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Times Cited: 757
Times Cited
Times Co-cited
Similarity
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity.
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Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration.
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Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators.
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PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease.
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Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease.
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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription.
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Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease.
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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
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Involvement of PGC-1α in the formation and maintenance of neuronal dendritic spines.
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Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons.
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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
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Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease.
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Impaired PGC-1alpha function in muscle in Huntington's disease.
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Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
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A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset.
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PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer's disease model.
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The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease.
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Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.