A citation-based method for searching scientific literature

Joseph A Baur, Kevin J Pearson, Nathan L Price, Hamish A Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V Prabhu, Joanne S Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis, Paul J Pistell, Suresh Poosala, Kevin G Becker, Olivier Boss, Dana Gwinn, Mingyi Wang, Sharan Ramaswamy, Kenneth W Fishbein, Richard G Spencer, Edward G Lakatta, David Le Couteur, Reuben J Shaw, Placido Navas, Pere Puigserver, Donald K Ingram, Rafael de Cabo, David A Sinclair. Nature 2006
Times Cited: 2976







List of co-cited articles
998 articles co-cited >1



Times Cited
  Times     Co-cited
Similarity


Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott,[...]. Cell 2006
32

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Konrad T Howitz, Kevin J Bitterman, Haim Y Cohen, Dudley W Lamming, Siva Lavu, Jason G Wood, Robert E Zipkin, Phuong Chung, Anne Kisielewski, Li-Li Zhang,[...]. Nature 2003
25

Therapeutic potential of resveratrol: the in vivo evidence.
Joseph A Baur, David A Sinclair. Nat Rev Drug Discov 2006
20

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function.
Nathan L Price, Ana P Gomes, Alvin J Y Ling, Filipe V Duarte, Alejandro Martin-Montalvo, Brian J North, Beamon Agarwal, Lan Ye, Giorgio Ramadori, Joao S Teodoro,[...]. Cell Metab 2012
898
16

The hallmarks of aging.
Carlos López-Otín, Maria A Blasco, Linda Partridge, Manuel Serrano, Guido Kroemer. Cell 2013
15

Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span.
Kevin J Pearson, Joseph A Baur, Kaitlyn N Lewis, Leonid Peshkin, Nathan L Price, Nazar Labinskyy, William R Swindell, Davida Kamara, Robin K Minor, Evelyn Perez,[...]. Cell Metab 2008
797
14

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.
Jason G Wood, Blanka Rogina, Siva Lavu, Konrad Howitz, Stephen L Helfand, Marc Tatar, David Sinclair. Nature 2004
13

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Jill C Milne, Philip D Lambert, Simon Schenk, David P Carney, Jesse J Smith, David J Gagne, Lei Jin, Olivier Boss, Robert B Perni, Chi B Vu,[...]. Nature 2007
13

Small molecule SIRT1 activators for the treatment of aging and age-related diseases.
Basil P Hubbard, David A Sinclair. Trends Pharmacol Sci 2014
339
12

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.
Joseph T Rodgers, Carlos Lerin, Wilhelm Haas, Steven P Gygi, Bruce M Spiegelman, Pere Puigserver. Nature 2005
12

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
David E Harrison, Randy Strong, Zelton Dave Sharp, James F Nelson, Clinton M Astle, Kevin Flurkey, Nancy L Nadon, J Erby Wilkinson, Krystyna Frenkel, Christy S Carter,[...]. Nature 2009
11

Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans.
Silvie Timmers, Ellen Konings, Lena Bilet, Riekelt H Houtkooper, Tineke van de Weijer, Gijs H Goossens, Joris Hoeks, Sophie van der Krieken, Dongryeol Ryu, Sander Kersten,[...]. Cell Metab 2011
802
11

Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases.
Sung-Jun Park, Faiyaz Ahmad, Andrew Philp, Keith Baar, Tishan Williams, Haibin Luo, Hengming Ke, Holger Rehmann, Ronald Taussig, Alexandra L Brown,[...]. Cell 2012
872
10

Metformin improves healthspan and lifespan in mice.
Alejandro Martin-Montalvo, Evi M Mercken, Sarah J Mitchell, Hector H Palacios, Patricia L Mote, Morten Scheibye-Knudsen, Ana P Gomes, Theresa M Ward, Robin K Minor, Marie-José Blouin,[...]. Nat Commun 2013
662
10

