrithers, Cobern E Ott, Michael J Hill, Brett R Johnson, Weiyan Cai, Jason J Chang, Rajesh G Shah, Congmei Sun, Elizabeth A Mann, Manasses C Fonteles,[...]. Kidney Int 2004
71
18

Bacterial enterotoxins are associated with resistance to colon cancer.
G M Pitari, L V Zingman, D M Hodgson, A E Alekseev, S Kazerounian, M Bienengraeber, G Hajnóczky, A Terzic, S A Waldman. Proc Natl Acad Sci U S A 2003
115
13

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load.
John N Lorenz, Michelle Nieman, Jenine Sabo, L Philip Sanford, Jennifer A Hawkins, Noeet Elitsur, Lara R Gawenis, Lane L Clarke, Mitchell B Cohen. J Clin Invest 2003
74
16

Characterization of human uroguanylin: a member of the guanylin peptide family.
T Kita, C E Smith, K F Fok, K L Duffin, W M Moore, P J Karabatsos, J F Kachur, F K Hamra, N V Pidhorodeckyj, L R Forte. Am J Physiol 1994
117
12

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity.
F K Hamra, S L Eber, D T Chin, M G Currie, L R Forte. Proc Natl Acad Sci U S A 1997
95
12

Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
Ruth Birbe, Juan P Palazzo, Rhonda Walters, David Weinberg, Stephanie Schulz, Scott A Waldman. Hum Pathol 2005
91
13

The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease.
Øystein Brenna, Torunn Bruland, Marianne W Furnes, Atle van Beelen Granlund, Ignat Drozdov, Johanna Emgård, Gunnar Brønstad, Mark Kidd, Arne K Sandvik, Björn I Gustafsson. Scand J Gastroenterol 2015
33
36


Guanylyl cyclase C messenger RNA is a biomarker for recurrent stage II colorectal cancer.
B Cagir, A Gelmann, J Park, T Fava, A Tankelevitch, E W Bittner, E J Weaver, J P Palazzo, D Weinberg, R D Fry,[...]. Ann Intern Med 1999
97
11


Receptor guanylyl cyclase C (GC-C): regulation and signal transduction.
Nirmalya Basu, Najla Arshad, Sandhya S Visweswariah. Mol Cell Biochem 2010
42
23

Efficacy of linaclotide for patients with chronic constipation.
Anthony J Lembo, Caroline B Kurtz, James E Macdougall, B J Lavins, Mark G Currie, Donald A Fitch, Brenda I Jeglinski, Jeffrey M Johnston. Gastroenterology 2010
149
10


Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior.
Rong Gong, Cheng Ding, Ji Hu, Yao Lu, Fei Liu, Elizabeth Mann, Fuqiang Xu, Mitchell B Cohen, Minmin Luo. Science 2011
70
14

Murine guanylate cyclase C regulates colonic injury and inflammation.
Kris A Steinbrecher, Eleana Harmel-Laws, Monica P Garin-Laflam, Elizabeth A Mann, Lucas D Bezerra, Simon P Hogan, Mitchell B Cohen. J Immunol 2011
40
25


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.