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes.
M Jang, L Cai, G O Udeani, K V Slowing, C F Thomas, C W Beecher, H H Fong, N R Farnsworth, A D Kinghorn, R G Mehta,[...]. Science 1997
9


Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.
E Morselli, M C Maiuri, M Markaki, E Megalou, A Pasparaki, K Palikaras, A Criollo, L Galluzzi, S A Malik, I Vitale,[...]. Cell Death Dis 2010
403
8

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
Fan Yeung, Jamie E Hoberg, Catherine S Ramsey, Michael D Keller, David R Jones, Roy A Frye, Marty W Mayo. EMBO J 2004
8

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol.
Jee-Hyun Um, Sung-Jun Park, Hyeog Kang, Shutong Yang, Marc Foretz, Michael W McBurney, Myung K Kim, Benoit Viollet, Jay H Chung. Diabetes 2010
474
8

High absorption but very low bioavailability of oral resveratrol in humans.
Thomas Walle, Faye Hsieh, Mark H DeLegge, John E Oatis, U Kristina Walle. Drug Metab Dispos 2004
8


Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease.
LaTonya J Hickson, Larissa G P Langhi Prata, Shane A Bobart, Tamara K Evans, Nino Giorgadze, Shahrukh K Hashmi, Sandra M Herrmann, Michael D Jensen, Qingyi Jia, Kyra L Jordan,[...]. EBioMedicine 2019
232
7

Resveratrol stimulates AMP kinase activity in neurons.
Biplab Dasgupta, Jeffrey Milbrandt. Proc Natl Acad Sci U S A 2007
558
7

Caloric restriction improves health and survival of rhesus monkeys.
Julie A Mattison, Ricki J Colman, T Mark Beasley, David B Allison, Joseph W Kemnitz, George S Roth, Donald K Ingram, Richard Weindruch, Rafael de Cabo, Rozalyn M Anderson. Nat Commun 2017
333
7

Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.
Timothy M Bass, David Weinkove, Koen Houthoofd, David Gems, Linda Partridge. Mech Ageing Dev 2007
292
7

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease.
R Scott Turner, Ronald G Thomas, Suzanne Craft, Christopher H van Dyck, Jacobo Mintzer, Brigid A Reynolds, James B Brewer, Robert A Rissman, Rema Raman, Paul S Aisen. Neurology 2015
295
7

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.
Anne Brunet, Lora B Sweeney, J Fitzhugh Sturgill, Katrin F Chua, Paul L Greer, Yingxi Lin, Hien Tran, Sarah E Ross, Raul Mostoslavsky, Haim Y Cohen,[...]. Science 2004
7



Cardioprotection and lifespan extension by the natural polyamine spermidine.
Tobias Eisenberg, Mahmoud Abdellatif, Sabrina Schroeder, Uwe Primessnig, Slaven Stekovic, Tobias Pendl, Alexandra Harger, Julia Schipke, Andreas Zimmermann, Albrecht Schmidt,[...]. Nat Med 2016
439
7

Calorie restriction mimetics: an emerging research field.
Donald K Ingram, Min Zhu, Jacek Mamczarz, Sige Zou, Mark A Lane, George S Roth, Rafael deCabo. Aging Cell 2006
286
6

Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice.
Randy Strong, Richard A Miller, Clinton M Astle, Joseph A Baur, Rafael de Cabo, Elizabeth Fernandez, Wen Guo, Martin Javors, James L Kirkland, James F Nelson,[...]. J Gerontol A Biol Sci Med Sci 2013
118
6

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Richard A Miller, David E Harrison, C M Astle, Joseph A Baur, Angela Rodriguez Boyd, Rafael de Cabo, Elizabeth Fernandez, Kevin Flurkey, Martin A Javors, James F Nelson,[...]. J Gerontol A Biol Sci Med Sci 2011
572
6

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.
P Puigserver, Z Wu, C W Park, R Graves, M Wright, B M Spiegelman. Cell 1998
6

Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate.
Dario R Valenzano, Eva Terzibasi, Tyrone Genade, Antonino Cattaneo, Luciano Domenici, Alessandro Cellerino. Curr Biol 2006
499
6

Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.
Filipe Cabreiro, Catherine Au, Kit-Yi Leung, Nuria Vergara-Irigaray, Helena M Cochemé, Tahereh Noori, David Weinkove, Eugene Schuster, Nicholas D E Greene, David Gems. Cell 2013
494
6

Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis.
Victoria A Brown, Ketan R Patel, Maria Viskaduraki, James A Crowell, Marjorie Perloff, Tristan D Booth, Grygoriy Vasilinin, Ananda Sen, Anna Maria Schinas, Gianfranca Piccirilli,[...]. Cancer Res 2010
360
6

A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice.
Jamie L Barger, Tsuyoshi Kayo, James M Vann, Edward B Arias, Jelai Wang, Timothy A Hacker, Ying Wang, Daniel Raederstorff, Jason D Morrow, Christiaan Leeuwenburgh,[...]. PLoS One 2008
406
6

Mechanism of inhibition of bovine F1-ATPase by resveratrol and related polyphenols.
Jonathan R Gledhill, Martin G Montgomery, Andrew G W Leslie, John E Walker. Proc Natl Acad Sci U S A 2007
262
6

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential.
Frank Madeo, Didac Carmona-Gutierrez, Sebastian J Hofer, Guido Kroemer. Cell Metab 2019
149
6

Extending healthy life span--from yeast to humans.
Luigi Fontana, Linda Partridge, Valter D Longo. Science 2010
6


Oxidative stress, aging, and diseases.
Ilaria Liguori, Gennaro Russo, Francesco Curcio, Giulia Bulli, Luisa Aran, David Della-Morte, Gaetano Gargiulo, Gianluca Testa, Francesco Cacciatore, Domenico Bonaduce,[...]. Clin Interv Aging 2018
766
6

Bioavailability of resveratrol.
Thomas Walle. Ann N Y Acad Sci 2011
439
6

Resveratrol induces mitochondrial biogenesis in endothelial cells.
Anna Csiszar, Nazar Labinskyy, John T Pinto, Praveen Ballabh, Hanrui Zhang, Gyorgy Losonczy, Kevin Pearson, Rafael de Cabo, Pal Pacher, Cuihua Zhang,[...]. Am J Physiol Heart Circ Physiol 2009
303
6

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.
Sarah J Mitchell, Alejandro Martin-Montalvo, Evi M Mercken, Hector H Palacios, Theresa M Ward, Gelareh Abulwerdi, Robin K Minor, George P Vlasuk, James L Ellis, David A Sinclair,[...]. Cell Rep 2014
219
5

AMPK: a nutrient and energy sensor that maintains energy homeostasis.
D Grahame Hardie, Fiona A Ross, Simon A Hawley. Nat Rev Mol Cell Biol 2012
5

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.
Pál Brasnyó, Gergo A Molnár, Márton Mohás, Lajos Markó, Boglárka Laczy, Judit Cseh, Esztella Mikolás, István András Szijártó, Akos Mérei, Richárd Halmai,[...]. Br J Nutr 2011
404
5

The road ahead for health and lifespan interventions.
Marta Gonzalez-Freire, Alberto Diaz-Ruiz, David Hauser, Jorge Martinez-Romero, Luigi Ferrucci, Michel Bernier, Rafael de Cabo. Ageing Res Rev 2020
26
19

Mechanism of human SIRT1 activation by resveratrol.
Margie T Borra, Brian C Smith, John M Denu. J Biol Chem 2005
725
5


Co-cited is the co-citation frequency, indicating how many articles cite the article together with the query article. Similarity is the co-citation as percentage of the times cited of the query article or the article in the search results, whichever is the lowest. These numbers are calculated for the last 100 citations when articles are cited more than 100 times.